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TGTRISRVHARRVWDSRGRPTIEAELLLSDGSTGRAIAPAGASRGSGEVTDLRDGGGPFAGYDVTAAVAA ARGLAHHLVDVDAANQQAVDAALTAADQSAEFAAIGGNTAVAMSMAAAHAAAASHGIPLWRYLIGDKPAA MPLPEIQVIGGGAHAARRTDVQDFMVVPAAANTIEEGLNWLAEIHRACGAILSDRGRLAGVADEGGWWPM VDSNEDALELLVASIERAGLQPGTQATIALDIASTEFGSGGRYRLGLDGTELDSDAWSEVLIGWIDKYPI ASIEDPLAEDDPAALAAFTQAVGHRVLVVGDDFTVTDAGRVRRATESGACNGLLVKPNQAGTLSAAKTAH DTAHDCGWDTIVSARSGESEDVTIAHLAVGWGAEQLKVGSITRSERTAKWNELLRIDEQLGGAPIRLGRL SLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0312c | - | - | 100% (424) | enolase (Eno) |
| M. abscessus ATCC 19977 | MAB_1165 | - | 4e-86 | 42.08% (423) | enolase (Eno) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1051 | eno | 2e-89 | 43.30% (418) | phosphopyruvate hydratase |
| M. gilvum PYR-GCK | Mflv_1954 | eno | 1e-86 | 43.57% (420) | phosphopyruvate hydratase |
| M. tuberculosis H37Rv | Rv1023 | eno | 1e-89 | 43.30% (418) | phosphopyruvate hydratase |
| M. leprae Br4923 | MLBr_00255 | eno | 4e-86 | 41.39% (418) | phosphopyruvate hydratase |
| M. marinum M | MMAR_4462 | eno | 6e-88 | 42.58% (418) | enolase Eno |
| M. avium 104 | MAV_1164 | eno | 2e-88 | 43.20% (419) | phosphopyruvate hydratase |
| M. smegmatis MC2 155 | MSMEG_5415 | eno | 3e-89 | 42.11% (418) | phosphopyruvate hydratase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4631 | eno | 3e-88 | 42.58% (418) | phosphopyruvate hydratase |
| M. vanbaalenii PYR-1 | Mvan_4771 | eno | 9e-87 | 42.28% (421) | phosphopyruvate hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4462|M.marinum_M ------------------MPIIEQVGAREILDSRGNPTVEVEVALIDGTF
MUL_4631|M.ulcerans_Agy99 ------------------MPIIEQVGAREILDSRGNPTVEVEVALIDGTF
Mb1051|M.bovis_AF2122/97 ------------------MPIIEQVGAREILDSRGNPTVEVEVALIDGTF
Rv1023|M.tuberculosis_H37Rv ------------------MPIIEQVRAREILDSRGNPTVEVEVALIDGTF
MAV_1164|M.avium_104 ------------------MPIIEQVGAREILDSRGNPTVEVEIALTDGTF
MLBr_00255|M.leprae_Br4923 MSPPTGRPRLSHDYKENLVPVIEQVGAREILDSRGNPTVEVEVVLIDGTF
Mflv_1954|M.gilvum_PYR-GCK ------------------MPIIEQVGAREILDSRGNPTVEVEVGLLDGTV
Mvan_4771|M.vanbaalenii_PYR-1 ------------------MPIIEQVGAREILDSRGNPTVEVEVGLLDGTV
MSMEG_5415|M.smegmatis_MC2_155 ------------------MPIIEQVGAREILDSRGNPTVEVEVALTDGTF
