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M. abscessus ATCC 19977 MAB_4617 (-)

annotation: methylcitrate dehydratase family protein
coordinates: 4702159 - 4703664
length: 501

MPVHSVRTRRSAEAFPRDQHLAWKIAEIASDPVAVPADTAAMVINRVIDNAAVSAASVIRRPVTVARRQA
QAHPAVPGAHVFGIGGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPGDNIPPLVAVAQQLGIGGDDLI
RGLATAYETQINLTRGICLHEHKIDHVAHLGPSVAAGLGTMLKLDTETIYQAIGQALHLTTATRQSRKGL
ISSWKAYAPAWAGKVAIEAVDRAMRGEGAPSPIWEGEDGVIAWLLGGPEKLYEVPLPGPGEEKRAILDSY
TKEHSAEYQSQAPIDLARRMRERIGDLAQIATIVLHTSHHTHVVIGTGSNDPQKFDPDASRETLDHSVMY
IFAVALEDGTWHHERSYAPERAHRPETIELWNKISTIEDPEWTRRYHSTDPDKKAFGCKAVVTLKNGEVI
ADELAIADAHPLGARPFARENYVNKFTALSDGIIAPREQERFLSVAQGLADLKPGSLGALNPLVDTVVLD
KAPSTPEGIFK

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. abscessus ATCC 19977 MAB_4617 - - 100% (501) methylcitrate dehydratase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1161 - 0.0 76.45% (501) hypothetical protein Mb1161
M. gilvum PYR-GCK - - - - -
M. tuberculosis H37Rv Rv1130 - 0.0 76.45% (501) hypothetical protein Rv1130
M. leprae Br4923 - - - - -
M. marinum M MMAR_1379 - 0.0 77.80% (500) hypothetical protein MMAR_1379
M. avium 104 MAV_0346 - 0.0 82.24% (501) 2-methylcitrate dehydratase 2
M. smegmatis MC2 155 MSMEG_6645 - 0.0 81.44% (501) 2-methylcitrate dehydratase 2
M. thermoresistible (build 8) TH_1875 - 0.0 78.60% (500) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99 MUL_2496 - 0.0 77.60% (500) hypothetical protein MUL_2496
M. vanbaalenii PYR-1 - - - - -

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1379|M.marinum_M               ----------------------------MRMHDVRTRRSAEDFPRREHLA
MUL_2496|M.ulcerans_Agy99           MQNRAGEDTKLRPYRAFTPNVWLRTVRFMRMHDVRTRRSAEDFPRREHLA
MAV_0346|M.avium_104                ----------------------------MRIHDVRTRRSAEDFPRSEHLA
MAB_4617|M.abscessus_ATCC_1997      ----------------------------MPVHSVRTRRSAEAFPRDQHLA
MSMEG_6645|M.smegmatis_MC2_155      -------------------------MRIMRIHDVRTRRSAEDFPRSEHLA
TH_1875|M.thermoresistible__bu      ----------------LGFHTVLRTVPIMRIHHVRTRRSADDFPRTEHLA
Mb1161|M.bovis_AF2122/97            ---MPGQDTKVRLFRVFCWCPVLRMVRIMLMHAVRAWRSADDFPCTEHMA
Rv1130|M.tuberculosis_H37Rv         ---MPDQDTKVRFFRVFCWCPVLRMVRIMLMHAVRAWRSADDFPCTEHMA
                                                                * :* **: ***: **  :*:*

MMAR_1379|M.marinum_M               YQIAEVAADPVAVPAETEAMVINRIIDNAAVSAASLTRRPVAVARAQARA
MUL_2496|M.ulcerans_Agy99           YQIAEVAADPVAVPAETEAMVINRIIDNAAVSAASLTRRPVAVARAQARA
MAV_0346|M.avium_104                WKIAEVAADPVAVPAETEAMVINRVIDNAAVSAASVLRRPVTVARAQAQA
MAB_4617|M.abscessus_ATCC_1997      WKIAEIASDPVAVPADTAAMVINRVIDNAAVSAASVIRRPVTVARRQAQA
MSMEG_6645|M.smegmatis_MC2_155      WKIAQVAADPVAVDADVEEMVLNRIIDNAAVSAASVTRRPVAVARAQAQA
TH_1875|M.thermoresistible__bu      HKIARVAADPVPVPADTEAMVLNRIIDNAAVSAAAVLRRPVTVARTQALA
Mb1161|M.bovis_AF2122/97            YKIAQVAADPVDVDPEVADMVCNRIIDNAAVSAASMVRRPVTVARHQALA
Rv1130|M.tuberculosis_H37Rv         YKIAQVAADPVDVDPEVADMVCNRIIDNAAVSAASMVRRPVTVARHQALA
                                     :**.:*:*** * .:.  ** **:*********:: ****:*** ** *

