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VTDCRDLVRPAAAAQRLPSGDLDTSLVSGHERGRRAAAFASGGVLVVGAVAALHNLYRSGDDAAELIAWS GLLLLALTALGGGIKLAMWGARPVIAALFDRAKERLAEPVLAVVASGAVIVGALGMWWTFRGGYAGWWQQ LSGESQWSLSLGVGQMLVAVLAGAALFTGGRYVTGLAREALTESGLLIERDRAAGRRRVPEGLWHPGLVA ALVGGGLALVVMTAWLTPKVGPTIVGANTLAAVAAIVAVLVWGVGANLGWWKGLAGLWKWATDASHKAAA TSGVVALLMFSAGGLGLGWFTPATVPQAHAQCPPDCGGGSNGSGSYGPDASQFQPPQMPGQMPDYQGGIN QPPLDQNSSISIYNTQAPSVSNNGVQGSSGQQGPQQGWDQPAHGTQIPDYQNAAPYTQGPGRPNPDFNPG SDAGSQGGQSNQGAQQPVQQPQQASQQPPQQDAGQQPNQSPNQSSDQQKIDDLTRQLQDQQQLSSQDRQR IDDLTKQLQQGQQRQNGNQKLPKAPSRDKKQDDKDQQDRDDQSGDNDLSALLLGAASTRRRKQDEQDLSD QQQPQGPDTQALAQDGAQLGQSLPGDIANTVSDSVNLGQSAGSAAQNFGSAAQAGASLASSAQSGAVNPM DAVALVQGVSGGISDTADAVGSGASIASTWLNEAGQGAQLAADANPQLKAEAEQVRQLTQAGSQVADLTG KVAGGVSQVSGMVNTASSLGTSGMPDTSGATDALSGTATAVNGPGDVPKPPTPPSVPSQSPSSVQALDST TTRAPQQPPQPSNPSTPKTANQSSTSKPLSPLEASTFPAPLQALNTAQAASTPDPNAGRLSSMPGVRDVS QPPLRPAPTLQPDQVDAFRAITRQNLENQNVPADQIEQRVNDAVKQAQTPRFMPDPQPMRTPGAQPLDRP LGDKFNDVMGRANDRAYDDIDGLGQLGKNLTGQGGPGAPGVAESWKDLGTNTVKGLPDAVGGGFVADGKR LYEEPGNFIGDKMVELPLAAVSVPLGGEGAAIERGVLGDLASTETKAVTRGPVETPPVQLPAVDVPKPRL ADYFQPGSPPKASELEKYALSQGWKKSQTPSGPAKYSDNNGIVRMTIKEGSQRAPGSELPHVELRDPNGQ RIDPFGNPVARKSPDNHTAIGWDW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_0209 | - | - | 100% (1144) | hypothetical protein MAB_0209 |
M. abscessus ATCC 19977 | MAB_1555 | - | 0.0 | 67.27% (1042) | hypothetical protein MAB_1555 |
M. abscessus ATCC 19977 | MAB_4810c | - | 6e-81 | 37.10% (628) | hypothetical protein MAB_4810c |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3906 | - | 4e-08 | 30.30% (165) | hypothetical protein Mb3906 |
M. gilvum PYR-GCK | Mflv_3843 | - | 1e-06 | 24.01% (554) | hypothetical protein Mflv_3843 |
M. tuberculosis H37Rv | Rv3876 | - | 5e-08 | 30.30% (165) | hypothetical protein Rv3876 |
M. leprae Br4923 | MLBr_00048 | - | 2e-07 | 27.72% (184) | hypothetical protein MLBr_00048 |
M. marinum M | MMAR_0884 | - | 3e-07 | 21.69% (355) | hypothetical protein MMAR_0884 |
M. avium 104 | MAV_0290 | - | 1e-07 | 22.35% (434) | hypothetical protein MAV_0290 |
M. smegmatis MC2 155 | MSMEG_5700 | - | 3e-08 | 24.78% (339) | secreted protein |
M. thermoresistible (build 8) | - | - | - | - | - |
M. ulcerans Agy99 | MUL_0637 | - | 6e-06 | 20.85% (355) | hypothetical protein MUL_0637 |
