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SRYHQRMRGSKILITGPTGQIATPVARALAADNEVWGIARFTDAAARERLEQAGIRCQTVNLAAGDFTGL PSDFDFVLNLAVAKSGSWDKDLAANAESVGVLMAHCRNAKAFLHCSSAAVYDPPGDEPRSERSALGDNHK PLFPTYSISKIAGEVVARSVARIVGLPTTIARLNVPYGDNGGWPFYHMEMMLSGIPIPVPPGEPARYNPI HEDDIIATIPKLLDVASVPATTVNWCGDQTVSLQEWCGYLGSLVGREPVFEPSERALRGNPTTVDRMHEL IGGTTVDWRDGMRRMAAKFHPELVGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2766 | - | - | 100% (307) | NAD dependent epimerase/dehydratase family protein |
| M. avium 104 | MAV_0921 | - | 2e-72 | 47.49% (299) | hypothetical protein MAV_0921 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2455 | - | 7e-66 | 44.63% (298) | NAD-dependent epimerase/dehydratase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2896 | - | 1e-143 | 80.33% (300) | nucleoside-diphosphate-sugar epimerase WcaG-like protein |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4464 | - | 8e-06 | 24.67% (304) | PUTATIVE NAD-dependent epimerase/dehydratase |
| M. ulcerans Agy99 | MUL_2058 | - | 7e-05 | 23.53% (272) | hypothetical protein MUL_2058 |
| M. vanbaalenii PYR-1 | Mvan_5808 | - | 3e-05 | 24.35% (271) | NAD-dependent epimerase/dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4464|M.thermoresistible__bu --------MALTVAVTGPTGEIGMAAVEALERDPAVGRIVGMARRPFDAA
Mvan_5808|M.vanbaalenii_PYR-1 --------MSLRVAVTGPTGEIGISTISALEAHPAVAEIIGMARRPFDTS
MUL_2058|M.ulcerans_Agy99 --------MGVAVAVTGPTGDIGISAVTALEREPAVASIVGMARRPFDPA
MAV_2766|M.avium_104 MSRYHQRMRGSKILITGPTGQIATPVARALAADNEVWGIARFT----DAA
MMAR_2896|M.marinum_M -------MRDSKILITGVTGQVASPVARALAAANEVWGIARFT----DAT
Mflv_2455|M.gilvum_PYR-GCK ---MSAALRGEKILITGATGKIAFPIARLLAPHNDVWGAARLR----DPA
: :** **.:. . * * : *.:
TH_4464|M.thermoresistible__bu AHGWTKTEYRQGDILDREAVDALVAPADVVVHLAFIIMGSRAESERVNLT
Mvan_5808|M.vanbaalenii_PYR-1 EHGWTKTTYRQGDILDRDAVEALVADTDVVVHLAFIIMGSREESARVNLE
MUL_2058|M.ulcerans_Agy99 IYGWSKTTYQRGNILDRDAVDALVAQADVVVHLAFIKLGSRAESAQVNLQ
MAV_2766|M.avium_104 ARERLEQAGIRCQTVNLAAGDFTGLPSDFDFVLNLAVAK-SGSWDKDLAA
MMAR_2896|M.marinum_M ARADLEQAGIRCQAVNLAAGDFTEIPSDFDYVLNFAVAK-SGNWDKDLGA
Mflv_2455|M.gilvum_PYR-GCK DRDRLTAAGVTPVALDLGTGDVSPLPDDFTYVFHAAVDPGQGEWSRAVET
:: : : *. : . :
TH_4464|M.thermoresistible__bu GTRNVFQAVVDHHARTGRPRRLVYTSSVAAYGYHSDNPVPITESVAPRGS
Mvan_5808|M.vanbaalenii_PYR-1 GTRNVFEAAVAG----PRVRRLVYTSSVAAYGYHSDNPVPITEDVPPRGS
MUL_2058|M.ulcerans_Agy99 GARNVFEATVAAR----RPRRLVYTSSMAAYGYHSDNPAAITEDVPARGS
MAV_2766|M.avium_104 NAESVGVLMAHCR----NAKAFLHCSSAAVYDPPGDEPRSERSALGDNHK
MMAR_2896|M.marinum_M NAESVGLLMAHCR----AAKAFLHCSSAAVYDPPDNELRTENAALGDNHK
Mflv_2455|M.gilvum_PYR-GCK NAQRSGELLHHCR----TAKGFVLCSTGSIYGYQRGRPLTEDDPPG---V
.:. : :: *: : *. .. .