MAB_0312c|M.abscessus_ATCC_199 ----------------MTGTRISRVHARRVWDSRGRPTIEAELLLSDGST
. *.:* **.: ****.**:*.*: * **:
MMAR_4462|M.marinum_M ARAAVPSGASTGEHEAVELRDGGDRYGGKGVKKAVEAVLDEIGPAVIGLN
MUL_4631|M.ulcerans_Agy99 ARAAVPSGASTGEHEAVELRDGGDRYGGKGVKKAVEAVLDEIGPAVIGLN
Mb1051|M.bovis_AF2122/97 ARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLN
Rv1023|M.tuberculosis_H37Rv ARAAVPSGASTGEHEAVELRDGGDRYGGKGVQKAVQAVLDEIGPAVIGLN
MAV_1164|M.avium_104 ARAAVPSGASTGEHEAVELRDGGERYGGKGVQKAVQAVLDEIGPAVIGLN
MLBr_00255|M.leprae_Br4923 ARAAVPSGASTGEYEAVELRDGDGRYGGKGVKRAVDAVLDEIGPVVIGLN
Mflv_1954|M.gilvum_PYR-GCK ARAAVPSGASTGEHEAVELRDGGSRYLGKGVEKAVEAVLDEIAPAVIGLG
Mvan_4771|M.vanbaalenii_PYR-1 SRAAVPSGASTGEHEAVELRDGGSRYLGKGVEKAVEAVLDEIAPAVIGLG
MSMEG_5415|M.smegmatis_MC2_155 ARAAVPSGASTGEHEAVELRDGGSRYGGKGVEKAVEAVLDEIAPQVIGLS
MAB_0312c|M.abscessus_ATCC_199 GRAIAPAGASRGSGEVTDLRDGGGPFAGYDVTAAVAAAR-GLAHHLVDVD
.** .*:*** *. *..:****. : * .* ** *. :. ::.:.
MMAR_4462|M.marinum_M ADDQRLVDQALVDLDGTPDKSRLGGNSILGVSLAVAKAASESAELPLFRY
MUL_4631|M.ulcerans_Agy99 ADDQRLVDQALVDLDGTPDKSRLGGNSILGVSLAVAKAASESAELPLFRY
Mb1051|M.bovis_AF2122/97 ADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRY
Rv1023|M.tuberculosis_H37Rv ADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRY
MAV_1164|M.avium_104 ADDQRLVDQALVDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRY
MLBr_00255|M.leprae_Br4923 ANDQRLIDQELLDLDGTPDKSRLGGNAILGVSLAVAKAAADSAELPLFRY
Mflv_1954|M.gilvum_PYR-GCK ADEQRLVDQALLDLDGTPDKSRLGANAILGVSLAVAKAAAQSAELPLFRY
Mvan_4771|M.vanbaalenii_PYR-1 ADEQRLVDQALVDLDGTPDKSRLGANAILGVSLAVAKAAAQSAELPLFRY
MSMEG_5415|M.smegmatis_MC2_155 ADDQRLVDQALLDLDGTPDKSRLGANAILGVSLAVSKAAAESAGLPLFRY
MAB_0312c|M.abscessus_ATCC_199 AANQQAVDAALTAADQSAEFAAIGGNTAVAMSMAAAHAAAASHGIPLWRY
* :*: :* * * :.: : :*.*: :.:*:*.::**: * :**:**
MMAR_4462|M.marinum_M IGGPNAHILPVPMMNILNGGAHADTGVDIQEFMVAPIGAPSFSEALRWGA
MUL_4631|M.ulcerans_Agy99 IGGPNAHILPVPMMNILNGGAHADTGVDIQEFMVAPIGAPSFSEALRWGA
Mb1051|M.bovis_AF2122/97 VGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGA
Rv1023|M.tuberculosis_H37Rv VGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFVEALRWGA
MAV_1164|M.avium_104 LGGPNAHILPVPMMNILNGGAHADTAVDIQEFMVAPIGAPSFAEALRWGA
MLBr_00255|M.leprae_Br4923 IGGSNAHILPVPMMNILNGGAHADTAVDVQEFMVAPIGAPSFVEALRWGA