M. vanbaalenii PYR-1 | Mvan_0085 | - | 6e-09 | 24.49% (245) | hypothetical protein Mvan_0085 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 -------------------------------------------------- Mflv_3843|M.gilvum_PYR-GCK MSRTKKSIVVVMMGSAGLFLSAPLLGPAANATPTRGGVPCVGILQQIVTR MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 --------------------------------MTDCRDLVRPAAAAQRLP Mflv_3843|M.gilvum_PYR-GCK PGEIPQALTDTARSFTEPPKPAPPVVRPPASSSSSAGTPPVPGRPPASVV MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 --------------------------------MAQFGGLASPIPDPTPQP Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 SGDLDTSLVSGHERGRRAAAFASGGVLVVGAVAALHNLYRSGDDAAELIA Mflv_3843|M.gilvum_PYR-GCK TPSSGATPPVPPSPGTPASTSTRGGTPPVPPAPPAPAGTPASGATPPAPP MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 HGAASTTDIPVRGTPDAADTKPEPATESKPDAEEKRRPNRDGKTPADPKP Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 WSGLLLLALTALGGGIKLAMWGARPVIAALFDRAKERLAEPVLAVVASGA Mflv_3843|M.gilvum_PYR-GCK VPGVPAVTSTG-GGTPPVPPVPGAPVGAPVANPGLPTPPVPGAPVFGDGG MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 VPDAGEKPDTDEKPKPDVDKAEPKAKVKDIG------------QVTANDK Mvan_0085|M.vanbaalenii_PYR-1 -----------------------------------------------MGI MMAR_0884|M.marinum_M --------------------------------MDVVLGVAIAGP---IAR MUL_0637|M.ulcerans_Agy99 -------------------MLVAGWPAEGEPQMDVVLGVAIAGP---IAR Mb3906|M.bovis_AF2122/97 ------------------------MAADYDKLFRPHEGMEAPDD---MAA Rv3876|M.tuberculosis_H37Rv ------------------------MAADYDKLFRPHEGMEAPDD---MAA MLBr_00048|M.leprae_Br4923 ------------------------MAADYDKLFRLDDGAYASPD---QAA MAB_0209|M.abscessus_ATCC_1997 VIVGALGMWWTFRGG--YAGWWQQLSGESQWSLSLGVGQMLVAV---LAG Mflv_3843|M.gilvum_PYR-GCK AVLPPLPPAPAGPAGGPAGLVAPPAPPVPGGPAAVPAGVALPPAPPGAPG MSMEG_5700|M.smegmatis_MC2_155 ----------------------------MSGRHRKPTSSSSAKN---VAK MAV_0290|M.avium_104 VSTIGKSFGKAYLEAAKSPIKGIPAIVKAEYKAGTALGEKLAGK---IAG Mvan_0085|M.vanbaalenii_PYR-1 SKNVGEYVEEMTEPAGWPHVDEDHLYTRASGFVDKVTQLIAVRDSWQQQQ MMAR_0884|M.marinum_M LALVGAAAEGS--------------------------------------- MUL_0637|M.ulcerans_Agy99 LALVGAAAEGS--------------------------------------- Mb3906|M.bovis_AF2122/97 QPFFDPSASFP--------------------------------------- Rv3876|M.tuberculosis_H37Rv