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M. avium 104 MAV_1717 (-)

annotation: pyruvate synthase
coordinates: 1691598 - 1693568
length: 656

MEGNDVDPNGSGAGSDSQNGASPNGSSRQRLEQVVIRFAGDSGDGMQLTGDRFTSEAALFGNDLATQPNY
PAEIRAPAGTLPGVSSFQIQIADYDILTAGDRPDVLVAMNPAALKANIGDLPRGGMVIANSDEFTKRNLT
KVGYVTNPLETDELSDYVVHSVAMTTLTLGAVESIGASKKDGQRAKNMFALGLLSWMYGRPIETSEKFIR
EKFARKPEVAETNVLALKAGWNYGETTEAFGTTYEVSRATLPAGEYRQISGNTALAYGIVAAGQLADIPV
VLGSYPITPASDILHELSKHKNFNVITFQAEDEIGGICAAIGASYGGALGVTTTSGPGISLKSEALGLAV
MTELPLLVVDVQRGGPSTGLPTKTEQADLLQALFGRNGESPVAVLAPRSPSDCFETALEAARIAVSYHTP
VIVLSDGAIANGSEPWRIPDVSTLPRITHAFAKPDEPFQPYARDPETLARQFAVPGTPGLEHRIGGLEAA
NGSGNISYEPVNHDLMVRLRQAKIDGISVPDLEVDDPTGDAELLLIGWGSSYGPIGEACRRARRKGIKVA
HAHLRYLNPFPANLGEVLRRYPQVVCPEMNLGQLALLLRGKYLVDVQSVSKVQGVAFLADEIGRVIRAAL
GGTLAEVENDKTMVARMAAATVGASA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_1717--100% (656)pyruvate synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2482c-0.088.94% (651) oxidoreductase alpha subunit
M. gilvum PYR-GCKMflv_2616-0.084.48% (625) pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing
M. tuberculosis H37RvRv2455c-0.088.94% (651) oxidoreductase alpha subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1594-0.081.04% (633) ferredoxin oxidoreductase, alpha subunit
M. marinum MMMAR_3803porA0.088.75% (649) pyruvate:ferredoxin oxidoreductase, PorA, alpha subunit
M. smegmatis MC2 155MSMEG_4646-0.086.52% (638) pyruvate synthase
M. thermoresistible (build 8)TH_0354-0.084.34% (645) PROBABLE OXIDOREDUCTASE (ALPHA SUBUNIT)
M. ulcerans Agy99MUL_3726porA0.088.60% (649) pyruvate:ferredoxin oxidoreductase, PorA, alpha subunit
M. vanbaalenii PYR-1Mvan_3965-0.082.90% (655) pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2616|M.gilvum_PYR-GCK          ---------------------MASQATSAPRQKLEKVVIRFAGDSGDGMQ
Mvan_3965|M.vanbaalenii_PYR-1       MRPRQHPGENTEGRRVGENGNAAGNVTGAPRQKLEKVVIRFAGDSGDGMQ
MSMEG_4646|M.smegmatis_MC2_155      ------------------MGDNGNGTGAAPRQKLEKVVIRFAGDSGDGMQ
TH_0354|M.thermoresistible__bu      ----------MGPSGNGANPAEQVNGSGTSRKKLEKVVIRFAGDSGDGMQ
MAB_1594|M.abscessus_ATCC_1997      ------------------------MGDGAVSEKLEKVVIRFAGDSGDGMQ
Mb2482c|M.bovis_AF2122/97           --------MDPNGSGAGPESHDAAFHAAPDRQRLENVVIRFAGDSGDGMQ
Rv2455c|M.tuberculosis_H37Rv        --------MDPNGSGAGPESHDAAFHAAPDRQRLENVVIRFAGDSGDGMQ
MMAR_3803|M.marinum_M               --------MDPNGSEAGPESHTAATHGGPDRQRLENVVIRFAGDSGDGMQ
MUL_3726|M.ulcerans_Agy99           --------MDPNGSEAGPESHTAATHGGLDRQRLENVVIRFAGDSGDGMQ
MAV_1717|M.avium_104                ---MEGNDVDPNGSGAGSDSQNGASPNGSSRQRLEQVVIRFAGDSGDGMQ
                                                               .   ::**:**************

