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M. tuberculosis H37Rv Rv0198c (-)

annotation: PROBABLE ZINC METALLOPROTEASE
coordinates: 234516 - 236507
length: 663

TLAIPSGIDLSHIDADARPQDDLFGHVNGRWLAEHEIPADRATDGAFRSLFDRAETQVRDLIIQASQAGA
AVGTDAQRIGDLYASFLDEEAVERAGVQPLHDELATIDSAADATELAAALGTLQRAGVGGGIGVYVDTDS
KDSTRYLVHFTQSGIGLPDESYYRDEQHAAVLAAYPGHIARMFGLVYGGESRDHAKTADRIVALETKLAD
AHWDVVKRRDADLGYNLRTFAQLQTEGAGFDWVSWVTALGSAPDAMTELVVRQPDYLVTFASLWASVNVE
DWKCWARWRLIRARAPWLTRALVAEDFEFYGRTLTGAQQLRDRWKRGVSLVENLMGDAVGKLYVQRHFPP
DAKSRIDTLVDNLQEAYRISISELDWMTPQTRQRALAKLNKFTAKVGYPIKWRDYSKLAIDRDDLYGNVQ
RGYAVNHDRELAKLFGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFDPQADEAANYGGIGAVI
GHEIGHGFDDQGAKYDGDGNLVDWWTDDDRTEFAARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTIGEN
IGDLGGLSIALLAYQLSLNGNPAPVIDGLTGMQRVFFGWAQIWRTKSRAAEAIRRLAVDPHSPPEFRCNG
VVRNVDAFYQAFDVTEDDALFLDPQRRVRIWN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0198c--100% (663)PROBABLE ZINC METALLOPROTEASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0204c-0.0100.00% (663) zinc metalloprotease
M. gilvum PYR-GCKMflv_0472-0.073.97% (657) neprilysin
M. leprae Br4923MLBr_02613-0.080.96% (667) putative zinc metalloprotease
M. abscessus ATCC 19977MAB_4536-0.070.78% (657) zinc metalloprotease
M. marinum MMMAR_0438-0.082.73% (660) zinc metalloprotease
M. avium 104MAV_4977-0.080.48% (661) peptidase family protein M13
M. smegmatis MC2 155MSMEG_0234-0.077.02% (657) metallopeptidase
M. thermoresistible (build 8)TH_2118-0.076.90% (645) PROBABLE ZINC METALLOPROTEASE
M. ulcerans Agy99MUL_1088-0.082.58% (660) zinc metalloprotease
M. vanbaalenii PYR-1Mvan_0184-0.072.73% (671) neprilysin

CLUSTAL 2.0.9 multiple sequence alignment


Rv0198c|M.tuberculosis_H37Rv        -MTLAIPS--------GIDLSHIDADARPQDDLFGHVNGRWLAEHEIPAD
Mb0204c|M.bovis_AF2122/97           -MTLAIPS--------GIDLSHIDADARPQDDLFGHVNGRWLAEHEIPAD
MLBr_02613|M.leprae_Br4923          MNIEAIRS--------GIDLSYVDANTRPQDDLFGHVNGRWLYEYEIPAD
MMAR_0438|M.marinum_M               MTYAAVRS--------GIDLSHVDPDARPQDDLFGHVNGRWLKEYDIPAD
MUL_1088|M.ulcerans_Agy99           MTYAAVRS--------GIDLSHVDPDARPQDDLFGHVNGRWLKEYDIPAD
MAV_4977|M.avium_104                MTNTAIRS--------GIDLSHVDDSIRPQDDLFGHVNGRWLAEYEIPAD
MSMEG_0234|M.smegmatis_MC2_155      MTVQATRGTADATGKSGIDLTHVDPRTRPQDDLFGHVNGRWLTEYEIPAD
TH_2118|M.thermoresistible__bu      --------------------------VRPQDDLFGHVNGRWLAEHEIPAD
Mflv_0472|M.gilvum_PYR-GCK          MTVEATSDTS---AKSGIDLRYVDADARPQDDLFGHVNGRWLAEYQIPGD
Mvan_0184|M.vanbaalenii_PYR-1       MTVEATRN-----LKSGIDLRYVDTDARPQDDLFGHVNGRWLAEYQIPAD
MAB_4536|M.abscessus_ATCC_1997      MTTESVLP------KSGIDLSHRDESIRPQDDLFGHVNGRWLAEYAIPAD
                                                               *************** *: **.*

