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VSDRRELRSVARRDVLRLAGAMPVILAAGAVLPGPRAAAGVAGMSVFLDPGHNAVNDASINRPVPNGRGG SKPCQTSGAAADDGYPEHVFTWAVVGLINASLNQMGVHTQLSRADDSGVGPCIDQRADAANAMRPDAIVS IHADGGPASGSGFHVNYSSPPLNDVQAGPAVQLAHAMRDALAQAGFQPATYIGSDGLYGRDDLAGLNLAQ YPAVLVELGNMKNAGDAARMESPDGRAAYAAAVTAGIVAFLNAKAASG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2168 | - | - | 100% (258) | N-acetylmuramoyl-L-alanine amidase |
| M. avium 104 | MAV_0385 | - | 4e-79 | 58.05% (236) | N-acetylmuramoyl-L-alanine amidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3744 | - | 2e-81 | 60.68% (234) | hypothetical protein Mb3744 |
| M. gilvum PYR-GCK | Mflv_1286 | - | 2e-71 | 55.83% (240) | cell wall hydrolase/autolysin |
| M. tuberculosis H37Rv | Rv3717 | - | 2e-81 | 60.68% (234) | hypothetical protein Rv3717 |
| M. leprae Br4923 | MLBr_02331 | - | 1e-77 | 56.57% (251) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_0318c | - | 4e-81 | 64.38% (219) | hypothetical protein MAB_0318c |
| M. marinum M | MMAR_5233 | - | 1e-81 | 61.14% (229) | N-acetylmuramoyl-L-alanine amidase |
| M. smegmatis MC2 155 | MSMEG_6281 | - | 2e-77 | 59.23% (233) | N-acetylmuramoyl-L-alanine amidase |
| M. thermoresistible (build 8) | TH_2289 | - | 8e-83 | 62.08% (240) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4308 | - | 9e-82 | 61.14% (229) | N-acetylmuramoyl-L-alanine amidase |
| M. vanbaalenii PYR-1 | Mvan_5529 | - | 1e-78 | 57.55% (245) | cell wall hydrolase/autolysin |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1286|M.gilvum_PYR-GCK -----MPARLRVGAAL--------AAGMLAASSG--LAAPAQAAPTN---
Mvan_5529|M.vanbaalenii_PYR-1 -----MPAILRVGAAV--------VAAMLVATT---PAGPAQAAPAN---
MSMEG_6281|M.smegmatis_MC2_155 MAAVRVPACLRVGAAV--------VTSVLIAVTASVVSPVAHAAPSN---
TH_2289|M.thermoresistible__bu --VTAVPACLRVGAAFTMRGVAVAVATVLIAAS--VPASPAAAAPSA---
Mb3744|M.bovis_AF2122/97 ---------------M--------IVGVLVAAAT-PIISSASATPAN---
Rv3717|M.tuberculosis_H37Rv ---------------M--------IVGVLVAAAT-PIISSASATPAN---
MMAR_5233|M.marinum_M ---------------M--------VIGMLVAALT-PLLPTAAAAPSN---
MUL_4308|M.ulcerans_Agy99 ---------------M--------VIGMLVAALT-PLLPTAAAAPSN---
MLBr_02331|M.leprae_Br4923 ---MNTRVSLRIGFRM--------VVGLLVAALT-TITPTAVAYPSNPAN
