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CWTNRTRSSHRRRAPTCGPNRAAPPGPHRDVRDHARFHQFTVTRKSGFEMAGILALATAAGSGIEPAEQT GLIGQIIAQLAHRGQRGFSLIAQQVSGTESGYFSELPAANLDQGAIAEGLGGQRMRALLGHVHQTRADMN NQPFSSDQPVTGAQPRRPFALHVAMDGGIVNTSELAQELSAAGVKISAGSDVEILTRVVEQICVSKYVNR GLRPDYAEVFREIDLKVDGAVSAVLVDDAGVVVAYRNWQGLRPLSVWQRPEVIAVASEIDSAAAETGSIL ELQASQIAVIESAGGGQIQVQFVGRAAHRPKKCVFETLYLGHPRTRFHGETHWETRRKIGFELGALLGQT LAGTEDLIVASMPKTGIPYADGLFEYLQTHAPKNAVVREELVKIGLAQRTLIGIPGERKALIERKYSLRD VDVTGRNVIVVDEALIRGDTSRAVAQLLFDAGARSVHWVVGSPPFISPSYYGLGVNSLEELIFWQIWSSL ALKPERPWLELNSRDPQLLSFFESLVATDIGVTRVTYLPFHRLTRVLPGGEYDYDCSPFTFRMPTPIGQV RADEEYLQILEQRCAPEEMVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4880c | - | - | 100% (582) | amidophosphoribosyltransferase PurF |
| M. abscessus ATCC 19977 | MAB_0713 | - | 3e-23 | 26.21% (435) | amidophosphoribosyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0831 | purF | 4e-21 | 25.62% (441) | amidophosphoribosyltransferase |
| M. gilvum PYR-GCK | Mflv_1634 | - | 3e-22 | 26.15% (436) | amidophosphoribosyltransferase |
| M. tuberculosis H37Rv | Rv0808 | purF | 4e-21 | 25.62% (441) | amidophosphoribosyltransferase |
| M. leprae Br4923 | MLBr_02206 | purF | 1e-22 | 26.41% (443) | amidophosphoribosyltransferase |
| M. marinum M | MMAR_4881 | purF | 2e-21 | 25.74% (439) | amidophosphoribosyltransferase, PurF |
| M. avium 104 | MAV_0747 | purF | 2e-23 | 26.98% (441) | amidophosphoribosyltransferase |
| M. smegmatis MC2 155 | MSMEG_5800 | purF | 1e-22 | 26.15% (436) | amidophosphoribosyltransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0417 | purF | 4e-21 | 25.74% (439) | amidophosphoribosyltransferase |
| M. vanbaalenii PYR-1 | Mvan_5114 | - | 5e-23 | 26.61% (436) | amidophosphoribosyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02206|M.leprae_Br4923 MCLAVGVGVRAPKHVPQIRRLGRAGRRLRCVTNCALGSCPIVTVQQPGRD
MAV_0747|M.avium_104 -----------------------------------------MTVAEPEQD
Mb0831|M.bovis_AF2122/97 -----------------------MAVDSDYVTDRAAGSRQTVTGQQPEQD
Rv0808|M.tuberculosis_H37Rv -----------------------MAVDSDYVTDRAAGSRQTVTGQQPEQD
MMAR_4881|M.marinum_M -----------------------------------------MTAQQSEED
MUL_0417|M.ulcerans_Agy99 ---MFNEEDGQKENAGLIRPHGHGGRRLLLVTNRAPGSRQTVTTQQSEED
Mflv_1634|M.gilvum_PYR-GCK -----------------------------------------MTAEQLE--
Mvan_5114|M.vanbaalenii_PYR-1 -----------------------------------------MTAEQLE--
MSMEG_5800|M.smegmatis_MC2_155 --------------------------------------MIGHDDNESE--
MAB_4880c|M.abscessus_ATCC_199 ------MCWTNRTRSSHRRRAPTCGPNRAAPPGPHRDVRDHARFHQFTVT
:
MLBr_02206|M.leprae_Br4923 FSSPREECGVFGVWAPG--------------ELVAKLTYFGLYALQHRGQ
MAV_0747|M.avium_104 FNAPREECGVFGVWAPG--------------EEVAKLTYYGLYALQHRGQ
Mb0831|M.bovis_AF2122/97 LNSPREECGVFGVWAPG--------------EDVAKLTYYGLYALQHRGQ
Rv0808|M.tuberculosis_H37Rv LNSPREECGVFGVWAPG--------------EDVAKLTYYGLYALQHRGQ
MMAR_4881|M.marinum_M FNAPREECGVFGVWAPG--------------EDVAKLSYYGLYALQHRGQ
MUL_0417|M.ulcerans_Agy99 FNAPREECGVFGVWAPG--------------EDVAKLSYYGLYALQHRGQ
Mflv_1634|M.gilvum_PYR-GCK -NEPREECGVFGVWAPG--------------EEVSKLTYYGLYALQHRGQ
Mvan_5114|M.vanbaalenii_PYR-1 -SEPREECGVFGVWAPG--------------EEVAKLTYYGLYALQHRGQ
MSMEG_5800|M.smegmatis_MC2_155 -NEPREECGVFGVWAPG--------------EEVAKLTYYGLYALQHRGQ
MAB_4880c|M.abscessus_ATCC_199 RKSGFEMAGILALATAAGSGIEPAEQTGLIGQIIAQLAHRGQRGFSLIAQ
. * .*::.: :.. : :::*:: * .:. .*
MLBr_02206|M.leprae_Br4923 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMEGHVAIGHCRYSTTG
MAV_0747|M.avium_104 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTG
Mb0831|M.bovis_AF2122/97 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTG
Rv0808|M.tuberculosis_H37Rv EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTG
MMAR_4881|M.marinum_M EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTG
MUL_0417|M.ulcerans_Agy99 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTG
Mflv_1634|M.gilvum_PYR-GCK EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMPGHVAVGHCRYSTTG
Mvan_5114|M.vanbaalenii_PYR-1 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMHGHVAIGHCRYSTTG
MSMEG_5800|M.smegmatis_MC2_155 EAAGIAVADGSQVLVF-KDLGLVSQVFDEQTLAAMPGHVAVGHCRYSTTG
MAB_4880c|M.abscessus_ATCC_199 QVSGTESGYFSELPAANLDQGAIAEGLGGQRMRALLGHVHQTRADMNNQ-
:.:* . *:: . * * ::: :. * : *: *** :. ..
MLBr_02206|M.leprae_Br4923 DTTWENAQPVFRNIAAG-SGVALGHNGNLVNTAELAARARDAGLIAKRCP
MAV_0747|M.avium_104 DTTWENAQPVFRNTAAG-TGVALGHNGNLVNTAELAARARDAGLIAKRAP
Mb0831|M.bovis_AF2122/97 DTTWENAQPVFRNTAAG-TGVALGHNGNLVNAAALAARARDAGLIATRCP
Rv0808|M.tuberculosis_H37Rv DTTWENAQPVFRNTAAG-TGVALGHNGNLVNAAALAARARDAGLIATRCP
MMAR_4881|M.marinum_M DTTWENAQPVFRNTAAG-TGVALGHNGNLVNAAALAARARDEGLIGNRSS
MUL_0417|M.ulcerans_Agy99 DTTWENAQPVFRNTAAG-TGVALGHNGNLVNAAALAARARDEGLIGNRSS
Mflv_1634|M.gilvum_PYR-GCK STTWENAQPVFRNTAAG-TGVALGHNGNLVNTAELAARARDEGLMNDRGA
Mvan_5114|M.vanbaalenii_PYR-1 STTWENAQPVFRNTAAG-TGVALGHNGNLVNTAELAARARDEGLMSSRGA
MSMEG_5800|M.smegmatis_MC2_155 STTWENAQPVFRNTAAG-TGVALGHNGNLVNTAELAARARDNGLIELKGG
MAB_4880c|M.abscessus_ATCC_199 --PFSSDQPVTGAQPRRPFALHVAMDGGIVNTSELAQELSAAGVKISAGS
.:.. *** . .: :. :*.:**:: ** . *:
MLBr_02206|M.leprae_Br4923 APATTD---SDILGALLAHGAADSTLEQAALELLPTVRGAFCLTFMDEN-
MAV_0747|M.avium_104 APATTD---SDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDEN-
Mb0831|M.bovis_AF2122/97 APATTD---SDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDEN-
Rv0808|M.tuberculosis_H37Rv APATTD---SDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDEN-
MMAR_4881|M.marinum_M APATTD---SDILGALLAHGAADSSLEQAALELLPTVRGAFCLTFMDEN-
MUL_0417|M.ulcerans_Agy99 APATTD---SDILGALLAHGAADSSLEQAALELLPTVRGAFCLTFMDEN-
Mflv_1634|M.gilvum_PYR-GCK ATATTD---SDILGALLAHGAADSSLEQAALELLPTVRGAFCLTFMDEN-
Mvan_5114|M.vanbaalenii_PYR-1 ATATTD---SDILGALLAHGAADSSLEQAALELLPTVRGAFCLTFMDEN-
MSMEG_5800|M.smegmatis_MC2_155 PAATTD---SDILGALLAHGAADATLEQAALELLPTVRGAFCLTFMDEN-
MAB_4880c|M.abscessus_ATCC_199 DVEILTRVVEQICVSKYVNRGLRPDYAEVFREIDLKVDGAVSAVLVDDAG
.:* : .: . . :. :: .* **.. .::*:
MLBr_02206|M.leprae_Br4923 TLYACRDPYGVRPLSLGRLDRGWVVASETAGLDIVGASFVRDIEPGELLA
MAV_0747|M.avium_104 TLYACRDPHGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
Mb0831|M.bovis_AF2122/97 TLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
Rv0808|M.tuberculosis_H37Rv TLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
MMAR_4881|M.marinum_M TLYACRDPHGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
MUL_0417|M.ulcerans_Agy99 TLYACRDPHGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
Mflv_1634|M.gilvum_PYR-GCK TLYAARDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
Mvan_5114|M.vanbaalenii_PYR-1 TLYAARDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
MSMEG_5800|M.smegmatis_MC2_155 TLYAARDPHGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLA
MAB_4880c|M.abscessus_ATCC_199 VVVAYRNWQGLRPLSVWQRPEVIAVASEIDSAAAETGSIL-ELQASQIAV
.: * *: *:****: : . .**** . .*:: :::..:: .
MLBr_02206|M.leprae_Br4923 IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSTLAGRSVHGTR---
MAV_0747|M.avium_104 IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHATR---
Mb0831|M.bovis_AF2122/97 IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAAR---
Rv0808|M.tuberculosis_H37Rv IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAAR---
MMAR_4881|M.marinum_M IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSMLNGRSVHAAR---
MUL_0417|M.ulcerans_Agy99 IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSMLNGRSVHAAR---
Mflv_1634|M.gilvum_PYR-GCK IDADG-----VRSTRFANPTPKGCVFEYVYLARPDSTIVGRSVHATR---
Mvan_5114|M.vanbaalenii_PYR-1 IDADG-----VRSSRFAPPSPKGCVFEYVYLARPDSTIVGRSVHATR---
MSMEG_5800|M.smegmatis_MC2_155 IDADG-----VRSTRFANPEPKGCVFEYVYLARPDSTLVGRSVHATR---
MAB_4880c|M.abscessus_ATCC_199 IESAGGGQIQVQFVGRAAHRPKKCVFETLYLGHPRTRFHGETHWETRRKI
*:: * *: * ** **** :**.:* : : *.: :*
MLBr_02206|M.leprae_Br4923 -VEIGRRLARECPVEADLVIG-VPESGTPAAVGYAQ------ESGISYGQ
MAV_0747|M.avium_104 -VEIGRRLARERPVEADLVIG-VPESGTPAAVGYAQ------ESGIPYGQ
Mb0831|M.bovis_AF2122/97 -VEIGRRLARECPVEADLVIG-VPESGTPAAVGYAQ------ESGVPYGQ
Rv0808|M.tuberculosis_H37Rv -VEIGRRLARECPVEADLVIG-VPESGTPAAVGYAQ------ESGVPYGQ
MMAR_4881|M.marinum_M -VAIGRRLAQERRVEADLVIG-VPESGTPAAVGYAQ------ESGIPYGQ
MUL_0417|M.ulcerans_Agy99 -VAIGRRLAQERGVEADLVIG-VPESGTPAAVGYAQ------ESGIPYGQ
Mflv_1634|M.gilvum_PYR-GCK -VDIGRRLAREKPIDADLVIG-VPESGTPAAVGYAQ------ESGIPFGQ
Mvan_5114|M.vanbaalenii_PYR-1 -VDIGRRLAREKPVDADLVIG-VPESGTPAAVGYAQ------ESGIPFGQ
MSMEG_5800|M.smegmatis_MC2_155 -VDIGRRLAREHPVEADLVIG-VPESGTPAAVGYAQ------ESGIPFGQ
MAB_4880c|M.abscessus_ATCC_199 GFELGALLGQTLAGTEDLIVASMPKTGIPYADGLFEYLQTHAPKNAVVRE
. :* *.: **::. :*::* * * * : .. :
MLBr_02206|M.leprae_Br4923 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSVVRG
MAV_0747|M.avium_104 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLREVIRGKRLIVVDDSIVRG
Mb0831|M.bovis_AF2122/97 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRG
Rv0808|M.tuberculosis_H37Rv GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRG
MMAR_4881|M.marinum_M GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRG
MUL_0417|M.ulcerans_Agy99 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKDVIRAKRLIVVDDSIVRG
Mflv_1634|M.gilvum_PYR-GCK GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRG
Mvan_5114|M.vanbaalenii_PYR-1 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRG
MSMEG_5800|M.smegmatis_MC2_155 GLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLREVIRGKRLIVVDDSIVRG
MAB_4880c|M.abscessus_ATCC_199 ELVKIGLAQRTLIG-IPGERKALIERKYSLRDVDVTGRNVIVVDEALIRG
*:* . . **:* *: *. * . : .:.:****::::**
MLBr_02206|M.leprae_Br4923 NTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANVVA-
MAV_0747|M.avium_104 NTQRALLRMLREAGAVEVHVRIASPPVKWPCFYGIDFPSPAELIANAVE-
Mb0831|M.bovis_AF2122/97 NTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVE-
Rv0808|M.tuberculosis_H37Rv NTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVE-
MMAR_4881|M.marinum_M NTQRALVRMLREAGAVEVHVRIASPPVKWPCFYGIDFPSPAELIANAVE-
MUL_0417|M.ulcerans_Agy99 NTQRALVRMLREAGAVEVHVRIASPPVKWPCFYGIDFPSPAELIANAVE-
Mflv_1634|M.gilvum_PYR-GCK NTQRALIRMLREAGAVEVHVRIASPPVKWPCFYGIDFATPAELIANAASN
Mvan_5114|M.vanbaalenii_PYR-1 NTQRALIRMLREAGALEVHVRIASPPVKWPCFYGIDFATPAELIANASNA
MSMEG_5800|M.smegmatis_MC2_155 NTQRALVRMLREAGALEVHVRIASPPVRWPCFYGIDFATPAELIANAASQ
MAB_4880c|M.abscessus_ATCC_199 DTSRAVAQLLFDAGARSVHWVVGSPPFISPSYYGLGVNSLEELIFWQIWS
:*.**: ::* :*** .:* :.***. *.:**:.. : ***
MLBr_02206|M.leprae_Br4923 --DEEEMLEAVRQGIGADTLGYISLRGMIAASEQ--------PASRLCYA
MAV_0747|M.avium_104 --DKHEMLEAVRHAIGADSLGYISLRGLIAASEQ--------PASRLCTA
Mb0831|M.bovis_AF2122/97 --NEDEMLEAVRHAIGADTLGYISLRGMVAASEQ--------PTSRLCTA
Rv0808|M.tuberculosis_H37Rv --NEDEMLEAVRHAIGADTLGYISLRGMVAASEQ--------PTSRLCTA
MMAR_4881|M.marinum_M --DENEMLEAVRHVINADTLGYISLRGLVAATEQ--------PISRLCTA
MUL_0417|M.ulcerans_Agy99 --DENEMLEAVRHVINADTLGYISLRGLVAATEQ--------PISRLCTA
Mflv_1634|M.gilvum_PYR-GCK SADDDGMLDGVRRAIGADTLAYISREGMIAATEQ--------PATRLCSA
Mvan_5114|M.vanbaalenii_PYR-1 EADEDEMLDAVRHAIGADSLGYISQQGMIAATEQ--------PASRLCSA
MSMEG_5800|M.smegmatis_MC2_155 EHEG-EMLEAVRHAIGADSLGYISQQGMIAATEQ--------PASRLCSA
MAB_4880c|M.abscessus_ATCC_199 --SLALKPERPWLELNSRDPQLLSFFESLVATDIGVTRVTYLPFHRLTRV
. : :.: :* :.*:: * ** .
MLBr_02206|M.leprae_Br4923 CFDGRYPIELPSEAMLGKNVIEHMLANAARGAGLRDLAA-DQVPVDADEN
MAV_0747|M.avium_104 CFDGQYPIELPGETALGKNVIEHMLANAARGAGLDDLAA-DEVPVVH---
Mb0831|M.bovis_AF2122/97 CFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR---
Rv0808|M.tuberculosis_H37Rv CFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR---
MMAR_4881|M.marinum_M CFDGKYPIELPGETALGKNVIEHMLANAARGAELGDVAT-DEVPIGH---
MUL_0417|M.ulcerans_Agy99 CFDGKYPIELPGETALGKNVIEHMLANAARGAELGDVAT-DEVPIGH---
Mflv_1634|M.gilvum_PYR-GCK CFDGDYPIELPGETALGKNVIEHMLATAARTGLPVSPADNDNASALRRP-
Mvan_5114|M.vanbaalenii_PYR-1 CFDGDYPIELPGETALGKNVIEHMLATAARTGIPLQ-VDNDNVSALRRP-
MSMEG_5800|M.smegmatis_MC2_155 CFDGKYPIELPGETALGKNVIEHMLASAARSGIPVA--QNDNASALRRP-
MAB_4880c|M.abscessus_ATCC_199 LPGGEYDYDCSPFTFRMPTPIGQVRADEEYLQILEQRCAPEEMVG-----
.* * : . : . * :: * ::
MLBr_02206|M.leprae_Br4923 CVWR
MAV_0747|M.avium_104 ----
Mb0831|M.bovis_AF2122/97 ----
Rv0808|M.tuberculosis_H37Rv ----
MMAR_4881|M.marinum_M ----
MUL_0417|M.ulcerans_Agy99 ----
Mflv_1634|M.gilvum_PYR-GCK ----
Mvan_5114|M.vanbaalenii_PYR-1 ----
MSMEG_5800|M.smegmatis_MC2_155 ----
MAB_4880c|M.abscessus_ATCC_199 ----