MMAR_1379|M.marinum_M               YPRSDRGAKVFGITGNHAPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MUL_2496|M.ulcerans_Agy99           YPRSDRGAKVFGITGNHAPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MAV_0346|M.avium_104                HPAAAKGAKVFGIRGDYSPEWAAWANGVAVRELDFHDTFLAAEYSHPGDN
MAB_4617|M.abscessus_ATCC_1997      HPAVP-GAHVFGIGGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPGDN
MSMEG_6645|M.smegmatis_MC2_155      H-RANAGATVFGIDGGYSPEWAAWANGVAVRELDFHDTFLAADYSHPGDN
TH_1875|M.thermoresistible__bu      HPRRP-GAAVFGVDGGYSAEWAAWANGVAVRELDFHDTFLAADYSHPADN
Mb1161|M.bovis_AF2122/97            HPVRH-GAKVFGVEGSYSADWAAWANGVAARELDFHDTFLAADYSHPADN
Rv1130|M.tuberculosis_H37Rv         HPVRH-GAKVFGVEGSYSADWAAWANGVAARELDFHDTFLAADYSHPADN
                                    :     ** ***: *.::.:*********.************:****.**

MMAR_1379|M.marinum_M               IAPLVAVAQHLGLDGTDLIRGIATGYEIQMALVRGICLHEHKIDHVAHLG
MUL_2496|M.ulcerans_Agy99           IAALVAVAQHLGLDGTDLIRGIATGYEIQMALVRGICLHEHKVDHVAHLG
MAV_0346|M.avium_104                IPALVAVAQHVGVGGADLIRGIATGYEIQIDLARGICLHEHKIDHVAHLG
MAB_4617|M.abscessus_ATCC_1997      IPPLVAVAQQLGIGGDDLIRGLATAYETQINLTRGICLHEHKIDHVAHLG
MSMEG_6645|M.smegmatis_MC2_155      IPPLVAVAQHLGVRGADLIRGLATAYEIQIDLVKGICLHQHKIDHVAHLG
TH_1875|M.thermoresistible__bu      IPALVAVAQQLGLGGADLIRGIATAYEIHIALVRGICLHEHKIDHVAHLG
Mb1161|M.bovis_AF2122/97            IPPLVAVAQQLGVCGAELIRGLVTAYEIHIDLTRGICLHEHKIDHVAHLG
Rv1130|M.tuberculosis_H37Rv         IPPLVAVAQQLGVCGAELIRGLVTAYEIHIDLTRGICLHEHKIDHVAHLG
                                    *..******::*: * :****:.*.** :: *.:*****:**:*******

MMAR_1379|M.marinum_M               PSVAAGLGTMLGLDPDTIYSAVGQALHLTTSTRQSRKGLISSWKAFAPAW
MUL_2496|M.ulcerans_Agy99           PSVAAGLGTMLGLDPDTIYSAVGQALHLTTSTRQSRKGLISSWKAFAPAW
MAV_0346|M.avium_104                PSVAAGLGTMLRLDPETIYQAIGQALHLTTSTRQSRKGLISSWKAYAPAW
MAB_4617|M.abscessus_ATCC_1997      PSVAAGLGTMLKLDTETIYQAIGQALHLTTATRQSRKGLISSWKAYAPAW
MSMEG_6645|M.smegmatis_MC2_155      PSVAAGLGTMLRLDPETIYAAIGQALHLTTATRQSRKGLISSWKAYAPAH
TH_1875|M.thermoresistible__bu      PAAAAGLGTLLRLDPDTIYDAIGQALHLTTATRQSRKGLISSWKAFAPAH
Mb1161|M.bovis_AF2122/97            PAVAAGIGTMLRLDQETIYHAIGQALHLTTSTRQSRKGAISSWKAFAPAH
Rv1130|M.tuberculosis_H37Rv         PAVAAGIGTMLRLDQETIYHAIGQALHLTTSTRQSRKGAISSWKAFAPAH
                                    *:.***:**:* ** :*** *:********:******* ******:*** 