TH_4464|M.thermoresistible__bu PEH-YYSAQKAACEALLAEITDGSGVEVYVLRPCIVAGPRAPALADAMPW
Mvan_5808|M.vanbaalenii_PYR-1 PEH-YYSEQKAACEALLADVTAGSALEVYVLRPCIVAGPKATALADAMPW
MUL_2058|M.ulcerans_Agy99 PEH-YYSEQKAQSEAELAKITEDSLLQVFVLRPCIVAGPHAYSLAEAMPC
MAV_2766|M.avium_104 PLFPTYSISKIAGEVVARSVARIVGLPTTIARLNVPYGDNG-----GWPF
MMAR_2896|M.marinum_M FLFPTYSISKIAGEVVVRSMARVLELPATIARLNVPYGNNG-----GWPF
Mflv_2455|M.gilvum_PYR-GCK PLRANYSFSKVAAEAVCTWVSRHFDIPLTIIRICSTYGPEG-----GAAA
** .* *. :: : : * * .. . .
TH_4464|M.thermoresistible__bu NQLPKPVKRITQALPLLRPPFPDPGTPLQLVHHDDVAEAIRLAATTTSAP
Mvan_5808|M.vanbaalenii_PYR-1 NQLPGPVRRLAHALPLLKPPFPDPGTPVQLVHHDDVASAIVAAVTTTSAQ
MUL_2058|M.ulcerans_Agy99 RQVPAPVRALSRVVPMLKPIVPDPGVPVQLVHHDDVAAAIALAATAP-VP
MAV_2766|M.avium_104 YHMEMMLSGIPIPVPPGEPARYNP------IHEDDIIATIPKLLDVASVP
MMAR_2896|M.marinum_M FHMEMMLAGIPIPVPPGGPARYNP------IHEDDIIATIPKLFAAASVP
Mflv_2455|M.gilvum_PYR-GCK DRLDAILARRPIRLHPDRPNNYNP------IYEDDYVALGIRAMQVARTP
:: : . : * :* ::.** .. .
TH_4464|M.thermoresistible__bu PGAYNIAADGVLSMSQVASALGARPIRVPRAAMTATSELVARLPFIPSTL
Mvan_5808|M.vanbaalenii_PYR-1 PGAYNIAGDGVLSMSAVGEALGARPVRVPHGAATATSEVIARLPFVPSIL
MUL_2058|M.ulcerans_Agy99 AGAYNIAADGVVTITDMARALGGRPVRVPAAAASVASAAISRLPLVPPLL
MAV_2766|M.avium_104 ATTVNWCGDQTVSLQEWCGYLG---SLVGREPVFEPSERALRGNPTTVDR
MMAR_2896|M.marinum_M ATTVNWAGDQIVSLQDWCGYLG---TLIGKEPVFQESDSALRPNPVDVTR
Mflv_2455|M.gilvum_PYR-GCK PQVVNWAGSETVSVEEYCAYLG---ELVGIEPVFEYTADAHTPLWPDVTR
. . * ... ::: ** : . :
TH_4464|M.thermoresistible__bu EWLHVGRTSVVMDVDKAKRLLGWTPTHTAADTLAALAARPT--
Mvan_5808|M.vanbaalenii_PYR-1 EWLHAGRTSVVMDTTKARDQLGWRPNFSAAETLSALASSIGND
MUL_2058|M.ulcerans_Agy99 EWLHAVRQPVVMDTAKAKRELGWSPTHSSAETLSALAAAI---
MAV_2766|M.avium_104 MHELIGGTTVDWRDGMRRMAAKFHPELVGV-------------
MMAR_2896|M.marinum_M MHELIGNTAVDWHDGMRRLVAKFHPEAPGL-------------
Mflv_2455|M.gilvum_PYR-GCK MHEVLGRTKVPWREGFRRMTAARHPELTLSDTCTTS-------
* : *