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MGSDSTLAERLDEVFGAALRERRVVGAVAVVARDGQVQYRRAHGLADREGSLPMREDTLFRLASVTKPIV TVAVLRLVGDELIRLDDPVTRWLPDFTPRLPDGSTPALTIHHLLTHTAGLSYGLLEEPDSPFHALGISDG IDVVDFDLRENLRRLALAPLQFAPGSAWRYSLALDVLGAVVENATGLPLDLAVEKLVTSPLGMHESGFVA RDLTRFAVPYANGEPEPFRIADNVNVPLPQGIGVAVRFGPARVTRGDAYPSGGAGMYGTADDVLLLLEAI RAGDGFLAEELRTSMRTDHVGPQAQTRGPGWGFGYGGAVLADPAAADSPQSAGTIGWGGVYGHSWFVDAA RGLSVLLLTNTAYEGMTGPLTVEMRDAVYAAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2179 | - | - | 100% (382) | Beta-lactamase/esterase |
| M. abscessus ATCC 19977 | MAB_2833 | - | 3e-42 | 33.07% (378) | beta-lactamase |
| M. abscessus ATCC 19977 | MAB_4800 | - | 2e-23 | 34.80% (204) | putative beta-lactamase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1402c | - | 4e-34 | 33.33% (345) | hypothetical protein Mb1402c |
| M. gilvum PYR-GCK | Mflv_3749 | - | 1e-31 | 31.42% (366) | beta-lactamase |
| M. tuberculosis H37Rv | Rv1367c | - | 5e-34 | 33.33% (345) | hypothetical protein Rv1367c |
| M. leprae Br4923 | MLBr_00119 | lipE | 3e-06 | 26.09% (184) | putative hydrolase |
| M. marinum M | MMAR_2187 | - | 1e-32 | 31.59% (364) | beta-lactamase |
| M. avium 104 | MAV_3395 | - | 3e-35 | 32.73% (385) | beta-lactamase |
| M. smegmatis MC2 155 | MSMEG_3040 | - | 1e-33 | 32.51% (363) | beta-lactamase |
| M. thermoresistible (build 8) | TH_4016 | - | 5e-23 | 32.26% (341) | PUTATIVE beta-lactamase |
| M. ulcerans Agy99 | MUL_1772 | - | 1e-32 | 31.59% (364) | beta-lactamase |
| M. vanbaalenii PYR-1 | Mvan_2658 | - | 2e-33 | 32.51% (366) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1402c|M.bovis_AF2122/97 --------------------------------------------------
Rv1367c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_2187|M.marinum_M ---------------------------------------MNLDANQADIR
MUL_1772|M.ulcerans_Agy99 MGVARPRWRGPRAAWFAGARKPSDGRRLTRRPPAANLNPVNLDANQADIR
MAV_3395|M.avium_104 ---------------------------------------MTLDANSVSIR
Mflv_3749|M.gilvum_PYR-GCK ---------------------------------------MNLDRNKASIV
Mvan_2658|M.vanbaalenii_PYR-1 ---------------------------------------MNLDRNKASIA
MSMEG_3040|M.smegmatis_MC2_155 ---------------------------------------MNLDGNQTSIR
MAB_2179|M.abscessus_ATCC_1997 ----------------------------------MGSDSTLAERLDEVFG
TH_4016|M.thermoresistible__bu --------------------------------------------VIGQVD
MLBr_00119|M.leprae_Br4923 ----------MTSDGKIRVPTDLDAVTAIGDEDHSDIDSAAVERIWQATR
Mb1402c|M.bovis_AF2122/97 -------------MVWQREKLLQVNEIGYRDIDA----------GVPMQR
Rv1367c|M.tuberculosis_H37Rv -------------MVWQREKLLQVNEIGYRDIDA----------GVPMQR
MMAR_2187|M.marinum_M EVCDAGLLSGAVTVVWQHGEVLQVNEIGYRDVEA----------GLPMQR
MUL_1772|M.ulcerans_Agy99 EVCDAGLLSGAVTVVWQHGEVLQVNEIGYRDVEA----------GLPMQR
MAV_3395|M.avium_104 EVCDAGLLAGAVTMVWQRGELLQVNEIGYRDVEA----------GLPMRR
Mflv_3749|M.gilvum_PYR-GCK DAIDAGLLAGAVTLVWHAGEVRQVNELGYRDVDA----------QLPMQR
Mvan_2658|M.vanbaalenii_PYR-1 EAIDAGLLAGAVTLVWQAGEVRQVNELGYRDVEA----------RLPMQR
MSMEG_3040|M.smegmatis_MC2_155 EAIDAGLLAGAVTLVWQAGKVLQVNTLGHRDVEA----------RLPMQR
MAB_2179|M.abscessus_ATCC_1997 AALRERRVVGAVAVVARDGQVQYRRAHGLADREG----------SLPMRE
TH_4016|M.thermoresistible__bu DAVAVRRLPGAVVQIGHAGEVVFRQAFGSRKLAGEPGPTGEPTPAEPMTE
MLBr_00119|M.leprae_Br4923 HWYQAGMHPAIQLCIRQHGRVVLNRAIGHGWGNAPTDP--HDAEKIPVTT
: : .: . * . *:
Mb1402c|M.bovis_AF2122/97 DTLFRIASMTKPVT-VAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDA
Rv1367c|M.tuberculosis_H37Rv DTLFRIASMTKPVT-VAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDA
MMAR_2187|M.marinum_M DTLFRIASMTKPVT-VAAAMSMVDEGKMALRDPITRWAPELRDIRVLDDP
MUL_1772|M.ulcerans_Agy99 DTLFRIASMTKPVT-VAAAMSMVDEGKIALRDPITRWAPELRDIRVLDDP
MAV_3395|M.avium_104 DTLFRIASMTKPVT-VAAVMSLVDAGKLSLKDPVTRWAPELAGVRVLDDP
Mflv_3749|M.gilvum_PYR-GCK DTIFRIASMTKPVT-VAAAMSLVEEGRLSLTDRVATWLPELADMRVLAEP
Mvan_2658|M.vanbaalenii_PYR-1 DTIFRIASMTKPVT-VAAAMSLIDEGKLRLSDRIATWLPELADMRVLVDP
MSMEG_3040|M.smegmatis_MC2_155 DTIFRIASMTKPVT-VAAAMALAEEGKFALADPVTAWLPELSNMRVLREP
MAB_2179|M.abscessus_ATCC_1997 DTLFRLASVTKPIV-TVAVLRLVGDELIRLDDPVTRWLPDFTPRLPDGST
TH_4016|M.thermoresistible__bu DTMFDLASLTKSLATTVAVLQLAEQGRLRVDDPVQSHLPEFN--------
MLBr_00119|M.leprae_Br4923 DTPFCAYSAAKAIT-ATVVHMLVERGHFSLDDRVCEYLPTYTS-------
** * * :*.:. .... : : : * : *
Mb1402c|M.bovis_AF2122/97 AGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPD
Rv1367c|M.tuberculosis_H37Rv AGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPD
MMAR_2187|M.marinum_M HGPLDRTHPTRRPILIEDLLTHTSGLAYSFSVSGDISRAYMRLPFGHGSD
MUL_1772|M.ulcerans_Agy99 HGPLDRTHPTRRPILIEDLLTHTSGLAYSFSVSGDISRAYMRLPFGHGSD
MAV_3395|M.avium_104 HGPLDRTHPLDRAILIEDLLTHTSGLAYGFSVSGPISKAYMRLPFQHGPD
Mflv_3749|M.gilvum_PYR-GCK RGALDRTVPAQRHITIEDLMTHRSGLAYMFSVLGPLSDAYRKLPTRQDQD
Mvan_2658|M.vanbaalenii_PYR-1 RGGLDRTVPAQRHITIEDLMTHRSGLAYMFSVLGPLSDAYRKLPTRQDQD
MSMEG_3040|M.smegmatis_MC2_155 RGPLDQTVPARRPITFDDLMTHRSGMAYVFSVLGPLASAYGKISQRQDQD
MAB_2179|M.abscessus_ATCC_1997 PALTIHHLLTHTAGLSYGLLEEPDSPFHALGISDGIDVVDFDLREN----
TH_4016|M.thermoresistible__bu ----PQHDPRRARVTLRMLLTHTSGIAGDLSLDGPWGLDRPDKAEG----
MLBr_00119|M.leprae_Br4923 --------YGKHRTTIRHVLTHSAGVPFPTGPRPDVTRADDHAYAQ----
:: . . .
Mb1402c|M.bovis_AF2122/97 VWLAALATLPLVHQPGDRVTYS-HAIDVLG-VIVSRIEDAPLYQVIDERV
Rv1367c|M.tuberculosis_H37Rv VWLAALATLPLVHQPGDRVTYS-HAIDVLG-VIVSRIEDAPLYQIIDERV
MMAR_2187|M.marinum_M AWLAELAALPLVHQPGERVTYS-HAIDLLG-VIMSRIDDKPFYQVLDERI
MUL_1772|M.ulcerans_Agy99 AWLAELAALPLVHQPGERVTYS-HAIDLLG-VIMSRIDDKPFYQVLDERI
MAV_3395|M.avium_104 AWLAELAKLPLVHQPGEKVTYS-HSIDLLG-VIAARIEDKPFHQVLDERV
Mflv_3749|M.gilvum_PYR-GCK RWLTELSALPLVHQPGERLTYS-HATDVLG-IALSRIEGKPLSEVLAERI
Mvan_2658|M.vanbaalenii_PYR-1 RWLAELSALPLVHQPGERLTYS-HATDVLG-IALSRIEGKPLSEVLSERV
MSMEG_3040|M.smegmatis_MC2_155 RWLAEVAALPLAHQPGERLTYS-HSTDVLG-IALSRIEGKPLSQVLSERV
MAB_2179|M.abscessus_ATCC_1997 --LRRLALAPLQFAPGSAWRYS-LALDVLG-AVVENATGLPLDLAVEKLV
TH_4016|M.thermoresistible__bu --VRRALGAWVVHEPGRLFHYSDIGFILLG-AIVEKLTGEPLDVYVTENV
MLBr_00119|M.leprae_Br4923 ---QKLSELRPFYRPGLVHIYHALTWGPLMREIIWTATGKEIRDILAAEI
. ** * * . : : :
Mb1402c|M.bovis_AF2122/97 LGPAGMTDTGFYVSADAQ------------------------RRAATMYR
Rv1367c|M.tuberculosis_H37Rv LGPAGMTDTGFYVSADAQ------------------------RRAATMYR
MMAR_2187|M.marinum_M LGPAGMTDTGFFVSTQAQ------------------------RRAATMYR
MUL_1772|M.ulcerans_Agy99 LGPAGMTDTGFFVSTQAQ------------------------RRAATMYR
MAV_3395|M.avium_104 LGPAGMTDTGFFVSPQAR------------------------HRAATMYS
Mflv_3749|M.gilvum_PYR-GCK FEPLGMTDTGFSVGSEGR------------------------RRAATMYQ
Mvan_2658|M.vanbaalenii_PYR-1 LGPLGMSDTGFHVGPTGR------------------------RRAATMYQ
MSMEG_3040|M.smegmatis_MC2_155 FEPLGMTDTGFSIGAAGR------------------------RRAATMYK
MAB_2179|M.abscessus_ATCC_1997 TSPLGMHESGFVARDLTR------------------------FAVPYANG
TH_4016|M.thermoresistible__bu FAPLGMADTRYLPVSKACGPIRMVGNAVVEDESAEPTPCGEDRWSTSLRA
MLBr_00119|M.leprae_Br4923 LDPLGFRWTNFGVAEEDVPLVALSHATG--------------RPLPPIIA
* *: : : .
Mb1402c|M.bovis_AF2122/97 LDEQDRLRHDV-------------MGPPHVTP-PSFCNAGGGLWSTADDY
Rv1367c|M.tuberculosis_H37Rv LDEQDRLRHDV-------------MGPPHVTP-PSFCNAGGGLWSTADDY
MMAR_2187|M.marinum_M LDELDQLRHDV-------------MGPPHVRP-PSFCNAGGGLWSTADDY
MUL_1772|M.ulcerans_Agy99 LDELDQLRHDV-------------MGPPHVRP-PSFCNAGGGLWSTADDY
MAV_3395|M.avium_104 LDEHSRLQHGV-------------MGPPHVTP-PAFCNAGGGLWSSADDY
Mflv_3749|M.gilvum_PYR-GCK LDKDGTLRHDV-------------MGPAPIVD-PPFCTGGAGLFSTVDDY
Mvan_2658|M.vanbaalenii_PYR-1 LDADNTLRHDV-------------MGPAPIVD-PPFCTGGAGLWSTVDDY
MSMEG_3040|M.smegmatis_MC2_155 LTAENTLTHDV-------------MGPPPITD-PPFCAGGAGLFSTVDDY
MAB_2179|M.abscessus_ATCC_1997 EPEPFRIADNVNVPLPQGIGVAVRFGPARVTRGDAYPSGGAGMYGTADDV
TH_4016|M.thermoresistible__bu RIAPTSCDGDTPDLNPHRGRLLRGTVHDPTARRMGGVSGSAGVFSTAADV
MLBr_00119|M.leprae_Br4923 AIFRKAIGGTVH----------EVIPYTNTPPFLTTIVPSSNTVSTANEL
. ... .:. :
Mb1402c|M.bovis_AF2122/97 LRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTD----------------
Rv1367c|M.tuberculosis_H37Rv LRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTD----------------
MMAR_2187|M.marinum_M LRFVRLLLGDGTIDGVRVLSPESVRLMRTDRLSD----------------
MUL_1772|M.ulcerans_Agy99 LRFVRLLLGDGTIDGVRVLSPESVRLMRTDRLSD----------------
MAV_3395|M.avium_104 LRFVRMLLGDGTIDGVRVLSEESVRLMRTDRLTE----------------
Mflv_3749|M.gilvum_PYR-GCK LRFARMLLNGGTLDGTRVLSEDSAMSMRTDRLTA----------------
Mvan_2658|M.vanbaalenii_PYR-1 LRFAQMLLAGGELDGVRVLSEESAMSMRADRLTD----------------
MSMEG_3040|M.smegmatis_MC2_155 LVFARMLLGGGTVDGVRVLSEESVRTMRTDRLTP----------------
MAB_2179|M.abscessus_ATCC_1997 LLLLEAIRAG-----DGFLAEELRTSMRTDHVGP----------------
TH_4016|M.thermoresistible__bu GSYAQALLDRLAGRPSRFPLRRSTLQMMTSPQQPGHAPGQLDVANKAARE
MLBr_00119|M.leprae_Br4923 SRFAEIWLRGGELDGIRVLRSETLLGAVAECRRL----------------
. . :.
Mb1402c|M.bovis_AF2122/97 ---EQKRHSFLGAPFWVGRGFGLN-LSVVTDPAKSRPLFGPGGLGTFSWP
Rv1367c|M.tuberculosis_H37Rv ---EQKRHSFLGAPFWVGRGFGLN-LSVVTDPAKSRPLFGPGGLGTFSWP
MMAR_2187|M.marinum_M ---EHKRHNFLGAPFWVGRGFGLN-LSVVTDPAQSTPLFGPGGLGTFSWP
MUL_1772|M.ulcerans_Agy99 ---EHKRHNFLGAPFWVGRGFGLN-LSVVTDPVQSTPLFGPGGLGTFSWP
MAV_3395|M.avium_104 ---AQKRHNFLGAPYWVGRGFGLN-LSVVTDPARSIPLFGPGGVGTFSWP
Mflv_3749|M.gilvum_PYR-GCK ---EQKRQDFLGAPFWIGRGFGLN-LSVVTDPAKSRQLFGPGGLGTFSWP
Mvan_2658|M.vanbaalenii_PYR-1 ---EQKRHDFLGAPFWIGRGFGLN-LSVVTDPAKSRQLFGPGGVGTFSWP
MSMEG_3040|M.smegmatis_MC2_155 ---EQKQYPFLGAPFWVGRGFGLN-LSVVTDPAKSRQLFGPGGLGTFSWP
MAB_2179|M.abscessus_ATCC_1997 ---QAQTR-------GPGWGFGYG-GAVLADPAAAD---SPQSAGTIGWG
TH_4016|M.thermoresistible__bu AVLSASDDPLLAPDYPAVPGRDLRGFGWDIDTNQSRPRGSVFPVGSFGHT
MLBr_00119|M.leprae_Br4923 ------RPDFVVGLMPARWGTGFILGTNKFGP------FGRNAPAAFGHL
* . .. . .::.
Mb1402c|M.bovis_AF2122/97 GAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPK
Rv1367c|M.tuberculosis_H37Rv GAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPK
MMAR_2187|M.marinum_M GAYGTWWQADPGADLILLYLIQHCPDLSVNAAAAVAGNPGLAKLRTAQPR
MUL_1772|M.ulcerans_Agy99 GAYGTWWQADPGADLILLYLIQHCPDLSVNAAAAVAGNPGLAKLRTAQPR
MAV_3395|M.avium_104 GAYGTWWQADPTAELILIYLIQNLPDLTVDAATAVAGNTSLAKLRTAQPR
Mflv_3749|M.gilvum_PYR-GCK GAYGTWWQADPSADVILIYLIQNLPSMSVDVAAAIAGNTSLAKLQTAQPK
Mvan_2658|M.vanbaalenii_PYR-1 GAYGTWWQADPSADVILIYLIQNMPNLTADAAAAVAGNTSLAKLQSAQPK
MSMEG_3040|M.smegmatis_MC2_155 GAYGTWWQADPSADLILIYLIQNFPDLGVD-AAAIAGNTSLAKLQSAQPK
MAB_2179|M.abscessus_ATCC_1997 GVYGHSWFVDAARGLSVLLLTN----------TAYEGMTGPLTVEMRDAV
TH_4016|M.thermoresistible__bu GFTGVTLWIDPGSDTYVVVLAN---------VIHQPGGPPVAPLSGRVAT
MLBr_00119|M.leprae_Br4923 GLVNIAIWADPQRSMAAGLISS-----------GKPGQDPNAGRYGALMN
* . *. : . *
Mb1402c|M.bovis_AF2122/97 FVRRTYRALGL
Rv1367c|M.tuberculosis_H37Rv FVRRTYRALGL
MMAR_2187|M.marinum_M FVRRTYRALGL
MUL_1772|M.ulcerans_Agy99 FVRRTYRALGL
MAV_3395|M.avium_104 FVRTTYRALGL
Mflv_3749|M.gilvum_PYR-GCK FVRSTYQALEL
Mvan_2658|M.vanbaalenii_PYR-1 FVRSTYQALDL
MSMEG_3040|M.smegmatis_MC2_155 FVRRTYQALDL
MAB_2179|M.abscessus_ATCC_1997 YAAD-------
TH_4016|M.thermoresistible__bu LAARALHLYGT
MLBr_00119|M.leprae_Br4923 TITAEIPVH--