Mflv_2616|M.gilvum_PYR-GCK          LTGDRFTTEAALFGNDLATQPNYPAEIRAPQGTLPGVSSFQIQIADYDIL
Mvan_3965|M.vanbaalenii_PYR-1       LTGDRFTSEAALFGNDLATQPNYPAEIRAPQGTLPGVSSFQIQIADYDIL
MSMEG_4646|M.smegmatis_MC2_155      LTGDRFTSEAALFGNDLATQPNYPAEIRAPQGTLPGVSSFQIQIADYDIL
TH_0354|M.thermoresistible__bu      LTGDRFTSEAALFGNDLATQPNYPAEIRAPQGTLPGVSSFQIQIADYDIL
MAB_1594|M.abscessus_ATCC_1997      LTGDRFTSEAAIFGNDLATQPNYPAEIRAPQGTLPGVSSFQIQIADYDIL
Mb2482c|M.bovis_AF2122/97           LTGDRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDIL
Rv2455c|M.tuberculosis_H37Rv        LTGDRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDIL
MMAR_3803|M.marinum_M               LTGDRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDIL
MUL_3726|M.ulcerans_Agy99           LTGDRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDIL
MAV_1717|M.avium_104                LTGDRFTSEAALFGNDLATQPNYPAEIRAPAGTLPGVSSFQIQIADYDIL
                                    *******:***:****************** *******************

Mflv_2616|M.gilvum_PYR-GCK          TAGDRPDVLVAMNPAALKANVSDLPRGGLIIANSDEFTKRNLAKVGYDAN
Mvan_3965|M.vanbaalenii_PYR-1       TAGDRPDVLVAMNPAALKANVSDLPRGGLIIANSDEFTKRNLAKVGYDAN
MSMEG_4646|M.smegmatis_MC2_155      TAGDRPDVLVAMNPAALKANVSDLPRGGLIIANSDEFTKRNLAKVGYDAN
TH_0354|M.thermoresistible__bu      TAGDRPDVLVAMNPAALKANVGDLPHGGLIIANSDEFTKRNLAKVGYEAN
MAB_1594|M.abscessus_ATCC_1997      TAGDRPDVLVAMNPAALKANIGDLPRGGMVIANSDEFTKRNLAKVGYQSD
Mb2482c|M.bovis_AF2122/97           TAGDRPDVLVAMNPAALKANIGDLPLGGMVIVNSDEFTKRNLTKVGYVTN
Rv2455c|M.tuberculosis_H37Rv        TAGDRPDVLVAMNPAALKANIGDLPLGGMVIVNSDEFTKRNLTKVGYVTN
MMAR_3803|M.marinum_M               TAGDRPDVLVAMNPAALKANIGDLPLGGMVIANSDEFTKRNLTKVGYVTN
MUL_3726|M.ulcerans_Agy99           TAGDRPDVLVAMNPAALKANIGDLPLGGMVIANSDEFTKRNLTKVGYVTN
MAV_1717|M.avium_104                TAGDRPDVLVAMNPAALKANIGDLPRGGMVIANSDEFTKRNLTKVGYVTN
                                    ********************:.*** **::*.**********:**** ::

Mflv_2616|M.gilvum_PYR-GCK          PLESDELSDYVVQAVPMTTLTLGAVEEIGATKKDGQRAKNMFALGLLSWM
Mvan_3965|M.vanbaalenii_PYR-1       PLESEELSDYVVQAVPMTTLTLGAVESIGATKKDGQRAKNMFALGLLSWM
MSMEG_4646|M.smegmatis_MC2_155      PLETDELSDYVVHSVAMTTLTLGAVESIGASKKDGQRAKNMFALGLLSWM
TH_0354|M.thermoresistible__bu      PLETDELSDYVVHAVPMTTLTLGAVESIGATKKDGQRAKNMFALGLLSWM
MAB_1594|M.abscessus_ATCC_1997      PLEHDDMSDYVVYQVPMTTLALGAVEPAGVSKKDGARTKNMFALGLLSWM
Mb2482c|M.bovis_AF2122/97           PLESGELSDYVVHTVAMTTLTLGAVEAIGASKKDGQRAKNMFALGLLSWM
Rv2455c|M.tuberculosis_H37Rv        PLESGELSDYVVHTVAMTTLTLGAVEAIGASKKDGQRAKNMFALGLLSWM
MMAR_3803|M.marinum_M               PLESDELEEYVVHSVPMTTLTLGAVEAIGASKKDGQRAKNMFALGLVSWM
MUL_3726|M.ulcerans_Agy99           PLESDELEEYVVHSVPMTTLTLGAVEAIGASKKDGQRAKNMFALGLVSWM
MAV_1717|M.avium_104                PLETDELSDYVVHSVAMTTLTLGAVESIGASKKDGQRAKNMFALGLLSWM
                                    ***  ::.:***  *.****:*****  *.:**** *:********:***