MMAR_1379|M.marinum_M               AGKVAIEAVDRAMRGEGAPAPIWEGEDGVIAWLLSGPEHTYHVALPGRGE
MUL_2496|M.ulcerans_Agy99           AGKVAIEAVDRAMRGEGAPAPIWEGEDGVIAWLLSGPEHTYHVALPGRGE
MAV_0346|M.avium_104                AGKVAIEAVDRAMRKEGAPAPIWEGEDGVIAWLLSGPEHTYRVPLPEPGE
MAB_4617|M.abscessus_ATCC_1997      AGKVAIEAVDRAMRGEGAPSPIWEGEDGVIAWLLGGPEKLYEVPLPGPGE
MSMEG_6645|M.smegmatis_MC2_155      AGKVAIEAVDRAMRGEGSPAPIWEGEDGVIAWMLAGPEHTYQVPLPEPGE
TH_1875|M.thermoresistible__bu      AGKIAVEAVDRAMRGEGSPAPIWEGEDGVIAWLLSGPERTYRVPLPEPGE
Mb1161|M.bovis_AF2122/97            AGKVGIEAVDRAMRGEGSPAPIWEGEDGVIAWLLAGPEHTYRVPLPAPGE
Rv1130|M.tuberculosis_H37Rv         AGKVGIEAVDRAMRGEGSPAPIWEGEDGVIAWLLAGPEHTYRVPLPAPGE
                                    ***:.:******** **:*:************:*.***: *.*.**  **

MMAR_1379|M.marinum_M               PKRAILDSYTKEHSAEYQSQALIDLARRMRGRIGDSDQIETIVLHTSHHT
MUL_2496|M.ulcerans_Agy99           PKRAILDSYTKEHSAEYQSQALIDLARRMRGRIGDSDQIETIVLHTSHHT
MAV_0346|M.avium_104                PKRAILDSYTKEHSAEYQSQALIDLARRMRERIGDLNQIATIVLHTSHHT
MAB_4617|M.abscessus_ATCC_1997      EKRAILDSYTKEHSAEYQSQAPIDLARRMRERIGDLAQIATIVLHTSHHT
MSMEG_6645|M.smegmatis_MC2_155      SKRAILDSYTKEHSAEYQSQAPIDLARRMRERIGDLDQIASIVLHTSHHT
TH_1875|M.thermoresistible__bu      PKRAILDSYTKEHSAEYQSQAVIDLARRMRQRIGDLGEVESIVLHTSHHT
Mb1161|M.bovis_AF2122/97            PKRAILDSYTKQHSAEYQSQAPIDLACRLRERIGDLDQIASIVLHTSHHT
Rv1130|M.tuberculosis_H37Rv         PKRAILDSYTKQHSAEYQSQAPIDLACRLRERIGDLDQIASIVLHTSHHT
                                     **********:********* **** *:* ****  :: :*********

MMAR_1379|M.marinum_M               HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHVRSYSPQR
MUL_2496|M.ulcerans_Agy99           HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHVRSYSPER
MAV_0346|M.avium_104                HYVIGTGAGDPQKFDPDASRETLDHSVMYIFAVALQDGSWHHERSYAPER
MAB_4617|M.abscessus_ATCC_1997      HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALEDGTWHHERSYAPER
MSMEG_6645|M.smegmatis_MC2_155      HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGVWHHETSYSPER
TH_1875|M.thermoresistible__bu      HVVIGTGSNDPQKFDPDASRETLDHSVMYIFAVALQDGTWHHEHSYAPER
Mb1161|M.bovis_AF2122/97            HVVIGTGSGDPQKFDPDASRETLDHSLPYIFAVALQDGCWHHERSYAPER
Rv1130|M.tuberculosis_H37Rv         HVVIGTGSGDPQKFDPDASRETLDHSLPYIFAVALQDGCWHHERSYAPER
                                    * *****:.*****************: *******:** ***  **:*:*

