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AISDIQEFAHLTEADVEALGHELDAIRRDVEESLGAADARYIRRTIAAQRTLELTGRILLAASKKRSAWW AGAVTLGVAKIVENMEIGHNVMHGQWDWMNDPEIHSSSWEWDMVDPAEHWKQTHNYIHHKYTNVLGMDDD VGYGLLRVTRDKKWKPFNLGNLLYNTLLMLLFEWGVGTQHLELGKVAQGRADKEEFRVKRQAALTKMGKQ VAKDYVAFPALSALSPAGSYRKTVTANLLANVIRNIWSNAVIFCGHFPDGAEKFTKQDLENETQGQWYLR QMLGSANFDAGPAMAFMSGNLCHQIEHHLFPDLPSNRLSAVSVRVRELCDKYDLPYTSGPFLVQYAKAWR TIAKLSLPDKYLTYTADNAQETRSVKMFDELEPHERRGLKSAFAAVRARRKARHKV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3548c | - | - | 100% (407) | putative fatty acid desaturase |
| M. abscessus ATCC 19977 | MAB_2148 | - | e-163 | 66.59% (410) | putative linoleoyl-CoA desaturase |
| M. abscessus ATCC 19977 | MAB_1587c | - | e-100 | 48.29% (350) | fatty acid desaturase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3258c | - | 1e-178 | 69.49% (413) | linoleoyl-CoA desaturase |
| M. gilvum PYR-GCK | Mflv_4698 | - | 1e-178 | 70.54% (404) | fatty acid desaturase |
| M. tuberculosis H37Rv | Rv3229c | - | 1e-178 | 69.49% (413) | linoleoyl-CoA desaturase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1315 | desA3 | 1e-180 | 70.46% (413) | linoleoyl-CoA desaturase, DesA3 |
| M. avium 104 | MAV_4192 | - | 1e-180 | 70.94% (413) | Fatty acid desaturase |
| M. smegmatis MC2 155 | MSMEG_1886 | - | 1e-174 | 69.16% (415) | Fatty acid desaturase |
| M. thermoresistible (build 8) | TH_0650 | desA3 | 0.0 | 73.48% (411) | POSSIBLE LINOLEOYL-CoA DESATURASE (DELTA(6)-DESATURASE) |
| M. ulcerans Agy99 | MUL_2565 | desA3 | 1e-179 | 69.73% (413) | linoleoyl-CoA desaturase, DesA3 |
| M. vanbaalenii PYR-1 | Mvan_1768 | - | 1e-179 | 71.29% (404) | fatty acid desaturase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3258c|M.bovis_AF2122/97 MAITDVDVFAHLTDADIENLAAELDAIRRDVEESRGERDARYIRRTIAAQ
Rv3229c|M.tuberculosis_H37Rv MAITDVDVFAHLTDADIENLAAELDAIRRDVEESRGERDARYIRRTIAAQ
MMAR_1315|M.marinum_M MAITDVDVFAHLTDADIENLAIELDAIRQDIEDSRGERDARYIRRTIAAQ
MUL_2565|M.ulcerans_Agy99 MVITDVDVFAHLTDADIENLAIELDAIRQDIEDSRGERDARYIRRTIAAQ
MAV_4192|M.avium_104 MAITDVDVFAHLTDADIENLAVELDAIRQDVEDSRGERDARYIRRTIAAQ
Mflv_4698|M.gilvum_PYR-GCK MAITDVPEFAHLTDADIENLGRELDAIRQDIEDSRGAQDARYIRRTIAIQ
Mvan_1768|M.vanbaalenii_PYR-1 MAITDVPQFAHLTEADVENLGRELDAIRQDIEDSRGERDARYIRRTIAIQ
MSMEG_1886|M.smegmatis_MC2_155 MAVTDVPAFAHLTEADIENLGIELDAIRQDIEDSRGERDARYIRRTIAVQ
TH_0650|M.thermoresistible__bu MAITDVPAYAHLTEVDIDALAVELDAIRRDIEDSLGERDARYIRRTIATQ
MAB_3548c|M.abscessus_ATCC_199 MAISDIQEFAHLTEADVEALGHELDAIRRDVEESLGAADARYIRRTIAAQ