Mflv_2616|M.gilvum_PYR-GCK          YGRELEHSEAFIREKFARKPDVAEANVLALKAGWNFGETTEAFAITYEVA
Mvan_3965|M.vanbaalenii_PYR-1       YGRELEHSESFIREKFARKPDVAEANVLALKAGWNYGETTEAFGTTYEVS
MSMEG_4646|M.smegmatis_MC2_155      YGRELEASEAFIREKFARKPEIAEANVLALKAGWNYGETTEAFATTYEVS
TH_0354|M.thermoresistible__bu      YGRELDHSVAFIREKFARKPEIAEANVLALKAGWNYGETTEAFATTYEVA
MAB_1594|M.abscessus_ATCC_1997      YHRPLEGTEQFLREKFAKKPDVAEANILAFRAGWNYGETTEAFGTTYEVA
Mb2482c|M.bovis_AF2122/97           YGRELEHSEAFIREKFARKPEIAEANVLALKAGWNYGETTEAFGTTYEIP
Rv2455c|M.tuberculosis_H37Rv        YGRELEHSEAFIREKFARKPEIAEANVLALKAGWNYGETTEAFGTTYEIP
MMAR_3803|M.marinum_M               YGRPIQTSETFIREKFARKPEIAEANVLALKAGWNFGETTEAFGTTYEVP
MUL_3726|M.ulcerans_Agy99           YGRPIQTSETFIREKFARKPEIAEANVLALKAGWNFGETTEAFGTTYEVP
MAV_1717|M.avium_104                YGRPIETSEKFIREKFARKPEVAETNVLALKAGWNYGETTEAFGTTYEVS
                                    * * :: :  *:*****:**::**:*:**::****:*******. ***:.

Mflv_2616|M.gilvum_PYR-GCK          PAKLKTGEYRQISGNTALAYGIVAAGQLSDLQVVLGTYPITPASDILHEL
Mvan_3965|M.vanbaalenii_PYR-1       PAKLQTGEYRQISGNTALAYGIVTAGQLADLQVVLGTYPITPASDILHEL
MSMEG_4646|M.smegmatis_MC2_155      PAKLPAGEYRQISGNTALAYGIVAAGHLSDLQVVLGTYPITPASDILHEL
TH_0354|M.thermoresistible__bu      PAKLKSGEYRQISGNTALAYGIVAAGHLANLQVILGTYPITPASDILHEL
MAB_1594|M.abscessus_ATCC_1997      KASLPAGEYRQVSGNTAMAYGVVAAGRLANTKVVLGTYPITPASDILHEL
Mb2482c|M.bovis_AF2122/97           PATLPPGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHEL
Rv2455c|M.tuberculosis_H37Rv        PATLPPGEYRQISGNTALAYGIVVAGQLAGLPVVLGSYPITPASDILHEL
MMAR_3803|M.marinum_M               PAKLPPGDYRQISGNTALAYGIVAAGQLADLPVVLGSYPITPASDILHEL
MUL_3726|M.ulcerans_Agy99           PAKLPPGDYRQISGNTALAYGIVAAGQLADLPVVLGSYPITPASDILHEL
MAV_1717|M.avium_104                RATLPAGEYRQISGNTALAYGIVAAGQLADIPVVLGSYPITPASDILHEL
                                     *.* .*:***:*****:***:*.**:*:.  *:**:*************