Mflv_1954|M.gilvum_PYR-GCK LGGPNAHILPVPMMNIINGGAHADTGVDVQEFMIAPIGAPSFKEALRWGA
Mvan_4771|M.vanbaalenii_PYR-1 VGGPNAHILPVPMMNIINGGAHADTGVDVQEFMIAPIGAPSFKEALRWGA
MSMEG_5415|M.smegmatis_MC2_155 IGGPNAHILPVPMMNILNGGAHADTGVDVQEFMVAPIGAPSFKEALRWGA
MAB_0312c|M.abscessus_ATCC_199 LIGDKPAAMPLPEIQVIGGGAHAARRTDVQDFMVVPAAANTIEEGLNWLA
: * :. :*:* ::::.***** .*:*:**:.* .* :: *.*.* *
MMAR_4462|M.marinum_M EVYHALKAVLKKAGLSTGLGDEGGFAPDVASTTAALDLISQAIEAAGFKP
MUL_4631|M.ulcerans_Agy99 EVYHALKAVLKKAGLSTGLGDEGGFAPDVASTTAALDLISQAIEAAGFKP
Mb1051|M.bovis_AF2122/97 EVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRP
Rv1023|M.tuberculosis_H37Rv EVYHALKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLISRAIESAGLRP
MAV_1164|M.avium_104 EVYHSLKSVLKKEGLSTGLGDEGGFAPDVAGTTAALDLIGRAIESAGFKL
MLBr_00255|M.leprae_Br4923 EVYHALKSVLKKKGLSTGLGDEGGFAPEVAGTTAALDLVTLAIEAAGFKP
Mflv_1954|M.gilvum_PYR-GCK EVYHSLKSVLKKQGLSTGLGDEGGFAPDLPGTKAALDLIGTAIEGAGLKI
Mvan_4771|M.vanbaalenii_PYR-1 EVYHSLKSVLKKQGLATGLGDEGGFAPDLPGTRAALDLIGTAIEAAGLKV
MSMEG_5415|M.smegmatis_MC2_155 EVYHSLKSVLKNQGLATGLGDEGGFAPDVAGTKAALDLISSAIEATGLKL
MAB_0312c|M.abscessus_ATCC_199 EIHRACGAILSDRGRLAGVADEGGWWPMVDSNEDALELLVASIERAGLQP
*:::: ::*.. * :*:.****: * : .. **:*: :** :*::
MMAR_4462|M.marinum_M GVDVALALDAAANEFHADGS--YTFEGTPRTAAQMTEFYAGLLGSYPLVS
MUL_4631|M.ulcerans_Agy99 GVDVALALDAAANEFHADGS--YTFEGTPRTAAQMTEFYAGLLGSYPVVS
Mb1051|M.bovis_AF2122/97 GADVALALDAAATEFFTDGTG-YVFEGTTRTADQMTEFYAGLLGAYPLVS
Rv1023|M.tuberculosis_H37Rv GADVALALDAAATEFFTDGTG-YVFEGTTRTADQMTEFYAGLLGAYPLVS
MAV_1164|M.avium_104 GTDVALALDAAATEFYSDGTG-YKFEGSTRTAEQMAEFYAGLLGAYPLVS
MLBr_00255|M.leprae_Br4923 GADVALALDAAATEFYTDGIG-YHFEGMTHTADQMTEFYADLLGSYPLVS
Mflv_1954|M.gilvum_PYR-GCK GSDVALALDVAATEFYTDGTG-YAFEKETRTAEQMAQFYEQLIGAYPLVS
Mvan_4771|M.vanbaalenii_PYR-1 GSDVALALDVAATEFYTEGTG-YAFEKETRTAEQMAAFYAQLLEAYPLVS
MSMEG_5415|M.smegmatis_MC2_155 GSDVALALDVAATEFYTEGSG-YAFEKETRTAEQMAEFYAGLLDSYPLVS
MAB_0312c|M.abscessus_ATCC_199 GTQATIALDIASTEFGSGGRYRLGLDGTELDSDAWSEVLIGWIDKYPIAS
* :.::*** *:.** : * :: : : . : **:.*
MMAR_4462|M.marinum_M IEDPLYENDWDGWAALTAEIGDRVQIVGDDVFVTNPERLEEGIDRGVANA
MUL_4631|M.ulcerans_Agy99 IEDPLYENDWDGWAALTAEIGDRVQIVGDDVFVTNPERLEEGIDRGVANA
Mb1051|M.bovis_AF2122/97 IEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANA
Rv1023|M.tuberculosis_H37Rv IEDPLSEDDWDGWAALTASIGDRVQIVGDDIFVTNPERLEEGIERGVANA
MAV_1164|M.avium_104 IEDPLSEDDWDGWAALTASIGDRVQLVGDDVFVTNPERLEEGIEKGVANA
MLBr_00255|M.leprae_Br4923 IEDPLSEDDWDGWAALTASIGEQVQIVGDDIFATNPERLEEGIGRGVANA
Mflv_1954|M.gilvum_PYR-GCK IEDPLSEDDWDGWVALTSAIGDRVQLVGDDLFVTNPERLEDGIERGAGNA
Mvan_4771|M.vanbaalenii_PYR-1 IEDPLSEDDWDGWVALTAAIGDKVQLVGDDLFVTNPERLEDGIERGAANA
MSMEG_5415|M.smegmatis_MC2_155 IEDPLSEDDWDGWVSLTAAIGDRIQLVGDDLFVTNPERLEDGIQRGAANA
MAB_0312c|M.abscessus_ATCC_199 IEDPLAEDDPAALAAFTQAVGHRVLVVGDDFTVTDAGRVRRATESGACNG
***** *:* . .::* :*.:: :****. .*:. *:. . *. *.
MMAR_4462|M.marinum_M LLVKVNQIGTLTETLDAVALAHHSGYRTMISHRSGETEDTIIADLAVAVG
MUL_4631|M.ulcerans_Agy99 LLVKVNQIGTLTETLDAVALAHHSGYRTMISHRSGETEDTIIADLAVAVG
Mb1051|M.bovis_AF2122/97 LLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIG
Rv1023|M.tuberculosis_H37Rv LLVKVNQIGTLTETLDAVTLAHHGGYRTMISHRSGETEDTMIADLAVAIG
MAV_1164|M.avium_104 LLVKVNQIGTLTETLDAVALAHHSGYRTMMSHRSGETEDTTIADLAVAVG
MLBr_00255|M.leprae_Br4923 LLVKVNQIGTLTETLEAVALAHHSGYRTMISHRSGETEDTMIADLVVALG
Mflv_1954|M.gilvum_PYR-GCK LLVKVNQIGTLTETLDAVSLAHHAGYKTMMSHRSGETEDTTIADLAVAVG
Mvan_4771|M.vanbaalenii_PYR-1 LLVKVNQIGTLTETLDAVSLAHNAGYKTMMSHRSGETEDTTIADLAVAVG
MSMEG_5415|M.smegmatis_MC2_155 LLVKVNQIGTLTETLDAVSLAHNSGYRTMMSHRSGETEDTTIADLAVAVG
MAB_0312c|M.abscessus_ATCC_199 LLVKPNQAGTLSAAKTAHDTAHDCGWDTIVSARSGESEDVTIAHLAVGWG
**** ** ***: : * **. *: *::* ****:**. **.*.*. *
MMAR_4462|M.marinum_M SGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFVADPK
MUL_4631|M.ulcerans_Agy99 SGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFVADPK
Mb1051|M.bovis_AF2122/97 SGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
Rv1023|M.tuberculosis_H37Rv SGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFACETK
MAV_1164|M.avium_104 SGQIKTGAPARSERVAKYNQLLRIEEALGDAARYAGDLAFPRFALETR
MLBr_00255|M.leprae_Br4923 SGQIKTGAPARSERVAKYNQLLRIEEELGDAARYAGDLAFLRYVVETR
Mflv_1954|M.gilvum_PYR-GCK SGQIKTGAPARSERVAKYNQLLRIEEELGDAARYAGDLAFPRFGVESK
Mvan_4771|M.vanbaalenii_PYR-1 SGQIKTGAPARSERVAKYNQLLRIEEELGDAARYAGDLAFPRFSVETK
MSMEG_5415|M.smegmatis_MC2_155 SGQIKTGAPARSERVAKYNQLLRIEETLGDAARYAGDLAFPRLEAK--
MAB_0312c|M.abscessus_ATCC_199 AEQLKVGSITRSERTAKWNELLRIDEQLGGAPIRLGRLSLG-------
: *:*.*: :****.**:*:****:* **.*. * *::