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M. abscessus ATCC 19977 MAB_2276c (-)

annotation: putative regulatory protein
coordinates: 2323922 - 2324314
length: 130

PSIAVAMLENALAQWRGAPLTAMSESVRAQGFLRELNSHKELAQEVLLDCYLALQRYQKAAVVAHQFTLE
MPYNEKIWESHIVALRMLGRHAEAAHIFRQVQKLLYDELRVAPSKSLRSALTDTRWATA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2276c--100% (130)putative regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1298cembR6e-0928.57% (112) transcriptional regulatory protein EMBR
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv1267cembR6e-0928.57% (112) transcriptional regulatory protein EMBR
M. leprae Br4923-----
M. marinum MMMAR_4155embR8e-0928.57% (112) transcriptional regulatory protein EmbR
M. avium 104MAV_1418-3e-1032.17% (115) putative transcriptional regulator
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4018embR2e-0929.46% (112) transcriptional regulatory protein EmbR
M. vanbaalenii PYR-1Mvan_2284-6e-0526.61% (124) transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4155|M.marinum_M               MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAMLVINRNRPV
MUL_4018|M.ulcerans_Agy99           MAGSAMVDKRLEFGLLGPLEMTIDGELVPLGTPKQRAVLAMLVINRNRPV
Mb1298c|M.bovis_AF2122/97           MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPV
Rv1267c|M.tuberculosis_H37Rv        MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPV
MAV_1418|M.avium_104                -----MMAKRLEFGLLGPLEMTVDGDLVPLGTPKQRAVLAMLLMNRNNPV
Mvan_2284|M.vanbaalenii_PYR-1       --------MATELRLLGDVEVLVDGRRLDVGHARQRCVLVALLADVNQPV
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               GVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAGVDPRAMLAAAPPG
MUL_4018|M.ulcerans_Agy99           GVDSLITALWEEWPPAGARASIHSYVSNLRKLLSGAGVDPRAMLATAPPG
Mb1298c|M.bovis_AF2122/97           GVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPG
Rv1267c|M.tuberculosis_H37Rv        GVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPG
MAV_1418|M.avium_104                GIDRLITGLWDESPPSGARASLHSYVSNLRKLLSNAGVDPRTVLVAAPPG
Mvan_2284|M.vanbaalenii_PYR-1       PAEQLIDRVWAGDPPHRVRNALAGYLSRLRALFAGS---DEVTITREPGG
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               YRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALTQWRGPVL
MUL_4018|M.ulcerans_Agy99           YRLSIPDSTCDLGRFIAEKTAGVHAAAAGKFEQASQHLSRALAQWRGPVL
Mb1298c|M.bovis_AF2122/97           YRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVL
Rv1267c|M.tuberculosis_H37Rv        YRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVL
MAV_1418|M.avium_104                YRLNIPDDRCDLGRFITEKTAGVQAAASGRFEQAGAHLAAALAQWRGPVL
Mvan_2284|M.vanbaalenii_PYR-1       YMLSTDPSAVDLHRFRRLVADARSSAEP---ARAADLFDEALSLWRG-EL
MAB_2276c|M.abscessus_ATCC_199      -----------------------------MPSIAVAMLENALAQWRGAPL
                                                                     *   :  **  ***  *

MMAR_4155|M.marinum_M               DDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELEALTAE
MUL_4018|M.ulcerans_Agy99           DDLRDFQFVDAFATALVEDKILAHTAKAEAEIACGRAAAVITELEALTAE
Mb1298c|M.bovis_AF2122/97           DDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFE
Rv1267c|M.tuberculosis_H37Rv        DDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFE
MAV_1418|M.avium_104                EDLAEFRFVGTFATSLVEEKILTHIAQAEAEIACGRAFSVITELESLTRE
Mvan_2284|M.vanbaalenii_PYR-1       CTTLDTPWVNELRTALEVERLSIVSERNDAALNAGRHAELLADLVAASRA
MAB_2276c|M.abscessus_ATCC_199      TAMSESVRAQGFLRELNSHKELAQEVLLDCYLALQRYQKAAVVAHQFTLE
                                        :   .  :   *  .:        :. :   *     .     :  

MMAR_4155|M.marinum_M               HPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLGIDPGPTLRAL
MUL_4018|M.ulcerans_Agy99           HPYREPLWTQLITAYYLTDRQSDALGAYRRVKTTLAEDLSIDPGPTLRAL
Mb1298c|M.bovis_AF2122/97           HPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRAL
Rv1267c|M.tuberculosis_H37Rv        HPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRAL
MAV_1418|M.avium_104                HPYREQLWAQLMTAYYLTDRQSDALAAYRRVQKSLADDLGIDPGQNLRML
Mvan_2284|M.vanbaalenii_PYR-1       HPLDERLAGQLMLAQYGSGRQAEALDTYRRTRQRLVDELGVDPSPTLRAA
MAB_2276c|M.abscessus_ATCC_199      MPYNEKIWESHIVALRMLGRHAEAAHIFRQVQKLLYDELRVAPSKSLRSA
                                     *  * :  . : *    .*:::*   :*:.:  * ::* : *. .**  

MMAR_4155|M.marinum_M               NERILRQE----------------PLDAKMNAKSTAVGTVTVLDQRTMVS
MUL_4018|M.ulcerans_Agy99           NERILRQE----------------PLDAKMNAKSTAVGTVTVLDQRTMVS
Mb1298c|M.bovis_AF2122/97           NERILRQQ----------------PLDAKKSAKTTAAGTVTVLDQRTMAS
Rv1267c|M.tuberculosis_H37Rv        NERILRQQ----------------PLDAKKSAKTTAAGTVTVLDQRTMAS
MAV_1418|M.avium_104                NDRILRQE----------------PLDAKKNAMTTAAVTVTVLEHYTLAS
Mvan_2284|M.vanbaalenii_PYR-1       YQRILDGDSDRAPATPAVGAQGIPPADSLPRRVTSFIGRRQELAHIAAAL
MAB_2276c|M.abscessus_ATCC_199      LTDTRWATA-----------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               GQ------------------------------------QAVAYLHTIASG
MUL_4018|M.ulcerans_Agy99           GQ------------------------------------QAVAYLHTIASG
Mb1298c|M.bovis_AF2122/97           GQ------------------------------------QAVAYLHDIASG
Rv1267c|M.tuberculosis_H37Rv        GQ------------------------------------QAVAYLHDIASG
MAV_1418|M.avium_104                GR------------------------------------NAGALLHDAA-G
Mvan_2284|M.vanbaalenii_PYR-1       GQGPLLTLTGVGGAGKTRLALEAATRHKARFGDGVWWCELAALADDAAVG
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               HDYP------------------------------------IRTAATRIGR
MUL_4018|M.ulcerans_Agy99           HDYP------------------------------------IRTAATRIGR
Mb1298c|M.bovis_AF2122/97           RGYP------------------------------------LQAAATRIGR
Rv1267c|M.tuberculosis_H37Rv        RGYP------------------------------------LQAAATRIGR
MAV_1418|M.avium_104                RAFP------------------------------------LRGSTT-IGR
Mvan_2284|M.vanbaalenii_PYR-1       HAVAGALRLQQRQGLDIDATVIEYLATRELLLVIDNCEHLLDAAAQLIDR
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               LSD------------NDIVLDSANVSRHHAVIIDTGTNYIINDLRSSN--
MUL_4018|M.ulcerans_Agy99           LSD------------NDIVLDSANVSRHHAVIIDTGTNYIINDLRSSN--
Mb1298c|M.bovis_AF2122/97           LHD------------NDIVLDSANVSRHHAVIVDTGTNYVINDLRSSN--
Rv1267c|M.tuberculosis_H37Rv        LHD------------NDIVLDSANVSRHHAVIVDTGTNYVINDLRSSN--
MAV_1418|M.avium_104                LDD------------NDIVLDSPKVSRHHAVIVDTGTSYIINDLRSSN--
Mvan_2284|M.vanbaalenii_PYR-1       IVARCPGVTVLATSREALGVAGERIMPVPPLPPDEASALFADRARAGRPD
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               -----------------------GVHVQHQRIRGAVTLNDGDHIR-----
MUL_4018|M.ulcerans_Agy99           -----------------------GVHVQHQRIRGAVTLNDGDHIR-----
Mb1298c|M.bovis_AF2122/97           -----------------------GVHVQHERIRSAVTLNDGDHIR-----
Rv1267c|M.tuberculosis_H37Rv        -----------------------GVHVQHERIRSAVTLNDGDHIR-----
MAV_1418|M.avium_104                -----------------------GVHVQDQRIHSAAVLQDGDRIR-----
Mvan_2284|M.vanbaalenii_PYR-1       FDLDREPVGAVAEICRQLDGLPLAIELAAARIRVMGSLDLARRLDGLRLL
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------ICDHEFTFQLTARNPR--------------------
MUL_4018|M.ulcerans_Agy99           --------------ICDHDFTFQLTARNPR--------------------
Mb1298c|M.bovis_AF2122/97           --------------ICDHEFTFQISAGTHGGT------------------
Rv1267c|M.tuberculosis_H37Rv        --------------ICDHEFTFQISAGTHGGT------------------
MAV_1418|M.avium_104                --------------ICEHEFTFRLAEENQHAG------------------
Mvan_2284|M.vanbaalenii_PYR-1       SGGARGASPRQQSLAATIDWSYRLLSESEQQLFARLSVFAGGFDLAGAHG
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       VCAEDAAGEEDTLALLTGLVEKSIVVLRPGTGWTRYSLLETLRAYGRNLL
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       RENAIEQVYARRHAVYFTGLAERAAAGMHTVDEGAWVDRMLPDYDNLRVA
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       FDRAMADGDVDLAMRLVTSLSEFGHLRVGYEASEWAERAFAVTGPDHPLF
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       AAAVGFAARGAWNRGEDNRVRSLAALAGGRSPQRGNGRVAYPGDVLADVA
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       LYEGRPDVALAHYTAEMERARREADPIRLVWTLFYVAICYAALRTPEAGL
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       HAAQEAVQVADTTANPTARSMAGYALGLVLKKCEPEQALALFDEAAQSAA
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       SVRNFWWQGIAMMEAAATRAVHGDSARAAGEFIAVLEHWDRVGDWSQQWL
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               --------------------------------------------------
MUL_4018|M.ulcerans_Agy99           --------------------------------------------------
Mb1298c|M.bovis_AF2122/97           --------------------------------------------------
Rv1267c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_1418|M.avium_104                --------------------------------------------------
Mvan_2284|M.vanbaalenii_PYR-1       NLRYVTRLLVRLGATEDAAALHCALVKAGKPSPLTDTAVADLGRPAADGL
MAB_2276c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

MMAR_4155|M.marinum_M               -----------------
MUL_4018|M.ulcerans_Agy99           -----------------
Mb1298c|M.bovis_AF2122/97           -----------------
Rv1267c|M.tuberculosis_H37Rv        -----------------
MAV_1418|M.avium_104                -----------------
Mvan_2284|M.vanbaalenii_PYR-1       SGVDAVKRAYSALARYR
MAB_2276c|M.abscessus_ATCC_199      -----------------