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RIHDVRTRRSAEDFPRSEHLAWKIAEVAADPVAVPAETEAMVINRVIDNAAVSAASVLRRPVTVARAQAQ AHPAAAKGAKVFGIRGDYSPEWAAWANGVAVRELDFHDTFLAAEYSHPGDNIPALVAVAQHVGVGGADLI RGIATGYEIQIDLARGICLHEHKIDHVAHLGPSVAAGLGTMLRLDPETIYQAIGQALHLTTSTRQSRKGL ISSWKAYAPAWAGKVAIEAVDRAMRKEGAPAPIWEGEDGVIAWLLSGPEHTYRVPLPEPGEPKRAILDSY TKEHSAEYQSQALIDLARRMRERIGDLNQIATIVLHTSHHTHYVIGTGAGDPQKFDPDASRETLDHSVMY IFAVALQDGSWHHERSYAPERAHRPDTVELWRKISTVEDPEWTRRYHSTDPNDKAFGARAVVTLKSGEVI VDELAVADAHPLGARPFERTQYVGKFHELAEGVVTDAEQQRFLSVAEGLPALPPGAAGELNIVVDPAVLA TAPAIPGGIF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0346 | - | - | 100% (501) | 2-methylcitrate dehydratase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1161 | - | 0.0 | 79.64% (501) | hypothetical protein Mb1161 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1130 | - | 0.0 | 79.64% (501) | hypothetical protein Rv1130 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4617 | - | 0.0 | 82.24% (501) | methylcitrate dehydratase family protein |
| M. marinum M | MMAR_1379 | - | 0.0 | 82.80% (500) | hypothetical protein MMAR_1379 |
| M. smegmatis MC2 155 | MSMEG_6645 | - | 0.0 | 84.23% (501) | 2-methylcitrate dehydratase 2 |
| M. thermoresistible (build 8) | TH_1875 | - | 0.0 | 82.04% (501) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2496 | - | 0.0 | 83.00% (500) | hypothetical protein MUL_2496 |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1379|M.marinum_M ----------------------------MRMHDVRTRRSAEDFPRREHLA
MUL_2496|M.ulcerans_Agy99 MQNRAGEDTKLRPYRAFTPNVWLRTVRFMRMHDVRTRRSAEDFPRREHLA
MAV_0346|M.avium_104 ----------------------------MRIHDVRTRRSAEDFPRSEHLA
MAB_4617|M.abscessus_ATCC_1997 ----------------------------MPVHSVRTRRSAEAFPRDQHLA
MSMEG_6645|M.smegmatis_MC2_155 -------------------------MRIMRIHDVRTRRSAEDFPRSEHLA
TH_1875|M.thermoresistible__bu ----------------LGFHTVLRTVPIMRIHHVRTRRSADDFPRTEHLA
Mb1161|M.bovis_AF2122/97 ---MPGQDTKVRLFRVFCWCPVLRMVRIMLMHAVRAWRSADDFPCTEHMA
Rv1130|M.tuberculosis_H37Rv ---MPDQDTKVRFFRVFCWCPVLRMVRIMLMHAVRAWRSADDFPCTEHMA
* :* **: ***: ** :*:*
MMAR_1379|M.marinum_M YQIAEVAADPVAVPAETEAMVINRIIDNAAVSAASLTRRPVAVARAQARA
MUL_2496|M.ulcerans_Agy99 YQIAEVAADPVAVPAETEAMVINRIIDNAAVSAASLTRRPVAVARAQARA