MAB_0318c|M.abscessus_ATCC_199 -----MRVSFWRAAGLAG-------TALLTAASVTVLPVATPSAPTTFTA
MAV_2168|M.avium_104 ---MSDRRELRSVARR-------DVLRLAGAMPVILAAGAVLPGPRAAAG
: * . . *
Mflv_1286|M.gilvum_PYR-GCK -----LAGKIVFLDPGHQGSMEG-LSRQVPTGRGGTKDCQAGGTSTEDGL
Mvan_5529|M.vanbaalenii_PYR-1 -----IAGMIVFLDPGHNGSNDASISRQVPTGRGGTKDCQASGTSTEDGF
MSMEG_6281|M.smegmatis_MC2_155 -----IAGMIVFLDPGHNGANDASIGRQVPTGRGGTKNCQESGTATDDGY
TH_2289|M.thermoresistible__bu -----LAGRIVFLDPGHNGANDASINRQVPTGRGGTKECQTSGSSTDDGY
Mb3744|M.bovis_AF2122/97 -----IAGMVVFIDPGHNGANDASIGRQVPTGRGGTKNCQASGTSTNSGY
Rv3717|M.tuberculosis_H37Rv -----IAGMVVFIDPGHNGANDASIGRQVPTGRGGTKNCQASGTSTNSGY
MMAR_5233|M.marinum_M -----IAGMVVFIDPGHNGANDASIGRQVPTGRGGTKDCQASGTSSNSGY
MUL_4308|M.ulcerans_Agy99 -----IAGMVVFIDPGHNGANDASIGRQVPTGRGGTKDCQASGTSSNSGY
MLBr_02331|M.leprae_Br4923 -----IAGMIVFIDPGHNGSNDASISRQVPTGRGGTKDCQASGTSTNSGY
MAB_0318c|M.abscessus_ATCC_199 GAAPGIAGRIVVLDPGHNGANDSSINNQVPDGRGGTKSCQTSGTATDGGY
MAV_2168|M.avium_104 -----VAGMSVFLDPGHNAVNDASINRPVPNGRGGSKPCQTSGAAADDGY
:** *.:****:. :. :.. ** ****:* ** .*::::.*
Mflv_1286|M.gilvum_PYR-GCK SEHTFAWDTTLRVRQALTALGVRTAMSRGDDTGPGPCVDERAAMANSIRP
Mvan_5529|M.vanbaalenii_PYR-1 AEHTFTWDTTLRVRQALTALGVRTAMSRGDDTGLGPCVDERAAMANALSP
MSMEG_6281|M.smegmatis_MC2_155 PEHSFTWDTTLRVRAALTALGVRTAMSRGNDNALGPCVDERAAMANSLRP
TH_2289|M.thermoresistible__bu PEHTFNWDTTLRIRAALHQLGVRTAMSRGNDNALGPCVDERAAMANSLKP
Mb3744|M.bovis_AF2122/97 PEHTFTWETGLRLRAALNALGVRTALSRGNDNALGPCVDERANMANALRP
Rv3717|M.tuberculosis_H37Rv PEHTFTWETGLRLRAALNALGVRTALSRGNDNALGPCVDERANMANALRP
MMAR_5233|M.marinum_M PEHTFTWDTALRLRAALNALGVRTALSRGNDNALGPCIDERANTANALHP
MUL_4308|M.ulcerans_Agy99 PEHTFTWDTALRLRAALNALGVRTALSRGNDNALGPCIDERANTANALHP
MLBr_02331|M.leprae_Br4923 PEHTFTWDTALQVRAALDGLGVRTALSRGDDTGLGPCVDARANMANALHP
MAB_0318c|M.abscessus_ATCC_199 PEHTFTWNTVLLIRQQLTQLGVRTAMTRGDDNKLGPCIDKRAEIENSYNP
MAV_2168|M.avium_104 PEHVFTWAVVGLINASLNQMGVHTQLSRADDSGVGPCIDQRADAANAMRP
.** * * . :. * :**:* ::*.:*. ***:* ** *: *
Mflv_1286|M.gilvum_PYR-GCK NAVVSIHGDGGPATGRGFHVLYSSPPLNAAQAGPSVQFAKVMRDQLAGSG
Mvan_5529|M.vanbaalenii_PYR-1 NAVVSIHADGGPATGRGFHVLYSSPPLNAAQAGPSVQFAKVMRDQLAGSG
MSMEG_6281|M.smegmatis_MC2_155 HAIVSIHADGGPPTGRGFHVLYSSPPLNAAQSGPSVQFAKVMRDQLAASG