QPFFDPSASFP--------------------------------------- MLBr_00048|M.leprae_Br4923 EQLFDDAPLYP--------------------------------------- MAB_0209|M.abscessus_ATCC_1997 AALFTGGRYVTGLAREALTESGLLIERDRAAGRRRVPEGLWHPGLVAALV Mflv_3843|M.gilvum_PYR-GCK APVFGEAGAAPSG----AAAPVAPAAGSGGAGGAGGGSGIGGPGGGGAPV MSMEG_5700|M.smegmatis_MC2_155 IAFTG--------------------------------------------- MAV_0290|M.avium_104 EGLLKSASRVS--------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 ARLFGGGAWSG--------------------------------------- . MMAR_0884|M.marinum_M -----AVIDQSSVDLAEGPVAVLTETIVGTNQLLADEGHHLVATRLCWSD MUL_0637|M.ulcerans_Agy99 -----AVIDQSSVDLAEGPVAVLTETIVGTNQLLADEGHHLVATRLCWSD Mb3906|M.bovis_AF2122/97 -----PAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTP Rv3876|M.tuberculosis_H37Rv -----PAPASANLPKPNGQTPPPTSDDLSERFVSAPPPPPPPPPPPPPTP MLBr_00048|M.leprae_Br4923 -----PPIIPTCTTTPNGEVASPMPD-----WSEQLPPNPPAASKSPLPP MAB_0209|M.abscessus_ATCC_1997 GGGLALVVMTAWLTPKVGPTIVGANTLAAVAAIVAVLVWGVGANLGWWKG Mflv_3843|M.gilvum_PYR-GCK EGTGGAVPAGAPLAAAGGEVPPPAPPIPGAPVIGEAGVVPPPAPPAPAPP MSMEG_5700|M.smegmatis_MC2_155 -----AVLGGGGLGMAGQAMAATDGEWDQVARCESGGNWAINTGNG---- MAV_0290|M.avium_104 ----LKTAGRLVPGVGTAIGVISAYKNFEQGDYVGAAINMVSAIPGPIGW Mvan_0085|M.vanbaalenii_PYR-1 ---AAANAAETAIQARVSEMISLINHLEKAIAWYTMTARTIAQTKATINQ MMAR_0884|M.marinum_M QD-----RAEDLRRALDDSGVLDVAVLSE---------SEAVTALLGPAH MUL_0637|M.ulcerans_Agy99 QD-----RAEDLRRALDDSGVLDVAVLSE---------SEAVTALLGPAH Mb3906|M.bovis_AF2122/97 MP-----IAAGEPPSPEP--AASKPPTPP---------MPIAGPEPAPPK Rv3876|M.tuberculosis_H37Rv MP-----IAAGEPPSPEP--AASKPPTPP---------MPIAGPEPAPPK MLBr_00048|M.leprae_Br4923 MP-----IGSSVQPPP----ASSESPRAP---------MPVSAP---PRS MAB_0209|M.abscessus_ATCC_1997 LAGLWKWATDASHKAAATSGVVALLMFSA---------GGLGLGWFTPAT Mflv_3843|M.gilvum_PYR-GCK AGGLGGAVPPPVPGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPA MSMEG_5700|M.smegmatis_MC2_155 -------YHGGLQFSPSTWRAHGGTEFAP--------------AAYMATK MAV_0290|M.avium_104 VG-----IAASTAWEAFDLGGNKIGQWDS---------PDGSTTHILPAA Mvan_0085|M.vanbaalenii_PYR-1 NLETSYSFIASIRASPELDEVEKDGIIQS--------WVQSQRAVNTVTV MMAR_0884|M.marinum_M AGSAVLLVG-------------------------EET------------- MUL_0637|M.ulcerans_Agy99 AGSAVLLVG-------------------------EET------------- Mb3906|M.bovis_AF2122/97 