MAV_0346|M.avium_104 WKIAEVAADPVAVPAETEAMVINRVIDNAAVSAASVLRRPVTVARAQAQA
MAB_4617|M.abscessus_ATCC_1997 WKIAEIASDPVAVPADTAAMVINRVIDNAAVSAASVIRRPVTVARRQAQA
MSMEG_6645|M.smegmatis_MC2_155 WKIAQVAADPVAVDADVEEMVLNRIIDNAAVSAASVTRRPVAVARAQAQA
TH_1875|M.thermoresistible__bu HKIARVAADPVPVPADTEAMVLNRIIDNAAVSAAAVLRRPVTVARTQALA
Mb1161|M.bovis_AF2122/97 YKIAQVAADPVDVDPEVADMVCNRIIDNAAVSAASMVRRPVTVARHQALA
Rv1130|M.tuberculosis_H37Rv YKIAQVAADPVDVDPEVADMVCNRIIDNAAVSAASMVRRPVTVARHQALA
:**.:*:*** * .:. ** **:*********:: ****:*** ** *
MMAR_1379|M.marinum_M YPRSDRGAKVFGITGNHAPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MUL_2496|M.ulcerans_Agy99 YPRSDRGAKVFGITGNHAPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MAV_0346|M.avium_104 HPAAAKGAKVFGIRGDYSPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MAB_4617|M.abscessus_ATCC_1997 HPAVP-GAHVFGIGGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPGDN
MSMEG_6645|M.smegmatis_MC2_155 H-RANAGATVFGIDGGYSPEWAAWANGVAVRELDFHDTFLAADYSHPGDN
TH_1875|M.thermoresistible__bu HPRRP-GAAVFGVDGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPADN
Mb1161|M.bovis_AF2122/97 HPVRH-GAKVFGVEGSYSADWAAWANGVAARELDFHDTFLAADYSHPADN
Rv1130|M.tuberculosis_H37Rv HPVRH-GAKVFGVEGSYSADWAAWANGVAARELDFHDTFLAADYSHPADN
: ** ***: *.::.:*********.************:****.**
MMAR_1379|M.marinum_M IAPLVAVAQHLGLDGTDLIRGIATGYEIQMALVRGICLHEHKIDHVAHLG
MUL_2496|M.ulcerans_Agy99 IAALVAVAQHLGLDGTDLIRGIATGYEIQMALVRGICLHEHKVDHVAHLG
MAV_0346|M.avium_104 IPALVAVAQHVGVGGADLIRGIATGYEIQIDLARGICLHEHKIDHVAHLG
MAB_4617|M.abscessus_ATCC_1997 IPPLVAVAQQLGIGGDDLIRGLATAYETQINLTRGICLHEHKIDHVAHLG
MSMEG_6645|M.smegmatis_MC2_155 IPPLVAVAQHLGVRGADLIRGLATAYEIQIDLVKGICLHQHKIDHVAHLG
TH_1875|M.thermoresistible__bu IPALVAVAQQLGLGGADLIRGIATAYEIHIALVRGICLHEHKIDHVAHLG
Mb1161|M.bovis_AF2122/97 IPPLVAVAQQLGVCGAELIRGLVTAYEIHIDLTRGICLHEHKIDHVAHLG
Rv1130|M.tuberculosis_H37Rv IPPLVAVAQQLGVCGAELIRGLVTAYEIHIDLTRGICLHEHKIDHVAHLG
*..******::*: * :****:.*.** :: *.:*****:**:*******
MMAR_1379|M.marinum_M PSVAAGLGTMLGLDPDTIYSAVGQALHLTTSTRQSRKGLISSWKAFAPAW
MUL_2496|M.ulcerans_Agy99 PSVAAGLGTMLGLDPDTIYSAVGQALHLTTSTRQSRKGLISSWKAFAPAW
MAV_0346|M.avium_104 PSVAAGLGTMLRLDPETIYQAIGQALHLTTSTRQSRKGLISSWKAYAPAW
