For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSTRHGSATVVLPSDTTILITRSFDAPAALIFRALTEPELVTRWWGFEDAQWEVCEIDLRVGGTWRYVVR QPCESEPDREVAFHGEYRELDPPHRLVSTEVFEGVPEGEAVVSTTLDEVDGVTTMRVLVQHTCKEHRDGH VESGMEVGMQVSYNRIEDLLRDLG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3376 | - | - | 100% (164) | hypothetical protein MAB_3376 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0591 | - | 6e-05 | 31.00% (100) | ArsR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3233 | - | 1e-09 | 28.77% (146) | activator of Hsp90 ATPase 1 family protein |
| M. tuberculosis H37Rv | Rv0576 | - | 6e-05 | 31.00% (100) | ArsR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_2815 | - | 5e-05 | 33.33% (90) | hypothetical protein MMAR_2815 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6760 | - | 1e-05 | 26.67% (150) | hypothetical protein MSMEG_6760 |
| M. thermoresistible (build 8) | TH_4434 | - | 9e-12 | 30.00% (150) | PUTATIVE Activator of Hsp90 ATPase 1 family protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2637 | - | 8e-14 | 31.17% (154) | activator of Hsp90 ATPase 1 family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3233|M.gilvum_PYR-GCK -----------MLLQLLK--------------------------------
TH_4434|M.thermoresistible__bu -----------MILQMFKK-------------------------------
Mb0591|M.bovis_AF2122/97 MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGL
Rv0576|M.tuberculosis_H37Rv MLEVAAEPTRRRLLQLLAPGERTVTQLASQFTVTRSAISQHLGMLAEAGL
MAB_3376|M.abscessus_ATCC_1997 -----MSTRHGSATVVLPS-------------------------------
MMAR_2815|M.marinum_M --------------------------------------------------
Mvan_2637|M.vanbaalenii_PYR-1 ---------MTNALALTAP-------------------------------
MSMEG_6760|M.smegmatis_MC2_155 ----------MPVTDVKHD-------------------------------
Mflv_3233|M.gilvum_PYR-GCK --PKKLNFERTY----------PAPIDTVWRAWTDPEMLRQWWGP-----
TH_4434|M.thermoresistible__bu --TKVLNLERSY----------RAPIDTVWRAWTEPDMLRQWWGP-----
Mb0591|M.bovis_AF2122/97 VTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGD
Rv0576|M.tuberculosis_H37Rv VTARKQGRERYYRLDERGVLRLRALMESFWSDELDRLVADAAHYPPSQGD
MAB_3376|M.abscessus_ATCC_1997 --DTTILITRSF----------DAPAALIFRALTEPELVTRWWGF-----
MMAR_2815|M.marinum_M -MSPTICVDQFV----------AAPPEKVWRLLTEPDLLRRWWAEG----
Mvan_2637|M.vanbaalenii_PYR-1 VDTLAMEFTRDF----------DAPVAALYRAHADPVLVKQWLGP-----
MSMEG_6760|M.smegmatis_MC2_155 LDTLTLTITAEF----------AAPVTRIWQIYADPRQLEKVWGP-----
* .: :
Mflv_3233|M.gilvum_PYR-GCK -----EKTLVP-----------------------ECRVDLRVGGEIYIVM
TH_4434|M.thermoresistible__bu -----EKTFVP-----------------------ECDVDLRVGGALHIVM
Mb0591|M.bovis_AF2122/97 CAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTV
Rv0576|M.tuberculosis_H37Rv CAMPFEKAVVVPLDPTSTFALITQPDRLRRWMAVAARIELRTGGAYRWTV
MAB_3376|M.abscessus_ATCC_1997 -----EDAQWE-----------------------VCEIDLRVGGTWRYVV
MMAR_2815|M.marinum_M -----EVAAVVG---------------------HQFELDMPGFGKQPCKV
Mvan_2637|M.vanbaalenii_PYR-1 -----HGLEME-----------------------ITEWNFCNHGGYRYTH
MSMEG_6760|M.smegmatis_MC2_155 -----PSHPAT-----------------------VVDHDLRPGGRVTYFM
:: *
Mflv_3233|M.gilvum_PYR-GCK EAGAEMG------------------KYQGTRWPMAGTFTRVEATSGLTYD
TH_4434|M.thermoresistible__bu EAGPEMG------------------KYQGTRWPMSGTFTHIERPTRLTYD
Mb0591|M.bovis_AF2122/97 TPGHSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTPVDGGTE
Rv0576|M.tuberculosis_H37Rv TPGHSAAGTVIDVDPGKRVVFTWGWEDHGDPPPGGSTVTITLTPVDGGTE
MAB_3376|M.abscessus_ATCC_1997 RQPCESE--------------------PDREVAFHGEYRELDPPHRLVS-
MMAR_2815|M.marinum_M LEVDPPHR-------------------FVYTFTAAWTLAWTLEPEGAGTR
Mvan_2637|M.vanbaalenii_PYR-1 SN-------------------------EHGTFGFNGTFHTVRSNE--FIL
MSMEG_6760|M.smegmatis_MC2_155 TGP------------------------DGEKYAGYWEITAVDEPHSFSFL
Mflv_3233|M.gilvum_PYR-GCK ARSWTVGEEEGSTIHHTN-------DVTLSESDG----------------
TH_4434|M.thermoresistible__bu ARSWTEGEEEGTTIHHTN-------DITLTGNDG----------------
Mb0591|M.bovis_AF2122/97 VRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQHGDAGPDEWAAAPDPLDE
Rv0576|M.tuberculosis_H37Rv VRLVHDGLTAQQAARHAKGWNHFLDRLVVAGQRGDAGPDEWAAAPDPLDE
MAB_3376|M.abscessus_ATCC_1997 -TEVFEGVPEGEAVVSTT----------LDEVDG----------------
MMAR_2815|M.marinum_M VFLEHSGFDR----------------------------------------
Mvan_2637|M.vanbaalenii_PYR-1 QTFEFEGAPDMANIEYLW----------FEDLGAS---------------
MSMEG_6760|M.smegmatis_MC2_155 DGFADEDFNPNTDLPVSTN------VYTFTEHDG----------------
.
Mflv_3233|M.gilvum_PYR-GCK -----TTTVRLHVTITKIGP---------------------KAKLAAFGM
TH_4434|M.thermoresistible__bu -----STTVRMHITISRIGP---------------------KAKMAAFGM
Mb0591|M.bovis_AF2122/97 LSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRSLAIIGA
Rv0576|M.tuberculosis_H37Rv LSCAEATLAVLQHVLRGIGASDLTRQTPCTEYDVSQLADHLLRSLAIIGA
MAB_3376|M.abscessus_ATCC_1997 -----VTTMRVLVQHTCKEH---------------------RDGHVESGM
MMAR_2815|M.marinum_M ------NDKRMADAFLRMGPG--------------------WRDVVLPRL
Mvan_2637|M.vanbaalenii_PYR-1 -----RSRLRGRSICPTVEA---------------------RDALLSSGM
MSMEG_6760|M.smegmatis_MC2_155 -----GTRATYVGTYASAEA---------------------LQQVLDMGV
.
Mflv_3233|M.gilvum_PYR-GCK KWGYKAQLDKLDKLLAQ---------------------------------
TH_4434|M.thermoresistible__bu KWGYKAQLGKLEKLLSDQA-------------------------------
Mb0591|M.bovis_AF2122/97 AAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSNQVPATV
Rv0576|M.tuberculosis_H37Rv AAGAQLAPRDVDAPLETQVADAAQAVMEAWRRRGLAGTVELNSNQVPATV
MAB_3376|M.abscessus_ATCC_1997 EVGMQVSYNRIEDLLRDLG-------------------------------
MMAR_2815|M.marinum_M AAAVTATVDGAEKAAVGE--------------------------------
Mvan_2637|M.vanbaalenii_PYR-1 EGGMTEGYQKLDDLLRNLPA------------------------------
MSMEG_6760|M.smegmatis_MC2_155 IEGASSAINQIDALLTA---------------------------------
. :
Mflv_3233|M.gilvum_PYR-GCK --------------------------------------------------
TH_4434|M.thermoresistible__bu --------------------------------------------------
Mb0591|M.bovis_AF2122/97 PVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITPATRNSA
Rv0576|M.tuberculosis_H37Rv PVGILCLEFLVHAWDFAIATGSQVIASEPVSEYVLAVAGKVITPATRNSA
MAB_3376|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_2815|M.marinum_M --------------------------------------------------
Mvan_2637|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6760|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3233|M.gilvum_PYR-GCK ----------------------------------
TH_4434|M.thermoresistible__bu ----------------------------------
Mb0591|M.bovis_AF2122/97 GFAAPAAVGSFAPVLDRLIAFTGRQPTAGHVSAT
Rv0576|M.tuberculosis_H37Rv GFAAPAAVGSFAPVLDRLIAFTGRQPTAGHVSAT
MAB_3376|M.abscessus_ATCC_1997 ----------------------------------
MMAR_2815|M.marinum_M ----------------------------------
Mvan_2637|M.vanbaalenii_PYR-1 ----------------------------------
MSMEG_6760|M.smegmatis_MC2_155 ----------------------------------