Rv0198c|M.tuberculosis_H37Rv        RATDGAFRSLFDRAETQVRDLIIQAS---QAGAAVGTDAQR---------
Mb0204c|M.bovis_AF2122/97           RATDGAFRSLFDRAETQVRDLIIQAS---QAGAAVGTDAQR---------
MLBr_02613|M.leprae_Br4923          RSTDGAFRHLFDQTEEQVRDLITEASGTAAAGETAEADAQR---------
MMAR_0438|M.marinum_M               RATDGAFRHLFDRAEEQVRELIIEAS---QQGAATGTDEQR---------
MUL_1088|M.ulcerans_Agy99           RATDGAFRHLFDRAEEQVRELIIEAS---QQGAATGTDEQR---------
MAV_4977|M.avium_104                RATDGAFRQLYDRAEEQVRDLIVEAS--EQGAAAGGDDAQR---------
MSMEG_0234|M.smegmatis_MC2_155      RATDGAFRLLYDRAEEQIRDLITEAA---ASGAADGTDEQR---------
TH_2118|M.thermoresistible__bu      RAADGAFRELYDRAEQQIRDLIEEAA---QAGAPAGTDQQR---------
Mflv_0472|M.gilvum_PYR-GCK          RATDGAFRTLYDRAEEQIRDLITEAA---SAHAAEGTDQQR---------
Mvan_0184|M.vanbaalenii_PYR-1       RATDGAFRTLHDRAEEQIRDLITEVA---GSGAARGTDEQRSSGSIDASR
MAB_4536|M.abscessus_ATCC_1997      RAVDGAFRTLFDRAEEQVREIITEAA---DSNAAEGTESQK---------
                                    *:.***** *.*::* *:*::* :.:       .   : *:         

Rv0198c|M.tuberculosis_H37Rv        IGDLYASFLDEEAVERAGVQPLHDELATIDSAADATELAAALGTLQRAGV
Mb0204c|M.bovis_AF2122/97           IGDLYASFLDEEAVERAGVQPLHDELATIDSAADATELAAALGTLQRAGV
MLBr_02613|M.leprae_Br4923          IGDLYASFLDEQTVERRGTQPLLEELALIDNATDTSDLAAVLGALQRTGM
MMAR_0438|M.marinum_M               IGDLYASFLDEETVERVGLQPLHDEVTAIDDAADRDALAAAIGALQRTGM
MUL_1088|M.ulcerans_Agy99           IGDLYASFLDEETVERVGLQPLHDEVTAIDNAADRDALAAAIGALQRTGM
MAV_4977|M.avium_104                IGDLYASFLDEDTVQRRGLQPLLDELALIDEAADAAALAAVMGALQRTGV
MSMEG_0234|M.smegmatis_MC2_155      IGDLYASFMDTQTIAERGLQPLLDELALIDAAPDADALAAVLGGLQRTGV
TH_2118|M.thermoresistible__bu      IGDLYASFMDEQTVNRLGVRPLLDELATIDAAADRTELAAVLGALQRTGV
Mflv_0472|M.gilvum_PYR-GCK          IGDLYASFMDEQTVRDRGLAPLLDELGAIDAAGSPDALAEVLGSLQRTGI
Mvan_0184|M.vanbaalenii_PYR-1       IGDLYASFMDEDTVRARGLTPLRDELAAVDAADTPEALARVLGALQRVGV
MAB_4536|M.abscessus_ATCC_1997      IGDLFASFMDTETVSGLGLTPLQQELDLIASASDTTALAAVMGVLQRAGV
                                    ****:***:* :::   *  ** :*:  :  *     ** .:* ***.*:

Rv0198c|M.tuberculosis_H37Rv        GGGIGVYVDTDSKDSTRYLVHFTQSGIGLPDESYYRDEQHAAVLAAYPGH
Mb0204c|M.bovis_AF2122/97           GGGIGVYVDTDSKDSTRYLVHFTQSGIGLPDESYYRDEQHAAVLAAYPGH
MLBr_02613|M.leprae_Br4923          GGGVEVYVDTDSKDSTRYLLHFSQSGIGLPDESYFHDDQHAEVLAAYPEH
MMAR_0438|M.marinum_M               GGGVGLYVDTDSKDSTRYLMHFSQSGIGLPDESYFREERHAAVLAAYPGH
MUL_1088|M.ulcerans_Agy99           GGGVGLYVDTDSKDSTRYLMHFSQSGIGLPDESYFREERHAAVLAAYPGH
MAV_4977|M.avium_104                GGGVALYVDTDAKNSARYLVHVTQSGIGLPDESYFRDEQHAEVLAAYPGH
MSMEG_0234|M.smegmatis_MC2_155      GGGAGVYVDTDSKNSTRYLLHMGQSGIGLPDESYFRDEQHAEILAGYPVH
TH_2118|M.thermoresistible__bu      GGGAGAYVNTDAKNSSRYLLYLNQSGLGLPDESYYRDEAHAEVLAAYPAH
Mflv_0472|M.gilvum_PYR-GCK          GGATGLYVDTDSKNSTRYLLHLTQSGIGLPDESYFREEQHAEILAAYPGH
Mvan_0184|M.vanbaalenii_PYR-1       GGGTGLYVDTDSKNSSRYLLHLSQSGIGLPDESYFREERHAEILAAYPGH
MAB_4536|M.abscessus_ATCC_1997      GSGVGCYVDTDAKDSSRYLLHVSQSGLGLPDESYYREEQHAATRDAYRTH
                                    *..   **:**:*:*:***::. ***:*******:::: **    .*  *

Rv0198c|M.tuberculosis_H37Rv        IARMFGLVYGGE----SRDHAKTADRIVALETKLADAHWDVVKRRDADLG
Mb0204c|M.bovis_AF2122/97           IARMFGLVYGGE----SRDHAKTADRIVALETKLADAHWDVVKRRDADLG
MLBr_02613|M.leprae_Br4923          IARMFTLVYRGERYQDPRCHAKTAARIVALETKLADAHWDVVKRRDADLS
MMAR_0438|M.marinum_M               IARMFSLVFGGD----STDHADVAARIVALEAKLAAAHWDVVKRRDAELT
MUL_1088|M.ulcerans_Agy99           IARMFSLVFGGD----STDHADVAARIVALEAKLAAAHWDVVKRRDPELT
MAV_4977|M.avium_104                IARMLRLVFGGS----ADDHAETAARIVALEAKLAAAHWDVVKRRDADLT
MSMEG_0234|M.smegmatis_MC2_155      IAKMFGLIYG-------GDHTDTAARIVALESKIAAAHWDVVKRRDADLT
TH_2118|M.thermoresistible__bu      IARMFALVYRD------GDHRDTAERILALETKLAAAHWDVVKRRDAELS
Mflv_0472|M.gilvum_PYR-GCK          IAAMFGLVLGGD----PGEHAATAQRIVALETKLAAAHWDVVKRRDADLT
Mvan_0184|M.vanbaalenii_PYR-1       IAAMFGLVYGGD----PDDHAATADRIVALETKIAAAHWDVVKRRDADLT
MAB_4536|M.abscessus_ATCC_1997      IAAMFTLVYGDG------DHADTAGKIVALETKIAAAHWDVVKRRDAELS
                                    ** *: *:           *  .* :*:***:*:* **********.:* 

Rv0198c|M.tuberculosis_H37Rv        YNLRTFAQLQTEGAGFDWVSWVTALGSAPDAMTELVVRQPDYLVTFASLW
Mb0204c|M.bovis_AF2122/97           YNLRTFAQLQTEGAGFDWVSWVTALGSAPDAMTELVVRQPDYLVTFASLW
MLBr_02613|M.leprae_Br4923          YNLRTFAELQSDGVGFDWSAWVTALGNTPESVTELVVRQPDYLTAFAALW
MMAR_0438|M.marinum_M               YNLRTFAELQTEGSGFDWTGWVTAVGTTPAAVAELVVRQPDYLRTFASLW
MUL_1088|M.ulcerans_Agy99           YNLRTFAELQTEGSGFDWTGWVTAVGTTPAAVAELVVRQPDYLRTFASLW
MAV_4977|M.avium_104                YNLRTFADLRTEGSGFDWDGWLQALGATPDAVAELVVRQPDYLTAFAALW
MSMEG_0234|M.smegmatis_MC2_155      YNLRRFADLPAEAPGFDWSGWVQGLGTTPDTVAELVVRQPDYLTAFAGLW
TH_2118|M.thermoresistible__bu      YNLRTFTDLADEAPGFDWTGWITALGTTPEQAAELVARQPDYLTAFAELW
Mflv_0472|M.gilvum_PYR-GCK          YNLRTFAELTDESPGFDWTRWLGGLGADRDKAADVVVRQPDYLTAFASLW
Mvan_0184|M.vanbaalenii_PYR-1       YNLRTFAEVTDQAPGFDWPGWLAGLGGTAEQAAEVVVRQPDYLTAFAGLW
MAB_4536|M.abscessus_ATCC_1997      YNLLRFADLEQTAPGFDWSGWLSALGAGAGQVTELVVRQPDYLTTFGRLW
                                    ***  *:::   . ****  *: .:*      :::*.****** :*. **

Rv0198c|M.tuberculosis_H37Rv        ASVNVEDWKCWARWRLIRARAPWLTRALVAEDFEFYGRTLTGAQQLRDRW
Mb0204c|M.bovis_AF2122/97           ASVNVEDWKCWARWRLIRARAPWLTRALVAEDFEFYGRTLTGAQQLRDRW
MLBr_02613|M.leprae_Br4923          ETINLEDWKCWARWRLIRARAPWLTDDLVAADFDFYGRLLTGAEQIRNRW
MMAR_0438|M.marinum_M               TSESLEDWKCWARWRLIRARAPWLTSDLVAEDFEFYGRRLTGAEQIRDRW
MUL_1088|M.ulcerans_Agy99           TSESLEDWKCWARWRLIRARAPWLTSDLVAEDFEFYGRRLTGAEQIRDRW
MAV_4977|M.avium_104                ESLDLDEWKWWARWRVIRARAGWLTDELVAADFDFYGRLLTGAEQIRDRW
MSMEG_0234|M.smegmatis_MC2_155      ASEDLEDWKAWARWRVIHARAGLLTDDLVAEDFAFYGRTLSGTEQIRDRW
TH_2118|M.thermoresistible__bu      SSADLEDWKAWLRWRVIHARAFLLTDELVAEDFEFYGRTLSGTQEIRERW
Mflv_0472|M.gilvum_PYR-GCK          SGSSLEDWKDWLRWRVIHGRAFLLTDELIAEDFSFYGKRLSGTEEIRDRW
Mvan_0184|M.vanbaalenii_PYR-1       ADESLEDWKNWLRWRVIHARAFLLTDELIAEDFSFYGRRLSGTEEIRERW
MAB_4536|M.abscessus_ATCC_1997      ATEPLSDWKLWASWRLICARAPYLTDPLVNENFDFYGRTLSGTEQIRDRW
                                        :.:** *  **:* .**  **  *:  :* ***: *:*::::*:**

Rv0198c|M.tuberculosis_H37Rv        KRGVSLVENLMGDAVGKLYVQRHFPPDAKSRIDTLVDNLQEAYRISISEL
Mb0204c|M.bovis_AF2122/97           KRGVSLVENLMGDAVGKLYVQRHFPPDAKSRIDTLVDNLQEAYRISISEL
MLBr_02613|M.leprae_Br4923          KRGVSLVENLMGDAVGKLYVQRHFPLHAKARVDALADNLQQAYRISISEL
MMAR_0438|M.marinum_M               KRAVALVESLTGDAVGKLYVQRHFPPDAKDRVDKLVANLREAYRVSITDL
MUL_1088|M.ulcerans_Agy99           KRAVALVESLTGDAVGKLYVQRHFPPDAKDRVDKLVANLREAYRVSITDL
MAV_4977|M.avium_104                KRAVSLVESLMGDAVGKLYVARHFPPGAKARIDELVSNLRAAYRISISDL
MSMEG_0234|M.smegmatis_MC2_155      KRAVSVVENLMGDALGKLYVQRHFPPEAKARMDELVANLREAYRVSIDEL
TH_2118|M.thermoresistible__bu      KRGVSVVENLMGFALGKLYVERHFPPEAKSRMDELVANLREAYRVSISQL
Mflv_0472|M.gilvum_PYR-GCK          KRGVSVVEALMGEALGKLYVERHFPPQAKARMDELVANLREAYRVSINTL
Mvan_0184|M.vanbaalenii_PYR-1       KRGVSVVESLMGEALGRLYVERHFPPHAKARMDELVDNLREAYRVSINSL
MAB_4536|M.abscessus_ATCC_1997      KRGVAVVESLLGEAVGQLYVARHFPPNAKARMEILVDNLREAYRVSITDL
                                    **.*::** * * *:*:*** ****  ** *:: *. **: ***:**  *

Rv0198c|M.tuberculosis_H37Rv        DWMTPQTRQRALAKLNKFTAKVGYPIKWRDYSKLAIDRDDLYGNVQRGYA
Mb0204c|M.bovis_AF2122/97           DWMTPQTRQRALAKLNKFTAKVGYPIKWRDYSKLAIDRDDLYGNVQRGYA
MLBr_02613|M.leprae_Br4923          AWMTPQTRERALAKLTKFTAKVGYPKKWRDYSQLVIDRDDLYGNCQRGYA
MMAR_0438|M.marinum_M               DWMTPQTRERALTKLAKFTAKVGYPVRWRDYSKLVIDRGDLYGNFRRGYA
MUL_1088|M.ulcerans_Agy99           DWMTPQTRERALTKLAKFTAKVGYPVRWRDYSKLVIDRGDLYGNFRRGYA
MAV_4977|M.avium_104                DWMTPQTRQRALAKLDKFTAKVGYPAKWRDYSALVIDRGDLYGNYQRGYA
MSMEG_0234|M.smegmatis_MC2_155      DWMTPETRAKALAKLDKFTPKIGYPARWRDYSAVVIKRDDLYGNYRRGYI
TH_2118|M.thermoresistible__bu      DWMTPQTREKALAKLDKFTPKIGYPAKWRDYSALEIRRDDLYGNYRRGYA
Mflv_0472|M.gilvum_PYR-GCK          DWMTPQTREKALVKLDKFTPKIGYPNTWRDYSALVIERDDLYGNYRRGYA
Mvan_0184|M.vanbaalenii_PYR-1       DWMTPQTREKALVKLDKFTPKIGYPNKWRDYSALVIARDDLYGNYQRGYA
MAB_4536|M.abscessus_ATCC_1997      EWMTPQTRERALQKLDKFTPKIGYPATWRDYSTITIRRDDLLGNVRRATA
                                     ****:** :** ** ***.*:***  ***** : * *.** ** :*.  

Rv0198c|M.tuberculosis_H37Rv        VNHDRELAKLFGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
Mb0204c|M.bovis_AF2122/97           VNHDRELAKLFGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MLBr_02613|M.leprae_Br4923          VNHDRELAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MMAR_0438|M.marinum_M               VDHDRELAKLGGPVDHDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MUL_1088|M.ulcerans_Agy99           VDHDRELAKLGGPVDHDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MAV_4977|M.avium_104                VNHDRELAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MSMEG_0234|M.smegmatis_MC2_155      VNSDRELAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
TH_2118|M.thermoresistible__bu      VEFDRDIAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
Mflv_0472|M.gilvum_PYR-GCK          LEYDRDLAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
Mvan_0184|M.vanbaalenii_PYR-1       LEYDRDLAKLGGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
MAB_4536|M.abscessus_ATCC_1997      AECDRGLAKLAGPVDRDEWFMTPQTVNAYYNPGMNEIVFPAAILQPPFFD
                                     : ** :*** ****:**********************************

Rv0198c|M.tuberculosis_H37Rv        PQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDDDRTEFA
Mb0204c|M.bovis_AF2122/97           PQADEAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDDDRTEFA
MLBr_02613|M.leprae_Br4923          VEADDAVNYGGIGAVIGHEIGHGFDDQGAKYDGDGNLIDWWTDDDRTEFN
MMAR_0438|M.marinum_M               AQADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDADRTEFA
MUL_1088|M.ulcerans_Agy99           AQADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDADRTEFA
MAV_4977|M.avium_104                AEADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDADRTEFA
MSMEG_0234|M.smegmatis_MC2_155      AEADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDADRTEFG
TH_2118|M.thermoresistible__bu      AEADDAANYGGIGAVIGHEIGHGFDDQGSKYDGDGNLVDWWTDEDRTEFE
Mflv_0472|M.gilvum_PYR-GCK          ADADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVDWWTDEDRAEFG
Mvan_0184|M.vanbaalenii_PYR-1       ADADDAANYGGIGAVIGHEIGHGFDDQGAKYDGDGNLVNWWTDQDRDEFG
MAB_4536|M.abscessus_ATCC_1997      ADADDAANYGGIGAVIGHEIGHGFDDQGSKYDGDGNLVNWWTDTDRDEFG
                                     :**:*.*********************:********::**** ** ** 

Rv0198c|M.tuberculosis_H37Rv        ARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTIGENIGDLGGLSIALLAY
Mb0204c|M.bovis_AF2122/97           ARTKALIEQYHAYTPRDLVDHPGPPHVQGAFTIGENIGDLGGLSIALLAY
MLBr_02613|M.leprae_Br4923          TRTKALIEQYNVYTPRGLDDH----HVNGAFTVGENIGDLGGLSIALLAY
MMAR_0438|M.marinum_M               HRTKALIDQYEAYVPRDLAASEGPPHVQGAFTVGENIGDLGGLSIALLAY
MUL_1088|M.ulcerans_Agy99           HRTKALIDQYEAYVPRDLAASEGPPHVQGAFTVGENIGDLGGLSIALLAY
MAV_4977|M.avium_104                SRTKALIEQYDAYTPRGLPSG---YHVNGAFTVGENIGDLGGLSIALLAY
MSMEG_0234|M.smegmatis_MC2_155      ARTKALIEQYEQFTPRGLDPS---HHVNGAFTVGENIGDLGGLSIALLAY
TH_2118|M.thermoresistible__bu      ARAKALIEQYDAYSPRELSGE---HRVNGAFTVGENIGDLGGLSIALLAY
Mflv_0472|M.gilvum_PYR-GCK          KRTTALIEQYEQFTPRGLEPS---HHVNGAFTVGENIGDLGGLSIALLAY
Mvan_0184|M.vanbaalenii_PYR-1       LRTKALIEQYEELVPRGLEPS---HHVNGAFTVGENIGDLGGLSIALLAY
MAB_4536|M.abscessus_ATCC_1997      VRTKALIKQYDEFVPRELSDQ----HVNGAFTVGENIGDLGGLSIALLAY
                                     *:.***.**.   ** *       :*:****:*****************

Rv0198c|M.tuberculosis_H37Rv        QLSLNGNPAPVIDGLTGMQRVFFGWAQIWRTKSRAAEAIRRLAVDPHSPP
Mb0204c|M.bovis_AF2122/97           QLSLNGNPAPVIDGLTGMQRVFFGWAQIWRTKSRAAEAIRRLAVDPHSPP
MLBr_02613|M.leprae_Br4923          QLSLNGQSAPVIDGLTGVQRVFFGWAQMWRSKSRDAETIRRLAVDPHSPP
MMAR_0438|M.marinum_M               QLSLQGKRAPVIDGLTGVQRVFFGWAQVWRTKSRDAEAIRRLAVDPHSPP
MUL_1088|M.ulcerans_Agy99           QLSLQGKRAPVIDGLTGVQRVFFGWAQVWRTKSRDAEAIRRLAVDPHSPP
MAV_4977|M.avium_104                QLSLNGQPAPVIDGLSGVQRVFYGWAQVWRTKSREAEAIRRLAVDPHSPP
MSMEG_0234|M.smegmatis_MC2_155      KLSLKGKEAPVIDGLTGVQRVFFGWAQVWRTKSREAEAIRRLAVDPHSPP
TH_2118|M.thermoresistible__bu      RLSLGGREAPVIDGLTGEQRVFFGWAQVWRTKYRPEEAIRRLAVDPHSPP
Mflv_0472|M.gilvum_PYR-GCK          RLSLKGEPAPVIDGLTGVQRVFYGWAQVWRTKSREAEAIRRLAVDPHSPP
Mvan_0184|M.vanbaalenii_PYR-1       RLSLKGEPAPVIDGLTGEQRVFFGWAQVWRTKSREAEAIRRLAVDPHSPP
MAB_4536|M.abscessus_ATCC_1997      EISLGGGAGPVIDGLTGVQRVFYGWAQVWRTKAREAEAIRRLSVDPHSPP
                                    .:** *  .******:* ****:****:**:* *  *:****:*******

Rv0198c|M.tuberculosis_H37Rv        EFRCNGVVRNVDAFYQAFDVTEDDALFLDPQRRVRIWN
Mb0204c|M.bovis_AF2122/97           EFRCNGVVRNVDAFYQAFDVTEDDALFLDPQRRVRIWN
MLBr_02613|M.leprae_Br4923          EFRCNGVIRNVDAFYDAFDVDEDDALFLEPQLRVRIWN
MMAR_0438|M.marinum_M               EFRCNGVVRNLDAFYDAFDVAEDDELFLTPQSRVRIWN
MUL_1088|M.ulcerans_Agy99           EFRCNGVVRNLDAFYDAFDVAEDDELFLTPQSRVRIWN
MAV_4977|M.avium_104                EFRCNGVIRNMDAFYDAFDGADEGALFLEPDRRVKIWN
MSMEG_0234|M.smegmatis_MC2_155      EFRCNGVVRNIDDFYEAFDVTENDELFLEPERRVRIWN
TH_2118|M.thermoresistible__bu      EFRCNGVVRNIDAFYEAFGVTESDELYLEPERRVRIWN
Mflv_0472|M.gilvum_PYR-GCK          EFRCNGVIRNMDAFYDAFDVDPEDALYLEPQRRVHIWN
Mvan_0184|M.vanbaalenii_PYR-1       EFRCNAVVRNMDAFYDAFEVDEDDELYLEPQRRVHIWN
MAB_4536|M.abscessus_ATCC_1997      EFRCNGVVRNIDAFYEAFGLTTEDELFLEADQRVRIWS
                                    *****.*:**:* **:**    .. *:* .: **:**.