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RMRETQGAQGRGRNAPPFLRTILAYIALTKPRVIELLLVTTIPAMLLADRGDVNPLLILNTLLGGVMAAA SANTLNCVADADIDKVMKRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIAFYV FVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQWPALVMFAVIFFWTPPHTWALAMRYKEDYRAA GVPMLPVIATEEKVTKLILVYTWLTVLSTLALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRP LRLFLQSNNYLAVVFCALAVDSVVGWPTLFQL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2758c | - | - | 100% (313) | protoheme IX farnesyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1486 | ctaB | 1e-131 | 74.67% (304) | protoheme IX farnesyltransferase |
| M. gilvum PYR-GCK | Mflv_3691 | - | 1e-129 | 73.27% (318) | protoheme IX farnesyltransferase |
| M. tuberculosis H37Rv | Rv1451 | ctaB | 1e-132 | 75.00% (304) | protoheme IX farnesyltransferase |
| M. leprae Br4923 | MLBr_00584 | ctaB | 1e-134 | 77.85% (289) | protoheme IX farnesyltransferase |
| M. marinum M | MMAR_2255 | ctaB | 1e-134 | 76.67% (300) | cytochrome C oxidase assembly factor CtaB |
| M. avium 104 | MAV_3326 | cyoE | 1e-141 | 81.66% (289) | protoheme IX farnesyltransferase |
| M. smegmatis MC2 155 | MSMEG_3105 | cyoE | 1e-137 | 80.62% (289) | protoheme IX farnesyltransferase |
| M. thermoresistible (build 8) | TH_0340 | ctaB | 1e-120 | 75.45% (277) | PROBABLE CYTOCHROME C OXIDASE ASSEMBLY FACTOR CTAB |
| M. ulcerans Agy99 | MUL_1845 | ctaB | 1e-134 | 76.33% (300) | protoheme IX farnesyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2721 | - | 1e-134 | 77.97% (295) | protoheme IX farnesyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1486|M.bovis_AF2122/97 MNVRGRVAPRRVTG---------------RAMSTLLAYLALTKPRVIELL
Rv1451|M.tuberculosis_H37Rv MNVRGRVAPRRVTG---------------RAMSTLLAYLALTKPRVIELL
MMAR_2255|M.marinum_M MSVHGRVAPGQVAGTARQRSEPGTGTWRSRVLGTVLAYLALTKPRVIELL
MUL_1845|M.ulcerans_Agy99 MSVHGRVAPGQVAGTARQRSEPGTGTWRSRVLGTVLAYLALTKPRVIELL
MLBr_00584|M.leprae_Br4923 --MRSTIVRSRSCALLRSRGVKYVSVRARLARSRVLAYLALTKPRVIELL
MAV_3326|M.avium_104 ----------------------------------MLAYLALTKPRVIELL
Mflv_3691|M.gilvum_PYR-GCK MRIREGHLINDSAEG------------PIGLRTRLMGYIGLTKPRVIELL
Mvan_2721|M.vanbaalenii_PYR-1 MRIREGHLVGDVAGG------------PIRFRDRVLGYIGLTKPRVIELL
TH_0340|M.thermoresistible__bu ---------------------------------------------VIELL
MSMEG_3105|M.smegmatis_MC2_155 MSIRERRLISWTPR---------------RIRTTFLAYLALTKPRVIELL
MAB_2758c|M.abscessus_ATCC_199 MRMRETQGAQGRGRN------------APPFLRTILAYIALTKPRVIELL
*****
Mb1486|M.bovis_AF2122/97 LVTAIPAMLLADRGAIHPLLMLNTLVGGMMAATGANTLNCVADADIDKVM
Rv1451|M.tuberculosis_H37Rv LVTAIPAMLLADRGAIHPLLMLNTLVGGMMAAAGANTLNCVADADIDKVM
MMAR_2255|M.marinum_M LVTAIPAMLLADRGAVHPLIIANTLIGGMMAAAGANTLNCVADADIDKVM
MUL_1845|M.ulcerans_Agy99 LVTAIPAMLLADRGAVHPLIIANTLIGGMMAAAGANTLNCVADADIDKVM
MLBr_00584|M.leprae_Br4923 LVTAIPAMLLADRGSANPLLILNTLLGGISAAAGANTFNCVADADIDKLM
MAV_3326|M.avium_104 LVTAIPAMLLAQRGTVNPLLIVNTLIGGMLAAGGANALNCVADADIDKVM
Mflv_3691|M.gilvum_PYR-GCK LVTTIPAMLLADRGTVDPLLIINTLVGGLLAAAGANTLNCVADADIDKKM
Mvan_2721|M.vanbaalenii_PYR-1 LVTTIPAMLLADRGTVDPLLILNTLVGGLLAAAGANTLNCVADADIDKKM
TH_0340|M.thermoresistible__bu LVTTIPAMLLAGRGTVDPVLIFNTLIGGMFAAGGANALNCVADADIDKVM
MSMEG_3105|M.smegmatis_MC2_155 LVTTIPAMLLADRGTVDPLLILNTLVGGMLAAAGANTLNCVADADIDKVM
MAB_2758c|M.abscessus_ATCC_199 LVTTIPAMLLADRGDVNPLLILNTLLGGVMAAASANTLNCVADADIDKVM
***:******* ** .*::: ***:**: ** .**::********** *
Mb1486|M.bovis_AF2122/97 KRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVA
Rv1451|M.tuberculosis_H37Rv KRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVA
MMAR_2255|M.marinum_M KRTARRPLARAAVPTRSALIFGLALTVISFFWLWLSANLLSGLLALATVA
MUL_1845|M.ulcerans_Agy99 NRTARRPLARAAVPTRSALIFGLALTVISFFWLWLSANLLSGLLALATVA
MLBr_00584|M.leprae_Br4923 KRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWWTTNLLSGLLALATVA
MAV_3326|M.avium_104 KRTARRPLARAAVPTRNALVFGLVLTAGSFLWLWWTTNLLSGLLALATIA
Mflv_3691|M.gilvum_PYR-GCK KRTERRALARATVPRSHALIFGLTLSVASFFWLWSTTNMLSAHLAGATIA
Mvan_2721|M.vanbaalenii_PYR-1 KRTERRALARATVPRSHALIFGLALSVLSFFWLWWTTNMLSAHLAGATIA
TH_0340|M.thermoresistible__bu KRTERRPLARDTVPRSHALVFGLALSVISFFYLWWTTNLLSAHLAGLTIA
MSMEG_3105|M.smegmatis_MC2_155 KRTARRPLARATVPTRHALIFGLVLTVTSFCWLWLSTNLLSGLLAVATIA
MAB_2758c|M.abscessus_ATCC_199 KRTARRPLAMSSVTTRNALIFGVVLGVGAFAWLWWTANLLSGLLAVATIA
:** **.** :*. ** :*:.* . :* :** ::*:*:. ** *:*
Mb1486|M.bovis_AF2122/97 FYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAI
Rv1451|M.tuberculosis_H37Rv FYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAI
MMAR_2255|M.marinum_M FYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTLAWPALAMFAI
MUL_1845|M.ulcerans_Agy99 FYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTLAWPALAMFAI
MLBr_00584|M.leprae_Br4923 FYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPALAMFAI
MAV_3326|M.avium_104 FYVFIYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFAI
Mflv_3691|M.gilvum_PYR-GCK FYVLVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLI
Mvan_2721|M.vanbaalenii_PYR-1 FYVLIYTLVLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLI
TH_0340|M.thermoresistible__bu FYVLIYTLVLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIEWPALVMFLV
MSMEG_3105|M.smegmatis_MC2_155 FYVFVYTMLLKRRTSQNVVWGGAAGCMPVMIGWSAVTGTIQWPALVMFLI
MAB_2758c|M.abscessus_ATCC_199 FYVFVYTLVLKRRTAQNVVWGGAAGCMPVMIGWSAVTNTIQWPALVMFAV
***::**: *****:********************:*.*: ****.** :
Mb1486|M.bovis_AF2122/97 IFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVA
Rv1451|M.tuberculosis_H37Rv IFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVA
MMAR_2255|M.marinum_M IFFWTPPHTWALAMRYKDDYKEAGVPMLPAVATERQVTKQILIYTWLTVL
MUL_1845|M.ulcerans_Agy99 IFFWTPPHTWALAMRYKDDYKEAGVPMLPAVATERQVTKQILIYTWLTVL
MLBr_00584|M.leprae_Br4923 IFFWTPPHTWALAMRYKDDYKVASVPMLPAVATERHVTKQILIYTWLTAL
MAV_3326|M.avium_104 IFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTKQILVYTWLTVL
Mflv_3691|M.gilvum_PYR-GCK IFFWTPPHTWALAMRYKEDYEAAGVPMLPVVATEQQVTKQILVYTWLTVL
Mvan_2721|M.vanbaalenii_PYR-1 IFFWTPPHTWALAMRYKEDYEAAGVPMLPVVATERQVTKQILIYTWLTVA
TH_0340|M.thermoresistible__bu IFFWTPPHTWALAMKYKDDYVAAGVPMLPAVATERRVTVHILVYTWLTVL
MSMEG_3105|M.smegmatis_MC2_155 IFFWTPPHTWALAMRYKDDYKAAGVPMLPAVATERQVTRQILIYTWLTVL
MAB_2758c|M.abscessus_ATCC_199 IFFWTPPHTWALAMRYKEDYRAAGVPMLPVIATEEKVTKLILVYTWLTVL
**************:**:** *.*****.:***.:** **:*****.
Mb1486|M.bovis_AF2122/97 ATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQS
Rv1451|M.tuberculosis_H37Rv ATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQS
MMAR_2255|M.marinum_M ATLALTPAAGWLYAAVAAVAGAWFLTMAHQLYAGVRAGEAVKPLRLFLQS
MUL_1845|M.ulcerans_Agy99 ATLALTPAAGWLYAAVAAVAGAWFLTMAHQLYAGVRAGEAVKPLRLFLQS
MLBr_00584|M.leprae_Br4923 STLVLALATGWLYMAVAVVAGAWFLTMAHQLYVGVCAGEPVKPLRLFLQS
MAV_3326|M.avium_104 ATLALALATGWLYAAVAVVAGVWFLAMAHQLYAGVRAGEPVKPLRLFLQS
Mflv_3691|M.gilvum_PYR-GCK ATLALALTTGWLYASVAILAGTWFLVMAHQLYAGVKRGEAVKPLRLFLQS
Mvan_2721|M.vanbaalenii_PYR-1 ATLALALATGWLYAAVAIVAGTWFLAMAHQLYAGVRRGEPVKPLRLFLQS
TH_0340|M.thermoresistible__bu STLALAPVTGWLYNSVALLAGAWFLIMAHQLYTGVRRGEPVKPLRLFLQS
MSMEG_3105|M.smegmatis_MC2_155 TTLVLALATGWLYGAVALLAGAWFLVMAHQLYSGVKRGEPVKPLRLFLQS
MAB_2758c|M.abscessus_ATCC_199 STLALALAAGVIYAVVAFLAGVWFLAMAHQLYSGVRKGQPIRPLRLFLQS
:**.*: .:. :* ** :** *** ****** ** *:.::********
Mb1486|M.bovis_AF2122/97 NNYLAVVFCALAVDSVIALPTLH--
Rv1451|M.tuberculosis_H37Rv NNYLAVVFCALAVDSVIALPTLH--
MMAR_2255|M.marinum_M NNYLALVFCALAVDSAIGLPTLLG-
MUL_1845|M.ulcerans_Agy99 NNYLALVFCALAVDSAIGLPTLLG-
MLBr_00584|M.leprae_Br4923 NNYLAVVFCALAVDSVLALPTLF--
MAV_3326|M.avium_104 NNYLAVVFCALAIDSAIGLPHLF--
Mflv_3691|M.gilvum_PYR-GCK NNYLAVVFVALAVDSALALPTLLHV
Mvan_2721|M.vanbaalenii_PYR-1 NNYLAVVFCALAVDSALALPTLFSV
TH_0340|M.thermoresistible__bu NNYLAVVFLALAIDSVLDLPTVL--
MSMEG_3105|M.smegmatis_MC2_155 NNYLAVVFCALAIDSALALPTLL--
MAB_2758c|M.abscessus_ATCC_199 NNYLAVVFCALAVDSVVGWPTLFQL
*****:** ***:**.: * :