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MRDATATADLQASQPPGLHRFRIHLDIAVVVVVLVLTNLVAHFTTPWASIGTVPAAAVGLVILMRYRGLG WTDLGLGRDHWKSGVGYALAAVAVVAAVIAIGVLLPATRPMFMNNRYATISGAMIASMVVIPVQTVIPEE LAFRGVLHGALNRAWGFRGVALAGSLLFGLWHVATSFGLTSGNVGFTRLFGGGMVGMMAGVTGAVLATGA AGFVFSWLRRRSGSLIAPIALHWSLNGLGALAAAFVWHLST
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2856 | - | - | 100% (251) | caax amino protease family protein |
| M. avium 104 | MAV_0745 | - | 6e-13 | 31.21% (173) | caax amino protease family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1894c | - | 1e-114 | 83.76% (234) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3342 | - | 1e-107 | 74.90% (239) | abortive infection protein |
| M. tuberculosis H37Rv | Rv1863c | - | 1e-114 | 83.76% (234) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0497 | - | 2e-95 | 70.09% (234) | hypothetical protein MAB_0497 |
| M. marinum M | MMAR_2740 | - | 1e-116 | 82.21% (253) | hypothetical protein MMAR_2740 |
| M. smegmatis MC2 155 | MSMEG_3612 | - | 1e-110 | 78.66% (239) | integral membrane protein |
| M. thermoresistible (build 8) | TH_1367 | - | 1e-108 | 77.82% (239) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_0411 | - | 8e-14 | 34.92% (189) | hypothetical protein MUL_0411 |
| M. vanbaalenii PYR-1 | Mvan_3070 | - | 1e-109 | 78.11% (233) | abortive infection protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1894c|M.bovis_AF2122/97 MSDHLTACAAVHPGPLVSHLSVMHRFRIYVDIAVVVLVLVLTNLIAHFTT
Rv1863c|M.tuberculosis_H37Rv MSDHLTACAAVHPGPLVSHLSVMHRFRIYVDIAVVVLVLVLTNLIAHFTT
MMAR_2740|M.marinum_M MRDHAT--TAPHPDPLVTQLSALHRLRIHLDVAVVVVVLVLTNLIAHFTT
MAV_2856|M.avium_104 MRDATA-----TADLQASQPPGLHRFRIHLDIAVVVVVLVLTNLVAHFTT
MSMEG_3612|M.smegmatis_MC2_155 -----M--AAQHPHPLMAQLAALHHFRIYVDIAIVVVVLAMTNLIAHFTT
TH_1367|M.thermoresistible__bu ---------------VVAQLAALSRFRTYVDVAVVVVVLAICNLIAHFTT
Mflv_3342|M.gilvum_PYR-GCK MSDAVA--APPEPHPLAAQLSALQHFRLYVDIAIVVVVLALSNLLAHFTT
Mvan_3070|M.vanbaalenii_PYR-1 MSDAIA--APVEHHPWMGHLSALHHFRIYVDIAIVVVVLALTNLLAHFTT
MAB_0497|M.abscessus_ATCC_1997 --------MPTQTPAAVAPLHGLRDVRTYIDIAVVVAVLVATNLIAHFTT
MUL_0411|M.ulcerans_Agy99 ---------------------------------MVSWSLASPRLPARWR-
:* *. .* *::
Mb1894c|M.bovis_AF2122/97 PWASIATVPAAAVGLVILVRSRGLGWAELGLSRQHWKSGLVYALAAVALV
Rv1863c|M.tuberculosis_H37Rv PWASIATVPAAAVGLVILVRSRGLGWAELGLSRQHWKSGLVYALAAVALV
MMAR_2740|M.marinum_M PWASIATVPAAAVGLVILVRSRGLGWAELGLGREHWRSGMFYALAAVGLV
MAV_2856|M.avium_104 PWASIGTVPAAAVGLVILMRYRGLGWTDLGLGRDHWKSGVGYALAAVAVV
MSMEG_3612|M.smegmatis_MC2_155 PWASIATVPAAAVGLLALARARGWGWTELGLGREHWKTGAGYALAAVGVV
TH_1367|M.thermoresistible__bu PWASVATVPAVAVGLVLLVRSRGLGWAELGLSREHWRSGAGYAAAAVALV
Mflv_3342|M.gilvum_PYR-GCK PWANVAVIPAAAVGLLFMVRSRGLGWSELGLGREHWRSGAGYALGAVALV
Mvan_3070|M.vanbaalenii_PYR-1 PWANIAVVPAAAVGLLLLVRSRGLGWSELGLGREHWKSGAGYALGAVALV
MAB_0497|M.abscessus_ATCC_1997 PWANFVVVPIAAIGLLALIRYRGHSWAELGLGRDHWRSGAKYAAVAVVIV
MUL_0411|M.ulcerans_Agy99 -----VALQAVLGGLLVLVTR-----APLGLTPPRLWAGLRLGAVAAAPV
