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ACASAILTAGAGVSAPPGTAERSAVFDVGLTASVQPAPGALLTQFLANQVQNCSLICPFVVQGAVQIPAS VLAAPATLVTRLRAGQPVVQALGLTGATVSGTANEIWTGLIRTDLDQVVPRTQFGTEVIAVGLVRIGEAA ITQPGGLPGALGQVRSDLFGALNNPPGPEPLPAVHTPLEAAAVRGTEVFWAVAFHGPEQLTLIVTRVPNA FLTTLGSTGNVGKAVQAAGEAVATTISESVAPVRDALTKPIPITPATAAKDEGKAPDVTAAHPRAPAASV ELVKTMAPQAKTPVVRLDPKSNRQASLPRPPALSSRPDPGSAAKIKQPNPMSGLGGAIKKAFGDVGAKKP AAPGKPAKTDRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4325c | - | - | 100% (363) | hypothetical protein MAB_4325c |
| M. abscessus ATCC 19977 | MAB_4293 | - | 8e-07 | 35.33% (150) | putative Fe-S oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2864c | infB | 2e-07 | 31.61% (155) | translation initiation factor IF-2 |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2839c | infB | 2e-07 | 31.61% (155) | translation initiation factor IF-2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0611 | - | 1e-05 | 27.53% (247) | iron-sulphur-binding reductase |
| M. avium 104 | MAV_2906 | - | 1e-06 | 28.10% (274) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_4575 | - | 2e-37 | 30.35% (369) | hypothetical protein MSMEG_4575 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4375 | - | 4e-05 | 24.40% (291) | hypothetical protein Mvan_4375 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2864c|M.bovis_AF2122/97 --------------------------------------------------
Rv2839c|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQPASGRTDDIGAR
Mb2864c|M.bovis_AF2122/97 ----------------MAAGKARVHELAKELGVTSKEVLARLSEQGEFVK
Rv2839c|M.tuberculosis_H37Rv ----------------MAAGKARVHELAKELGVTSKEVLARLSEQGEFVK
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M IWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLFVENF
Mb2864c|M.bovis_AF2122/97 SASSTVEAPVARRLRESFGGSKPAPAKGTAKSPGKGPDKSLDKAL-----
Rv2839c|M.tuberculosis_H37Rv SASSTVEAPVARRLRESFGGSKPAPAKGTAKSPGKGPDKSLDKAL-----
Mvan_4375|M.vanbaalenii_PYR-1 ----------------------------MASLPVAAPAGSAEAAM-----
MAB_4325c|M.abscessus_ATCC_199 --------------------MACASAILTAGAGVSAPPGTAERSA-----
MSMEG_4575|M.smegmatis_MC2_155 --------MYARAHSAVLSTIAAASVGAALVAPVVEPPPDLHLPR-----
MAV_2906|M.avium_104 -------------------------MDFGALPPEVNSGRMYGGAG-----
MMAR_0611|M.marinum_M SIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASRFYGS
.
Mb2864c|M.bovis_AF2122/97 ----------------------DAAIDMAAGNGKATAAPAKAADSGGAAI
Rv2839c|M.tuberculosis_H37Rv ----------------------DAAIDMAAGNGKATAAPAKAADSGGAAI
Mvan_4375|M.vanbaalenii_PYR-1 ----------------------VALSVSGSSSWFLAAGRSDGWLSTGSRA
MAB_4325c|M.abscessus_ATCC_199 ----------------------VFDVGLTASVQPAPGALLTQFLANQVQN
MSMEG_4575|M.smegmatis_MC2_155 ----------------------VVSAPVELTASPALGALPLAFLQNQAQY
MAV_2906|M.avium_104 ----------------------SGPLLAAAAAWDALGAELYSFAAAYTST
MMAR_0611|M.marinum_M HNSGAWLVLFMIFNVIWTYVLVRGSAVNNETLPYGKGAFLSQLFGAILRP
..
