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TISTYRPKGVQPIIDAGQRIAQSIRRLGHMLAFFVEAIASIPNALRYYSKEFFRLLADVTWGNGSLVTGG GTVGVAAVLGATIGALIGIEAYNLLNIIGLGPATGFISSLVSTRELAPVMAALAFAMQAGCRFTAQLGAQ RINEEIDALDALAIRPIPYLVTTRLLASTVAVVPLYLLCLVISYITCRLLVGISSGGSIGGAYNHYFTMM LSGTDVVYSVIKAVVFVWIASTIQCYFGFNASGGPEGVGVAAGHAMRAAITVVIIVNMLLTMALWGVDAG ARFGG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4600c | - | - | 100% (286) | putative YrbE family protein |
| M. abscessus ATCC 19977 | MAB_4517c | - | e-116 | 69.58% (286) | putative YrbE family protein |
| M. abscessus ATCC 19977 | MAB_1011c | - | e-114 | 68.18% (286) | putative YrbE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3530c | yrbE4B | 2e-55 | 38.58% (267) | integral membrane protein YrbE4b |
| M. gilvum PYR-GCK | Mflv_0011 | - | 1e-114 | 69.23% (286) | hypothetical protein Mflv_0011 |
| M. tuberculosis H37Rv | Rv3500c | yrbE4B | 2e-55 | 38.58% (267) | integral membrane protein YrbE4b |
| M. leprae Br4923 | MLBr_02588 | yrbE1B | 6e-52 | 37.13% (272) | hypothetical protein MLBr_02588 |
| M. marinum M | MMAR_3863 | - | 1e-113 | 67.71% (288) | integral ABC-type transport protein |
| M. avium 104 | MAV_0101 | - | 1e-115 | 68.53% (286) | ABC-transporter integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_1142 | - | 1e-115 | 69.58% (286) | ABC-transporter integral membrane protein |
| M. thermoresistible (build 8) | TH_3777 | - | 1e-113 | 68.90% (283) | PUTATIVE protein of unknown function DUF140 |
| M. ulcerans Agy99 | MUL_4920 | yrbE6B | 1e-107 | 68.15% (270) | integral membrane protein YrbE6B |
| M. vanbaalenii PYR-1 | Mvan_0958 | - | 1e-116 | 70.63% (286) | hypothetical protein Mvan_0958 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0011|M.gilvum_PYR-GCK MSASTFSP---AVVRPAKK-AYRMLATPIIRLGHMLVFFVRALLGIPVAI
Mvan_0958|M.vanbaalenii_PYR-1 MTASSFTP---TLVAPVVR-AYRKISTPLVRLGHMLVFFVRALHGLPVAL
MSMEG_1142|M.smegmatis_MC2_155 MTASPYVP---TLLAPWVR-FGQRASKPIVRLGHMLVFFVRAVAAIPIVL
TH_3777|M.thermoresistible__bu -MAATYVP---PVLTPFVR-LYRKATPPIARLGHMLVFFVRAIVGIPVAL
MMAR_3863|M.marinum_M MTVSAYRPLA-PITEQVVR-LYRRTTKPIIRLGHMLVFFFRALAGVPIAV
MAV_0101|M.avium_104 MTASTYIP---GLARPFVG-AYRVAAAPTMRLGHMLVFFVRAVLAVPTVL
MAB_4600c|M.abscessus_ATCC_199 MTISTYRP---KGVQPIID-AGQRIAQSIRRLGHMLAFFVEAIASIPNAL
MUL_4920|M.ulcerans_Agy99 MTSFVAMRRM-SIRQIVFAGAGAGAGQPLARFGHMIAFYLHTVLAIPVAL
Mb3530c|M.bovis_AF2122/97 MSYDVTIRFR---------RFFSRLQRPVDNFGEQALFYGETMRYVPNAI
Rv3500c|M.tuberculosis_H37Rv MSYDVTIRFR---------RFFSRLQRPVDNFGEQALFYGETMRYVPNAI
MLBr_02588|M.leprae_Br4923 MSTAAVLRARFPRAAANLNRYGGAAARGIDDIGQMSWFGLIALGNIPNAL