PPTPPMPIA-------------------------GPEPAPPKPPTPPMPI Rv3876|M.tuberculosis_H37Rv PPTPPMPIA-------------------------GPEPAPPKPPTPPMPI MLBr_00048|M.leprae_Br4923 PAASLMPIS-------------------------EPPQWPP--------- MAB_0209|M.abscessus_ATCC_1997 VPQAHAQCPPDC----------------GGGSNGSGSYGPDASQFQPPQM Mflv_3843|M.gilvum_PYR-GCK PGAPGVPVVDEAGVVTPPAPGGPGVPTGGEGGVVTPPAPGAPGAPVVDEA MSMEG_5700|M.smegmatis_MC2_155 EEQIAVAER----------------------------------------- MAV_0290|M.avium_104 AHDIGGVTALDS-----------------------------QLREAQQCV Mvan_0085|M.vanbaalenii_PYR-1 LTAAGDVAAFDS-------------------------------------- MMAR_0884|M.marinum_M -ASLSVLGGGDAPPTMLAAAPVEGDATSTFDTLMA-HLDDQGGAPGEVLL MUL_0637|M.ulcerans_Agy99 -ASLSVLGGGDAPPTMLAAAPVEGDATSTFDTLMT-HLDDEGGAPGEVLL Mb3906|M.bovis_AF2122/97 AGPAPTPTESQLAPPRPPTPQTPTGAPQQPESPAP-HVPSHGPHQPRRTA Rv3876|M.tuberculosis_H37Rv AGPAPTPTESQLAPPRPPTPQTPTGAPQQPESPAP-HVPSHGPHQPRRTA MLBr_00048|M.leprae_Br4923 -AEAPEHQFAKAEPPSVPIPINEP-SPAKPATPMP-MTPIDGSQRTPVTS MAB_0209|M.abscessus_ATCC_1997 PGQMPDYQGGINQPPLDQNSSISIYNTQAPSVSNN-GVQGSSGQQGPQQG Mflv_3843|M.gilvum_PYR-GCK GVVTPPAPGGPGVPAVGDTAVVTPPAPGAPGTPAVNSVETFSPPAPPAAT MSMEG_5700|M.smegmatis_MC2_155 --VLASQGKGAWPTCGRGLSGATPRNVVAEPEPAPLDAPGVNGELPPPAP MAV_0290|M.avium_104 FSFQDGPRGKVWDSNPPEALRLDGADIQKEIAEALGGISDLFAEVDRVMS Mvan_0085|M.vanbaalenii_PYR-1 -WQPPPSPQRIPATLSPPESVSAPSGPEPPKQNVGYFGPTRPPAAEPRGG . MMAR_0884|M.marinum_M VGSSEHTTVIADQFRDAS----TMRVEVPEDPTFALARGAAMAAAGAGST MUL_0637|M.ulcerans_Agy99 VGSSEHTTVIADQFRDAS----TMRVEVPEDPTFALARGAAMAAAGAGST Mb3906|M.bovis_AF2122/97 PAPPWAKMPIGEPP-PAP---SRPSASPAEPPTRPAPQHSRRARRGHRYR Rv3876|M.tuberculosis_H37Rv PAPPWAKMPIGEPP-PAP---SRPSASPAEPPTRPAPQHSRRARRGHRYR MLBr_00048|M.leprae_Br4923 PEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRPSANQHSRHARRGHHHR MAB_0209|M.abscessus_ATCC_1997 WDQPAHGTQIPDYQNAAPYTQGPGRPNPDFNPGSDAGSQGGQSNQGAQQP Mflv_3843|M.gilvum_PYR-GCK PPSSGSVETFSPPAPPAPGTGTNSTVEISTPPPPGTPGLPSEGSTTYTTP MSMEG_5700|M.smegmatis_MC2_155 VDMLAAPMPAPEGLPPAPEALPPAPEALPPAPEAPAPAPEALPPAPEALP MAV_0290|M.avium_104 SAGEAYFDEYKARLQPHLEAMAALKEQVKPFTQQLGNASDGAATAYTAVL Mvan_0085|M.vanbaalenii_PYR-1 SAGLSAKAANDAYMAQGPSASADQPVPISQSSGGGSPGSPGGLGSPGSPS . MMAR_0884|M.marinum_M MAQQVLGG------DAGEATTYLPPELAATASGQD--------------- MUL_0637|M.ulcerans_Agy99 