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M. thermoresistible (build 8) TH_2063 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 4039844 - 4041142
length: 433

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2063-100% (433)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_2821-4e-0925.91% (220) PUTATIVE magnesium transporter
M. thermoresistible (build 8)TH_2700-2e-0735.29% (102) PUTATIVE putative AAA ATPase containing von Willebrand factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1264c-1e-17373.41% (425) hypothetical protein Mb1264c
M. gilvum PYR-GCKMflv_2208-0.083.99% (431) MgtE intracellular region
M. tuberculosis H37RvRv1232c-1e-17373.41% (425) hypothetical protein Rv1232c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1524c-1e-18074.53% (424) hypothetical protein MAB_1524c
M. marinum MMMAR_4209-1e-17874.41% (426) transport transmembrane protein
M. avium 104MAV_1371-1e-17372.83% (427) Mg/Co/Ni transporter MgtE
M. smegmatis MC2 155MSMEG_5065-0.084.47% (425) Mg/Co/Ni transporter MgtE
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_4488-0.081.76% (433) MgtE intracellular region

CLUSTAL 2.0.9 multiple sequence alignment


TH_2063|M.thermoresistible__bu      MASVNRVYAARLAGMVVLGPDGESIGRVRDVVISISIVRQQPRVLGLVVE
MSMEG_5065|M.smegmatis_MC2_155      MAAVNRVYAARLAGLVVLGPDGESIGRVRDVVISISIVRQQPRVIGLVVE
Mflv_2208|M.gilvum_PYR-GCK          MASVNRVYAARLAGMVVLGPDGESIGRVRDVVIGISVVRHQPRVLGLVIE
Mvan_4488|M.vanbaalenii_PYR-1       MVSVNRVYAARLAGMVVLGPDGESIGRVRDVVIGISLVRHQPRVLGLVIE
MAB_1524c|M.abscessus_ATCC_199      MAAVSKVFAARLSGLVVLGPDGESIGRVRDVVIGMGVARKQPRVIGLVVE
Mb1264c|M.bovis_AF2122/97           MGSVNRVYLARLSRMSVLGPLGESFGRVRDVVISISIVRQQPRVLGLVVD
Rv1232c|M.tuberculosis_H37Rv        MGSVNRVYLARLSRMSVLGPLGESFGRVRDVVISISIVRQQPRVLGLVVD
MMAR_4209|M.marinum_M               MGSVNRVYVARLSRMMVLGPFGETFGRVRDVVISISIVRQQPRVLGLVVD
MAV_1371|M.avium_104                ------MYIARLARMLVLGPLGESVGRVRDVVISISIVRQQPRVLGLVVD
                                          :: ***: : **** **:.********.:.:.*:****:***::

TH_2063|M.thermoresistible__bu      LLTRRRIFVPILRVTAIEPGAVTLNTANVSLRRFAQRPGEVLVLGQVVET
MSMEG_5065|M.smegmatis_MC2_155      LLTRRRIFVPILRVTAIEPGAVTLATGSVSLRKFVQRPGEVLVLGQVLET
Mflv_2208|M.gilvum_PYR-GCK          LLSRRRIFVPILRVTAIEPGAVTLSTGNVSLRRFSQRPGEVLVLGQVVET
Mvan_4488|M.vanbaalenii_PYR-1       LMTRRRIFVPILRVTAIEPGAVTLSTGNVSLRRFSQRPGEVLVLGQVIET
MAB_1524c|M.abscessus_ATCC_199      MLTRRRIFVPMLRVTAIEPGSVTLNTGNVSLRRFEQRPSEALVLGQVLDT
Mb1264c|M.bovis_AF2122/97           LATRRKIFIPILRVAAIEPHAVTLSTGNVSLHRFEQRPGEALALGQVLDT
Rv1232c|M.tuberculosis_H37Rv        LATRRKIFIPILRVAAIEPHAVTLSTGNVSLHRFEQRPGEALALGQVLDT
MMAR_4209|M.marinum_M               LATRRSIFIPMLRVAAIEPNAVTLSTASVSLRHFEQRPGEVLAIGQVLDT
MAV_1371|M.avium_104                LATRRSIFIPILRVAAIDPNAVTLSTGSVSLRHFEQRPGEVLAIGQVLDT
                                    : :** **:*:***:**:* :*** *..***::* ***.*.*.:***::*