MAB_4617|M.abscessus_ATCC_1997 PSVAAGLGTMLKLDTETIYQAIGQALHLTTATRQSRKGLISSWKAYAPAW
MSMEG_6645|M.smegmatis_MC2_155 PSVAAGLGTMLRLDPETIYAAIGQALHLTTATRQSRKGLISSWKAYAPAH
TH_1875|M.thermoresistible__bu PAAAAGLGTLLRLDPDTIYDAIGQALHLTTATRQSRKGLISSWKAFAPAH
Mb1161|M.bovis_AF2122/97 PAVAAGIGTMLRLDQETIYHAIGQALHLTTSTRQSRKGAISSWKAFAPAH
Rv1130|M.tuberculosis_H37Rv PAVAAGIGTMLRLDQETIYHAIGQALHLTTSTRQSRKGAISSWKAFAPAH
*:.***:**:* ** :*** *:********:******* ******:***
MMAR_1379|M.marinum_M AGKVAIEAVDRAMRGEGAPAPIWEGEDGVIAWLLSGPEHTYHVALPGRGE
MUL_2496|M.ulcerans_Agy99 AGKVAIEAVDRAMRGEGAPAPIWEGEDGVIAWLLSGPEHTYHVALPGRGE
MAV_0346|M.avium_104 AGKVAIEAVDRAMRKEGAPAPIWEGEDGVIAWLLSGPEHTYRVPLPEPGE
MAB_4617|M.abscessus_ATCC_1997 AGKVAIEAVDRAMRGEGAPSPIWEGEDGVIAWLLGGPEKLYEVPLPGPGE
MSMEG_6645|M.smegmatis_MC2_155 AGKVAIEAVDRAMRGEGSPAPIWEGEDGVIAWMLAGPEHTYQVPLPEPGE
TH_1875|M.thermoresistible__bu AGKIAVEAVDRAMRGEGSPAPIWEGEDGVIAWLLSGPERTYRVPLPEPGE
Mb1161|M.bovis_AF2122/97 AGKVGIEAVDRAMRGEGSPAPIWEGEDGVIAWLLAGPEHTYRVPLPAPGE
Rv1130|M.tuberculosis_H37Rv AGKVGIEAVDRAMRGEGSPAPIWEGEDGVIAWLLAGPEHTYRVPLPAPGE
***:.:******** **:*:************:*.***: *.*.** **
MMAR_1379|M.marinum_M PKRAILDSYTKEHSAEYQSQALIDLARRMRGRIGDSDQIETIVLHTSHHT
MUL_2496|M.ulcerans_Agy99 PKRAILDSYTKEHSAEYQSQALIDLARRMRGRIGDSDQIETIVLHTSHHT
MAV_0346|M.avium_104 PKRAILDSYTKEHSAEYQSQALIDLARRMRERIGDLNQIATIVLHTSHHT
MAB_4617|M.abscessus_ATCC_1997 EKRAILDSYTKEHSAEYQSQAPIDLARRMRERIGDLAQIATIVLHTSHHT
MSMEG_6645|M.smegmatis_MC2_155 SKRAILDSYTKEHSAEYQSQAPIDLARRMRERIGDLDQIASIVLHTSHHT
TH_1875|M.thermoresistible__bu PKRAILDSYTKEHSAEYQSQAVIDLARRMRQRIGDLGEVESIVLHTSHHT
Mb1161|M.bovis_AF2122/97 PKRAILDSYTKQHSAEYQSQAPIDLACRLRERIGDLDQIASIVLHTSHHT
Rv1130|M.tuberculosis_H37Rv PKRAILDSYTKQHSAEYQSQAPIDLACRLRERIGDLDQIASIVLHTSHHT
**********:********* **** *:* **** :: :*********
MMAR_1379|M.marinum_M HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHVRSYSPQR
MUL_2496|M.ulcerans_Agy99 HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHVRSYSPER
MAV_0346|M.avium_104 HYVIGTGAGDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHERSYAPER
MAB_4617|M.abscessus_ATCC_1997 HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALEDGTWHHERSYAPER
MSMEG_6645|M.smegmatis_MC2_155 HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGVWHHETSYSPER
TH_1875|M.thermoresistible__bu HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGTWHHEHSYAPER
Mb1161|M.bovis_AF2122/97 HVVIGTGSGDPQKFDPDASRETLDHSLPYIFAVALQDGCWHHERSYAPER
Rv1130|M.tuberculosis_H37Rv HVVIGTGSGDPQKFDPDASRETLDHSLPYIFAVALQDGCWHHERSYAPER
* *****:.*****************: *******:** *** **:*:*
MMAR_1379|M.marinum_M AHRPDTVALWHKISTVEDPEWTRRYHSADPAEKAFGARAEITLNTGQVIV
MUL_2496|M.ulcerans_Agy99 AHRPDTVALWHKISTVEDPEWTRRYHSADPAEKAFGARAEITLNTGQVIV
MAV_0346|M.avium_104 AHRPDTVELWRKISTVEDPEWTRRYHSTDPNDKAFGARAVVTLKSGEVIV
MAB_4617|M.abscessus_ATCC_1997 AHRPETIELWNKISTIEDPEWTRRYHSTDPDKKAFGCKAVVTLKNGEVIA
MSMEG_6645|M.smegmatis_MC2_155 AHRPDTIELWRKISTVEDPEWTRRYHATDPAEKAFGARVEITLKSGEVIT
TH_1875|M.thermoresistible__bu ARRPDTVELWRKISTVEDPEWTRRYHSTDPAEKAFGARAVVTLKNGDVIV
Mb1161|M.bovis_AF2122/97 ARRSDTVALWHKISTVEDPEWTRRYHCADPAKKAFGARAEVTLHSGEVIV
Rv1130|M.tuberculosis_H37Rv ARRSDTVALWHKISTVEDPEWTRRYHCADPAKKAFGARAEVTLHSGEVIV
*:*.:*: **.****:**********.:** .****.:. :**:.*:**.
MMAR_1379|M.marinum_M DELAVADAHPLGARPFERKQYVAKFLGLSDGVIGETEQRRFLSTVEGLSS
MUL_2496|M.ulcerans_Agy99 DELAVADAHPLGARPFERKQYVAKFLGLSDGVIGETEQRRFLSTVEGLSS
MAV_0346|M.avium_104 DELAVADAHPLGARPFERTQYVGKFHELAEGVVTDAEQQRFLSVAEGLPA
MAB_4617|M.abscessus_ATCC_1997 DELAIADAHPLGARPFARENYVNKFTALSDGIIAPREQERFLSVAQGLAD
MSMEG_6645|M.smegmatis_MC2_155 DELAVADAHPLGARPFAREQYRNKFVTLADGVVDPAEQQRFLAAVDELAS
TH_1875|M.thermoresistible__bu DELAVADAHPLGARPFGREQYLAKFETLAADVTDAAERQRFLAVVDALPT
Mb1161|M.bovis_AF2122/97 DELAVADAHPLGTRPFERKQYVEKFTELADGVVEPVEQQRFLAVVESLAD
Rv1130|M.tuberculosis_H37Rv DELAVADAHPLGTRPFERKQYVEKFTELADGVVEPVEQQRFLAVVESLAD
****:*******:*** * :* ** *: .: *:.***:..: *.
MMAR_1379|M.marinum_M LPAGSLGGLNPIADAGVLDRSPTIPPGIL-
MUL_2496|M.ulcerans_Agy99 LPAGSLGGLNPIADAGVLDRSPTIPPGIL-
MAV_0346|M.avium_104 LPPGAAGELNIVVDPAVLATAPAIPGGIF-
MAB_4617|M.abscessus_ATCC_1997 LKPGSLGALNPLVDTVVLDKAPSTPEGIFK
MSMEG_6645|M.smegmatis_MC2_155 LKPGGLGVLNVRVDKTVLDKSPTIPSGIFQ
TH_1875|M.thermoresistible__bu AEPGSLDALNLRVDPRVLAAAPPVPAGIF-
Mb1161|M.bovis_AF2122/97 LESGAVGGLNVLVDPRVLDKAPVIPPGIFR
Rv1130|M.tuberculosis_H37Rv LESGAVGGLNVLVDPRVLDKAPVIPPGIFR
.*. . ** .* ** :* * **: