For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_1959 (-)

annotation: adenosine kinase CbhK
coordinates: 1956650 - 1957621
length: 323

VSIIVTGSIATDHLMNFPGKFSEQLLVEHLQKVSLSFLVDDLEIRRGGVAGNIGFAIGVLGGKPTLVGAV
GADFAEYRSWLEDHGVNCDAVLISETAHTARFVCTTDQDMAQIASFYPGAMSEARDISLADVVSRTGTPE
LVIIGANDPDAMFRHTEECRSLGLPFAADPSQQLARLSGEQARDLVGGAAYLFTNDYEWDLLLSKTGWTE
ADVRERVELRITTLGANGVEIVEKDGTSLKVGVVPEKGQVDPTGVGDAWRAGFLSARSAGLNLERSAQLG
SLVATLVLETVGTQEWLWERDEALVRLADAYGQEAADEIGAAL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_1959--100% (323)adenosine kinase CbhK

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2225ccbhK1e-14177.09% (323) carbohydrate kinase CbhK
M. gilvum PYR-GCKMflv_2947-1e-13872.76% (323) adenosine kinase
M. tuberculosis H37RvRv2202ccbhK1e-14177.09% (323) carbohydrate kinase CbhK
M. leprae Br4923MLBr_00873-1e-13974.61% (323) putative carbohydrate kinase
M. marinum MMMAR_3246cbhK1e-14276.47% (323) carbohydrate kinase CbhK
M. avium 104MAV_2289-1e-14277.71% (323) adenosine kinase
M. smegmatis MC2 155MSMEG_4270-1e-13673.37% (323) adenosine kinase
M. thermoresistible (build 8)TH_2399cbhK1e-12775.42% (297) Probable carbohydrate kinase CbhK
M. ulcerans Agy99MUL_3559cbhK1e-14276.16% (323) carbohydrate kinase CbhK
M. vanbaalenii PYR-1Mvan_3566-1e-13873.07% (323) adenosine kinase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2947|M.gilvum_PYR-GCK          MTIAVTGSIATDHLMRFPGKFSEQLLADHLQKVSLSFLVDDLVMHRGGVA
Mvan_3566|M.vanbaalenii_PYR-1       MTIAVTGSIATDHLMRFPGKFSEQLLADHLQKVSLSFLVDDLVMHRGGVA
MSMEG_4270|M.smegmatis_MC2_155      MTIAVTGSIATDHLMKFPGKFSEQLLADHLQKVSLSFLVDDLVIHRGGVA
Mb2225c|M.bovis_AF2122/97           MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVA
Rv2202c|M.tuberculosis_H37Rv        MTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDLVMHRGGVA
MMAR_3246|M.marinum_M               MTIAVTGSIATDHLMRFPGHFSEQLLPEHLHKVSLSFLVDDLVVHRGGVA
MUL_3559|M.ulcerans_Agy99           MTIAVTGSIATDHLMRFPGHFSEQLLPEHLHKVSLSFLVDDLVVHRGGVA
MAV_2289|M.avium_104                MTIAVTGSIATDNLMRFPGRFSEHLLAEHLQKVSLSFLVDDLVIHRGGVA
MLBr_00873|M.leprae_Br4923          MTIAVTGSIATDHLMRFPGRFSEQLLVDNLHKVSLSFLVDDLVIHRGGVA
MAB_1959|M.abscessus_ATCC_1997      MSIIVTGSIATDHLMNFPGKFSEQLLVEHLQKVSLSFLVDDLEIRRGGVA
TH_2399|M.thermoresistible__bu      VTIAVTGSIATDHLMRFPGKFSEQLLADHLQKVSLSFLVDDLVVHRGGVA
                                    ::* ********:**.***:***:** ::*:*********** ::*****

Mflv_2947|M.gilvum_PYR-GCK          GNMAFAMGVLGGNPTLVGAVGEDFDDYRNWLSAHGVNCDGVLVSQNAYTA
Mvan_3566|M.vanbaalenii_PYR-1       GNMAFAMGVLGGSPTLVGAVGEDFDEYRQWLTRHGVNCDTVLVSRSAYTA
MSMEG_4270|M.smegmatis_MC2_155      GNMAYAIGVLGGDVALVGAVGKDFDDYRGWLTTHGVNCDSVLVSESAYTA
Mb2225c|M.bovis_AF2122/97           GNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTA
Rv2202c|M.tuberculosis_H37Rv        GNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVLISETAHTA
MMAR_3246|M.marinum_M               GNMAFAIGVLGGDVALVGAAGADFADYRDWLKAHGVNCDHVLISQTAHTA
MUL_3559|M.ulcerans_Agy99           GNMAFAIGVLGGDVALVGAAGADFADYRDWLKAHGVNCDHVLISQTAHTA
MAV_2289|M.avium_104                GNIAFAIGVLGGDVALVGAAGDDFGEYRDWLQRHGVNCDHVLISQTAHTA
MLBr_00873|M.leprae_Br4923          GNMAYAIGVLGGDVALIGAVGDDFADYRDWLQNHGVNCDSVLISKTAHTA
MAB_1959|M.abscessus_ATCC_1997      GNIGFAIGVLGGKPTLVGAVGADFAEYRSWLEDHGVNCDAVLISETAHTA
TH_2399|M.thermoresistible__bu      GNMAYAIGRLGGSVALVGAAGPDFAEYRQWLESVNVDCGCVLLSETAYTA
                                    **:.:*:* ***. :*:**.* ** :** **   .*:*. **:*..*:**

Mflv_2947|M.gilvum_PYR-GCK          RFVCTTDEDMAQIASFYPGAMSEARNIKLADIVTRTGTPDLVIIGANDPE
Mvan_3566|M.vanbaalenii_PYR-1       RFVCTTDEDMAQIASFYPGAMSEARNIKLADIVKQTGTPDLVIIGANDPE
MSMEG_4270|M.smegmatis_MC2_155      RFVCTTDQDMAQIASFYPGAMSEARNISLAEVVATHGKPDLVIVGANDPD
Mb2225c|M.bovis_AF2122/97           RFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPE
Rv2202c|M.tuberculosis_H37Rv        RFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELVIIGANDPE
MMAR_3246|M.marinum_M               RFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAVGTPELVIVGANDPE
MUL_3559|M.ulcerans_Agy99           RFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAVGTPELVIVAANDPE
MAV_2289|M.avium_104                RFVCTTDQDMAQIASFYPGAMSEARNIKLADLVSSLGKPELVIIGANDPE
MLBr_00873|M.leprae_Br4923          RFVCTTDLDMAQIGSFYTGAMSEARNIKLVDAIATIGTPELVIIGANDPA
MAB_1959|M.abscessus_ATCC_1997      RFVCTTDQDMAQIASFYPGAMSEARDISLADVVSRTGTPELVIIGANDPD
TH_2399|M.thermoresistible__bu      RFVCTSDEDMAQIASFYPGAMSEARNISLADVVARIGTPELVIIGANDPE
                                    **.**:* *****.***.*******:*.*.: :   *.*:***:.**** 

Mflv_2947|M.gilvum_PYR-GCK          AMFLYTEECRALGLPFAADPSQQLARLSGDEIRKLIDGATYLFTNDYEWD
Mvan_3566|M.vanbaalenii_PYR-1       AMFLYTEECRTLGLAFAADPSQQLARLSGEEIRRLIDGAAYLFTNDYEWD
MSMEG_4270|M.smegmatis_MC2_155      AMFGHTEECRKLGLAFAADPSQQLARLSGEEIRRLIDGATYLFTNDYEWD
Mb2225c|M.bovis_AF2122/97           AMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWD
Rv2202c|M.tuberculosis_H37Rv        AMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYLFTNDYEWD
MMAR_3246|M.marinum_M               AMFLHTEECRQLGLAFAADPSQQLARLSGDEIKRLINGATYLFTNDYEWD
MUL_3559|M.ulcerans_Agy99           AMFLHTEECRQLGLAFAADPSQQLARLSGDEIKRLINGATYLFTNDYEWD
MAV_2289|M.avium_104                AMVVHTEECRKLGLPFAADPSQQLPRLSGEEIDKLVDGAAYLFTNDYEWE
MLBr_00873|M.leprae_Br4923          AMLGYTQECRKLGLAFAADPSQQLARLSGEEIRNLIDGATYLFTNDYEWD
MAB_1959|M.abscessus_ATCC_1997      AMFRHTEECRSLGLPFAADPSQQLARLSGEQARDLVGGAAYLFTNDYEWD
TH_2399|M.thermoresistible__bu      AMFRHTEECRELGLAFAADPSQQLARLSGEEIRRLINGATYLFTNDYEWD
                                    **. :*:*** ***.*********.****::   *:.**:*********:

Mflv_2947|M.gilvum_PYR-GCK          LLLQKSGWSEAEVMNQIQLRVTTLGEKGVDLVGRDGTFVHVDVVPEIHKE
Mvan_3566|M.vanbaalenii_PYR-1       LLLQKSGWSEAEVMSQIQLRVTTLGEKGVDLVGRDGTFVHVDVVPETHKE
MSMEG_4270|M.smegmatis_MC2_155      LLLQKSGWSEAEVMGQIELRVTTLGEKGVDLVGRDGTFVHVDVVPETHKE
Mb2225c|M.bovis_AF2122/97           LLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQT
Rv2202c|M.tuberculosis_H37Rv        LLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVGVVPETSQT
MMAR_3246|M.marinum_M               LLLSKTGWSEADVMAQIGLRVTTLGPKGVDLVEPDGTSIHVGVVPETSQT
MUL_3559|M.ulcerans_Agy99           LLLSKTGWSEADVMAQIGLRVTTLGPKGVDLVEPDGTSIHVGVVPETSQT
MAV_2289|M.avium_104                LLLSKTGWSEADVQQKVGLRVTTLGAKGVDIVERDGTTTRVGVVPETSQT
MLBr_00873|M.leprae_Br4923          LLLSKTGWSEADVMAQIQLRVTTLGAKGVDLVEPDGTRVHVSVVPEAGQV
MAB_1959|M.abscessus_ATCC_1997      LLLSKTGWTEADVRERVELRITTLGANGVEIVEKDGTSLKVGVVPEKGQV
TH_2399|M.thermoresistible__bu      LLLTKTGWSEAQVMSQIGLRVTTLGPKGVDLVSSDGTFVHVGVVPEKERV
                                    *** *:**:**:*  :: **:**** :**::*  ***  :*.****  : 

Mflv_2947|M.gilvum_PYR-GCK          DPTGIGDAFRAGFLTGRDAGLSLERSAQLASLVATLVLEAPGPQE-----
Mvan_3566|M.vanbaalenii_PYR-1       DPTGIGDAFRAGFLTGRDAGLSLERSAQLASMVATLVLEAPGPQE-----
MSMEG_4270|M.smegmatis_MC2_155      DPTGIGDAFRAGFLTGRSAGLSLERSAQLASMVATLVLEAPGPQE-----
Mb2225c|M.bovis_AF2122/97           DPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQE-----
Rv2202c|M.tuberculosis_H37Rv        DPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTGTQE-----
MMAR_3246|M.marinum_M               DPTGVGDAFRAGFLTGRSAGLNLERAAQLGSLVAVLVLESTGTQE-----
MUL_3559|M.ulcerans_Agy99           DPTGVGDAFRAGFLTGRSAGLNLERAAQLGSLVAVLVLESTGTQE-----
MAV_2289|M.avium_104                DPTGVGDAFRAGFLTGRSAGLNLERSAQLGSLVAVLVLESTGTQE-----
MLBr_00873|M.leprae_Br4923          DPTGVGDAFRAGFLTGRSAGLSLERSAQLGSLVAVLVLESTGTQQ-----
MAB_1959|M.abscessus_ATCC_1997      DPTGVGDAWRAGFLSARSAGLNLERSAQLGSLVATLVLETVGTQE-----
TH_2399|M.thermoresistible__bu      DPTGIGDAFRAGFLTGRSAGLSLERSAQLASLVAVLVLEAPGPRXXLRPV
                                    ****:***:*****:.*.***.***:***.*:**.****: *.:      

Mflv_2947|M.gilvum_PYR-GCK          -----------------------WHWDKD-------AAVRRLSEAYGADA
Mvan_3566|M.vanbaalenii_PYR-1       -----------------------WTWNKD-------SAVQRLTDAYGADA
MSMEG_4270|M.smegmatis_MC2_155      -----------------------WTWDRA-------DAVRRLSEAYGAEA
Mb2225c|M.bovis_AF2122/97           -----------------------WQWDYE-------AAASRLAGAYGEHA
Rv2202c|M.tuberculosis_H37Rv        -----------------------WQWDYE-------AAASRLAGAYGEHA
MMAR_3246|M.marinum_M               -----------------------WQWDRQ-------VATARLAEAYGDDA
MUL_3559|M.ulcerans_Agy99           -----------------------WQWDRQ-------VATARLAEAYGDDA
MAV_2289|M.avium_104                -----------------------WSWDHE-------VAKSRLAGAYGEDA
MLBr_00873|M.leprae_Br4923          -----------------------WGWDRD-------VAVARLAGAYGEEA
MAB_1959|M.abscessus_ATCC_1997      -----------------------WLWERD-------EALVRLADAYGQEA
TH_2399|M.thermoresistible__bu      VPVAVVMCLPARRSDPVVPYRTTGRVDRNPVSRCATRSPGRHTAGRGRSG
                                                              :          :  * : . *  .

Mflv_2947|M.gilvum_PYR-GCK          GNEIAEAL-------
Mvan_3566|M.vanbaalenii_PYR-1       AADIAAAI-------
MSMEG_4270|M.smegmatis_MC2_155      GTEIEQALSA-----
Mb2225c|M.bovis_AF2122/97           AAEIVAVLA------
Rv2202c|M.tuberculosis_H37Rv        AAEIVAVLA------
MMAR_3246|M.marinum_M               ANEITAVLA------
MUL_3559|M.ulcerans_Agy99           ANEITAVLA------
MAV_2289|M.avium_104                AAEIAAVLA------
MLBr_00873|M.leprae_Br4923          AAEITVVLS------
MAB_1959|M.abscessus_ATCC_1997      ADEIGAAL-------
TH_2399|M.thermoresistible__bu      AGPSPPSLRLRWRPR
                                    .      :