TH_2063|M.thermoresistible__bu      RVRINDPDLPDLAGVDLVVVDLGIEQSRTRDWLVTRVAVRRPHRRLTRRS
MSMEG_5065|M.smegmatis_MC2_155      RVRVEDPDLPELAGVDVVVVDLGIEQTRTRDWVVTRFAVRQ-QRRLGRRS
Mflv_2208|M.gilvum_PYR-GCK          RVRVDDPDLPALAGLDVVVVDLGIEQTRTRDWVVTRVAVRP-QRRLGRRS
Mvan_4488|M.vanbaalenii_PYR-1       RVRVDDPDLPQLAGVDVVVVDLAIEQTRARDWMVTKVAVRQ-QRRLGRRS
MAB_1524c|M.abscessus_ATCC_199      TVRTDDPELEQFHGVDLTVVDLGLEQTRTRDWVVTRVAVRS-PRRLGRRT
Mb1264c|M.bovis_AF2122/97           LVKVNDPALPELAGVDVVVTDLGVEQTRSRDWMVTRVAVRT-QRRLRRRG
Rv1232c|M.tuberculosis_H37Rv        LVKVNDPALPELAGVDVVVTDLGVEQTRSRDWMVTRVAVRT-QRRLRRRC
MMAR_4209|M.marinum_M               PVRVNDPDLPELANADIVITDLGIEQTRTRDWMVTRVAVRS-PRRLGRRG
MAV_1371|M.avium_104                VVKVNDPELPELAGVDVVVTDLGIEQTRTRDWMVTRVAVRP-QRRLRRRG
                                     *: :** *  : . *:.:.**.:**:*:***:**:.***   *** ** 

TH_2063|M.thermoresistible__bu      NIYVTDWQYVVQGLTPSGLALPDQGVAQLLEQFEGQRPVEVADALRELPP
MSMEG_5065|M.smegmatis_MC2_155      NVYVVEWQN-VHGLTPSGLAMPDQGVASLLEQFEGQRPVEVAEALRELPP
Mflv_2208|M.gilvum_PYR-GCK          NVYTTEWDH-VQGLTPAGLAMPDQGVAQLLEQFEGQRPVEVADAIRELPG
Mvan_4488|M.vanbaalenii_PYR-1       NVYTVEWQN-VQGLTPSGLAMPDQGVAQLLEQFEGQRAVEVADAIRELPN
MAB_1524c|M.abscessus_ATCC_199      GVQVTDWSH-IQGLTPSTLNLPGQGVAQLMLQFEGMRPVEVADAIRELPP
Mb1264c|M.bovis_AF2122/97           PVHVVDWHN-VAGLTPSALAMPGQDVAQLLDQFEGWKAVDVADAIRGLPP
Rv1232c|M.tuberculosis_H37Rv        PVHVVDWHN-VAGLTPSALAMPGQDVAQLLDQFEGWKAVDVADAIRGLPP
MMAR_4209|M.marinum_M               PLHVVDWQN-VRGLTPSALAMPDQDVAQLLDQFEGRRAVDVADAIRGLPS
MAV_1371|M.avium_104                PVHVVDWRN-VQGLTPSALALPGQAVAQLLEQFEGRKPVDVADAIRGLPP
                                     : ..:*   : ****: * :*.* **.*: **** :.*:**:*:* ** 

TH_2063|M.thermoresistible__bu      KRRFEVIAAFDDDRLADVLQELTAAEQTQVLRQLKTDRAATVLEAMDPDD
MSMEG_5065|M.smegmatis_MC2_155      KRRYELFRAFDDDRLADVLAELPEDEQADVLRGLNTERAALVLEAMDPDD
Mflv_2208|M.gilvum_PYR-GCK          KRRNEVVNALDDERLADVLQELPEEEQVELLRQLKTDRAADVLEAMDPDD
Mvan_4488|M.vanbaalenii_PYR-1       KRRYEVVNALDDERLADVLQELPEDQQVALLRQLKTDRAADVLEAMDPDD
MAB_1524c|M.abscessus_ATCC_199      KRRDEVLGAFDDERLADILQELPEDDQAEVLTKLEDERAADVLEAMDPDD
Mb1264c|M.bovis_AF2122/97           KRRHEVFKALHDKRLADVLQELPELDQAEVLSQLGTERAADVLEEMDPDD
Rv1232c|M.tuberculosis_H37Rv        KRRHEVFKALHDKRLADVLQELPELDQAEVLSQLGTERAADVLEEMDPDD
MMAR_4209|M.marinum_M               KRRYEVFKALDDERLADILQELPELDQAEVLSQLGTERAADVLEEMDPDD
MAV_1371|M.avium_104                KRRYEVLKALNDDRLADILQELPELDQAEVLSQLGTERSADVLEEMDPDD
                                    *** *:. *:.*.****:* **.  :*. :*  *  :*:* *** *****

TH_2063|M.thermoresistible__bu      AADLLGALAPTDAEALLRRMDPEDSEDVRRLLSHSPNTAGGLMTSEPVVL
MSMEG_5065|M.smegmatis_MC2_155      AADLLGAMTPADAEVLLGRMDPEDSEDVRRLLAHSPDTAGGLMTSEPVVL
Mflv_2208|M.gilvum_PYR-GCK          AADLLGTMTPADAEQLLRRMDPEDSEDVRRLLSHSPNTAGGLMTSEPVVL
Mvan_4488|M.vanbaalenii_PYR-1       AADLLGTMTPADAEQFLRRMDPEDSEDVRRLLSHSPDTAGGLMTSEPVVL
MAB_1524c|M.abscessus_ATCC_199      AADLLGELPPAEAESLLALMDPEDSEPVRRLLTHSPNTAGGMMTPEPVIL
Mb1264c|M.bovis_AF2122/97           AADLLAVLNPTEAELLLTRMDPGDSGQVRRLLTHSPDTAGGLMTSDPVVL
Rv1232c|M.tuberculosis_H37Rv        AADLLAVLNPTEAELLLTRMDPGDSGQVRRLLTHSPDTAGGLMTSDPVVL
MMAR_4209|M.marinum_M               AADLLGVLNPTDAEVLLTRMDPDDSDSVRRLLQHSPDTAGGLMTSNPVVL
MAV_1371|M.avium_104                AADLLGVLNPTDAEMLLKRMDPGDSASVRRLLTHSPDTAGGLMTSNPVVL
                                    *****. : *::** :*  *** **  ***** ***:****:**.:**:*

TH_2063|M.thermoresistible__bu      SPGTTVAEALARVRDPDLTPAVASVAFVTRPPTATPTGHYLGCVHLQRLL
MSMEG_5065|M.smegmatis_MC2_155      APDTTVAEALARVRDPDLTPALASLAFVARPPTATPTGHYLGCVHLQRLL
Mflv_2208|M.gilvum_PYR-GCK          APDTTVAEALARVRDPDLTPALASLVFVVRPPTATPTGHYLGCVHLQRLL
Mvan_4488|M.vanbaalenii_PYR-1       APDTTVAEALARVRDPDLTPALASVVFVVRPPTSTPTGRYLGCVHLQRLL
MAB_1524c|M.abscessus_ATCC_199      TPNTTVAEALARVRDPDLTPALSSLVFVVRPPTATPTGRYLGCVHLQRLL
Mb1264c|M.bovis_AF2122/97           TPDTSIAEALARVRDPDLTPALASMVFVARPPTATPTGHYLGCVHLQRLL
Rv1232c|M.tuberculosis_H37Rv        TPDTSIAEALARVRDPDLTPALASMVFVARPPTATPTGHYLGCVHLQRLL
MMAR_4209|M.marinum_M               TPDTSVAEALARVRDPDLTPALSSMVFVARPPTATPTGHYVGYVHLQRLL
MAV_1371|M.avium_104                TPDTAVAEALARARDPDLTAALSSMVFVVRPPTATPTGRYLGCVPLQRLL
                                    :*.*::******.******.*::*:.**.****:****:*:* * *****

TH_2063|M.thermoresistible__bu      REPPAALVSGILDADLPVLHPEESLAAVTRYFAAYNLVCGPVVDEQNHLL
MSMEG_5065|M.smegmatis_MC2_155      REPPATLVSGIVDNDLPTLSPEDSLAAVTRYFAAYNLVCGPVVDSQNHLV
Mflv_2208|M.gilvum_PYR-GCK          REPPATLVSGIIDSDLPQLAPEDSLGALTRYFAAYNLVCGPVVDEENHLL
Mvan_4488|M.vanbaalenii_PYR-1       REPPAGLVSGIVDTDLPSLRPEDSLGALTRYFAAYNLVCGPVVDEESHLL
MAB_1524c|M.abscessus_ATCC_199      REPPYAMVGGILDTDLPYLDAEAPLAEVTRYFAAYNLVCGPVIDREDHLL
Mb1264c|M.bovis_AF2122/97           RDPPAELVGGVVDTDLLTLTPETPLAAVTRYFAAYNLVCGPVVDDENHLL
Rv1232c|M.tuberculosis_H37Rv        RDPPAELVGGVVDTDLLTLTPETPLAAVTRYFAAYNLVCGPVVDDENHLL
MMAR_4209|M.marinum_M               REPPAELVGGIVDTDLLTLTPETPLAAVTRYFAAYNLVCGPVVDDQNHLL
MAV_1371|M.avium_104                REAPAELVGGIVDSDLLTLRPETPLVAVTRYLAAYNLVCGPVVDDENHLL
                                    *:.*  :*.*::* **  * .* .*  :***:**********:* :.**:

TH_2063|M.thermoresistible__bu      GAVSVDDVLDHLLPDDWRQQE-EPELTDAEGLT----
MSMEG_5065|M.smegmatis_MC2_155      GAVSVDDVLDHLLPDDWRETD-EPELRVSGS------
Mflv_2208|M.gilvum_PYR-GCK          GAVSVDDVLDHLLPDNWRERESEPLIVSVEGRHE---
Mvan_4488|M.vanbaalenii_PYR-1       GAVSVDDVLDHLLPDDWRDREAEPVIVTAEKAT----
MAB_1524c|M.abscessus_ATCC_199      GAVTVDDVLDHLMPDGWRAEE--PEAVAGGDRP----
Mb1264c|M.bovis_AF2122/97           GAVTVDDLLDHLLPHDWRVDMPELDPSGAPDRPGGPR
Rv1232c|M.tuberculosis_H37Rv        GAVTVDDLLDHLLPHDWRVDMPELDPSGAPDRPGGPR
MMAR_4209|M.marinum_M               GAVTVDDLLDHLLPHDWRVDVQQLDPAGRPARSGGAL
MAV_1371|M.avium_104                GAVTVDDLLDHLLPPDWRVDMQELDTAGRLEGLGGSG
                                    ***:***:****:* .**