*.::*: :****:.*:: *. ******:*:*:* * ********** *
Mb3258c|M.bovis_AF2122/97 RALEVSGRLLLAGSSRRLAWWTGALTLGVAKIIENMEIGHNVMHGQWDWM
Rv3229c|M.tuberculosis_H37Rv RALEVSGRLLLAGSSRRLAWWTGALTLGVAKIIENMEIGHNVMHGQWDWM
MMAR_1315|M.marinum_M RALEVSGRLMLAASSRRSAWWAGALTLGVAKIVENMEIGHNVMHGQWDWM
MUL_2565|M.ulcerans_Agy99 RALEVSGRLMLAASSRRSAWWAGALTLGVAKIVENMEIGHNVMHGQWDWM
MAV_4192|M.avium_104 RALEVTGRLLLAASSRRSAWWAGTVTLGVAKIIENMEIGHNVMHGQWDWM
Mflv_4698|M.gilvum_PYR-GCK RGLEVAGRLMLAGSAKRSYWWAGTATLGVAKIIENMEIGHNVMHGQWDWM
Mvan_1768|M.vanbaalenii_PYR-1 RGLEVTGRLLLAGSAKRRFWWAGTATLGVAKIIENMEIGHNVMHGQWDWM
MSMEG_1886|M.smegmatis_MC2_155 RSLDLAGRLMLTASKRRSAWWAGTATLGVAKIIENMEIGHNVMHGQWDWM
TH_0650|M.thermoresistible__bu RGLEVAGRLLLAASSRRSAWWAGAVTLAAAKIIENMEIGHNVMHGQWDWM
MAB_3548c|M.abscessus_ATCC_199 RTLELTGRILLAASKKRSAWWAGAVTLGVAKIVENMEIGHNVMHGQWDWM
* *:::**::*:.* :* **:*: **..***:*****************
Mb3258c|M.bovis_AF2122/97 NDPEIHSSTWEWDMSGSSKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVT
Rv3229c|M.tuberculosis_H37Rv NDPEIHSSTWEWDMSGSSKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVT
MMAR_1315|M.marinum_M NDPEIHSSSWEWDITGASKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVT
MUL_2565|M.ulcerans_Agy99 NDPEIHSSSWEWDITGASKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVT
MAV_4192|M.avium_104 NDPEIHSSTWEWDMSGSSKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVT
Mflv_4698|M.gilvum_PYR-GCK NDPEIHSSSWEWDMSGASKHWRFTHNFMHHKYTNILGMDDDVGYGVIRVT
Mvan_1768|M.vanbaalenii_PYR-1 NDPEIHSSSWEWDMSGASKHWRFTHNFMHHKYTNILGMDDDVGYGVIRVT
MSMEG_1886|M.smegmatis_MC2_155 NDPEIHSSSWEWDMSGASKHWRFTHNFMHHKYTNILGMDDDVGYGLLRVT
TH_0650|M.thermoresistible__bu NDPEIHSSTWEWDMTGASKHWRFTHNFMHHKYTNILGMDDDVGYGLLRVT
MAB_3548c|M.abscessus_ATCC_199 NDPEIHSSSWEWDMVDPAEHWKQTHNYIHHKYTNVLGMDDDVGYGLLRVT
********:****: ..::**: ***::******:**********::***
Mb3258c|M.bovis_AF2122/97 RDQRWKRYNIFNVVWNTILAIGFEWGVALQHLEIGKIFKGRADREAAKTR
Rv3229c|M.tuberculosis_H37Rv RDQRWKRYNIFNVVWNTILAIGFEWGVALQHLEIGKIFKGRADREAAKTR
MMAR_1315|M.marinum_M RDQRWKRYNIFNLVWNTLLALGFEWGVALQHLEIGKLLKGRLDRDTARTR
MUL_2565|M.ulcerans_Agy99 RDQRWKRYNIFNLVWNTLLALGFEWGVALQHLEIGKLLKGRLDRDTAETR
MAV_4192|M.avium_104 RDQRWKRFNLFNLVWNTLLALLFEWGVGLQHVEIGKILKRRMDHEEARQR
Mflv_4698|M.gilvum_PYR-GCK RDQRWTPMNLGNLFFNTLLCVAFEWGVGLQHLELGKIFKGRDDRKATMGR
Mvan_1768|M.vanbaalenii_PYR-1 RDQRWRPMNLLNLFFNTLLSVAFEWGVGLQHLELGKIFKGRDDRKATMGR
MSMEG_1886|M.smegmatis_MC2_155 RDQKWKPHNLLNLVYNTMLCIFFEWGVGLQHLEVGKIFKGRDDRNATLVR
TH_0650|M.thermoresistible__bu RDQKWKPFNLGNLLYNTLLALAFEWGVGLQHVELGKIFKRRHDPDESRVR
MAB_3548c|M.abscessus_ATCC_199 RDKKWKPFNLGNLLYNTLLMLLFEWGVGTQHLELGKVAQGRADKEEFRVK
**::* *: *:.:**:* : *****. **:*:**: : * * . :
Mb3258c|M.bovis_AF2122/97 LREFSAKAGRQVFKDYVAFPALTSLSPGATYRSTLTANVVANVIRNVWSN
Rv3229c|M.tuberculosis_H37Rv LREFSAKAGRQVFKDYVAFPALTSLSPGATYRSTLTANVVANVIRNVWSN
MMAR_1315|M.marinum_M VREFSRKAGRQVFKDYVAFPALTSVSPGATYRSTLTANVTANVLRNVWTN
MUL_2565|M.ulcerans_Agy99 VREFSRKAGRQVFKDYVAFPALTSVSPGATYRSTLTANVTANVLRNVWTN
MAV_4192|M.avium_104 IDEFLAKAGRQVVKDYVAFPALTSLSPGATFLSTLKANAMANVIRNVWAN
Mflv_4698|M.gilvum_PYR-GCK VKEFGVKAGQQVVKDYVAYPAITSLSPRATFKSTLTANAVANVIRNVWAN
Mvan_1768|M.vanbaalenii_PYR-1 VKEFGVKAGQQVVKDYVAYPAITSLSPRATFRSTLTANAVANVIRNVWAN
MSMEG_1886|M.smegmatis_MC2_155 LREFGTKAGGQVFKDYVAWPAITSLSPGATFKSTAKANAVANIIRNIWSN
TH_0650|M.thermoresistible__bu VREFLRKAGRQVFKDYVAYPALSSLSPAASYRSTLTANAMANVIRNVWSN
MAB_3548c|M.abscessus_ATCC_199 RQAALTKMGKQVAKDYVAFPALSALSPAGSYRKTVTANLLANVIRNIWSN
* * ** *****:**::::** .:: .* .** **::**:*:*
Mb3258c|M.bovis_AF2122/97 AVIFCGHFPDGAEKFTKTDMIGEPKGQWYLRQMLGSANFNAGPALRFMSG
Rv3229c|M.tuberculosis_H37Rv AVIFCGHFPDGAEKFTKTDMIGEPKGQWYLRQMLGSANFNAGPALRFMSG
MMAR_1315|M.marinum_M AVIFCGHFPDGAEKFTKTDMVGETKGQWYLRQMLGSANFEAGPALRFMSG
MUL_2565|M.ulcerans_Agy99 AVIFCGHFPDGAEKFTKADMVGETKGQWYLRQMLGSANFEAGPALRFMSG
MAV_4192|M.avium_104 AVIFCGHFPDGAEKFTKTDMIGETKGQWYLRQMLGSANFEAGPVLRFMSG
Mflv_4698|M.gilvum_PYR-GCK AVIFCGHFPDGAEKFTKTDMIGESRGQWYLRQMLGSANFEGGPLLRFMSG
Mvan_1768|M.vanbaalenii_PYR-1 AVIFCGHFPDGAEKFTKTDMVGESRGQWYLRQMLGSANFEGGPLLRFMSG
MSMEG_1886|M.smegmatis_MC2_155 AVIFCGHFPDGAEKFTKTDMIGESRGQWYLRQMLGSANFEGGWLLRFMSG
TH_0650|M.thermoresistible__bu AVIFCGHFPDGAEKFTKTDMVGESKGQWYLRQMLGSANFEGGWLLRFMSG
MAB_3548c|M.abscessus_ATCC_199 AVIFCGHFPDGAEKFTKQDLENETQGQWYLRQMLGSANFDAGPAMAFMSG
***************** *: .*.:**************:.* : ****
Mb3258c|M.bovis_AF2122/97 NLCHQIEHHLYPDLPSNRLHEISVRVREVCDRYDLPYTTGSFLVQYGKTW
Rv3229c|M.tuberculosis_H37Rv NLCHQIEHHLYPDLPSNRLHEISVRVREVCDRYDLPYTTGSFLVQYGKTW
MMAR_1315|M.marinum_M NLCHQIEHHLYPDLPSNRLAEVSVRVREICDKYDLPYTTGSFLVQYGKTW
MUL_2565|M.ulcerans_Agy99 NLCHQIEHHLYPDLPSNRLAEVSVRVREICDKYDLPYTTGSFLVQYGKTW
MAV_4192|M.avium_104 NLCHQIEHHLYPDLPSNRLHEISVRVRQVCDKYDLPYTTGSFLFQYAKTW
Mflv_4698|M.gilvum_PYR-GCK NLSQQIEHHLFPDLPSNRYYEISLRVRELCDKYDLPYTTGNFLVQYGKSW
Mvan_1768|M.vanbaalenii_PYR-1 NLSQQIEHHLFPDLPSNRYYEISLRVRELCDKYDLPYTTGNFLVQYGKSW
MSMEG_1886|M.smegmatis_MC2_155 NLCHQIEHHLYPDLPSNRLHEISIRVRALCDKYDLPYTTGSFLVQYGKTW
TH_0650|M.thermoresistible__bu NLCHQIEHHLYPDLPSNRLHEASIRVREVCDKYDLPYTTGPFLVQYAKTW
MAB_3548c|M.abscessus_ATCC_199 NLCHQIEHHLFPDLPSNRLSAVSVRVRELCDKYDLPYTSGPFLVQYAKAW
**.:******:******* *:*** :**:******:* **.**.*:*
Mb3258c|M.bovis_AF2122/97 RTLAKLSLPDKYLRDNADDAPETRSERMFAGLGPGFAGADPVTGRRRGLK
Rv3229c|M.tuberculosis_H37Rv RTLAKLSLPDKYLRDNADDAPETRSERMFAGLGPGFAGADPVTGRRRGLK
MMAR_1315|M.marinum_M RTLAKLSLPNKYLRDNADNAPETRSERMFADLEPGFAGADPRTGRRRGLK
MUL_2565|M.ulcerans_Agy99 RTLAKLSLPNKYLRDNADDAPETRSERMFADLEPGFAGADPRTGRRRGLK
MAV_4192|M.avium_104 RTLAKLSLPNKYLRDDADNAPETRSERMFAELDPDFLGTDPATGRRRGLK
Mflv_4698|M.gilvum_PYR-GCK RTIAKLSLPDRFLSDTRDDAPETRSERMFDGLE-------PTE--RSGLK
Mvan_1768|M.vanbaalenii_PYR-1 RTIAKLSLPDRFLTDTADDAPETRSERMFDGLE-------PSE--RRGLR
MSMEG_1886|M.smegmatis_MC2_155 RTIAKLSLPDKFLKDTADNAPETRSERMFAELDG-FGVTDPATGRRRGLK
TH_0650|M.thermoresistible__bu RTLAKLSLPDRFLKATADNAPETRSERMFAELGPGFAGVDPATGRRRGLK
MAB_3548c|M.abscessus_ATCC_199 RTIAKLSLPDKYLTYTADNAQETRSVKMFDELEP---------HERRGLK
**:******:::* *:* **** :** * * **:
Mb3258c|M.bovis_AF2122/97 TAIAAVRGRRRSKRMAKSVTE-PDDLAA----------------------
Rv3229c|M.tuberculosis_H37Rv TAIAAVRGRRRSKRMAKSVTE-PDDLAA----------------------
MMAR_1315|M.marinum_M SAIAAVRGRRRGKRVPEVRDSGTNDLAA----------------------
MUL_2565|M.ulcerans_Agy99 SAIAAVRGRRRGKRVPEVRDSGTNDLAA----------------------
MAV_4192|M.avium_104 SAIAAVRGWRRGKRASVARRT-GGELAA----------------------
Mflv_4698|M.gilvum_PYR-GCK SAIAAVRSRRRAKRAQKAAVKGQDLAA-----------------------
Mvan_1768|M.vanbaalenii_PYR-1 SAIAAVRKRRRAKAAEKAAVK---LAA-----------------------
MSMEG_1886|M.smegmatis_MC2_155 TAIETVRGWRRSSRAKRAA-------------------------------
TH_0650|M.thermoresistible__bu SAFAAVRNWRRDKQAAKAXXXGELYPRPGTLRRDVGVRLRRGGVPGPAGL
MAB_3548c|M.abscessus_ATCC_199 SAFAAVRARRKARHKV----------------------------------
:*: :** *:
Mb3258c|M.bovis_AF2122/97 --------------------------------------
Rv3229c|M.tuberculosis_H37Rv --------------------------------------
MMAR_1315|M.marinum_M --------------------------------------
MUL_2565|M.ulcerans_Agy99 --------------------------------------
MAV_4192|M.avium_104 --------------------------------------
Mflv_4698|M.gilvum_PYR-GCK --------------------------------------
Mvan_1768|M.vanbaalenii_PYR-1 --------------------------------------
MSMEG_1886|M.smegmatis_MC2_155 --------------------------------------
TH_0650|M.thermoresistible__bu WSGEHDRRGHRPPRSGPQRIRRPRGHAVLRRRDRAVRR
MAB_3548c|M.abscessus_ATCC_199 --------------------------------------