.: . **: : : *** : :* . *. *
Mb1894c|M.bovis_AF2122/97 VAVISVGVLLPITRPMFMNHHYAT-ISGAVIASMVMIPLQTVIPEELAFR
Rv1863c|M.tuberculosis_H37Rv VAVISVGVLLPITRPMFMNHHYAT-ISGAVIASMVMIPLQTVIPEELAFR
MMAR_2740|M.marinum_M VLVISAGVLLPMTRPMFMNNHYAT-VSGAVIASMVIIPLQTVIPEELAFR
MAV_2856|M.avium_104 AAVIAIGVLLPATRPMFMNNRYAT-ISGAMIASMVVIPVQTVIPEELAFR
MSMEG_3612|M.smegmatis_MC2_155 LSVIAIGALLPWTRPMFMNDNYAT-LSGALIASMIIIPLQTVIPEELAFR
TH_1367|M.thermoresistible__bu LSVIAIGALLPWTRPMFLNNNYAT-ISGALIASMVIIPLQTVIPEELAFR
Mflv_3342|M.gilvum_PYR-GCK GTVIAIGALLPWTRPMFLNNNYAT-LSGALIASMIIIPLQTVIPEELAFR
Mvan_3070|M.vanbaalenii_PYR-1 GTVIAVGVLLPVTRPMFLNDNYAT-LSGALVASMIIIPLQTVIPEELAFR
MAB_0497|M.abscessus_ATCC_1997 GAVIGIGLLLPITRPMFLNSSYATTVSGALLASFVLIPLQTVIPEELAFR
MUL_0411|M.ulcerans_Agy99 ATATAATTPVPMVRLSMSERDLPASVPGWLG---LQIPFGTVWAEEAAFR
. . :* .* : : .: :.* : : **. ** .** ***
Mb1894c|M.bovis_AF2122/97 GVLHGALNRAWGFRGVAVAGSVLFGLWHIATSLGLTSSNVGFTRLFGGGI
Rv1863c|M.tuberculosis_H37Rv GVLHGALNRAWGFRGVAVAGSVLFGLWHIATSLGLTSSNVGFTRLFGGGI
MMAR_2740|M.marinum_M GVLHGALNRAWGFRGVALAGSLLFGLWHVATSLGLTSSNVGFTRLFGGGI
MAV_2856|M.avium_104 GVLHGALNRAWGFRGVALAGSLLFGLWHVATSFGLTSGNVGFTRLFGGGM
MSMEG_3612|M.smegmatis_MC2_155 GVLHGALDRAWGFRGVAAAGSLLFGMWHIATSLGLTSSNVGFTRLFGGGI
TH_1367|M.thermoresistible__bu GVLHGALSRAWGFRGVAAAGSLLFGLWHVATSLGLTSSNVGFTRLFGGGV
Mflv_3342|M.gilvum_PYR-GCK GVLHGALEQAWGWRGVAAAGSLLFGLWHIATSLGLTASNAGFTKILGGGV
Mvan_3070|M.vanbaalenii_PYR-1 GVLHGALDRAWGWRGVAAAGSLLFGLWHIATSLGLTASNVGFTKILGGGV
MAB_0497|M.abscessus_ATCC_1997 GVLHGTMARAWGFRGVAAVGSLLFGFWHIATSLGLTTGNVGLTRLLGVGL
MUL_0411|M.ulcerans_Agy99 AALATMGTRGFGHVGGQLLQAVTFGLSHVADAR-----------------
..* :.:* * :: **: *:* :
Mb1894c|M.bovis_AF2122/97 IGLVAGVMLAVLATGVAGFVFSWLRRRSGSLIAPIALHWSLNGMGALAAA
Rv1863c|M.tuberculosis_H37Rv IGLVAGVMLAVLATGVAGFVFSWLRRRSGSLIAPIALHWSLNGMGALAAA
MMAR_2740|M.marinum_M VGMVAGVVLAVLATGAAGFVFSWLRRRSGSLIAPIALHWSLNGVGALAAA
MAV_2856|M.avium_104 VGMMAGVTGAVLATGAAGFVFSWLRRRSGSLIAPIALHWSLNGLGALAAA
MSMEG_3612|M.smegmatis_MC2_155 LGTVAGVVLAVVATGIAGFVFSWLRRRSGSLLAPIALHWSLNGMGALAAA
TH_1367|M.thermoresistible__bu LGTVAGVVLAVIATAVAGFVFDWLRRRSGSLLAPIALHWSLNGMGALAAA
Mflv_3342|M.gilvum_PYR-GCK FGMVAGVVGAVIATAAAGFVFSWLRRRSGSLIAPIALHWSLNGLGALAAA
Mvan_3070|M.vanbaalenii_PYR-1 FGMVVGVVGAVIATAAAGFVFTWLRRRSGSLIAPIALHWSLNGLGALAAA
MAB_0497|M.abscessus_ATCC_1997 WAQIAGVAGAVVATAIAGFVFTWLRRRSGSLLAPIALHWSLNGMGVLAAV
MUL_0411|M.ulcerans_Agy99 -ATGAPPVPTVLVTGLAGWLFGWLAERSGSLAAPMVLHLAINEAGAVAAL
. . :*:.*. **::* ** .***** **:.** ::* *.:**
Mb1894c|M.bovis_AF2122/97 LVWHLST------------
Rv1863c|M.tuberculosis_H37Rv LVWHLST------------
MMAR_2740|M.marinum_M VVWHLSN------------
MAV_2856|M.avium_104 FVWHLST------------
MSMEG_3612|M.smegmatis_MC2_155 VVWHIST------------
TH_1367|M.thermoresistible__bu LVWHLST------------
Mflv_3342|M.gilvum_PYR-GCK LVWHLS-------------
Mvan_3070|M.vanbaalenii_PYR-1 LVWHLS-------------
MAB_0497|M.abscessus_ATCC_1997 LVWHLI-------------
MUL_0411|M.ulcerans_Agy99 TVQRRWINGAEITPRRRYT
* :