Mb2864c|M.bovis_AF2122/97 VSPTTPAAPEPPTAVPPSPQAPHPGMAPGARPGPVPKPGIRTPRVGNNPF
Rv2839c|M.tuberculosis_H37Rv VSPTTPAAPEPPTAVPPSPQAPHPGMAPGARPGPVPKPGIRTPRVGNNPF
Mvan_4375|M.vanbaalenii_PYR-1 SSSSGPSATSAWASVPASG---------SGAPGPVS-----AVCTGSSSA
MAB_4325c|M.abscessus_ATCC_199 CSLICPFVVQGAVQIPASVLA--------------------APATLVTRL
MSMEG_4575|M.smegmatis_MC2_155 CSVICPFIVQGLVSVPVGTAL--------------------SPLAFLDSL
MAV_2906|M.avium_104 IAGLTVGSWLGPAATSMSAAAAP------------------FIAWATTTA
MMAR_0611|M.marinum_M LGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVTFKRLPD
. . .
Mb2864c|M.bovis_AF2122/97 SSAQPADRPIPRPPAPRPGTARPGVPRPGASPGSMPPRPGGAVGGARPPR
Rv2839c|M.tuberculosis_H37Rv SSAQPADRPIPRPPAPRPGTARPGVPRPGASPGSMPPRPGGAVGGARPPR
Mvan_4375|M.vanbaalenii_PYR-1 CDCSTAAPMLRSAVSTDSAMTVPAATR-------------------RPAS
MAB_4325c|M.abscessus_ATCC_199 RAGQPVVQALGLTGATVSGTANEIWTG------------------LIRTD
MSMEG_4575|M.smegmatis_MC2_155 GTNGSLTRAIGAAAASVTGPLNDAAEG------------------IILND
MAV_2906|M.avium_104 GQAEQVATQARLAAAAYETAFAATVPP-------------------PVIA
MMAR_0611|M.marinum_M GLGPLLPVEADGKPVDFENPPDDAIFGRGKIEDFTWKGMLDFATCTECGR
Mb2864c|M.bovis_AF2122/97 PGAPRPGGRPGAPGAGRSDAGGGNYRGGGVGAAPGTGFRGRPGGGGGGRP
Rv2839c|M.tuberculosis_H37Rv PGAPRPGGRPGAPGAGRSDAGGGNYRGGGVGAAPGTGFRGRPGGGGGGRP
Mvan_4375|M.vanbaalenii_PYR-1 ARAAAPTARAGSPVAASSRAN---------------------------AS
MAB_4325c|M.abscessus_ATCC_199 LDQVVPRTQFGTEVIA---------------------------------V
MSMEG_4575|M.smegmatis_MC2_155 VDRVVPKAFNNLEISV---------------------------------V
MAV_2906|M.avium_104 ANRSLLMTLIATNILGQN-------------------------------T
MMAR_0611|M.marinum_M CQSQCPAWNTGKPLSPKLVIMDLR------------------DHWMAKAP
Mb2864c|M.bovis_AF2122/97 GQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPH-GNG
Rv2839c|M.tuberculosis_H37Rv GQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDSMQAPVVGGVRLPH-GNG
Mvan_4375|M.vanbaalenii_PYR-1 GVSNTADSTWLKAG------------KTTAATMLVASTTATCSTPR-GRT
MAB_4325c|M.abscessus_ATCC_199 GLVRIGEAAITQPGG-----------LPGALGQVRSDLFGALNNPP-GPE
MSMEG_4575|M.smegmatis_MC2_155 QLLRIGAALADPAT------------LPDAIDTARQTILDGLNQPLPGPG
MAV_2906|M.avium_104 AAIAAAEAEYAEMWAQD-----AAAMYAYAAASAAAAELTPFTEPPRTTE
MMAR_0611|M.marinum_M YILGEKTADPLEGLDLETAAEEGHHVPESGFGRVPGDGPEQAARPLVGTA
. *
Mb2864c|M.bovis_AF2122/97 ETIRLARGASLSDFADKIDANPAALVQALFNLGEMVTATQSVGDETLELL
Rv2839c|M.tuberculosis_H37Rv ETIRLARGASLSDFADKIDANPAALVQALFNLGEMVTATQSVGDETLELL
Mvan_4375|M.vanbaalenii_PYR-1 VGVGLAT-------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 PLPAVHT-------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 VPVPTETG------------------------------------------
MAV_2906|M.avium_104 SSAAARQS------------------------------------------
MMAR_0611|M.marinum_M EQGGVIDPDVLWSCVSCG--ACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mb2864c|M.bovis_AF2122/97 GSEMNYNVQVVSPEDEDRELLESFDLSYGEDEGGEEDLQVRPPVVTVMGH
Rv2839c|M.tuberculosis_H37Rv GSEMNYNVQVVSPEDEDRELLESFDLSYGEDEGGEEDLQVRPPVVTVMGH
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
Mb2864c|M.bovis_AF2122/97 VDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVAVDLDGSQRLITFIDT
Rv2839c|M.tuberculosis_H37Rv VDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVAVDLDGSQRLITFIDT
Mvan_4375|M.vanbaalenii_PYR-1 --------IGALRAANVSSRAVSSALTTPGSPSAAAGRTLSR--------
MAB_4325c|M.abscessus_ATCC_199 ----------PLEAAAVRGTEVFWAVAFHGP-------------------
MSMEG_4575|M.smegmatis_MC2_155 -------ARTLPEVVAVEAIKVFAAVAFQAG-------------------
MAV_2906|M.avium_104 --------AAVAQSAASDLPAQLSTLIDVTP-------------------
MMAR_0611|M.marinum_M YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
.
Mb2864c|M.bovis_AF2122/97 PGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVV
Rv2839c|M.tuberculosis_H37Rv PGHEAFTAMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVV
Mvan_4375|M.vanbaalenii_PYR-1 PTTPTWKAFSARGATMVPSARIAAWAAAFVGPVTDAAAAPNARSRSPDPE
MAB_4325c|M.abscessus_ATCC_199 ---EQLTLIVTR----VPNAFLTTLGSTGNVGKAVQAAGEAVATTISESV
MSMEG_4575|M.smegmatis_MC2_155 ---ELVLLGVPQTVDAAAQELARSGDPARALSAAVEQAGDVLRTASTIVT
MAV_2906|M.avium_104 ---TMLQGLATTPSAAAATPAASIIEAIYPITAALRPFFAAVTGAYSPIG
MMAR_0611|M.marinum_M GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
:
Mb2864c|M.bovis_AF2122/97 AVNKIDKEGADPAKIRGQLTEYGLVPEEFGGDTMFVDISAKQGTNIEALE
Rv2839c|M.tuberculosis_H37Rv AVNKIDKEGADPAKIRGQLTEYGLVPEEFGGDTMFVDISAKQGTNIEALE
Mvan_4375|M.vanbaalenii_PYR-1 AVTKVTG-------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 AP------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 DSLQTAATN-------------------------------------IHDA
MAV_2906|M.avium_104 AIILPGG-----------------------------------------WW
MMAR_0611|M.marinum_M SNYSVLHHTQLLNRLIRDKKLVPVTPVSQDVTYHDPCYLGRHNKVYEAPR
Mb2864c|M.bovis_AF2122/97 EAVLLTADAALDLRANPD-------------MEAQGVAIEAHLDRGRGPV
Rv2839c|M.tuberculosis_H37Rv EAVLLTADAALDLRANPD-------------MEAQGVAIEAHLDRGRGPV
Mvan_4375|M.vanbaalenii_PYR-1 ACTVVTAAVTAVSTSSGQ-------------MIAQ--------YRIWLPT
MAB_4325c|M.abscessus_ATCC_199 ----VRDALTKPIPITPA-------------TAAK--------DEGKAPD
MSMEG_4575|M.smegmatis_MC2_155 AGGSADRRFDEAAPAVAA-------------LTTAKADKPGLDTDSKVTD
MAV_2906|M.avium_104 LLSLQALGLAQNAPGVAE-------------LLGG--------GKAIAGG
MMAR_0611|M.marinum_M ELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALA
Mb2864c|M.bovis_AF2122/97 ATVLVQRGTLRVGDSVVAGDAYGRVRRMVDEHGEDVEVALPSRPVQVIGF
Rv2839c|M.tuberculosis_H37Rv ATVLVQRGTLRVGDSVVAGDAYGRVRRMVDEHGEDVEVALPSRPVQVIGF
Mvan_4375|M.vanbaalenii_PYR-1 KLVMSPPGGTVVAARWTSRDTPG---------GGGGEVAIGTTGSAAAAV
MAB_4325c|M.abscessus_ATCC_199 VTAAHPRAPAASVELVKT--------------------MAPQAKTPVVRL
MSMEG_4575|M.smegmatis_MC2_155 ATKDDPDVTTKATTAQPAS------------------VTEPDSAGKSTPS
MAV_2906|M.avium_104 LSPLAPLRGGYVSAVTPDAGG----------------VAGSMGRSTLVGS
MMAR_0611|M.marinum_M TNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGSLDREK
Mb2864c|M.bovis_AF2122/97 TSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSA
Rv2839c|M.tuberculosis_H37Rv TSVPGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSA
Mvan_4375|M.vanbaalenii_PYR-1 S--PRTATPLLMTWRRWSARFIGPPRSTVCR-----GHERRARSVHCGCV
MAB_4325c|M.abscessus_ATCC_199 D--PKSNRQASLPRPPALSSRPDPGSAAKIK--------QPNPMSGLGGA
MSMEG_4575|M.smegmatis_MC2_155 VTKPRPIRKAASDIGRAMKSLTGSPAKTQKQQK--SLSGKGSDAGDSGKS
MAV_2906|M.avium_104 LSVPPGWTTAAPVLRTVASVLPAASSATAAAMPASGGAVFGEMAAASLAG
MMAR_0611|M.marinum_M ATLPEKGTAAKEAEKRAKAAPKAAAPAAPAPAPAEAPAKAAEAPAAATAA
* :
Mb2864c|M.bovis_AF2122/97 LKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVVLRVIDRGVGGITET
Rv2839c|M.tuberculosis_H37Rv LKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVVLRVIDRGVGGITET
Mvan_4375|M.vanbaalenii_PYR-1 FKYSSTGICVVDAYPTGRMTSPAVEL------------------------
MAB_4325c|M.abscessus_ATCC_199 IKKAFGDVGAKKPAAPGKPAKTDRP-------------------------
MSMEG_4575|M.smegmatis_MC2_155 TEKSSNEKKSEKKSTEKSSEKKHKSGKHAA--------------------
MAV_2906|M.avium_104 RALAGAGVRTVGNGTTGAATAAAADGAATTATIIVVPAD-----------
MMAR_0611|M.marinum_M SPAAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGA
:
Mb2864c|M.bovis_AF2122/97 NVNLASASDAVIIGFNVRAEGKATELASREGVEIRYYSVIYQAIDEIEQA
Rv2839c|M.tuberculosis_H37Rv NVNLASASDAVIIGFNVRAEGKATELASREGVEIRYYSVIYQAIDEIEQA
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M KKPGAKKAAAPTGETKPAEAAAPAAPAAPVKGLGMASGAKRPGAKKAAPP
Mb2864c|M.bovis_AF2122/97 LRGLLKPIYEENQLGRAEIRALFRSSKVGLIAGCLVTSGVMRRNAKARLL
Rv2839c|M.tuberculosis_H37Rv LRGLLKPIYEENQLGRAEIRALFRSSKVGLIAGCLVTSGVMRRNAKARLL
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M AAAAPEAAATASAPEAAAAPAEPAAPAAPVKGLGIATGAKRPGAKKAPAR
Mb2864c|M.bovis_AF2122/97 RDNIVVAENLSIASLRREKDDVTEVRDGFECGLTLGYADIKEGDVIESYE
Rv2839c|M.tuberculosis_H37Rv RDNIVVAENLSIASLRREKDDVTEVRDGFECGLTLGYADIKEGDVIESYE
Mvan_4375|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4325c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_4575|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2906|M.avium_104 --------------------------------------------------
MMAR_0611|M.marinum_M AEAPAAAAPAQPEPEATPEPEPASKQDGEPTPPAAPAAPVKGLGMARGAR
Mb2864c|M.bovis_AF2122/97 LVQKERA
Rv2839c|M.tuberculosis_H37Rv LVQKERA
Mvan_4375|M.vanbaalenii_PYR-1 -------
MAB_4325c|M.abscessus_ATCC_199 -------
MSMEG_4575|M.smegmatis_MC2_155 -------
MAV_2906|M.avium_104 -------
MMAR_0611|M.marinum_M PPGKR--