TH_2289|M.thermoresistible__bu DAIVSIHADGGPPTGRGFHVLYSSPPLNAVQAGPSVQFAKIMRDQLAASG
Mb3744|M.bovis_AF2122/97 NAIVSLHADGGPASGRGFHVNYSAPPLNAIQAGPSVQFARIMRDQLQASG
Rv3717|M.tuberculosis_H37Rv NAIVSLHADGGPASGRGFHVNYSAPPLNAIQAGPSVQFARIMRDQLQASG
MMAR_5233|M.marinum_M NAVVSLHGDGGPATGRGFHVNYSSPPLNAAQAGPSVQFARVMRDQLRASG
MUL_4308|M.ulcerans_Agy99 NAVVSLHGDGGPATGRGFHVNYSSPPLNAAQAGPSVQFARVMRDQLRASG
MLBr_02331|M.leprae_Br4923 NASVSLHGDGGPASGRGFHVIYSAPPLNPVQAGPSVQFARIMRDQLQASG
MAB_0318c|M.abscessus_ATCC_199 DAVVSIHADGGPAGGHGFHVNYSNPPVNAVQGEPTLRFAKTMRDSLQAAG
MAV_2168|M.avium_104 DAIVSIHADGGPASGSGFHVNYSSPPLNDVQAGPAVQLAHAMRDALAQAG
.* **:*.****. * **** ** **:* *. *::::*: *** * :*
Mflv_1286|M.gilvum_PYR-GCK IPPATYIGQQGLNPRSDIAGLNLAQYPSILVELGNMKSPVDSALMKSPEG
Mvan_5529|M.vanbaalenii_PYR-1 IPPATYIGQQGLNPRSDIAGLNLAQFPSILVELGNMKSPVDSALMKTPEG
MSMEG_6281|M.smegmatis_MC2_155 IPPATYIGQGGLNPRSDIAGLNLAQFPSVLVECGNMKNPVDSALMKSPEG
TH_2289|M.thermoresistible__bu IPPSTYIGSNGLNPRADIAGLNHAQYPAILVELGNMKNPVDSALMKAPEG
Mb3744|M.bovis_AF2122/97 IPKANYIGQDGLYGRSDLAGLNLAQYPSILVELGNMKNPADSALMESAEG
Rv3717|M.tuberculosis_H37Rv IPKANYIGQDGLYGRSDLAGLNLAQYPSILVELGNMKNPADSALMESAEG
MMAR_5233|M.marinum_M IPPANYIGQDGLYGRSDLAGLNLAQYPSILVELGNMKNPADSALMESPEG
MUL_4308|M.ulcerans_Agy99 IPPANYIGQDGLYGRSDLAGLNLAQYPSILVELGNMKNPADSALMESPEG
MLBr_02331|M.leprae_Br4923 IPPANYIGQSGLCGRSDLAGLNLAQYSSILIELGNMKNPADSALMESSEG
MAB_0318c|M.abscessus_ATCC_199 LTPATYIGTGGLYGRSDLAGLNLAQHPKVLVELGNMKNAQDSAMMTSPEG
MAV_2168|M.avium_104 FQPATYIGSDGLYGRDDLAGLNLAQYPAVLVELGNMKNAGDAARMESPDG
: :.*** ** * *:**** **.. :*:* ****.. *:* * :.:*
Mflv_1286|M.gilvum_PYR-GCK RQKYADAVVRGIVAFLSQA---------------
Mvan_5529|M.vanbaalenii_PYR-1 RQRYADAVVRGIVAFLSSQR--------------
MSMEG_6281|M.smegmatis_MC2_155 RQKYADAIVRGIAGFLGSQSQAAAAVSPVR----
TH_2289|M.thermoresistible__bu RQKYADAVVRGIAAFLSAQARVR-----------
Mb3744|M.bovis_AF2122/97 RQKYANALVRGVAGFLATQGQAR-----------
Rv3717|M.tuberculosis_H37Rv RQKYANALVRGVAGFLATQGQAR-----------
MMAR_5233|M.marinum_M RQKYANALVRGVAGFLASQGQAR-----------
MUL_4308|M.ulcerans_Agy99 RQKYANALVRGVAGFLASQGQAR-----------
MLBr_02331|M.leprae_Br4923 RKKYADAVVRGVEGFLATQSRAR-----------
MAB_0318c|M.abscessus_ATCC_199 RSKYAQAVVQGIVAYLSGTAPAAAPAPEAAPAGG
MAV_2168|M.avium_104 RAAYAAAVTAGIVAFLNAKAASG-----------
* ** *:. *: .:*