Mflv_2616|M.gilvum_PYR-GCK          SKHKNFNVMTFQAEDEIAGIGAAIGASYGGALGVTSTSGPGISLKSEAIG
Mvan_3965|M.vanbaalenii_PYR-1       SKHKNFNVLTFQAEDEIAGIGAAIGASYGGALGVTSTSGPGVSLKSEAIG
MSMEG_4646|M.smegmatis_MC2_155      SKHKNFNVLTFQAEDEIAGIGAAIGASYGGALGVTSTSGPGVSLKSEAIG
TH_0354|M.thermoresistible__bu      SKHKNFNVLTFQAEDEIAGIGAAIGASYGGALGVTSTSGPGVSLKSEAMG
MAB_1594|M.abscessus_ATCC_1997      SKYKNFDVLTFQAEDEIAGIGAALGASFGGALGVTSTSGPGVALKSEAVG
Mb2482c|M.bovis_AF2122/97           SKHKNFNVVTFQAEDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALG
Rv2455c|M.tuberculosis_H37Rv        SKHKNFNVVTFQAEDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALG
MMAR_3803|M.marinum_M               SKHKNFNVTTFQAEDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALG
MUL_3726|M.ulcerans_Agy99           SKHKNFNVTTFQAEDEIGGICAALGAAYGGALGVTSTSGPGISLKSEALG
MAV_1717|M.avium_104                SKHKNFNVITFQAEDEIGGICAAIGASYGGALGVTTTSGPGISLKSEALG
                                    **:***:* ********.** **:**::*******:*****::*****:*

Mflv_2616|M.gilvum_PYR-GCK          LAVMTELPLLIIDVQRGGPSTGLPTKTEQADLLQAMFGRNGESPVALLAP
Mvan_3965|M.vanbaalenii_PYR-1       LAVMTELPLIVIDVQRGGPSTGLPTKTEQADLLQAMFGRNGESPLAVLAP
MSMEG_4646|M.smegmatis_MC2_155      LAVMTELPLIVIDVQRGGPSTGLPTKTEQADLLQALFGRNGESPVAVVAP
TH_0354|M.thermoresistible__bu      LAVMTELPLIVIDVQRGGPSTGLPTKTEQADLLQTMFGRNGESPVAVLAP
MAB_1594|M.abscessus_ATCC_1997      LAVMTELPLLVIDVQRGGPSTGLPTKTEQADLLQALYGRNGESPIAVLAP
Mb2482c|M.bovis_AF2122/97           LGVMTELPLLVIDVQRGGPSTGLPTKTEQADLLQALYGRNGESPVAVLAP
Rv2455c|M.tuberculosis_H37Rv        LGVMTELPLLVIDVQRGGPSTGLPTKTEQADLLQALYGRNGESPVAVLAP
MMAR_3803|M.marinum_M               LGVMTELPLIVIDVQRGGPSTGLPTKTEQADLLQALYGRNGESPLAVLAP
MUL_3726|M.ulcerans_Agy99           LGVMTELPLIVIGVQRGGPSTGLPTKTEQADLLQALYGRNGESPLAVLAP
MAV_1717|M.avium_104                LAVMTELPLLVVDVQRGGPSTGLPTKTEQADLLQALFGRNGESPVAVLAP
                                    *.*******:::.*********************:::*******:*::**

Mflv_2616|M.gilvum_PYR-GCK          RSPSDCFDIAVEAVRIAINYHTPVMILSDGAIANGSEPWAIPDISTYEPI
Mvan_3965|M.vanbaalenii_PYR-1       RSPSDCFDIAVEAARIAINYHTPVMILSDGAIANGSEPWRIPDVSGYAPI
MSMEG_4646|M.smegmatis_MC2_155      RSPSDCFDIAVEAARIAINYHTPVIILSDGAVANGSEPWRIPDITTYPRI
TH_0354|M.thermoresistible__bu      RSPSDCFDIAVEAARIAVTYHTPVVILSDGAIANGSEPWRIPDIASYPPI
MAB_1594|M.abscessus_ATCC_1997      RSPSDCFDIAIEAVRIALTYRTPVMILSDGAIANGSEPWAIPDIASYPAI
Mb2482c|M.bovis_AF2122/97           RSPADCFETALEAVRIAVSYHTPVILLSDGAIANGSEPWRIPDVNALPPI
Rv2455c|M.tuberculosis_H37Rv        RSPADCFETALEAVRIAVSYHTPVILLSDGAIANGSEPWRIPDVNALPPI
MMAR_3803|M.marinum_M               RSPADCFETALEAVRIAVSYHTPVILLSDGAIANGSEPWRIPNVADLAPI
MUL_3726|M.ulcerans_Agy99           RSPADCFETALEAVRIAVSYHTPVILLSDGAIANGSEPWRIPNVADLAPI
MAV_1717|M.avium_104                RSPSDCFETALEAARIAVSYHTPVIVLSDGAIANGSEPWRIPDVSTLPRI
                                    ***:***: *:**.***:.*:***::*****:******* **::     *

