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LGGGSMRTVATICVVAGLLAGCSTPAAEEGPSTPPGTTVPTVVPGVMPNLAGLQWSDVKPLLRKLGRVNV TTKEVPVNDAEQKSRIVSQDPAAGAHLEPGAKIVLTFGT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_3436 | - | - | 100% (109) | hypothetical protein MAB_3436 |
M. abscessus ATCC 19977 | MAB_0033c | - | 5e-07 | 39.06% (64) | serine/threonine-protein kinase PknB |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0014c | pknB | 1e-08 | 38.54% (96) | transmembrane serine/threonine-protein kinase B PKNB |
M. gilvum PYR-GCK | Mflv_0812 | - | 1e-07 | 37.36% (91) | protein kinase |
M. tuberculosis H37Rv | Rv0014c | pknB | 2e-08 | 38.54% (96) | transmembrane serine/threonine-protein kinase B PKNB |
M. leprae Br4923 | MLBr_00016 | pknB | 1e-07 | 36.67% (90) | putative serine/threonine protein kinase |
M. marinum M | MMAR_0016 | pknB | 1e-07 | 37.50% (96) | serine/threonine-protein kinase B PknB |
M. avium 104 | MAV_0017 | - | 4e-08 | 37.50% (96) | serine/threonine protein kinase |
M. smegmatis MC2 155 | MSMEG_0028 | - | 3e-08 | 38.14% (97) | serine-threonine protein kinase |
M. thermoresistible (build 8) | TH_2631 | - | 6e-08 | 35.16% (91) | PUTATIVE serine/threonine protein kinase |
M. ulcerans Agy99 | MUL_0018 | pknB | 1e-07 | 37.50% (96) | serine/threonine-protein kinase B PknB |
M. vanbaalenii PYR-1 | Mvan_0023 | - | 3e-08 | 34.65% (101) | protein kinase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0016|M.marinum_M MTTPQHLSDRYELGDILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP MUL_0018|M.ulcerans_Agy99 MTTPQHLSDRYELGDILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP Mb0014c|M.bovis_AF2122/97 MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP Rv0014c|M.tuberculosis_H37Rv MTTPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP MLBr_00016|M.leprae_Br4923 MTTPPHLSDRYELGDILGFGGMSEVHLARDIRLHRDVAVKVLRADLARDP MAV_0017|M.avium_104 MTTPQHLSDRYELGEILGFGGMSEVHLARDVRLHRDVAVKVLRADLARDP TH_2631|M.thermoresistible__bu MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP Mflv_0812|M.gilvum_PYR-GCK MTTPQHLSDRYEVGEILGFGGMSEVHLARDLRLHRDVAIKVLRADLARDP Mvan_0023|M.vanbaalenii_PYR-1 MTTPQHLSDRYEVGEILGFGGMSEVHLARDLRLHRDVAIKVLRADLARDP MSMEG_0028|M.smegmatis_MC2_155 MTTPQHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKVLRADLARDP MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPSGPLPYIVMEYVNGVTL MUL_0018|M.ulcerans_Agy99 SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPSGPLPYIVMEYVNGFTL Mb0014c|M.bovis_AF2122/97 SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTL Rv0014c|M.tuberculosis_H37Rv SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPAGPLPYIVMEYVDGVTL MLBr_00016|M.leprae_Br4923 SFYLRFRREAQNAAALNHPSIVAVYDTGEAETSAGPLPYIVMEYVDGATL MAV_0017|M.avium_104 SFYLRFRREAQNAAALNHPSIVAVYDTGEAETPSGPLPYIVMEYVDGVTL TH_2631|M.thermoresistible__bu SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPTGPLPYIVMEYVDGVTL Mflv_0812|M.gilvum_PYR-GCK SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPTGPLPYIVMEYVDGVTL Mvan_0023|M.vanbaalenii_PYR-1 SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPTGPLPYIVMEYVDGVTL MSMEG_0028|M.smegmatis_MC2_155 SFYLRFRREAQNAAALNHPAIVAVYDTGEAETPNGPLPYIVMEYVDGVTL MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M RDIVHTDGPMAPTRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTN MUL_0018|M.ulcerans_Agy99 RDIVHTDGPMAPTRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTN Mb0014c|M.bovis_AF2122/97 RDIVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATN Rv0014c|M.tuberculosis_H37Rv RDIVHTEGPMTPKRAIEVIADACQALNFSHQNGIIHRDVKPANIMISATN MLBr_00016|M.leprae_Br4923 RDIVHTDGPMPPQQAIEIVADACQALNFSHQNGIIHRDVKPANIMISATN MAV_0017|M.avium_104 RDIVHTDGPLPPRRAIEIIADACQALNFSHQNGIIHRDVKPANIMISTTN TH_2631|M.thermoresistible__bu RDIVHTDGPMEPKRAIEVIADACQALNFSHQHGIIHRDVKPANIMISKTG Mflv_0812|M.gilvum_PYR-GCK RDIVHSDGPMPPQRAIEVIADACQALNFSHQHGIIHRDVKPANIMISKTG Mvan_0023|M.vanbaalenii_PYR-1 RDIVHNDGPMAPQRAIEVIADACQALNFSHQHGIIHRDVKPANIMISKTG MSMEG_0028|M.smegmatis_MC2_155 RDIVHTDGPIAPRRAIEIIADACQALNFSHQHGIIHRDVKPANIMISKNN MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVY MUL_0018|M.ulcerans_Agy99 AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVY Mb0014c|M.bovis_AF2122/97 AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVY Rv0014c|M.tuberculosis_H37Rv AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDSVDARSDVY MLBr_00016|M.leprae_Br4923 AVKVMDFGIARAIADS-TSVTQTAAVIGTAQYLSPEQARGDSVDARSDVY MAV_0017|M.avium_104 AVKVMDFGIARAIADSGNSVTQTAAVIGTAQYLSPEQARGDAVDARSDVY TH_2631|M.thermoresistible__bu AVKVMDFGIARAIADS-NSVTQTAAVIGTAQYLSPEQARGETVDARSDVY Mflv_0812|M.gilvum_PYR-GCK AVKVMDFGIARALADAGNPVTQTAAVIGTAQYLSPEQARGVKVDARSDVY Mvan_0023|M.vanbaalenii_PYR-1 AVKVMDFGIARALADAGNPVTQTAAVIGTAQYLSPEQARGVKVDARSDVY MSMEG_0028|M.smegmatis_MC2_155 AVKVMDFGIARALADTGNSVTQTAAVIGTAQYLSPEQARGETVDARSDVY MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M SLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSERHEGISAELDAV MUL_0018|M.ulcerans_Agy99 SLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPIPPSERHEGIFAELDAV Mb0014c|M.bovis_AF2122/97 SLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAV Rv0014c|M.tuberculosis_H37Rv SLGCVLYEVLTGEPPFTGDSPVSVAYQHVREDPIPPSARHEGLSADLDAV MLBr_00016|M.leprae_Br4923 SLGCVLYEILTGEPPFIGDSPVSVAYQHVREDPIPPSQRHEGISVDLDAV MAV_0017|M.avium_104 SLGCVLYEILTGEPPFTGDSPVAVAYQHVREDPVPPSQRHEGISADLDAV TH_2631|M.thermoresistible__bu SLGCVLYEILTGEPPFVGDSPVAVAYQHVREDPVPPSRRNPAVSPELDAV Mflv_0812|M.gilvum_PYR-GCK SLGCVLYEMLTGEPPFVGDSPVAVAYQHVREDPVPPSQRHTGISPELDAV Mvan_0023|M.vanbaalenii_PYR-1 SLGCVLYEVLTGEPPFVGDSPVAVAYQHVREDPVPPSQRHAGISPELDAV MSMEG_0028|M.smegmatis_MC2_155 SLGCVLYEILTGEPPFIGDSPVAVAYQHVREDPVPPSRRHADVTPELDAV MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M VLKALAKNPDNRYQTAAEMRADLVRVHNGESPEAPKVLTGAERRSLTASS MUL_0018|M.ulcerans_Agy99 VLKALAKNPDNRYQTAAEMRADLVRVHNGEAPEAPKVLTGAERRSLTTSS Mb0014c|M.bovis_AF2122/97 VLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA Rv0014c|M.tuberculosis_H37Rv VLKALAKNPENRYQTAAEMRADLVRVHNGEPPEAPKVLTDAERTSLLSSA MLBr_00016|M.leprae_Br4923 VLKALAKNPENRYQTAAEMRADLIRVHSGQPPEAPKVLTDADRSCLLSSG MAV_0017|M.avium_104 VLKALAKNPDNRYQTAAEMRADLVRVHNGEKPEAPKVLTDAERSSLLSSG TH_2631|M.thermoresistible__bu VLKALAKNPDNRYQTAAEMRADLVRVHSGEQPEAPKVLTDAERTSLLASG Mflv_0812|M.gilvum_PYR-GCK VLKALAKNPDNRYQTAAEMRSDLVKVHSGEIPDAPKVFTDAERTSLLAST Mvan_0023|M.vanbaalenii_PYR-1 VLKALAKNPDNRYQTAAEMRTDLVRVHSGEAPDAPKVFTDAERTSLLAAN MSMEG_0028|M.smegmatis_MC2_155 VLKALAKNPDNRYQTAAEMRADLIRVHEGQAPDAPKVLTDAERTSMLAAP MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M PSSPAAPRTDPLPRQTLDDTDRDRSTPSVGRWVAVVAVLAVLTIVVTIAI MUL_0018|M.ulcerans_Agy99 PSSPAAPRTDPLPRQTLDDTDRDRSTPSVGRWVAVVAVLAVLTIVVTIAI Mb0014c|M.bovis_AF2122/97 AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAI Rv0014c|M.tuberculosis_H37Rv AGNLSGPRTDPLPRQDLDDTDRDRSIGSVGRWVAVVAVLAVLTVVVTIAI MLBr_00016|M.leprae_Br4923 AGNFGVPRTDALSRQSLDETESD---GSIGRWVAVVAVLAVLTIAIVAAF MAV_0017|M.avium_104 AGAAGPSRTDPLPRQVLADSGEDRTVGSVGRWIVAVAALAVLTIIVVIAF TH_2631|M.thermoresistible__bu PAHDRTQPTDAVIDPVIPRYTGSDRGGSVGRWVAAVAVLAVLTVVVTVAI Mflv_0812|M.gilvum_PYR-GCK PAHLRTEPVDPVGPH-QPRYDERERGGSLGRWLIAVAVLAVLTVLVTIGI Mvan_0023|M.vanbaalenii_PYR-1 PAHHRTEPVEPAGRR-QPRYAEPERGGSLGRWLIAVAILAVLTVVVTIGI MSMEG_0028|M.smegmatis_MC2_155 PADRAGAATQDMPVPRPAGYSKQRS-TSVARWLIAVAVLAVLTVVVTVAI MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M NTFGGNTRNVQVPNVRGQASADAIAALQNRGFKTRTLLKPDSTIPPDHVI MUL_0018|M.ulcerans_Agy99 NTFGGNTRNVQVPNVRGQASADAIAALQNRGFKTRTLLKPDSTIPPDHVI Mb0014c|M.bovis_AF2122/97 NTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVI Rv0014c|M.tuberculosis_H37Rv NTFGGITRDVQVPDVRGQSSADAIATLQNRGFKIRTLQKPDSTIPPDHVI MLBr_00016|M.leprae_Br4923 NTFGGNTRDVQVPDVRGQVSADAISALQNRGFKTRTLQKPDSTIPPDHVI MAV_0017|M.avium_104 NTFGGGARDVQVPDVRGQVSADAIAALQNRGFKTRTLQKPDSAIPPDHVI TH_2631|M.thermoresistible__bu NMIGGNPRNVQVPDVSGQASADAIAALQNRGFKTRTQQQPDNSVPPDRVI Mflv_0812|M.gilvum_PYR-GCK NAFGGETREVQVPDVSGQASADAIATLQNRGFSIRTQQKPDSEVPPDHVI Mvan_0023|M.vanbaalenii_PYR-1 NMFGGGTRDVQVPDVRGQASADAIATLQNRGFSIRTQQKPDSEVPPDHVI MSMEG_0028|M.smegmatis_MC2_155 NMVGGNPRNVQVPDVAEQSADDAQAALQNRGFKTVIDRQPDNEVPPGLVI MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M GTDPAANASVSAGDQITINVSTGPEQRELPDVSSMTYAEAVKKLTAAGFG MUL_0018|M.ulcerans_Agy99 GTDPAANASVSAGDQITINVSTGPEQRELPDVSSMTYAEAVKKLTAAGFG Mb0014c|M.bovis_AF2122/97 GTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFG Rv0014c|M.tuberculosis_H37Rv GTDPAANTSVSAGDEITVNVSTGPEQREIPDVSTLTYAEAVKKLTAAGFG MLBr_00016|M.leprae_Br4923 STEPGANASVGAGDEITINVSTGPEQREVPDVSSLNYTDAVKKLTSSGFK MAV_0017|M.avium_104 GTDPGANASVSAGDEITINVSTGPEQREVPDVSSLSYSDAVTKLKAAGFS TH_2631|M.thermoresistible__bu STDPPADTSVSAGDEITVNVSTGPQQREIPDVSSLTYAEAVRRLSAAGFE Mflv_0812|M.gilvum_PYR-GCK DTDPNANTSVAAGDEITLNVSTGPEQREVPDVSGLSYADAVRRLTDAGFE Mvan_0023|M.vanbaalenii_PYR-1 DTDPGANTEVGAGDEITLNVSTGPEQREVPDVSGLSYTEAVRRLTEAGFE MSMEG_0028|M.smegmatis_MC2_155 GTDPEAGSELGAGEQVTINVSTGPEQALVPDVAGLTPTQARQKLKDAGFE MAB_3436|M.abscessus_ATCC_1997 -------------------------------------------------- MMAR_0016|M.marinum_M RFKEAKSPSTPELMGKVIGTNPPANQTSAITNVITIIVGSGPATKQIPDV MUL_0018|M.ulcerans_Agy99 RFKEAKSPSTPELMGKVIGTNPPANQTSAITNVITIIVGSGPATKQIPDV Mb0014c|M.bovis_AF2122/97 RFKQANSPSTPELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDV Rv0014c|M.tuberculosis_H37Rv RFKQANSPSTPELVGKVIGTNPPANQTSAITNVVIIIVGSGPATKDIPDV MLBr_00016|M.leprae_Br4923 SFKQANSPSTPELLGKVIGTNPSANQTSAITNVITIIVGSGPETKQIPDV MAV_0017|M.avium_104 KFKQANSPSTPELLGKVIGTNPPANQTSAITNVITLIVGSGPETKQVPDI TH_2631|M.thermoresistible__bu KFRQSESPSTPELRGKVVATNPPANQTAAITNEITVVVGTGPATREVPDI Mflv_0812|M.gilvum_PYR-GCK RFRQTTSTSLPEQKDRVLSTVPPANQTSAITNEITVVIGKGPATAVVPEC Mvan_0023|M.vanbaalenii_PYR-1 KFRQTASTSLPEQKDRVLSTVPPANQTSAITNEITIVVGKGPATAVVPEC MSMEG_0028|M.smegmatis_MC2_155 KFRESPSPSTPEQKGRVLATNPQANQTAAIINEITIVVGAGPEDAPVLSC MAB_3436|M.abscessus_ATCC_1997 ------------------------MGGGSMRTVATICVVAG-------LL .:: . : : * MMAR_0016|M.marinum_M AGQSVEEAEQNLNVYGFTKFSQASVDSPKPAGSVIATNPPAGTTVPIDSV MUL_0018|M.ulcerans_Agy99 AGQSVEEAQQNLNVYGFTKFSQASVDSPKPAGSVIATNPPAGTTVPIDSV Mb0014c|M.bovis_AF2122/97 AGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSV Rv0014c|M.tuberculosis_H37Rv AGQTVDVAQKNLNVYGFTKFSQASVDSPRPAGEVTGTNPPAGTTVPVDSV MLBr_00016|M.leprae_Br4923 TGQIVEIAQKNLNVYGFTKFSQASVDSPRPTGEVIGTNPPKDATVPVDSV MAV_0017|M.avium_104 AGQTVDIAQKNLTVYGFTKITQVQVDSPRPAGEVIGTNPPKGQTVPVDSV TH_2631|M.thermoresistible__bu TGQTVELAERNLSVYGFTKFTQSAVDSTAPAGQVVGTNPPAGTTVSLDSV Mflv_0812|M.gilvum_PYR-GCK VGQTVETCQQILSASGFTKAVPVEVDSTVSAGQVVGIEPAPGQTVPQDSV Mvan_0023|M.vanbaalenii_PYR-1 VGQTVEVCQQILSASGFTKSVPVEVDSTVAAGQVVGLEPAAGQTVPQDTV MSMEG_0028|M.smegmatis_MC2_155 AGQNAESCKAILAAGGFTNTVVVEVDNPAAAGQVVGTEPADGQSVPKDTV MAB_3436|M.abscessus_ATCC_1997 AGCSTPAAEE-------------------------GPSTPPGTTVP---- .* . .: . ... . :*. MMAR_0016|M.marinum_M IELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGSLDKGPDVDAGGSQH MUL_0018|M.ulcerans_Agy99 IELQVSKGNQFVMPDLSGMFWTDAEPRLRALGWTGSLDKGPDVDGGGSQH Mb0014c|M.bovis_AF2122/97 IELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH Rv0014c|M.tuberculosis_H37Rv IELQVSKGNQFVMPDLSGMFWVDAEPRLRALGWTGMLDKGADVDAGGSQH MLBr_00016|M.leprae_Br4923 IELQVSKGNQFVMPDLSGMFWADAEPRLRALGWTGVLDKGPDVDAGGSQH MAV_0017|M.avium_104 IELQVSKGNQFIMPDLSGMFWTDAEPRLRALGWTGILDKGPDVDAGGAQS TH_2631|M.thermoresistible__bu IELEVSKGNQFVMPDLIGMFWTDAEPRLRALGWTGVLDKGADIPNSGQRA Mflv_0812|M.gilvum_PYR-GCK IQIQVSRGNQFVMPDLTGQFWTDAEPRLRALGWTGVLDKGGDVQNSGQRT Mvan_0023|M.vanbaalenii_PYR-1 IQIQVSRGNQFVMPDLRGQFWADAEPRLRALGWTGVLDKGADVPNSGQRT MSMEG_0028|M.smegmatis_MC2_155 IQIRVSKGNQFVMPDLVGQFWSDAYPRLTALGWTGVLDKGPDVRDSGQRT MAB_3436|M.abscessus_ATCC_1997 ---TVVPG---VMPNLAGLQWSDVKPLLRKLGRVNVTTKEVPVNDAEQKS * * :**:* * * *. * * ** .. * : . : MMAR_0016|M.marinum_M NRVVYQNPPAGAGVNRDGIVTLKFGQ MUL_0018|M.ulcerans_Agy99 NRVVYQNPPAGAGVNRDGIVTLKFGQ Mb0014c|M.bovis_AF2122/97 NRVVYQNPPAGTGVNRDGIITLRFGQ Rv0014c|M.tuberculosis_H37Rv NRVVYQNPPAGTGVNRDGIITLRFGQ MLBr_00016|M.leprae_Br4923 NRVAYQNPPAGAGVNRDGIITLKFGQ MAV_0017|M.avium_104 HRVVYQNPPAGAGVNRDGIITLKFGQ TH_2631|M.thermoresistible__bu NAVVRQNPSPGAGVNYDARITLNFAS Mflv_0812|M.gilvum_PYR-GCK NAVVRQSPSAGSGVNYGATITLNFAS Mvan_0023|M.vanbaalenii_PYR-1 NAVVTQSPSPGSGVNYGSRITLNFAS MSMEG_0028|M.smegmatis_MC2_155 NAVVTQSPSAGTPVNKDAKITLSFAA MAB_3436|M.abscessus_ATCC_1997 -RIVSQDPAAGAHLEPGAKIVLTFGT :. *.*..*: :: .. :.* *.