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MKRDIRAQLDVDILEPSTLEFQVAVSPLTGAEVSEELSLELNGRRVEAQEVAGEHGNRIHRLPAERGNLK VSYTATILGQADEVPVEAADLSTYLRPSRYAEADKFFGFAAAEFGEHTDPAVLLEKVSSWVGARLTYSPG SSDPIDGAVDTLLSGAGVCRDYAHLVVALLRAVKVPARLVAVYAPGCDPMDFHAVAEAVVDNRWRVVDAT CLAPRQTMVRITTGRDAADTAFLDNHGGQIVLNESIVAAVVDGELPEDHIDHLVSMR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4306 | - | - | 100% (267) | putative transglutaminase-like protein |
| M. abscessus ATCC 19977 | MAB_1637 | - | 8e-13 | 31.34% (134) | transglutaminase-like |
| M. abscessus ATCC 19977 | MAB_2859c | - | 5e-05 | 30.92% (152) | transglutaminase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2432c | - | 1e-08 | 23.64% (165) | hypothetical protein Mb2432c |
| M. gilvum PYR-GCK | Mflv_1205 | - | 1e-110 | 71.85% (270) | transglutaminase domain-containing protein |
| M. tuberculosis H37Rv | Rv2409c | - | 1e-08 | 23.64% (165) | hypothetical protein Rv2409c |
| M. leprae Br4923 | MLBr_00607 | - | 2e-09 | 24.14% (145) | hypothetical protein MLBr_00607 |
| M. marinum M | MMAR_3730 | - | 5e-11 | 33.71% (89) | putative transglutaminase-like protein |
| M. avium 104 | MAV_1773 | - | 4e-13 | 29.08% (196) | hypothetical protein MAV_1773 |
| M. smegmatis MC2 155 | MSMEG_4567 | - | 1e-12 | 27.89% (190) | hypothetical protein MSMEG_4567 |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3673 | - | 3e-11 | 33.71% (89) | putative transglutaminase-like protein |
| M. vanbaalenii PYR-1 | Mvan_1043 | - | 6e-99 | 66.67% (267) | transglutaminase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3730|M.marinum_M ------MWRMRVVHSTGYAYEAPVTASFNEARLTPRSNSRQNVILN-RVE
MUL_3673|M.ulcerans_Agy99 ------MWRMRVVHSTGYAYEAPVTASFNEARLTPRSNSRQNVILN-RVE
Mb2432c|M.bovis_AF2122/97 ------MWRTRVVHTTGYVYQSPVTASYNEARLTPRSSSRQNLVLN-RVE
Rv2409c|M.tuberculosis_H37Rv ------MWRTRVVHTTGYVYQSPVTASYNEARLTPRSSSRQNLVLN-RVE
MLBr_00607|M.leprae_Br4923 ------MWRMRVVHSTGYVYESPATASFNEARLTPRSNTRQTVILN-RVE
MAV_1773|M.avium_104 ------MWRLRVVHTTGYAYQSPVTASYNEARLTPRSNNRQNVILN-RVE
MSMEG_4567|M.smegmatis_MC2_155 ------MWRLRVVHSTGYAYKSPVTASFNEVRLTPRSDSRQNVILN-RVE
Mflv_1205|M.gilvum_PYR-GCK MPAVPLLSRFGKKRPAVDLMKRDVGAELDVEITDPTTLEFQIAVAPQPGA
Mvan_1043|M.vanbaalenii_PYR-1 -------------------MKRVVGSALEVAVTAPTTLEFQIAVAPHPNA
MAB_4306|M.abscessus_ATCC_1997 -------------------MKRDIRAQLDVDILEPSTLEFQVAVSPLTGA
: : : * : * :
MMAR_3730|M.marinum_M TIPATRSYRYVDYWGTAVTAFDLHAPHTELTVTSSSVVETERPEPPEAKV
MUL_3673|M.ulcerans_Agy99 TIPATRSYRYVDYWGTAVTAFDLHAPHTELTVTSSSVVETERPEPPEAKV
Mb2432c|M.bovis_AF2122/97 TIPATRSYRYIDYWGTAVTAFDLHAPHTELTVTSSSVVETERPEPLAAKA
Rv2409c|M.tuberculosis_H37Rv TIPATRSYRYIDYWGTAVTAFDLHAPHTELTVTSSSVVETERPEPLAAKA
MLBr_00607|M.leprae_Br4923 TIPATRSYRYIDYWGTVVTAFDLRAPHTELTVTSSSVVETESLEPSVSRI
MAV_1773|M.avium_104 TIPATRSYRYIDYWGTAVTAFDLHAPHTDLTVMSSSVVETERAERPATEL
MSMEG_4567|M.smegmatis_MC2_155 TVPATRSYRYVDYWGTAVTAFDLHAPHAELEVTSSSVVETEVGEKPEEPV
Mflv_1205|M.gilvum_PYR-GCK EVTESLSFVLDGREIPLSEIHEISGDHGNRIHKLEAPVGNLKVSYSATVI
Mvan_1043|M.vanbaalenii_PYR-1 VVYESLSFVLDG---TPVQALEVSGTHGNRIHKLDVAGGTLEVDYAATVI
MAB_4306|M.abscessus_ATCC_1997 EVSEELSLELNG---RRVEAQEVAGEHGNRIHRLPAERGNLKVSYTATIL
: * . :: . * : . .
MMAR_3730|M.marinum_M TWEELESMAVIDRFDEVLRPTSYTPTSKRVAAVGRRIRKYHDPAEAVVAA
MUL_3673|M.ulcerans_Agy99 TWEELESMAVIDRFDEVLRPTSYTPTSKRVAAVGRRIRKYHDPAEAVVAA
Mb2432c|M.bovis_AF2122/97 TWADLQSTAVIDRFDEVLRPTPHTPASARVDAVGRRIRKCHEPSEAVVAA
Rv2409c|M.tuberculosis_H37Rv TWADLQSTAVIDRFDEVLRPTPHTPASARVDAVGRRIRKCHEPSEAVVAA
MLBr_00607|M.leprae_Br4923 TWTELQSMAVIDRFDEVLQPTAYTPVNTRVAAVGKRIAKNHEPRKAVVAA
MAV_1773|M.avium_104 GWGDLHSEAVIDRFDELLRPTGHVPASKRVASVAKKIAKSHDPAEAVVAV
MSMEG_4567|M.smegmatis_MC2_155 SWDDLRTEAVIDRFDEVLAPTHYTPCSKRIERVGRSIAKEHDPYEAVIAA
Mflv_1205|M.gilvum_PYR-GCK GQADPAPVRDLD-LSTYLRPSRYAEADKFFGFAGTEFGDIADSATILEKI
Mvan_1043|M.vanbaalenii_PYR-1 GQTDPAPVTEYD-LSMYLRPSRYAEADKFYGFAATEFGRYADSATLLEKV
MAB_4306|M.abscessus_ATCC_1997 GQADEVPVEAAD-LSTYLRPSRYAEADKFFGFAAAEFGEHTDPAVLLEKV
: . * :. * *: :. . .. : :. :
MMAR_3730|M.marinum_M ARWARSELDYLPGTTGVHSSGLDALEQGKGVCQDFAHLSLIVLRGMGIPA
MUL_3673|M.ulcerans_Agy99 ARWARSELDYLPGTTGVHSSGLDALEQGKGVCQDFAHLSLIVLRGMGIPA
Mb2432c|M.bovis_AF2122/97 ARWARSELDYIPGTTSVHSSGLDALEQGKGVCQDFVHLSLMVLRSMGIPC
Rv2409c|M.tuberculosis_H37Rv ARWARSELDYIPGTTSVHSSGLDALEQGKGVCQDFVHLSLMVLRSMGIPC
MLBr_00607|M.leprae_Br4923 ARWARSKLDYIPGTTGVHSSGLDALHQCRGVCQDFAHLTLIVLRSMGIPG
MAV_1773|M.avium_104 GDWVRGELEYLPGTTSVHSSGLDALKEGRGVCQDFVHLSLMLLRSMGIPS
MSMEG_4567|M.smegmatis_MC2_155 AQWVRSELDYVPGTTGVHSSGLDALREGKGVCQDFAHLSLIMLRGMGIPA
Mflv_1205|M.gilvum_PYR-GCK SSWVGARLNYVPGSSDPIDGAADTLLAGSGVCRDYAHLVVALLRAVNVPA
Mvan_1043|M.vanbaalenii_PYR-1 SAWVGSRLNYVPGSSDPIDGAVDTLLAGAGVCRDFAHLVVAMLRAVNVPA
MAB_4306|M.abscessus_ATCC_1997 SSWVGARLTYSPGSSDPIDGAVDTLLSGAGVCRDYAHLVVALLRAVKVPA
. *. ..* * **::. ... *:* ***:*:.** : :**.: :*
MMAR_3730|M.marinum_M RYVSGYLHPKRNAVVGKSVAGRSHAWIQAWTGGWWHYDPTNDTEISEQYI
MUL_3673|M.ulcerans_Agy99 RYVSGYLHPKRNAVVGKSVAGRSHAWIQAWTGGWWHYDPTNDTEISEQYI
Mb2432c|M.bovis_AF2122/97 RYVSGYLHPKRDAVVGKTVDGRSHAWVQAWTGGWWHYDPTNDNEITEQYI
Rv2409c|M.tuberculosis_H37Rv RYVSGYLHPKRDAVVGKTVDGRSHAWVQAWTGGWWHYDPTNDNEITEQYI
MLBr_00607|M.leprae_Br4923 RYVSGYLHPKRDAVVGKTVEGRSHAWIQAWTGGWWNYDPTNDVEITEQYI
MAV_1773|M.avium_104 HYVSGYLHPKRDAVVGDTVDGRSHAWIEAWTGAWWSYDPTNDAEITEQYV
MSMEG_4567|M.smegmatis_MC2_155 RYVSGYLHPTRGAAVGDTIDGQSHAWVQAWTGGWWDYDPTNDSEINEQYV
Mflv_1205|M.gilvum_PYR-GCK RLVSVYAPG--------CQPMDFHAVAEAFVDGQWRVVDATLLAPRQSLV
Mvan_1043|M.vanbaalenii_PYR-1 RVVSVYAPG--------LYPMDFHAVGEAFVDGAWRVVDGTLLAPRQTLV
MAB_4306|M.abscessus_ATCC_1997 RLVAVYAPG--------CDPMDFHAVAEAVVDNRWRVVDATCLAPRQTMV
: *: * ** :* .. * . : :
MMAR_3730|M.marinum_M SVGAGRDYSDVPPLKGIYSGLGVTDLDVDVEITRLA--------------
MUL_3673|M.ulcerans_Agy99 SVGAGRDYSDVPPLKGIYSGLGVTDLDVDVEITRLA--------------
Mb2432c|M.bovis_AF2122/97 SVGVGRDYTDVSPLKGIYSGEGVTDLDVVVEITRLA--------------
Rv2409c|M.tuberculosis_H37Rv SVGVGRDYTDVSPLKGIYSGEGVTDLDVVVEITRLA--------------
MLBr_00607|M.leprae_Br4923 SVGVGRDYTDVAPLKGIYSGRGATDLDVVVEITRLA--------------
MAV_1773|M.avium_104 GVGAGRDYADVSPLKGIYSGKGATDLDVIVEVTRLALPTEEPAAIRRNAW
MSMEG_4567|M.smegmatis_MC2_155 SVGVGRNYSDVAPLKGIYSGEGSTDLDVVVEITRLA--------------
Mflv_1205|M.gilvum_PYR-GCK RIATGRDAADTAWLDNHKGQITVNNMEVFATVDGDLPRDSIDQLVSIR--
Mvan_1043|M.vanbaalenii_PYR-1 RIATGRDAADTAFLDNHKGAITLEKLEVTAIVDGDLPTDDIGELMSIR--
MAB_4306|M.abscessus_ATCC_1997 RITTGRDAADTAFLDNHGGQIVLNESIVAAVVDGELPEDHIDHLVSMR--
: .**: :*.. *.. . . * . :
MMAR_3730|M.marinum_M --------------------------------------------------
MUL_3673|M.ulcerans_Agy99 --------------------------------------------------
Mb2432c|M.bovis_AF2122/97 --------------------------------------------------
Rv2409c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_00607|M.leprae_Br4923 --------------------------------------------------
MAV_1773|M.avium_104 TTPRAAPPGCRCCRCSASACWAAGSPSGSGWAASCRCRTARWPRWRPMFA
MSMEG_4567|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1205|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1043|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_4306|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_3730|M.marinum_M -------
MUL_3673|M.ulcerans_Agy99 -------
Mb2432c|M.bovis_AF2122/97 -------
Rv2409c|M.tuberculosis_H37Rv -------
MLBr_00607|M.leprae_Br4923 -------
MAV_1773|M.avium_104 PSRMPCG
MSMEG_4567|M.smegmatis_MC2_155 -------
Mflv_1205|M.gilvum_PYR-GCK -------
Mvan_1043|M.vanbaalenii_PYR-1 -------
MAB_4306|M.abscessus_ATCC_1997 -------