Mflv_2616|M.gilvum_PYR-GCK          EHTFAKEGEPFQPYARDPETLARQFAVPGTPGLAHRIGGLESANGSGNIS
Mvan_3965|M.vanbaalenii_PYR-1       EHTFAKEGEPFQPYARDPETLARQFAVPGTPGLAHRIGGLESANGSGNIS
MSMEG_4646|M.smegmatis_MC2_155      EHTFAKAGEPFQPYARDPETLARQFAIPGTPGLEHRIGGLESANGSGNIS
TH_0354|M.thermoresistible__bu      ESAFAKAGEPFAPYARDPETLARQFAIPGTPGLEHRIGGLEKANGSGNIS
MAB_1594|M.abscessus_ATCC_1997      QHTFASPDQDFAPYNRDPETLARQFAVPGTPGLEHRIGGLEKANGSGNIS
Mb2482c|M.bovis_AF2122/97           KHTFAKPGEPFQPYARDRETLARQFAIPGTPGLEHRIGGLEAANGSGDIS
Rv2455c|M.tuberculosis_H37Rv        KHTFAKPGEPFQPYARDRETLARQFAIPGTPGLEHRIGGLEAANGSGDIS
MMAR_3803|M.marinum_M               KHTFAKPDEPFQPYARDPETLARQFAVPGTPGLEHRIGGLEAANGTGAIS
MUL_3726|M.ulcerans_Agy99           KHTFAKPDEPFQPYARDPETLARQFAVPGTPGLEHRIGGLEAANGTGAIS
MAV_1717|M.avium_104                THAFAKPDEPFQPYARDPETLARQFAVPGTPGLEHRIGGLEAANGSGNIS
                                      :**. .: * ** ** ********:****** ******* ***:* **

Mflv_2616|M.gilvum_PYR-GCK          YEPKNHDLMVRLRQEKIAGITVPDLEVDDPTGDAELLLLGWGSSYGPIGE
Mvan_3965|M.vanbaalenii_PYR-1       YEPKNHDLMVRLRNEKIAGITVPDLEVDDPSGEAELLMLGWGSSYGPIGE
MSMEG_4646|M.smegmatis_MC2_155      YEPKNHDLMVRLRQEKIAGVTVPDLEVDDPTGDAELLMLGWGSSYGPIGE
TH_0354|M.thermoresistible__bu      YEPKNHDLMVRLRQEKIDGIKVPDLEVDDPTGDAELLMLGWGSSYGPIGE
MAB_1594|M.abscessus_ATCC_1997      YDPANHDLMVRLRQLKIDGITVPDLEVDDPTGDAQLLMIGWGSSYGPIGE
Mb2482c|M.bovis_AF2122/97           YEPTNHDLMVRLRQAKIDGIHVPDLEVDDPTGDAELLLIGWGSSYGPIGE
Rv2455c|M.tuberculosis_H37Rv        YEPTNHDLMVRLRQAKIDGIHVPDLEVDDPTGDAELLLIGWGSSYGPIGE
MMAR_3803|M.marinum_M               YEPTNHDLMVRLRQAKIEGISVPDLEVDDPTGDAELLIIGWGSSYGPIGE
MUL_3726|M.ulcerans_Agy99           YEPTNHDLMVRLRQAKIEGISVPDLEVDDPTGDAELLIIGWGSSYGPIGE
MAV_1717|M.avium_104                YEPVNHDLMVRLRQAKIDGISVPDLEVDDPTGDAELLLIGWGSSYGPIGE
                                    *:* *********: ** *: *********:*:*:**::***********

