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EDRPLTRRRRIRFGRNEKGLGRMTKVHKLIAGSLLVGSLAGGLGLGAGRAAADPPPPPPMPPPPPLVWAP PTPESEPPEAPPAAELPPPPSG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0649 | - | - | 100% (93) | hypothetical protein MAV_0649 |
| M. avium 104 | MAV_1722 | - | 3e-08 | 53.33% (45) | secreted protein |
| M. avium 104 | MAV_1247 | - | 2e-07 | 54.35% (46) | hypothetical protein MAV_1247 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3906 | - | 5e-08 | 55.00% (40) | hypothetical protein Mb3906 |
| M. gilvum PYR-GCK | Mflv_4819 | - | 5e-10 | 40.45% (89) | hypothetical protein Mflv_4819 |
| M. tuberculosis H37Rv | Rv3876 | - | 5e-08 | 55.00% (40) | hypothetical protein Rv3876 |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 3e-05 | 50.00% (42) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_4537c | - | 5e-10 | 49.18% (61) | hypothetical protein MAB_4537c |
| M. marinum M | MMAR_5107 | - | 5e-08 | 36.56% (93) | transmembrane protein rich in alanine, arginine and proline |
| M. smegmatis MC2 155 | MSMEG_5916 | - | 3e-08 | 42.25% (71) | hypothetical protein MSMEG_5916 |
| M. thermoresistible (build 8) | TH_4048 | - | 7e-07 | 34.44% (90) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4186 | - | 2e-07 | 35.48% (93) | transmembrane protein rich in alanine, arginine and proline |
| M. vanbaalenii PYR-1 | Mvan_5366 | - | 7e-08 | 51.06% (47) | hypothetical protein Mvan_5366 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4819|M.gilvum_PYR-GCK ----------------------MRWLRILPAKAHCLLRPDAVQMSRGPAS
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
Rv3876|M.tuberculosis_H37Rv MAADYDKLFRPHEGMEAPDDMAAQPFFDPSASFPPAPASANLPKPNGQTP
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5107|M.marinum_M MTVLSRGARVRRGGRRPGWVLLTTLLVLAIGASSALVFTNRVELLKLAVV
MUL_4186|M.ulcerans_Agy99 MTVLSRGARVRRGGRRPGWVLLTTLLVLAIGASSALVFTNRVELLKLAVV
Mvan_5366|M.vanbaalenii_PYR-1 MTDPTRGARLRRGGRRPGWILMTVLLVLAIAASSALVFTNRVELLKLAVI
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK RALYSKSACRCAGTYWAVGPRAVRVG-----------CHNHHSCLRISGV
MSMEG_5916|M.smegmatis_MC2_155 ----------------------------------------------MGGA
Mb3906|M.bovis_AF2122/97 PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
Rv3876|M.tuberculosis_H37Rv PPTSDDLSERFVSAPPPPPPPPPPPPPTPMPIAAGEPPSPEPAASKPPTP
MAV_0649|M.avium_104 ------------------------------------------------ME
MAB_4537c|M.abscessus_ATCC_199 ------------------------------------------------ML
MMAR_5107|M.marinum_M LALWAAVAGAFVSVLYRRQAEADQARARDMKLVYDLQLDREISARREYEL
MUL_4186|M.ulcerans_Agy99 LALWAAVAGAFVSVLYRRQAEADQARARDMKLVYDLQLDREISARREYEL
Mvan_5366|M.vanbaalenii_PYR-1 LALWAAVVAAFVSVIYRRQSDADQAKVRDLKLVYDLQLDREISARREYEL
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 ---------------------------------------------MTDQP
Mflv_4819|M.gilvum_PYR-GCK ALRGSVIVASAAMFVAGALGVAPAGHAAVCGSVGGVHVDVSGCA------
MSMEG_5916|M.smegmatis_MC2_155 LFAG----ATGAAALAGAQ---PAGDSAPMSVLG----PVPAFP------
Mb3906|M.bovis_AF2122/97 PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
Rv3876|M.tuberculosis_H37Rv PMPIAGPEPAPPKPPTPPMPIAGPEPAPPKPPTPPMPIAGPAPTPTESQL
MAV_0649|M.avium_104 DRPLTRRRRIRFGRNEKGLGRMTKVHKLIAGSLLVGSLAGGLGL------
MAB_4537c|M.abscessus_ATCC_199 VLTRWFRRALVSGVCVAGLLGAGVVPALADPGDPPDPGIEEPGP------
MMAR_5107|M.marinum_M AVESQLRRELAAELRGAAADEVAALRAELASLRTSLGILFDADL------
MUL_4186|M.ulcerans_Agy99 AVESQLRRELAAELRGAAADEVAALRAELASLRTSLGILFDADV------
Mvan_5366|M.vanbaalenii_PYR-1 AVETHLRRELASELRAQSADEVAALRAELAALRANLEFLFDTDL------
TH_4048|M.thermoresistible__bu -MESPVPMESPAPVTAAAHPRPAGERRRRLTVTG-----VVQGV------
MLBr_02395|M.leprae_Br4923 PPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGS------
Mflv_4819|M.gilvum_PYR-GCK -------------------DPLYELNDALAPP------------------
MSMEG_5916|M.smegmatis_MC2_155 -------------------PPPPPPPPFWGPP------------------
Mb3906|M.bovis_AF2122/97 APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
Rv3876|M.tuberculosis_H37Rv APPRPPTPQTPTGAPQQPESPAPHVPSHGPHQPRRTAPAPPWAKMPIGEP
MAV_0649|M.avium_104 -------------------GAG---RAAADPP------------------
MAB_4537c|M.abscessus_ATCC_199 -------------------PPPPPLPWELPPP------------------
MMAR_5107|M.marinum_M -------------------EQRPALETVDRESRTARAVADRLQNGESPAT
MUL_4186|M.ulcerans_Agy99 -------------------EQRPALETVDRESRTARAVADRLQNGESPAT
Mvan_5366|M.vanbaalenii_PYR-1 -------------------SHRPAIETERTAGRVSSSRIDTQEDFRAAEE
TH_4048|M.thermoresistible__bu -------------------GFRPFVHRLATELNLTG--------------
MLBr_02395|M.leprae_Br4923 ------------------YPPPPPPGGSYPPPPPPGG-------------
Mflv_4819|M.gilvum_PYR-GCK PPPPPPPPPPPGAPPP----------------------------------
MSMEG_5916|M.smegmatis_MC2_155 PPPPPPP--PFWRPPP----------------------------------
Mb3906|M.bovis_AF2122/97 PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
Rv3876|M.tuberculosis_H37Rv PPAPSRPSASPAEPPTRPAPQHSRRARRGHRYRTDTERNVGKVATGPSIQ
MAV_0649|M.avium_104 PPPPMPPPPPLVWAPP----------------------------------
MAB_4537c|M.abscessus_ATCC_199 PPPPAPDAPPPAEVPP----------------------------------
MMAR_5107|M.marinum_M DWLP-SDRIAMARRDENLNRAEEAIIDVPEVG---------------VPP
MUL_4186|M.ulcerans_Agy99 DWLP-SDRIAMARRDENLNRAEEAIIDVPEVG---------------VPP
Mvan_5366|M.vanbaalenii_PYR-1 PYAPKTDESPIIDVPAEPHPPEGEWAPRGEAGGAHRR----------SAE
TH_4048|M.thermoresistible__bu -FVGNDSGSVFIEVQG----------------------------------
MLBr_02395|M.leprae_Br4923 SYPPPPPSTGAYAPPP----------------------------------
Mflv_4819|M.gilvum_PYR-GCK -------PPP---PPPPPPPPVYIPPPLPNVNVCADVGRRINVSGCI---
MSMEG_5916|M.smegmatis_MC2_155 -------PPPIWLPPPPPPPPFWGPPPPP-----RPPGHWR---------
Mb3906|M.bovis_AF2122/97 ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
Rv3876|M.tuberculosis_H37Rv ARLRAEEASGAQLAPGTEPSPAPLGQPRSYLAPPTRPAPTEPPPSPSPQR
MAV_0649|M.avium_104 ------TPE----SEPPEAPPAAELPPPPSG-------------------
MAB_4537c|M.abscessus_ATCC_199 ------VPAPVPTTPPPGAPPTGDVPPLPVGLLKNSPNNGDVVGVAQPIT
MMAR_5107|M.marinum_M LDERDVQPGGGPFLQPPPPAPPGPEHPAEWVGPPQEAAP---VQPD----
MUL_4186|M.ulcerans_Agy99 LDERDVQPGRGPFLQPPPPAPPGPEHPAEWVGPPQEAAP---VQPD----
Mvan_5366|M.vanbaalenii_PYR-1 QPQWAPPPAPAPPPPPPPPPPPPPPPPAQQPPPPPQPTPPPAQQPSPEPQ
TH_4048|M.thermoresistible__bu -------PAGXX--XEPPPSPPSSEPPPSSEPPPTSAAP-----------
MLBr_02395|M.leprae_Br4923 -------PGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGMLIQTL
. . .
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
Rv3876|M.tuberculosis_H37Rv NSGRRAERRVHPDLAAQHAAAQPDSITAATTGGRRRKRAAPDLDATQKSL
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 IVFAAPVTDKKAAEAAVKITTSKPAPGYFYWYTDQQLRWKPTQFWPANTD
MMAR_5107|M.marinum_M ---LHYEPHRRPPPAPPVPNAEPSPWRPVAADGQWLPPGAPGSHWVAEEA
MUL_4186|M.ulcerans_Agy99 ---LHYEPHRRPPPAPPVPNAEPPLWRPVAADGQWLPPGAPGSHWVAEEA
Mvan_5366|M.vanbaalenii_PYR-1 FPWLPPAPPPRPQPRTPEPAPTASGWKPVPAEGQWIPAGEPGSHWAAAHA
TH_4048|M.thermoresistible__bu ----TANPAPQPEP-EPQPEPEPE------------PEPDPEEEPTAE--
MLBr_02395|M.leprae_Br4923 TKQEACVTDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQ
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
Rv3876|M.tuberculosis_H37Rv RPAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDEK
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 VNVNAGGTKWSFKVGDAFVSTVDDATYT--------MTVTRNGVVERTMP
MMAR_5107|M.marinum_M AGAETQDRSSGRRR--------RARHYG--------SDEGQGDIGEFDRE
MUL_4186|M.ulcerans_Agy99 AGAETQDRSSGRRR--------RARHYD--------SDEDQGDIGEFDRE
Mvan_5366|M.vanbaalenii_PYR-1 NGDQGE--YVGRRR--------APDQVE--------PEP-----------
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 GATGSSIGKTVMKFKVISEATGQPIGFG----------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
Rv3876|M.tuberculosis_H37Rv YELDLHARVRRNPRGSYQIAVVGLKGGAGKTTLTAALGSTLAQVRADRIL
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 ISMGKHDKKHETKNGTYYVSEKFQKMVMDSSTYGVPVNSAEGYKLDVYWA
MMAR_5107|M.marinum_M YGGRRSRSRHSTDYRDYGVGRLGAGPPPGPGPAQPPPMAPAAPPWPGPQP
MUL_4186|M.ulcerans_Agy99 YGGRRSRSRHSTDYRDYGVGRLGAGPPPGPGPAQPPPMASAAPPWPGPQP
Mvan_5366|M.vanbaalenii_PYR-1 -----PRGKHSAAG-------------------EEPTEAPAAP----EAP
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 -MSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKIMTTVCLPI-----
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
Rv3876|M.tuberculosis_H37Rv ALDADPGAGNLADRVGRQSGATIADVLAEKELSHYNDIRAHTSVNAVNLE
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 TRLSNSGIFVHAAPWSVGAQGKSDTSHGCINVNTDNATWFFNQSHPGDPV
MMAR_5107|M.marinum_M AEPAAPRLAPPPAPDLASRHRRPEEERPDVAGSHDSDSQSGGQSVADLMA
MUL_4186|M.ulcerans_Agy99 AEPAAPRLAPPPAPDLASRHRRPEEERPDVAGSHDSDSQSGGQSVADLMA
Mvan_5366|M.vanbaalenii_PYR-1 AEPDA-----------------------------DGGAHTGGQSVAELLA
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
Rv3876|M.tuberculosis_H37Rv VLPAPEYSSAQRALSDADWHFIADPASRFYNLVLADCGAGFFDPLTRGVL
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 IVKNSPGGPYKDYDGYDDWQRF----------------------------
MMAR_5107|M.marinum_M RLQVQPSGGGRRRRRDG---------------------------------
MUL_4186|M.ulcerans_Agy99 RLQVQPSGGGRRRRRDG---------------------------------
Mvan_5366|M.vanbaalenii_PYR-1 RLQAAPSGGGRRRRRED---------------------------------
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
Rv3876|M.tuberculosis_H37Rv STVSGVVVVASVSIDGAQQASVALDWLRNNGYQDLASRACVVINHIMPGE
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5107|M.marinum_M --------------------------------------------------
MUL_4186|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5366|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_5916|M.smegmatis_MC2_155 --------------------------------------------------
Mb3906|M.bovis_AF2122/97 PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
Rv3876|M.tuberculosis_H37Rv PNVAVKDLVRHFEQQVQPGRVVVMPWDRHIAAGTEISLDLLDPIYKRKVL
MAV_0649|M.avium_104 --------------------------------------------------
MAB_4537c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_5107|M.marinum_M --------------------------------------------------
MUL_4186|M.ulcerans_Agy99 --------------------------------------------------
Mvan_5366|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4048|M.thermoresistible__bu --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
Mflv_4819|M.gilvum_PYR-GCK ----------------
MSMEG_5916|M.smegmatis_MC2_155 ----------------
Mb3906|M.bovis_AF2122/97 ELAAALSDDFERAGRR
Rv3876|M.tuberculosis_H37Rv ELAAALSDDFERAGRR
MAV_0649|M.avium_104 ----------------
MAB_4537c|M.abscessus_ATCC_199 ----------------
MMAR_5107|M.marinum_M ----------------
MUL_4186|M.ulcerans_Agy99 ----------------
Mvan_5366|M.vanbaalenii_PYR-1 ----------------
TH_4048|M.thermoresistible__bu ----------------
MLBr_02395|M.leprae_Br4923 ----------------