:*. * :: :* .:
Mflv_0011|M.gilvum_PYR-GCK SHYRKEFVRLLSDIAWGNGSLVVGGGTAGVAIVLGITVGALVGIEGYNFL
Mvan_0958|M.vanbaalenii_PYR-1 RHYRKEFVRLLSDIAWGNGSLVVGGGTAGVAVVLGITVGALVGIEGYNFL
MSMEG_1142|M.smegmatis_MC2_155 RHYRGEFVRLLSDIAWGNGSLVVGGGTAGVAVVLGITVGALVGIEGYNFL
TH_3777|M.thermoresistible__bu RHYRSEFVRLLSDIAWGNGSLVVGGGTAGVAIVLGVTVGALVGIEGYNFL
MMAR_3863|M.marinum_M RQYRGEFLRLLSNITWGNGSIVVGGGTAGVAVVLGMTVGALLGIEGYNFL
MAV_0101|M.avium_104 RQYRTEFLRLLSNIAWGNGSIVVGGGTAGVAVVLGFTAGALVAVEGYNFL
MAB_4600c|M.abscessus_ATCC_199 RYYSKEFFRLLADVTWGNGSLVTGGGTVGVAAVLGATIGALIGIEAYNLL
MUL_4920|M.ulcerans_Agy99 RRYRREFMRLLSDITWGNGSIVVGGGTVGVVLVLGITAGALVAIEGYNFL
Mb3530c|M.bovis_AF2122/97 TRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIAVQGYSSL
Rv3500c|M.tuberculosis_H37Rv TRYRKETVRLVAEMTLGAGALVMIGGTVGVAAFLTLASGGVIAVQGYSSL
MLBr_02588|M.leprae_Br4923 SRYRKETLRLIAQIGMGTGAMAVVGGTAAIVGFVTLSGSSLVAIQGFASL
* * .**:::: * *::. ***..:. .: : ..::.::.: *
Mflv_0011|M.gilvum_PYR-GCK DMLGLGPATGIISSLVNTRELAPIAASLAFATQAGCRFTAQLGSMRIAEE
Mvan_0958|M.vanbaalenii_PYR-1 DLLGLGPATGIISSLVNTRELAPIAASLAFATQAGCRFTAQLGSMRIAEE
MSMEG_1142|M.smegmatis_MC2_155 DLLGLGPATGIISSLVNTRELAPIAASLAFATQAGCRFTAQLGSMRIAEE
TH_3777|M.thermoresistible__bu DLLGLGPATGIISSLVNTRELAPIALSLAFATQAGCRFTAQLGSMRIAEE
MMAR_3863|M.marinum_M DLLGLGPATGLISSLVNTRELAPLMASLAFAMQAGCRFTAQLGSMRIAEE
MAV_0101|M.avium_104 NLLGLGPATGIISSLVNTRELAPIMASLAFAMQAGCRFTAQLGAMRIAEE
MAB_4600c|M.abscessus_ATCC_199 NIIGLGPATGFISSLVSTRELAPVMAALAFAMQAGCRFTAQLGAQRINEE
MUL_4920|M.ulcerans_Agy99 NMMGIGPATGVVSSLVTTRELAPIMAALGFAVQAGCRFTTQIGAMRVAEE
Mb3530c|M.bovis_AF2122/97 GDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLGAMRVSEE
Rv3500c|M.tuberculosis_H37Rv GDIGIEALTGFLSAFLNVRVVAPVIAGIALAATIGAGATAQLGAMRVSEE
MLBr_02588|M.leprae_Br4923 GAIGVEAFTGFFAALINVRIAAPVITGIVMAATVGAGATAELGAMRISEE
. :*: . **..::::..* **: .: :* *. *:::*: *: **
Mflv_0011|M.gilvum_PYR-GCK IDALESLGIRPIPYLVTTRLMASVIAVIPLYVVCLAVSYLTTQAVVMVIS
Mvan_0958|M.vanbaalenii_PYR-1 IDALESLGIRPIPYLVTTRLMASVVAVIPLYVLCLAVSYLTTQIVVQIIS
MSMEG_1142|M.smegmatis_MC2_155 IDALDSIAIRPIPYLVTTRLMAAVVAVIPLYVMCLAVSYLTTQTVVFLIS
TH_3777|M.thermoresistible__bu IDALESLAIRPVPYLVTTRLMASVIAVIPLYVMCLAVSYLTTQVVVQIIS
MMAR_3863|M.marinum_M IDAMESIAIRPIPFLVTTRLVASIVAMIPLYAACLAIGYLTTQVVVGISS
MAV_0101|M.avium_104 IDALESLAIRPIPFLVTTRLMASVIAVIPLYIACLAVTYLTCQVVANIIS
MAB_4600c|M.abscessus_ATCC_199 IDALDALAIRPIPYLVTTRLLASTVAVVPLYLLCLVISYITCRLLVGISS
MUL_4920|M.ulcerans_Agy99 IDALNAMAIRPIPYLVTTRLLASAVAIIPLYIACLTISYLSCQLMVTFTT
Mb3530c|M.bovis_AF2122/97 IDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAARFTTVFVN
Rv3500c|M.tuberculosis_H37Rv IDAVECMAVHSVSYLVSTRLIAGLVAIIPLYSLSVLAAFFAARFTTVFVN
MLBr_02588|M.leprae_Br4923 IDALEVMSIKSISFLVTTRILAGLVVIVPLYAVAMIMAFLSPHIITTVLY
***:: :.::.:.:**:**::*. :.::*** .: ::: : . .
Mflv_0011|M.gilvum_PYR-GCK GGSTG-SYMHYFTLMLSGQDILYSVLKTVIFVWIASTVQCYYGFYASGGP
Mvan_0958|M.vanbaalenii_PYR-1 GGSAG-SYLHYFTLMLSGQDILYSVLKTVIFVWIASTIQCYYGFYASGGP
MSMEG_1142|M.smegmatis_MC2_155 GGSTG-SYLHYFTLMLSGQDILYSLLKTIIFVWIASTVQCYYGFYASGGP
TH_3777|M.thermoresistible__bu GGATG-PYLHYFNLMLSGQDILYSLLKAIVFVWIATTIQCYYGFYASGGP
MMAR_3863|M.marinum_M GGSTG-SYLHYFSLMLAGQDIFYSLLKTVIFVWIASTIQCYYGFYASGGP
MAV_0101|M.avium_104 GGSIG-PYLHYFTMMLSAKDIAYSVLKCVVFVWLSSTVQCYYGFYAAGGP
MAB_4600c|M.abscessus_ATCC_199 GGSIGGAYNHYFTMMLSGTDVVYSVIKAVVFVWIASTIQCYFGFNASGGP
MUL_4920|M.ulcerans_Agy99 HGSVG-PYLHYFTMLIDARDVGYSVIKAAVFVALASVVQCYYGFCAEGGP
Mb3530c|M.bovis_AF2122/97 GQSAG-LYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGYNASGGS
Rv3500c|M.tuberculosis_H37Rv GQSAG-LYDHYFNTFLIPSDLLWSFMQAIAMSIAVMLVHTYYGYNASGGS
MLBr_02588|M.leprae_Br4923 GQSNG-TYEHYFRTFLRPDDVFWSFLEAVIITAVVMITHCYYGYTANGGP
: * * *** :: *: :*.:: : : *:*: * **.
Mflv_0011|M.gilvum_PYR-GCK VGVGVAAGHAMRASITVVIMVNMLLTMALWSVDAGARFGG
Mvan_0958|M.vanbaalenii_PYR-1 VGVGVAAGHAMRASITVVIMVNMLLTMALWSVDAGARFGG
MSMEG_1142|M.smegmatis_MC2_155 VGVGVAAGHAMRASITVVIIVNMLLTMALWSVDSGARFGG
TH_3777|M.thermoresistible__bu EGVGVAAGHAMRASITVVIIVNMLLTMALWNIDAGARFGG
MMAR_3863|M.marinum_M EGVGVAAGHGMRASITVVIMVNMLITMALWGVDSGARFGG
MAV_0101|M.avium_104 EGVGVAAGHAMRASITVVIMVNMLLTMALWSIDAGARFGG
MAB_4600c|M.abscessus_ATCC_199 EGVGVAAGHAMRAAITVVIIVNMLLTMALWGVDAGARFGG
MUL_4920|M.ulcerans_Agy99 EGVGVAAGHAMRASITVVIIVNMVLTMALWSVDAGVRFGG
Mb3530c|M.bovis_AF2122/97 VGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
Rv3500c|M.tuberculosis_H37Rv VGVGVAVGQAVRTSLIVVVVITLFISLAVYGASGNFNLSG
MLBr_02588|M.leprae_Br4923 VGVGEAVGRSMRFSLVSVQVVVLSATLALYGVDPNFALTV
*** *.*:.:* :: * :: : ::*::. . . :