MMAR_1379|M.marinum_M               AHRPDTVALWHKISTVEDPEWTRRYHSADPAEKAFGARAEITLNTGQVIV
MUL_2496|M.ulcerans_Agy99           AHRPDTVALWHKISTVEDPEWTRRYHSADPAEKAFGARAEITLNTGQVIV
MAV_0346|M.avium_104                AHRPDTVELWRKISTVEDPEWTRRYHSTDPNDKAFGARAVVTLKSGEVIV
MAB_4617|M.abscessus_ATCC_1997      AHRPETIELWNKISTIEDPEWTRRYHSTDPDKKAFGCKAVVTLKNGEVIA
MSMEG_6645|M.smegmatis_MC2_155      AHRPDTIELWRKISTVEDPEWTRRYHATDPAEKAFGARVEITLKSGEVIT
TH_1875|M.thermoresistible__bu      ARRPDTVELWRKISTVEDPEWTRRYHSTDPAEKAFGARAVVTLKNGDVIV
Mb1161|M.bovis_AF2122/97            ARRSDTVALWHKISTVEDPEWTRRYHCADPAKKAFGARAEVTLHSGEVIV
Rv1130|M.tuberculosis_H37Rv         ARRSDTVALWHKISTVEDPEWTRRYHCADPAKKAFGARAEVTLHSGEVIV
                                    *:*.:*: **.****:**********.:** .****.:. :**:.*:**.

MMAR_1379|M.marinum_M               DELAVADAHPLGARPFERKQYVAKFLGLSDGVIGETEQRRFLSTVEGLSS
MUL_2496|M.ulcerans_Agy99           DELAVADAHPLGARPFERKQYVAKFLGLSDGVIGETEQRRFLSTVEGLSS
MAV_0346|M.avium_104                DELAVADAHPLGARPFERTQYVGKFHELAEGVVTDAEQQRFLSVAEGLPA
MAB_4617|M.abscessus_ATCC_1997      DELAIADAHPLGARPFARENYVNKFTALSDGIIAPREQERFLSVAQGLAD
MSMEG_6645|M.smegmatis_MC2_155      DELAVADAHPLGARPFAREQYRNKFVTLADGVVDPAEQQRFLAAVDELAS
TH_1875|M.thermoresistible__bu      DELAVADAHPLGARPFGREQYLAKFETLAADVTDAAERQRFLAVVDALPT
Mb1161|M.bovis_AF2122/97            DELAVADAHPLGTRPFERKQYVEKFTELADGVVEPVEQQRFLAVVESLAD
Rv1130|M.tuberculosis_H37Rv         DELAVADAHPLGTRPFERKQYVEKFTELADGVVEPVEQQRFLAVVESLAD
                                    ****:*******:*** * :*  **  *: .:    *:.***:..: *. 

MMAR_1379|M.marinum_M               LPAGSLGGLNPIADAGVLDRSPTIPPGIL-
MUL_2496|M.ulcerans_Agy99           LPAGSLGGLNPIADAGVLDRSPTIPPGIL-
MAV_0346|M.avium_104                LPPGAAGELNIVVDPAVLATAPAIPGGIF-
MAB_4617|M.abscessus_ATCC_1997      LKPGSLGALNPLVDTVVLDKAPSTPEGIFK
MSMEG_6645|M.smegmatis_MC2_155      LKPGGLGVLNVRVDKTVLDKSPTIPSGIFQ
TH_1875|M.thermoresistible__bu      AEPGSLDALNLRVDPRVLAAAPPVPAGIF-
Mb1161|M.bovis_AF2122/97            LESGAVGGLNVLVDPRVLDKAPVIPPGIFR
Rv1130|M.tuberculosis_H37Rv         LESGAVGGLNVLVDPRVLDKAPVIPPGIFR
                                      .*. . **  .*  **  :*  * **:

species	id	gene	e-value	identity (len)	annotation
M. abscessus ATCC 19977	MAB_4617	-	-	100% (501)	methylcitrate dehydratase family protein