MAQQVLGG------DAGEATTYLPPELAATASGQD--------------- Mb3906|M.bovis_AF2122/97 TDTERNVG------KVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQP Rv3876|M.tuberculosis_H37Rv TDTERNVG------KVATGPSIQARLRAEEASGAQLAPGTEPSPAPLGQP MLBr_00048|M.leprae_Br4923 DETQQANP------ASATEPMIAPRARTAELRQAP--------------- MAB_0209|M.abscessus_ATCC_1997 VQQPQQASQQPPQQDAGQQPNQSPNQSSDQQKIDDLTRQLQDQQQLSSQD Mflv_3843|M.gilvum_PYR-GCK PTPEITLNPANSGIDIATPPAPGLPGAPLEATANITTPGTPGVPGAPVNS MSMEG_5700|M.smegmatis_MC2_155 PAPEALPP-------APEAPAPAPEALPP--------------------- MAV_0290|M.avium_104 DANRAAREQLVADGKLSDQGPASTFTSAVSAAGSQVTAADQN-------- Mvan_0085|M.vanbaalenii_PYR-1 SSTSGSSP------ISTSGGSSSGSGASSSGSGSG--------------- . MMAR_0884|M.marinum_M ------EDEQLAYSQAGENELLPVTGADEYGDYGPDDDEFADDYED---- MUL_0637|M.ulcerans_Agy99 ------EDEQLAYSQAGENELLPVTGADEYGDYGPDDDEFADDYED---- Mb3906|M.bovis_AF2122/97 RSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQP---- Rv3876|M.tuberculosis_H37Rv RSYLAPPTRPAPTEPPPSPSPQRNSGRRAERRVHPDLAAQHAAAQP---- MLBr_00048|M.leprae_Br4923 ---------HAAAEPAPTQHLTR-----------PDGLVSHRTALH---- MAB_0209|M.abscessus_ATCC_1997 RQRIDDLTKQLQQGQQRQNGNQKLPKAPSRDKKQDDKDQQDRDDQSGDND Mflv_3843|M.gilvum_PYR-GCK SIDVATPGEVGVPAAPIERSMTVTTPDTPGAPGAPANAAVDVATPPAP-- MSMEG_5700|M.smegmatis_MC2_155 ---------------------------------APEAPAPVAEALP---- MAV_0290|M.avium_104 -------IANLFGEPAAVLTATVASGTGTRIDPSKKGAPVQTTASP---- Mvan_0085|M.vanbaalenii_PYR-1 ----------SGGSSSAAASSSGTSPTSGGQSATGAAGGQPTAASP---- MMAR_0884|M.marinum_M ----------------------EAPAGTRLSSRSLLISNAVVAFAVIGFA MUL_0637|M.ulcerans_Agy99 ----------------------EAPAGTRLSSRSLLISNAVVAFAVIGFA Mb3906|M.bovis_AF2122/97 ----------------------DSITAATTGGRRRKRAAPDLDATQKSLR Rv3876|M.tuberculosis_H37Rv ----------------------DSITAATTGGRRRKRAAPDLDATQKSLR MLBr_00048|M.leprae_Br4923 ----------------------DSTATSAIG-------------VQTGRS MAB_0209|M.abscessus_ATCC_1997 LSALLLGAASTRRRKQDEQDLSDQQQPQGPDTQALAQDGAQLGQSLPGDI Mflv_3843|M.gilvum_PYR-GCK ----------------------GVPGAPVVGEAGVTTPGAPGAPGAPANA MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 --------------------AAQTPVTPTSQTPTVTPKTETPAKTTDALG Mvan_0085|M.vanbaalenii_PYR-1 -----------------------ASAAKAQPSPMQQMVNQAPPPLASSAP MMAR_0884|M.marinum_M