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AAASRDNVLIVHWHDLGRYLGVYGHPDVSSPHLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQSNG LIGLAHHGWEYRAGVRTLPHILSGSGWHTALFGMQHESAYPATLGFDEYDVSNSYCEYVVEHATRWLRNS PQSPFLLTAGFFETHRPFPRERYAPSDASSVDVPDYLPDTPEVRDDLAEFYGSITVADAKVGELLEVLTE TGLDQNTWVIFMTDHGPALPRAKSTLYDAGTGIALIVRPPRGRTTEPLRYEELFSGVDLLPTLLELLGVE IPEEVQGVSHAGNIQKQSGELEEVRSEVFTTKTYHDSFDPIRAIRTKNYSYIENYAPRPVLDLPWDIADS PPGRAVATHITGPRAHRELYDLRTDPEEAHNLLGLDADEASEAVANDLALRLNDWREKTLDVIPSDFAGT RISERYTETFLRIHGRPGANRSAIADERGIEQ*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_1547c | - | - | 100% (453) | sulfatase |
M. abscessus ATCC 19977 | MAB_4307 | - | 1e-07 | 27.54% (167) | arylsulfatase AtsA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0304c | - | 0.0 | 69.80% (457) | sulfatase |
M. gilvum PYR-GCK | Mflv_5039 | - | 6e-06 | 30.84% (107) | sulfatase |
M. tuberculosis H37Rv | Rv0296c | - | 0.0 | 69.80% (457) | sulfatase |
M. leprae Br4923 | - | - | - | - | - |
M. marinum M | MMAR_0554 | - | 1e-179 | 66.45% (453) | sulfatase |
M. avium 104 | MAV_4858 | - | 0.0 | 69.58% (457) | sulfatase family protein |
M. smegmatis MC2 155 | MSMEG_1228 | - | 2e-14 | 25.89% (336) | sulfatase |
M. thermoresistible (build 8) | TH_0315 | - | 4e-07 | 29.91% (107) | arylsulfatase |
M. ulcerans Agy99 | MUL_1217 | - | 1e-176 | 65.78% (450) | sulfatase |
M. vanbaalenii PYR-1 | Mvan_4274 | - | 1e-06 | 22.95% (353) | sulfatase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0554|M.marinum_M ------------------MTGAGSGSNDG--RENVLIVHWHDLGRYLGAY MUL_1217|M.ulcerans_Agy99 ----------------------------------MLIVHWHDLGRYLGAY MAV_4858|M.avium_104 --------------MTQLTPGDAGDRNDAGRKDNVLIVHWHDLGRYLGAY Mb0304c|M.bovis_AF2122/97 ----------------------MTSERATGQRENLLIVHWHDLGRYLGVY Rv0296c|M.tuberculosis_H37Rv ----------------------MTSERATGQRENLLIVHWHDLGRYLGVY MAB_1547c|M.abscessus_ATCC_199 --------------------------MAAASRDNVLIVHWHDLGRYLGVY Mflv_5039|M.gilvum_PYR-GCK MTTEFNGKIALDIRDSEPDWGPFAAPTAQPEAPNVLYLVWDDIGIATWDC TH_0315|M.thermoresistible__bu -MADFGGKIELDIRDSEPDWGPFAAPTAPEGAPNILYVVWDDVGIGTWDC MSMEG_1228|M.smegmatis_MC2_155 ----------------------------MPEKPNIVYFHVDNLGMGELGC Mvan_4274|M.vanbaalenii_PYR-1 --------------------------MTTERPDIVVVMTDEERATPPYEP :: . .: . MMAR_0554|M.marinum_M GHR----DVDSPRLDRLAGEAILFTRAHATAPLCSPSRGSLFTGRYPQSN MUL_1217|M.ulcerans_Agy99 GHR----DVDSPRLDRLAGEAILFTRAHATAPLCSPSRGSLFTGRYPQSN