Mflv_2616|M.gilvum_PYR-GCK          ACRRARRKGIKVAHAQVRHLNPFPANLGDVLNKYAKVVVPEMNLGQLALL
Mvan_3965|M.vanbaalenii_PYR-1       ACRRARRNGIKVAHAQLRHLNPFPANLGEVLARYRKVVVPEMNLGQLALL
MSMEG_4646|M.smegmatis_MC2_155      ACRRARRKGIKVAQAHLRHLNPFPANLGEVLARYPKVVVPEMNLGQLALL
TH_0354|M.thermoresistible__bu      ACRRARQRGIKVAQAHLRHLNPFPANLGEVLRRYPKVVLPEMNLGQLALL
MAB_1594|M.abscessus_ATCC_1997      ACRRARRKGLKVAHAHLRHLNPFPQNLGEVLRKYPKVVAPEMNMGQLSLL
Mb2482c|M.bovis_AF2122/97           ACRRARRRGTKVAHAHLRYLNPFPANLGEVLRRYPKVVAPELNLGQLAQV
Rv2455c|M.tuberculosis_H37Rv        ACRRARRRGTKVAHAHLRYLNPFPANLGEVLRRYPKVVAPELNLGQLAQV
MMAR_3803|M.marinum_M               ACRRARRRGTKVAHAHLRYLNPFPANLGEVLRRYPQVVAPEMNLGQLALV
MUL_3726|M.ulcerans_Agy99           ACRRARRRGTKVAHAHLRYLNPFPANLGEVLRRYPQVVAPEMNLGQLALV
MAV_1717|M.avium_104                ACRRARRKGIKVAHAHLRYLNPFPANLGEVLRRYPQVVCPEMNLGQLALL
                                    ******:.* ***:*::*:***** ***:** :* :** **:*:***: :

Mflv_2616|M.gilvum_PYR-GCK          LRGRYLVDVQSVTKVEGMAFLADEVEGIIDSALDGTLGDKEIEKAKFARL
Mvan_3965|M.vanbaalenii_PYR-1       LRGKYLIDVQSVTKVEGMAFLADEVEGIIDAALEGTLGEKEIEKAKFARL
MSMEG_4646|M.smegmatis_MC2_155      LRGRFLVDVQSVTKVEGMAFLADEIEGIIDAALEGTLAEKENDKAKFARL
TH_0354|M.thermoresistible__bu      LRGKYLVDVQSVTKVEGMAFLADEVESIIDAALDGTLREKETDKAKLARA
MAB_1594|M.abscessus_ATCC_1997      LRGKYLVDVQSVTKVQGMAFLADEVEEIIDAALDGSLAEKESQKAVLARE
Mb2482c|M.bovis_AF2122/97           LRGKYLVDVQSVTKVKGVSFLADEIGRFIRAALAGRLAELEQDKTLVARL
Rv2455c|M.tuberculosis_H37Rv        LRGKYLVDVQSVTKVKGVSFLADEIGRFIRAALAGRLAELEQDKTLVARL
MMAR_3803|M.marinum_M               LRGKYLVDVQSVTKVKGVSFLADEVGRFIRAALAGRLGELEQDKMMVAKL
MUL_3726|M.ulcerans_Agy99           LRGKYLVDVQSVTKVKGVSFLADEVGRFIRAALAGRLGELEQDKMMVAKL
MAV_1717|M.avium_104                LRGKYLVDVQSVSKVQGVAFLADEIGRVIRAALGGTLAEVENDKTMVARM
                                    ***::*:*****:**:*::*****:  .* :** * * : * :*  .*: 

Mflv_2616|M.gilvum_PYR-GCK          AAATVEG-------VGVSA
Mvan_3965|M.vanbaalenii_PYR-1       AAATIEAPASEATGVGANA
MSMEG_4646|M.smegmatis_MC2_155      AAATVEGEANEESAVGANA
TH_0354|M.thermoresistible__bu      AAATVDTG------VGANA
MAB_1594|M.abscessus_ATCC_1997      SAVAVGDRA----------
Mb2482c|M.bovis_AF2122/97           SAATAGAGANG--------
Rv2455c|M.tuberculosis_H37Rv        SAATAGAGANG--------
MMAR_3803|M.marinum_M               SAATVEAGVGA--------
MUL_3726|M.ulcerans_Agy99           SAATVEAGVGA--------
MAV_1717|M.avium_104                AAATVGASA----------
                                    :*.: