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M. abscessus ATCC 19977 MAB_3981c (-)

annotation: zinc metalloprotease
coordinates: 4026640 - 4028715
length: 691

RLSRSAGVAALVLTVSIAGCTRDQPTTQVAANTPIPTFDNAQLSMRFAACADLNGFVNAKWIAQATIPAD
KASYGSFDMLNDEARKVQHEIVDGAVSGLGTADHESVNYQVGLLYRAATDDAKLDAAGYDPIRPTLAAID
QIKTPEELAAFLAADGATGQHLVFGLEAGADYANATEQIGYVRADALGMPTKDYYTDPRYASVFDAYRAY
IASTFGLIGADQELAKARAEQVASLESALAAATLSPVQERDPANQYKLVTVAQADAVTPHFEWGAYLKAQ
GAPSDRSFSLAETEFFTAFDRLLTTTDLDTWKSYLTFHAVHRSADALSKAFRDNAFKYKSALTGTTAQKQ
RWEQGLEIVNTLVGPALGQLYVERMFSDRDKRSATEVVQNVKEALRKRIEAVDWMSPQTKLAAKRKWDKL
LLKVGFPDKNRDFSKLKLAGDNFYTDRAAALKFNYDFEMAKIGRPTDRSLWGMTPQTVNAQYDPTENSIT
IPAAILQAPFYDAKGDPAFNYGGIGAVIGHEFTHAFDDEGSQFDGEGNRVNWWTPNDREEFDKRANRLVE
QFNAYTPIPGRPDLHVDGRLTLGENIADLGGVNTAYDALVAELAKHNDAEKAKGIVGFNEKQRFFLNYAR
IWRDKQRPEDAITQLASDPHSPPALRINGVVPNVAPFAAEFGCLAGDPMVNSPDKFVKIW*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_3981c--100% (691)zinc metalloprotease
M. abscessus ATCC 19977MAB_4536-e-11737.54% (642) zinc metalloprotease

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0204c-1e-12339.08% (650) zinc metalloprotease
M. gilvum PYR-GCKMflv_0472-1e-12839.19% (643) neprilysin
M. tuberculosis H37RvRv0198c-1e-12339.08% (650) zinc metalloprotease
M. leprae Br4923MLBr_02613-1e-11737.13% (649) putative zinc metalloprotease
M. marinum MMMAR_0438-1e-11637.29% (649) zinc metalloprotease
M. avium 104MAV_4977-1e-12038.82% (644) peptidase family protein M13
M. smegmatis MC2 155MSMEG_0234-1e-12538.34% (673) metallopeptidase
M. thermoresistible (build 8)TH_2118-1e-13240.19% (642) PROBABLE ZINC METALLOPROTEASE
M. ulcerans Agy99MUL_1088-1e-11737.44% (649) zinc metalloprotease
M. vanbaalenii PYR-1Mvan_0184-1e-13039.38% (650) neprilysin

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0472|M.gilvum_PYR-GCK          ---------------------MTVEATSDTS---AKSGIDLRYVDADARP
Mvan_0184|M.vanbaalenii_PYR-1       ---------------------MTVEATRN-----LKSGIDLRYVDTDARP
MSMEG_0234|M.smegmatis_MC2_155      ---------------------MTVQATRGTADATGKSGIDLTHVDPRTRP
TH_2118|M.thermoresistible__bu      -----------------------------------------------VRP
Mb0204c|M.bovis_AF2122/97           ---------------------MT-LAIPS--------GIDLSHIDADARP
Rv0198c|M.tuberculosis_H37Rv        ---------------------MT-LAIPS--------GIDLSHIDADARP
MMAR_0438|M.marinum_M               ---------------------MTYAAVRS--------GIDLSHVDPDARP
MUL_1088|M.ulcerans_Agy99           ---------------------MTYAAVRS--------GIDLSHVDPDARP
MLBr_02613|M.leprae_Br4923          ---------------------MNIEAIRS--------GIDLSYVDANTRP
MAV_4977|M.avium_104                ---------------------MTNTAIRS--------GIDLSHVDDSIRP
MAB_3981c|M.abscessus_ATCC_199      MRLSRSAGVAALVLTVSIAGCTRDQPTTQVAANTPIPTFDNAQLSMRFAA
                                                                                     .

Mflv_0472|M.gilvum_PYR-GCK          QDDLFGHVNGRWLAEYQIPGDRATDGAFRTLYDRAEEQIRDLITEAA---
Mvan_0184|M.vanbaalenii_PYR-1       QDDLFGHVNGRWLAEYQIPADRATDGAFRTLHDRAEEQIRDLITEVA---
MSMEG_0234|M.smegmatis_MC2_155      QDDLFGHVNGRWLTEYEIPADRATDGAFRLLYDRAEEQIRDLITEAA---
TH_2118|M.thermoresistible__bu      QDDLFGHVNGRWLAEHEIPADRAADGAFRELYDRAEQQIRDLIEEAA---
Mb0204c|M.bovis_AF2122/97           QDDLFGHVNGRWLAEHEIPADRATDGAFRSLFDRAETQVRDLIIQAS---
Rv0198c|M.tuberculosis_H37Rv        QDDLFGHVNGRWLAEHEIPADRATDGAFRSLFDRAETQVRDLIIQAS---
MMAR_0438|M.marinum_M               QDDLFGHVNGRWLKEYDIPADRATDGAFRHLFDRAEEQVRELIIEAS---
MUL_1088|M.ulcerans_Agy99           QDDLFGHVNGRWLKEYDIPADRATDGAFRHLFDRAEEQVRELIIEAS---
MLBr_02613|M.leprae_Br4923          QDDLFGHVNGRWLYEYEIPADRSTDGAFRHLFDQTEEQVRDLITEASGTA
MAV_4977|M.avium_104                QDDLFGHVNGRWLAEYEIPADRATDGAFRQLYDRAEEQVRDLIVEAS--E
MAB_3981c|M.abscessus_ATCC_199      CADLNGFVNAKWIAQATIPADKASYGSFDMLNDEARKVQHEIVDGAVS--
                                      ** *.**.:*: :  **.*::: *:*  * *.:.   ::::  .    

Mflv_0472|M.gilvum_PYR-GCK          SAHAAEGTDQQR---------IGDLYASFMDEQTVRDRGLAPLLDELGAI
Mvan_0184|M.vanbaalenii_PYR-1       GSGAARGTDEQRSSGSIDASRIGDLYASFMDEDTVRARGLTPLRDELAAV
MSMEG_0234|M.smegmatis_MC2_155      ASGAADGTDEQR---------IGDLYASFMDTQTIAERGLQPLLDELALI
TH_2118|M.thermoresistible__bu      QAGAPAGTDQQR---------IGDLYASFMDEQTVNRLGVRPLLDELATI
Mb0204c|M.bovis_AF2122/97           QAGAAVGTDAQR---------IGDLYASFLDEEAVERAGVQPLHDELATI
Rv0198c|M.tuberculosis_H37Rv        QAGAAVGTDAQR---------IGDLYASFLDEEAVERAGVQPLHDELATI
MMAR_0438|M.marinum_M               QQGAATGTDEQR---------IGDLYASFLDEETVERVGLQPLHDEVTAI
MUL_1088|M.ulcerans_Agy99           QQGAATGTDEQR---------IGDLYASFLDEETVERVGLQPLHDEVTAI
MLBr_02613|M.leprae_Br4923          AAGETAEADAQR---------IGDLYASFLDEQTVERRGTQPLLEELALI
MAV_4977|M.avium_104                QGAAAGGDDAQR---------IGDLYASFLDEDTVQRRGLQPLLDELALI
MAB_3981c|M.abscessus_ATCC_199      GLGTADHESVNY--------QVGLLYRAATDDAKLDAAGYDPIRPTLAAI
                                        .   . :          :* ** :  *   :   *  *:   :  :

Mflv_0472|M.gilvum_PYR-GCK          DAAGSPDALAEVLGSLQRTGIGGATGLYVDTDSKNSTRYLLHLTQSGIGL
Mvan_0184|M.vanbaalenii_PYR-1       DAADTPEALARVLGALQRVGVGGGTGLYVDTDSKNSSRYLLHLSQSGIGL
MSMEG_0234|M.smegmatis_MC2_155      DAAPDADALAAVLGGLQRTGVGGGAGVYVDTDSKNSTRYLLHMGQSGIGL
TH_2118|M.thermoresistible__bu      DAAADRTELAAVLGALQRTGVGGGAGAYVNTDAKNSSRYLLYLNQSGLGL
Mb0204c|M.bovis_AF2122/97           DSAADATELAAALGTLQRAGVGGGIGVYVDTDSKDSTRYLVHFTQSGIGL
Rv0198c|M.tuberculosis_H37Rv        DSAADATELAAALGTLQRAGVGGGIGVYVDTDSKDSTRYLVHFTQSGIGL
MMAR_0438|M.marinum_M               DDAADRDALAAAIGALQRTGMGGGVGLYVDTDSKDSTRYLMHFSQSGIGL
MUL_1088|M.ulcerans_Agy99           DNAADRDALAAAIGALQRTGMGGGVGLYVDTDSKDSTRYLMHFSQSGIGL
MLBr_02613|M.leprae_Br4923          DNATDTSDLAAVLGALQRTGMGGGVEVYVDTDSKDSTRYLLHFSQSGIGL
MAV_4977|M.avium_104                DEAADAAALAAVMGALQRTGVGGGVALYVDTDAKNSARYLVHVTQSGIGL
MAB_3981c|M.abscessus_ATCC_199      DQIKTPEELAAFLAADGATGQHLVFGLEAGADYANATEQIGYVRADALGM
                                    *       **  :.    .*        ..:*  :::. : :.  ..:*:

Mflv_0472|M.gilvum_PYR-GCK          PDESYFREEQHAEILAAYPGHIAAMFGLVLGGD----PGEHAATAQRIVA
Mvan_0184|M.vanbaalenii_PYR-1       PDESYFREERHAEILAAYPGHIAAMFGLVYGGD----PDDHAATADRIVA
MSMEG_0234|M.smegmatis_MC2_155      PDESYFRDEQHAEILAGYPVHIAKMFGLIYGG-------DHTDTAARIVA
TH_2118|M.thermoresistible__bu      PDESYYRDEAHAEVLAAYPAHIARMFALVYRD------GDHRDTAERILA
Mb0204c|M.bovis_AF2122/97           PDESYYRDEQHAAVLAAYPGHIARMFGLVYGG----ESRDHAKTADRIVA
Rv0198c|M.tuberculosis_H37Rv        PDESYYRDEQHAAVLAAYPGHIARMFGLVYGG----ESRDHAKTADRIVA
MMAR_0438|M.marinum_M               PDESYFREERHAAVLAAYPGHIARMFSLVFGG----DSTDHADVAARIVA
MUL_1088|M.ulcerans_Agy99           PDESYFREERHAAVLAAYPGHIARMFSLVFGG----DSTDHADVAARIVA
MLBr_02613|M.leprae_Br4923          PDESYFHDDQHAEVLAAYPEHIARMFTLVYRGERYQDPRCHAKTAARIVA
MAV_4977|M.avium_104                PDESYFRDEQHAEVLAAYPGHIARMLRLVFGG----SADDHAETAARIVA
MAB_3981c|M.abscessus_ATCC_199      PTKDYYTDPRYASVFDAYRAYIASTFGLIGAD-----QELAKARAEQVAS
                                    * :.*: :  :* :: .*  :**  : *:  .            * :: :

Mflv_0472|M.gilvum_PYR-GCK          LETKLAAAHWDVVKRRDADLTYNLRTFAELTDESPGFDWTRWLGGLGADR
Mvan_0184|M.vanbaalenii_PYR-1       LETKIAAAHWDVVKRRDADLTYNLRTFAEVTDQAPGFDWPGWLAGLGGTA
MSMEG_0234|M.smegmatis_MC2_155      LESKIAAAHWDVVKRRDADLTYNLRRFADLPAEAPGFDWSGWVQGLGTTP
TH_2118|M.thermoresistible__bu      LETKLAAAHWDVVKRRDAELSYNLRTFTDLADEAPGFDWTGWITALGTTP
Mb0204c|M.bovis_AF2122/97           LETKLADAHWDVVKRRDADLGYNLRTFAQLQTEGAGFDWVSWVTALGSAP
Rv0198c|M.tuberculosis_H37Rv        LETKLADAHWDVVKRRDADLGYNLRTFAQLQTEGAGFDWVSWVTALGSAP
MMAR_0438|M.marinum_M               LEAKLAAAHWDVVKRRDAELTYNLRTFAELQTEGSGFDWTGWVTAVGTTP
MUL_1088|M.ulcerans_Agy99           LEAKLAAAHWDVVKRRDPELTYNLRTFAELQTEGSGFDWTGWVTAVGTTP
MLBr_02613|M.leprae_Br4923          LETKLADAHWDVVKRRDADLSYNLRTFAELQSDGVGFDWSAWVTALGNTP
MAV_4977|M.avium_104                LEAKLAAAHWDVVKRRDADLTYNLRTFADLRTEGSGFDWDGWLQALGATP
MAB_3981c|M.abscessus_ATCC_199      LESALAAATLSPVQERDPANQYKLVTVAQADAVTPHFEWGAYLKAQGAPS
                                    **: :* *  . *:.**.   *:*  .::       *:*  :: . *   

Mflv_0472|M.gilvum_PYR-GCK          DKAADVVVRQPDYLTAFASLWSGSSLEDWKDWLRWRVIHGRAFLLTDELI
Mvan_0184|M.vanbaalenii_PYR-1       EQAAEVVVRQPDYLTAFAGLWADESLEDWKNWLRWRVIHARAFLLTDELI
MSMEG_0234|M.smegmatis_MC2_155      DTVAELVVRQPDYLTAFAGLWASEDLEDWKAWARWRVIHARAGLLTDDLV
TH_2118|M.thermoresistible__bu      EQAAELVARQPDYLTAFAELWSSADLEDWKAWLRWRVIHARAFLLTDELV
Mb0204c|M.bovis_AF2122/97           DAMTELVVRQPDYLVTFASLWASVNVEDWKCWARWRLIRARAPWLTRALV
Rv0198c|M.tuberculosis_H37Rv        DAMTELVVRQPDYLVTFASLWASVNVEDWKCWARWRLIRARAPWLTRALV
MMAR_0438|M.marinum_M               AAVAELVVRQPDYLRTFASLWTSESLEDWKCWARWRLIRARAPWLTSDLV
MUL_1088|M.ulcerans_Agy99           AAVAELVVRQPDYLRTFASLWTSESLEDWKCWARWRLIRARAPWLTSDLV
MLBr_02613|M.leprae_Br4923          ESVTELVVRQPDYLTAFAALWETINLEDWKCWARWRLIRARAPWLTDDLV
MAV_4977|M.avium_104                DAVAELVVRQPDYLTAFAALWESLDLDEWKWWARWRVIRARAGWLTDELV
MAB_3981c|M.abscessus_ATCC_199      D--RSFSLAETEFFTAFDRLLTTTDLDTWKSYLTFHAVHRSADALSKAFR
                                        ..   :.::: :*  *    .:: ** :  :: ::  *  *:  : 

Mflv_0472|M.gilvum_PYR-GCK          AEDFSFYGKRLSGTEEIRDRWKRGVSVVEALMGEALGKLYVERHFPPQAK
Mvan_0184|M.vanbaalenii_PYR-1       AEDFSFYGRRLSGTEEIRERWKRGVSVVESLMGEALGRLYVERHFPPHAK
MSMEG_0234|M.smegmatis_MC2_155      AEDFAFYGRTLSGTEQIRDRWKRAVSVVENLMGDALGKLYVQRHFPPEAK
TH_2118|M.thermoresistible__bu      AEDFEFYGRTLSGTQEIRERWKRGVSVVENLMGFALGKLYVERHFPPEAK
Mb0204c|M.bovis_AF2122/97           AEDFEFYGRTLTGAQQLRDRWKRGVSLVENLMGDAVGKLYVQRHFPPDAK
Rv0198c|M.tuberculosis_H37Rv        AEDFEFYGRTLTGAQQLRDRWKRGVSLVENLMGDAVGKLYVQRHFPPDAK
MMAR_0438|M.marinum_M               AEDFEFYGRRLTGAEQIRDRWKRAVALVESLTGDAVGKLYVQRHFPPDAK
MUL_1088|M.ulcerans_Agy99           AEDFEFYGRRLTGAEQIRDRWKRAVALVESLTGDAVGKLYVQRHFPPDAK
MLBr_02613|M.leprae_Br4923          AADFDFYGRLLTGAEQIRNRWKRGVSLVENLMGDAVGKLYVQRHFPLHAK
MAV_4977|M.avium_104                AADFDFYGRLLTGAEQIRDRWKRAVSLVESLMGDAVGKLYVARHFPPGAK
MAB_3981c|M.abscessus_ATCC_199      DNAFKYKS-ALTGTTAQKQRWEQGLEIVNTLVGPALGQLYVERMFSDRDK
                                       * : .  *:*:   ::**::.: :*: * * *:*:*** * *.   *

Mflv_0472|M.gilvum_PYR-GCK          ARMDELVANLREAYRVSINTLDWMTPQTREKALVKLDKFTPKIGYPNTWR
Mvan_0184|M.vanbaalenii_PYR-1       ARMDELVDNLREAYRVSINSLDWMTPQTREKALVKLDKFTPKIGYPNKWR
MSMEG_0234|M.smegmatis_MC2_155      ARMDELVANLREAYRVSIDELDWMTPETRAKALAKLDKFTPKIGYPARWR
TH_2118|M.thermoresistible__bu      SRMDELVANLREAYRVSISQLDWMTPQTREKALAKLDKFTPKIGYPAKWR
Mb0204c|M.bovis_AF2122/97           SRIDTLVDNLQEAYRISISELDWMTPQTRQRALAKLNKFTAKVGYPIKWR
Rv0198c|M.tuberculosis_H37Rv        SRIDTLVDNLQEAYRISISELDWMTPQTRQRALAKLNKFTAKVGYPIKWR
MMAR_0438|M.marinum_M               DRVDKLVANLREAYRVSITDLDWMTPQTRERALTKLAKFTAKVGYPVRWR
MUL_1088|M.ulcerans_Agy99           DRVDKLVANLREAYRVSITDLDWMTPQTRERALTKLAKFTAKVGYPVRWR
MLBr_02613|M.leprae_Br4923          ARVDALADNLQQAYRISISELAWMTPQTRERALAKLTKFTAKVGYPKKWR
MAV_4977|M.avium_104                ARIDELVSNLRAAYRISISDLDWMTPQTRQRALAKLDKFTAKVGYPAKWR
MAB_3981c|M.abscessus_ATCC_199      RSATEVVQNVKEALRKRIEAVDWMSPQTKLAAKRKWDKLLLKVGFPDKNR
                                         :. *:: * *  *  : **:*:*:  *  *  *:  *:*:*   *

Mflv_0472|M.gilvum_PYR-GCK          DYSALVIERDDLYGNYRRGYALEYDRDLAKLGGPVDRDEWFMTPQTVNAY
Mvan_0184|M.vanbaalenii_PYR-1       DYSALVIARDDLYGNYQRGYALEYDRDLAKLGGPVDRDEWFMTPQTVNAY
MSMEG_0234|M.smegmatis_MC2_155      DYSAVVIKRDDLYGNYRRGYIVNSDRELAKLGGPVDRDEWFMTPQTVNAY
TH_2118|M.thermoresistible__bu      DYSALEIRRDDLYGNYRRGYAVEFDRDIAKLGGPVDRDEWFMTPQTVNAY
Mb0204c|M.bovis_AF2122/97           DYSKLAIDRDDLYGNVQRGYAVNHDRELAKLFGPVDRDEWFMTPQTVNAY
Rv0198c|M.tuberculosis_H37Rv        DYSKLAIDRDDLYGNVQRGYAVNHDRELAKLFGPVDRDEWFMTPQTVNAY
MMAR_0438|M.marinum_M               DYSKLVIDRGDLYGNFRRGYAVDHDRELAKLGGPVDHDEWFMTPQTVNAY
MUL_1088|M.ulcerans_Agy99           DYSKLVIDRGDLYGNFRRGYAVDHDRELAKLGGPVDHDEWFMTPQTVNAY
MLBr_02613|M.leprae_Br4923          DYSQLVIDRDDLYGNCQRGYAVNHDRELAKLGGPVDRDEWFMTPQTVNAY
MAV_4977|M.avium_104                DYSALVIDRGDLYGNYQRGYAVNHDRELAKLGGPVDRDEWFMTPQTVNAY
MAB_3981c|M.abscessus_ATCC_199      DFSKLKLAGDNFYTDRAAALKFNYDFEMAKIGRPTDRSLWGMTPQTVNAQ
                                    *:* : :  .::* :   .  .: * ::**:  *.*:. * ******** 

Mflv_0472|M.gilvum_PYR-GCK          YNPGMNEIVFPAAILQPPFFDADADDAANYGGIGAVIGHEIGHGFDDQGA
Mvan_0184|M.vanbaalenii_PYR-1       YNPGMNEIVFPAAILQPPFFDADADDAANYGGIGAVIGHEIGHGFDDQGA
MSMEG_0234|M.smegmatis_MC2_155      YNPGMNEIVFPAAILQPPFFDAEADDAANYGGIGAVIGHEIGHGFDDQGA
TH_2118|M.thermoresistible__bu      YNPGMNEIVFPAAILQPPFFDAEADDAANYGGIGAVIGHEIGHGFDDQGS
Mb0204c|M.bovis_AF2122/97           YNPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGA
Rv0198c|M.tuberculosis_H37Rv        YNPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVIGHEIGHGFDDQGA
MMAR_0438|M.marinum_M               YNPGMNEIVFPAAILQPPFFDAQADDAANYGGIGAVIGHEIGHGFDDQGA
MUL_1088|M.ulcerans_Agy99           YNPGMNEIVFPAAILQPPFFDAQADDAANYGGIGAVIGHEIGHGFDDQGA
MLBr_02613|M.leprae_Br4923          YNPGMNEIVFPAAILQPPFFDVEADDAVNYGGIGAVIGHEIGHGFDDQGA
MAV_4977|M.avium_104                YNPGMNEIVFPAAILQPPFFDAEADDAANYGGIGAVIGHEIGHGFDDQGA
MAB_3981c|M.abscessus_ATCC_199      YDPTENSITIPAAILQAPFYDAKGDPAFNYGGIGAVIGHEFTHAFDDEGS
                                    *:*  *.*.:******.**:* ..* * ************: *.***:*:

Mflv_0472|M.gilvum_PYR-GCK          KYDGDGNLVDWWTDEDRAEFGKRTTALIEQYEQFTPRGLEPS---HHVNG
Mvan_0184|M.vanbaalenii_PYR-1       KYDGDGNLVNWWTDQDRDEFGLRTKALIEQYEELVPRGLEPS---HHVNG
MSMEG_0234|M.smegmatis_MC2_155      KYDGDGNLVDWWTDADRTEFGARTKALIEQYEQFTPRGLDPS---HHVNG
TH_2118|M.thermoresistible__bu      KYDGDGNLVDWWTDEDRTEFEARAKALIEQYDAYSPRELSGE---HRVNG
Mb0204c|M.bovis_AF2122/97           KYDGDGNLVDWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQG
Rv0198c|M.tuberculosis_H37Rv        KYDGDGNLVDWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQG
MMAR_0438|M.marinum_M               KYDGDGNLVDWWTDADRTEFAHRTKALIDQYEAYVPRDLAASEGPPHVQG
MUL_1088|M.ulcerans_Agy99           KYDGDGNLVDWWTDADRTEFAHRTKALIDQYEAYVPRDLAASEGPPHVQG
MLBr_02613|M.leprae_Br4923          KYDGDGNLIDWWTDDDRTEFNTRTKALIEQYNVYTPRGLDDH----HVNG
MAV_4977|M.avium_104                KYDGDGNLVDWWTDADRTEFASRTKALIEQYDAYTPRGLPSG---YHVNG
MAB_3981c|M.abscessus_ATCC_199      QFDGEGNRVNWWTPNDREEFDKRANRLVEQFNAYTPIPGRPD---LHVDG
                                    ::**:** ::***  ** **  *:. *::*:.   *          :*:*

Mflv_0472|M.gilvum_PYR-GCK          AFTVGENIGDLGGLSIALLAYRLSLK----GEPAPVIDGLTGVQRVFYGW
Mvan_0184|M.vanbaalenii_PYR-1       AFTVGENIGDLGGLSIALLAYRLSLK----GEPAPVIDGLTGEQRVFFGW
MSMEG_0234|M.smegmatis_MC2_155      AFTVGENIGDLGGLSIALLAYKLSLK----GKEAPVIDGLTGVQRVFFGW
TH_2118|M.thermoresistible__bu      AFTVGENIGDLGGLSIALLAYRLSLG----GREAPVIDGLTGEQRVFFGW
Mb0204c|M.bovis_AF2122/97           AFTIGENIGDLGGLSIALLAYQLSLN----GNPAPVIDGLTGMQRVFFGW
Rv0198c|M.tuberculosis_H37Rv        AFTIGENIGDLGGLSIALLAYQLSLN----GNPAPVIDGLTGMQRVFFGW
MMAR_0438|M.marinum_M               AFTVGENIGDLGGLSIALLAYQLSLQ----GKRAPVIDGLTGVQRVFFGW
MUL_1088|M.ulcerans_Agy99           AFTVGENIGDLGGLSIALLAYQLSLQ----GKRAPVIDGLTGVQRVFFGW
MLBr_02613|M.leprae_Br4923          AFTVGENIGDLGGLSIALLAYQLSLN----GQSAPVIDGLTGVQRVFFGW
MAV_4977|M.avium_104                AFTVGENIGDLGGLSIALLAYQLSLN----GQPAPVIDGLSGVQRVFYGW
MAB_3981c|M.abscessus_ATCC_199      RLTLGENIADLGGVNTAYDALVAELAKHNDAEKAKGIVGFNEKQRFFLNY
                                     :*:****.****:. *  *   .*     .. *  * *:.  **.* .:

Mflv_0472|M.gilvum_PYR-GCK          AQVWRTKSREAEAIRRLAVDPHSPPEFRCNGVIRNMDAFYDAFDVDPEDA
Mvan_0184|M.vanbaalenii_PYR-1       AQVWRTKSREAEAIRRLAVDPHSPPEFRCNAVVRNMDAFYDAFEVDEDDE
MSMEG_0234|M.smegmatis_MC2_155      AQVWRTKSREAEAIRRLAVDPHSPPEFRCNGVVRNIDDFYEAFDVTENDE
TH_2118|M.thermoresistible__bu      AQVWRTKYRPEEAIRRLAVDPHSPPEFRCNGVVRNIDAFYEAFGVTESDE
Mb0204c|M.bovis_AF2122/97           AQIWRTKSRAAEAIRRLAVDPHSPPEFRCNGVVRNVDAFYQAFDVTEDDA
Rv0198c|M.tuberculosis_H37Rv        AQIWRTKSRAAEAIRRLAVDPHSPPEFRCNGVVRNVDAFYQAFDVTEDDA
MMAR_0438|M.marinum_M               AQVWRTKSRDAEAIRRLAVDPHSPPEFRCNGVVRNLDAFYDAFDVAEDDE
MUL_1088|M.ulcerans_Agy99           AQVWRTKSRDAEAIRRLAVDPHSPPEFRCNGVVRNLDAFYDAFDVAEDDE
MLBr_02613|M.leprae_Br4923          AQMWRSKSRDAETIRRLAVDPHSPPEFRCNGVIRNVDAFYDAFDVDEDDA
MAV_4977|M.avium_104                AQVWRTKSREAEAIRRLAVDPHSPPEFRCNGVIRNMDAFYDAFDGADEGA
MAB_3981c|M.abscessus_ATCC_199      ARIWRDKQRPEDAITQLASDPHSPPALRINGVVPNVAPFAAEFGCLAGDP
                                    *::** * *  ::* :** ****** :* *.*: *:  *   *     . 

Mflv_0472|M.gilvum_PYR-GCK          LYLEPQRRVHIWN
Mvan_0184|M.vanbaalenii_PYR-1       LYLEPQRRVHIWN
MSMEG_0234|M.smegmatis_MC2_155      LFLEPERRVRIWN
TH_2118|M.thermoresistible__bu      LYLEPERRVRIWN
Mb0204c|M.bovis_AF2122/97           LFLDPQRRVRIWN
Rv0198c|M.tuberculosis_H37Rv        LFLDPQRRVRIWN
MMAR_0438|M.marinum_M               LFLTPQSRVRIWN
MUL_1088|M.ulcerans_Agy99           LFLTPQSRVRIWN
MLBr_02613|M.leprae_Br4923          LFLEPQLRVRIWN
MAV_4977|M.avium_104                LFLEPDRRVKIWN
MAB_3981c|M.abscessus_ATCC_199      MVNSPDKFVKIW-
                                    :   *:  *:**