MAV_4858|M.avium_104 GHR----DVSSPRLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQTN Mb0304c|M.bovis_AF2122/97 HHP----DVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSN Rv0296c|M.tuberculosis_H37Rv HHP----DVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSN MAB_1547c|M.abscessus_ATCC_199 GHP----DVSSPHLDRLAAEGILFTRAHATAPLCSPSRGSLFTGRYPQSN Mflv_5039|M.gilvum_PYR-GCK FGG----LVDMPAMSRIAERGVRLSQFHTTA-LCSPTRASLLTGRNATTV TH_0315|M.thermoresistible__bu FGG----LVEMPTMSRIAEQGVRLSQFHTTA-LCSPTRAALLTGRNPTTV MSMEG_1228|M.smegmatis_MC2_155 YGGGILRGADTVRMDAFAAESLKLTHFVVEP-QCTPTRSALMTGRYPIRS Mvan_4274|M.vanbaalenii_PYR-1 DTVRAWRSRTLGGRRWFDENGVSFLRHYTGSLACVPSRPTIFTGQYPDLH : ..: : : . . * *:* :::**: . MMAR_0554|M.marinum_M GLVGLAHHGWEYRSG---------VRTLPQLLGEHGWHSALFGMQHETSQ MUL_1217|M.ulcerans_Agy99 GLVGLAHHGWEYRSG---------VRTLPQLLGEHGWHSALFGMQHETSQ MAV_4858|M.avium_104 GLIGLAHHGWEYRSG---------IRTLPQILSEAGWYSALFGMQHETSY Mb0304c|M.bovis_AF2122/97 GLVGLAHHGWEYRTG---------VQTLPQLLSESGWYSALFGMQHETSY Rv0296c|M.tuberculosis_H37Rv GLVGLAHHGWEYRTG---------VQTLPQLLSESGWYSALFGMQHETSY MAB_1547c|M.abscessus_ATCC_199 GLIGLAHHGWEYRAG---------VRTLPHILSGSGWHTALFGMQHESAY Mflv_5039|M.gilvum_PYR-GCK GMATIEEFTDGFPNCNGRIPF--DTALLSEVLSENGYNTYCIGKWHLTPL TH_0315|M.thermoresistible__bu GMATIEEFTDGFPNCSGRIPV--DTGLISEVLAEHGWNTYCVGKWHLTPL MSMEG_1228|M.smegmatis_MC2_155 GNHTIALGGNGGGIVS-------WERTMGDILSEAGYATACFGKWHIGAE Mvan_4274|M.vanbaalenii_PYR-1 GVTQTDGIGKAHDDSRLRWLRRGEVPTLGNWLRAAGYDTHYDGKWHISHA * : . * *: : * * MMAR_0554|M.marinum_M ----------------PSRLGFDELD------------------------ MUL_1217|M.ulcerans_Agy99 ----------------PSRLGFDELD------------------------ MAV_4858|M.avium_104 ----------------PKRLGFDEFD------------------------ Mb0304c|M.bovis_AF2122/97 ----------------PKRLGFDEFD------------------------ Rv0296c|M.tuberculosis_H37Rv ----------------PKRLGFDEFD------------------------ MAB_1547c|M.abscessus_ATCC_199 ----------------PATLGFDEYD------------------------ Mflv_5039|M.gilvum_PYR-GCK EESNLAA----TKRHWPLSRGFERFYGFMGGETDQWYPDLMYDNHPVAPP TH_0315|M.thermoresistible__bu EESNMAA----TKRHWPVSRGFERFYGFLGGETDQWYPDLVHDNHPVAPP MSMEG_1228|M.smegmatis_MC2_155 DG------------RWPTDHGFDEWYGPARTYDECLWPD---------DP Mvan_4274|M.vanbaalenii_PYR-1 DLIDPGTGRSLDTNDDDGVVDPAAVHRYLEADPLSPYGFSGWVGPEPHGA . MMAR_0554|M.marinum_M ----VSNSYCDYVVDKVQNWLHE------GVAALAGQPFLLTAGFFETHR MUL_1217|M.ulcerans_Agy99 ----VSSSYCDYVVDKVQNWLHE------GVAALAGQPFLLTAGFFETHR MAV_4858|M.avium_104 ----VSNSYCDYVAQRADEWLRQ------SAEGVVGQPFLLTAGFFETHR Mb0304c|M.bovis_AF2122/97 ----VSNSYCEYVVAKAQDWLHN------RVPALDGQRFLLTAGFFETHR Rv0296c|M.tuberculosis_H37Rv ----VSNSYCEYVVAKAQDWLHN------RVPALDGQRFLLTAGFFETHR MAB_1547c|M.abscessus_ATCC_199 ----VSNSYCEYVVEHATRWLRN------SPQ----SPFLLTAGFFETHR Mflv_5039|M.gilvum_PYR-GCK ATPEEGYHLSKDLADKTIEFIRD------SKVIAPDKPWFSYVCPGAGHA TH_0315|M.thermoresistible__bu ATPEDGYHLSKDLADKTIEFIRD------AKVIAPDKPWFTYLCPGAGHA MSMEG_1228|M.smegmatis_MC2_155 WYDGERDGYSYMYEGTKADGVHA------TDQQLTVKLKGEMDGEYDRRA Mvan_4274|M.vanbaalenii_PYR-1 KLSNAGIRRDPLIADRVVAWLKDRYARRRAGDPDAMRPFLLVASFVNPHD :: : MMAR_0554|M.marinum_M PYPH----------------ERYEPADSSSVDLPDYLPDTPEVR------ MUL_1217|M.ulcerans_Agy99 PYPH----------------ERYEPADSSTVDLPDYLPDTPEVR------ MAV_4858|M.avium_104 PYPE----------------DRYPPADSAEVQPPDYLPDTPEVR------ Mb0304c|M.bovis_AF2122/97 PYPH----------------ERYRPADSAAVELPDYLPDTPEVR------ Rv0296c|M.tuberculosis_H37Rv PYPH----------------ERYRPADSAAVELPDYLPDTPEVR------ MAB_1547c|M.abscessus_ATCC_199 PFPR----------------ERYAPSDASSVDVPDYLPDTPEVR------ Mflv_5039|M.gilvum_PYR-GCK PHHVFKEWADRYAGRFDMGYEAYREIVLENQKRLGLVPPDTELSAVNPYL TH_0315|M.thermoresistible__bu PHHAPRDWADRYAGRFDMGYERYREVVLENQKKLGIVPPDTELPPINPYQ MSMEG_1228|M.smegmatis_MC2_155 KAFMKR------------SVEADKPFFLYHNHSLMHFPMEVREEFKGK-- Mvan_4274|M.vanbaalenii_PYR-1 IVLFPAWARRNPLPASPLDPPPVPAAPTADEDLSTKPAAQIAFREAYYSG . . MMAR_0554|M.marinum_M -------------------------------QDLADFYGAITTADAAVGR MUL_1217|M.ulcerans_Agy99 -------------------------------QDLADFYAAITTADAAVGR MAV_4858|M.avium_104 -------------------------------GDLAAFYGAISTADAAVGR Mb0304c|M.bovis_AF2122/97 -------------------------------QDVAEFYGSIATADEAVGR Rv0296c|M.tuberculosis_H37Rv -------------------------------QDVAEFYGSIATADEAVGR MAB_1547c|M.abscessus_ATCC_199 -------------------------------DDLAEFYGSITVADAKVGE Mflv_5039|M.gilvum_PYR-GCK DVKGPDGQDWPAQDTVRPWDSLSEDEKRLFARMAEVFAGFLSYTDAQIGR TH_0315|M.thermoresistible__bu DVKGPHGEPWPLQDTVRPWDSLSDAEKRLFCRMAEVFAGFLSYTDHQIGR MSMEG_1228|M.smegmatis_MC2_155 -------------------------------STNGQWGDSLLMLDYDFGS Mvan_4274|M.vanbaalenii_PYR-1 ---------------YGPAWSIERTYRRNAQRYRDLYYRLHAEVDTPIDR : * .. MMAR_0554|M.marinum_M ILDTLEQTGL---DASTWVVFLTDHGP----------------------- MUL_1217|M.ulcerans_Agy99 ILDTLEQTGL---DGSTWVVFLTDHGP----------------------- MAV_4858|M.avium_104 LLDTLADTGL---DASTWVVFFTDHGP----------------------- Mb0304c|M.bovis_AF2122/97 LLDTLADTGL---DASTWVVFVTDHGP----------------------- Rv0296c|M.tuberculosis_H37Rv LLDTLADTGL---DASTWVVFVTDHGP----------------------- MAB_1547c|M.abscessus_ATCC_199 LLEVLTETGL---DQNTWVIFMTDHGP----------------------- Mflv_5039|M.gilvum_PYR-GCK VLDYLEESGQ---LDNTVIVVISDNGASGEGGPNGSVNEVKFFNGYIDSA TH_0315|M.thermoresistible__bu VLDYLEESDQ---LDNTLIVVLSDNGASGEGGPDGSVNEVKFFNGYVDTV MSMEG_1228|M.smegmatis_MC2_155 ILDYLAELGI---EDNTIVIMAGDNGAEDHLAGRGTAG------------ Mvan_4274|M.vanbaalenii_PYR-1 VRRAVTEGGSGDGPDDTVLVRTADHGDLLG-------------------- : : : . .* :: *:* MMAR_0554|M.marinum_M -----------------AFPR-------------AKSTLYDAGTGIAMIV MUL_1217|M.ulcerans_Agy99 -----------------AFPR-------------AKSTLYDAGTGIAMIV MAV_4858|M.avium_104 -----------------AFPR-------------AKSTLYDAGTGIGMIV Mb0304c|M.bovis_AF2122/97 -----------------AFPR-------------AKSTLYDAGTGIALII Rv0296c|M.tuberculosis_H37Rv -----------------AFPR-------------AKSTLYDAGTGIALII MAB_1547c|M.abscessus_ATCC_199 -----------------ALPR-------------AKSTLYDAGTGIALIV Mflv_5039|M.gilvum_PYR-GCK EESLKVFDELGGPQTYNHYPIGWAMAFNTPYKLFKRYASHEGGIADTAII TH_0315|M.thermoresistible__bu EESMRFYDQLGGPQTYNHYPTGWAMAFNTPYKLFKRYASHEGGIADPAII MSMEG_1228|M.smegmatis_MC2_155 ------------FFDG------------------SYFSSAEGGIRTPCLI Mvan_4274|M.vanbaalenii_PYR-1 -----------------AHGG----------LHQKWFNLYDEATRVPFVI : . :: MMAR_0554|M.marinum_M RPPKRLAVPPRVYDELFSGVDLLPTLLSLLGIDIPADVEGLS-------- MUL_1217|M.ulcerans_Agy99 RPPKRLAVPPRVYDELFSGVDLLPTLLSLLGIDIPADVEGLS-------- MAV_4858|M.avium_104 RPPTGRGLPPRVYDELFSAVDLVPTLLGLLGISVPPDVDGVS-------- Mb0304c|M.bovis_AF2122/97 RPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVS-------- Rv0296c|M.tuberculosis_H37Rv RPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVS-------- MAB_1547c|M.abscessus_ATCC_199 RPPRGRTTEPLRYEELFSGVDLLPTLLELLGVEIPEEVQGVS-------- Mflv_5039|M.gilvum_PYR-GCK SWPKGIAAHGEIRDNYVNVADITPTVYDLLDITPPATVRGVAQKPLDGVS TH_0315|M.thermoresistible__bu SWPNGITARDAVCDRYINVVDVTPTVYELIGLTPPDTVRGVRQRPLEGVS MSMEG_1228|M.smegmatis_MC2_155 RWPG--KVVPRESNEMVHVTDMFPTLLRWVGCDIPDDRIIDG-------- Mvan_4274|M.vanbaalenii_PYR-1 ARVGARPTTARTVTAPTSHVDLVPTLLSAAGVDVDAAATVLAESFSEVHP .*: **: MMAR_0554|M.marinum_M HAHALISPEADADGR----------PVREHVYAMKTYHDSFDP------- MUL_1217|M.ulcerans_Agy99 HAHALISPEADADGR----------PVREHVYAMKTYHDSFDP------- MAV_4858|M.avium_104 HASALLRPDPDAA------------PVREHVYTMKTYHDSFDP------- Mb0304c|M.bovis_AF2122/97 HAPALLAPDTENA------------AVRDHVYTAKTYHDSFDP------- Rv0296c|M.tuberculosis_H37Rv HAPALLAPDTENA------------AVRDHVYTAKTYHDSFDP------- MAB_1547c|M.abscessus_ATCC_199 HAGNIQKQSGELE------------EVRSEVFTTKTYHDSFDP------- Mflv_5039|M.gilvum_PYR-GCK FKVALENPNAPTGKETQFYTMLGTRGIWHRGWFANTVHAASPAGWSHFDD TH_0315|M.thermoresistible__bu FRAALADPDADTGKRTQFYSMLGTRGIWSDGWFANTVHAASPAGWSNFDA MSMEG_1228|M.smegmatis_MC2_155 --------------------------IDQREFFSGAEESNRDG------- Mvan_4274|M.vanbaalenii_PYR-1 LPGSDLMPVVDGAP-----------ADDHRCVYLMTRDNVLEG------- : . MMAR_0554|M.marinum_M -------------------------IRAIRTKEYSYIENYVSRPMLDLPK MUL_1217|M.ulcerans_Agy99 -------------------------IRAIRTKEYSYIENYVSRPMLDLPK MAV_4858|M.avium_104 -------------------------IRAIRTKDYSYIENYASRPLLELPW Mb0304c|M.bovis_AF2122/97 -------------------------IRAIRTKEYSYIENYAPRPLLDLPW Rv0296c|M.tuberculosis_H37Rv -------------------------IRAIRTKEYSYIENYAPRPLLDLPW MAB_1547c|M.abscessus_ATCC_199 -------------------------IRAIRTKNYSYIENYAPRPVLDLPW Mflv_5039|M.gilvum_PYR-GCK DRWELYHVDADRSQVHDLAAEYPEKLDELKALWFSEAQKYNGLPLGDLDI TH_0315|M.thermoresistible__bu DRWELYHLESDRSQSRDLAAEHPEKLEELKQLWFDEAAKYNGLPLGDLNL MSMEG_1228|M.smegmatis_MC2_155 -----------------------------CMVWLNEELHAVKWSQFKINF Mvan_4274|M.vanbaalenii_PYR-1 ---------------------------DTGASGLARALKLTSKVPAPLRI : : MMAR_0554|M.marinum_M DIEES------------------PSGLAVAPLVSSP-RPAQELYDLRSDP MUL_1217|M.ulcerans_Agy99 DIEES------------------PSGLAVAPLVSSP-RPAQELYDLRSDP MAV_4858|M.avium_104 DIEES------------------PSGMAVAPLVTAP-RPERELYDLRADP Mb0304c|M.bovis_AF2122/97 DIQES------------------PAGMAVAPLVKAP-RPQRELYDLRADP Rv0296c|M.tuberculosis_H37Rv DIQES------------------PAGMAVAPLVKAP-RPQRELYDLRADP MAB_1547c|M.abscessus_ATCC_199 DIADS------------------PPGRAVATHITGP-RAHRELYDLRTDP Mflv_5039|M.gilvum_PYR-GCK FETMSRWRPTLSGERSAYVYYPGTADVGIGAVVELRGRSFAVLAEVEVDP TH_0315|M.thermoresistible__bu FETLGRWRPHLSRGRTSYTYYPGTAEVGLGAAVDIRGQSFTVLADVTVDA MSMEG_1228|M.smegmatis_MC2_155 KRQQH----------------------FHDPEVPLG---FARITNLLEDP Mvan_4274|M.vanbaalenii_PYR-1 RIPAHTAAN--------------FEGLVIRVDEDAAPGGRGHLWKLVRSF : .: . MMAR_0554|M.marinum_M TETANLLAGEG----------------------AASADTVAAELAALLND MUL_1217|M.ulcerans_Agy99 TETANLLAGEG----------------------AASADPVAAELAALLND MAV_4858|M.avium_104 TEITNLLAGD-----------------------DADADEVAANLAVLLHD Mb0304c|M.bovis_AF2122/97 TETNNLLAGDDS---------------------TQGVAAIAADLAVRLHD Rv0296c|M.tuberculosis_H37Rv TETNNLLAGDDS---------------------TQGVAAIAADLAVRLHD MAB_1547c|M.abscessus_ATCC_199 EEAHNLLGLDA----------------------DEASEAVANDLALRLND Mflv_5039|M.gilvum_PYR-GCK GGANGVVVKHGGAHGGYVMYLQGGRLHFCYNFLGEYEQTLAAPDPVPPGL TH_0315|M.thermoresistible__bu AGAQGVIVKHGAGHGGYVLFLQDGRLHFVYNFMGEEEQRVSSADPIPAGR MSMEG_1228|M.smegmatis_MC2_155 KERE-------------------------------------PVNQTWVRW Mvan_4274|M.vanbaalenii_PYR-1 DDPGTWTEPGVR-----------------------HLAADGIGGPMYRTD MMAR_0554|M.marinum_M WRQSTGDVIPSDFAGSHIAARYTETYLKSHQ-PTPREDSSAAADRDIEG- MUL_1217|M.ulcerans_Agy99 WRQSTGDVIPSDFAGSHIAARYTETYLKSHQ-PTPREDSSAAADRDIEG- MAV_4858|M.avium_104 WRQRTGDVIPSEFAGTRIAARYTETYLQIHHGARPTARSAIAADRGIEEE Mb0304c|M.bovis_AF2122/97 WRQRTADVIPSDFAGSRIAERYTETYLRIHR-KTPTGRSAIAADRGIDEH Rv0296c|M.tuberculosis_H37Rv WRQRTADVIPSDFAGSRIAERYTETYLRIHR-KTPTGRSAIAADRGIDEH MAB_1547c|M.abscessus_ATCC_199 WREKTLDVIPSDFAGTRISERYTETFLRIHG-RPGANRSAIADERGIEQ- Mflv_5039|M.gilvum_PYR-GCK HTLGFTYTVTGTAEGSHTPIGDAELFLDTERVASLAEMRSQPGTFGLAGA TH_0315|M.thermoresistible__bu HILGVSYHRTGTVDGSHTPLGEVALYVDGTVVATRPDVRAHPANFGLAGG MSMEG_1228|M.smegmatis_MC2_155 WVMQHAYRFIQEFEASVEKEQLIPAGAPLDFVPARNP------------- Mvan_4274|M.vanbaalenii_PYR-1 PLDDQWELYDLTDDPVEQHNRWTDPDLHELRAYLRAQLKSVRAESIPERN MMAR_0554|M.marinum_M -------------------------------------------------- MUL_1217|M.ulcerans_Agy99 -------------------------------------------------- MAV_4858|M.avium_104 GNPAQR-------------------------------------------- Mb0304c|M.bovis_AF2122/97 CS------------------------------------------------ Rv0296c|M.tuberculosis_H37Rv CS------------------------------------------------ MAB_1547c|M.abscessus_ATCC_199 -------------------------------------------------- Mflv_5039|M.gilvum_PYR-GCK SLSVGRNNGSPVSEAYHPPFAFAGGRIARVNIDTSGAPYVDLERDFARAF TH_0315|M.thermoresistible__bu GIAVGRNTGQPVSSAYRAPFAFTGGSIAKVIVDISGTPYRDVEREAAMAF MSMEG_1228|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_4274|M.vanbaalenii_PYR-1 RPWPYVRRQPPQPARWSPGRALRRLRD----------------------- MMAR_0554|M.marinum_M --- MUL_1217|M.ulcerans_Agy99 --- MAV_4858|M.avium_104 --- Mb0304c|M.bovis_AF2122/97 --- Rv0296c|M.tuberculosis_H37Rv --- MAB_1547c|M.abscessus_ATCC_199 --- Mflv_5039|M.gilvum_PYR-GCK ARD TH_0315|M.thermoresistible__bu ARD MSMEG_1228|M.smegmatis_MC2_155 --- Mvan_4274|M.vanbaalenii_PYR-1 ---