SLAVAVAVAIRPTASSEPVEGHQNAQPGKFMPLLPTQQQAPVPPPPPD-- MUL_0637|M.ulcerans_Agy99 SLAVAVAVAIRPTAASEPVEGHQNAQPGKFMPLLPTQQQAPVPPPPPD-- Mb3906|M.bovis_AF2122/97 PAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDE-- Rv3876|M.tuberculosis_H37Rv PAAKGPKVKKVKPQKPKATKPPKVVSQRGWRHWVHALTRINLGLSPDE-- MLBr_00048|M.leprae_Br4923 TGAK---------------KPSKVVAKRGWRHWVHTVTRINLGLSPDE-- MAB_0209|M.abscessus_ATCC_1997 ANTVSDSVNLGQSAGSAAQNFGSAAQAG--ASLASSAQSGAVNPMDAV-- Mflv_3843|M.gilvum_PYR-GCK AVDVATPPAPGVPGAPVVGEAAVTTPGAPGVPGVPAGGDAGVVTPPAPGV MSMEG_5700|M.smegmatis_MC2_155 ------PAPEALPPAPEAPPAPEALPPAPEAQIVDASLQVPADVPPAP-- MAV_0290|M.avium_104 DLLRSLNQKQQMPTTPSTPNLGNGLGSGSPLGTGGSPLSTSPSKPLDTSS Mvan_0085|M.vanbaalenii_PYR-1 ATSPAPAPAPSQPAAAPSAAAGAGPSSGGVGGISASAGSAPVGAAPPSGA : MMAR_0884|M.marinum_M --APTAGFQGGTIPTVQGV-----------VPRQATPTVPAPVAPAPAPA MUL_0637|M.ulcerans_Agy99 --APTAGFQGGTIPTVQGV-----------VPRQATPTVPGPVAPAPAAA Mb3906|M.bovis_AF2122/97 --KYELDLHARVRRNPRGS-----------YQIAVVGLKGGAGKTTLTAA Rv3876|M.tuberculosis_H37Rv --KYELDLHARVRRNPRGS-----------YQIAVVGLKGGAGKTTLTAA MLBr_00048|M.leprae_Br4923 --RYELDLRTRVRRPPRGS-----------YQIGILGLKGGAGKTTVTVT MAB_0209|M.abscessus_ATCC_1997 --ALVQGVSGGISDTADAVGSGASIASTWLNEAGQGAQLAADANPQLKAE Mflv_3843|M.gilvum_PYR-GCK PGAPVVGEAGVTTPGAPGVPG------VPAGGDAGVVTPPAPGVPGAPAA MSMEG_5700|M.smegmatis_MC2_155 ----------PVEPAPPAP------------VDAVAAPENQNWDQAPAPA MAV_0290|M.avium_104 DRKLDDGRKGEEKKEERKLAE---------PKKEKSETKPSLAASKTDNA Mvan_0085|M.vanbaalenii_PYR-1 PPAPPVPLGPPTSPAPPGPVP---------PTGTPGTAPGGAMGPGVAPM MMAR_0884|M.marinum_M PGVVPAPIPLPIPIIIPPWPNWS-----PGMPTPSTVTVTPTTPTTTAPS MUL_0637|M.ulcerans_Agy99 PGVVPAPIPLPIPIIIPPWPNWS-----PGMPTPSTVTVTPTTPTTTAPS Mb3906|M.bovis_AF2122/97 LGSTLAQVRADRILALDADPGAGNLADRVGRQSGATIADVLAEKELSHYN Rv3876|M.tuberculosis_H37Rv LGSTLAQVRADRILALDADPGAGNLADRVGRQSGATIADVLAEKELSHYN MLBr_00048|M.leprae_Br4923 LGSMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLADKDVKSYN MAB_0209|M.abscessus_ATCC_1997 AEQVRQLTQAGSQVADLTGKVAGGVSQVSGMVNTASSLGTSGMPDTSGAT Mflv_3843|M.gilvum_PYR-GCK TEAGLATPPGPGAPGAPVVGDAGVATPPGPGVPGAPIVDEAGLATPPAPV MSMEG_5700|M.smegmatis_MC2_155 DQPQTWALHVGGPLPLDPVLPAPAPAPAPAPAPGAPAAVAAPAPDPLAPA MAV_0290|M.avium_104 KAPESKLATAEKPGAHTAAVPAQPSAAAAAANPAAPAAQGQSAPPEQSKQ Mvan_0085|M.vanbaalenii_PYR-1 STTGTAGGAAPAPIPVSTARAERDAIAAASTAGALRRKTNGADPLQQARH MMAR_0884|M.marinum_M TVTPTTPTTTAPSTVTPTTPTTTAPSTLTP------TTPTTTVPS----- MUL_0637|M.ulcerans_Agy99 TLTPTTPTTTAPSTLTPSTPTTTAPSTLTP------TTPTTTVPS----- Mb3906|M.bovis_AF2122/97 DIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADPASRFYN----- Rv3876|M.tuberculosis_H37Rv DIRAHTSVNAVNLEVLPAPEYSSAQRALSDADWHFIADPASRFYN----- MLBr_00048|M.leprae_Br4923 DIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVSKYYN----- MAB_0209|M.abscessus_ATCC_1997 DALSGTATAVNGPGDVPKPPTPPSVPSQSPSSVQALDSTTTRAPQQPPQP Mflv_3843|M.gilvum_PYR-GCK APVEGAGGAVPPAGPPPAPVFGDAGAPVEAAAGGAPVEAAAGVTGGGSVA MSMEG_5700|M.smegmatis_MC2_155 PNADVAPTPPEGVPHLASPENLPPG----------TTETPDQIPG----- MAV_0290|M.avium_104 VDVKGTRVEFPDAKTAKLASLLANADPAHP----LSLAEAAKMAG----- Mvan_0085|M.vanbaalenii_PYR-1 IAAALNVGIMDFGFFWVTGVTMEGTIVVANSYGLAYIPAGVALPDQVR-- MMAR_0884|M.marinum_M ----------------TVITPTTTAPITPTT--VAPTTVNPTTVAPTTVA MUL_0637|M.ulcerans_Agy99 ----------------TVITPTTTAPITPIT--VAPTTVNPTTVAPTTVA Mb3906|M.bovis_AF2122/97 ----------------LVLADCGAGFFDPLTRGVLSTVSGVVVVASVSID Rv3876|M.tuberculosis_H37Rv ----------------LVLADCGAGFFDPLTRGVLSTVSGVVVVASVSID MLBr_00048|M.leprae_Br4923 ----------------VMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVD MAB_0209|M.abscessus_ATCC_1997 SN---------PSTPKTANQSSTSKPLSPLEASTFPAPLQALNTAQAAST Mflv_3843|M.gilvum_PYR-GCK GAGAGGGAGGAAGGAGVEGASGAVGAAGGPGAGAAPAAAGGAAPGGAPGG MSMEG_5700|M.smegmatis_MC2_155 ------------------QGPNMTYLREIWHAIQTQDISGKDALLALTQR MAV_0290|M.avium_104 ------------------LTPPVPGQDPGSQVAPAQAKPGDLLVAGDKKY Mvan_0085|M.vanbaalenii_PYR-1 --------------MATADESIPAGERAKWATYPILAVQGWAQHHNQQLR MMAR_0884|M.marinum_M PTTQQTVVPQPTQET-VAPLPTQQTVAPQP-------TIAPQ-------P MUL_0637|M.ulcerans_Agy99 PTTQQTVVPQPTQET-VAPPPTQQTVAPQP-------TIAPQ-------P Mb3906|M.bovis_AF2122/97 GAQQASVALDWLRNNGYQDLASRACVVINH-------IMPGE-------P Rv3876|M.tuberculosis_H37Rv GAQQASVALDWLRNNGYQDLASRACVVINH-------IMPGE-------P MLBr_00048|M.leprae_Br4923 AARQAAIALDWLRHNGYQDLLSRACVVINH-------VMPKE-------P MAB_0209|M.abscessus_ATCC_1997 PDPNAGRLSSMPGVRDVSQPPLRPAPTLQPDQVDAFRAITRQNLENQNVP Mflv_3843|M.gilvum_PYR-GCK PVAGGGPVGGPGALPAPGAPIVGEAGVVSPPAPGVPGGAAAVPAGAVTPP MSMEG_5700|M.smegmatis_MC2_155 PLTTPDVPGGAAPNRPVAPPPAPGDPALAP-------------------- MAV_0290|M.avium_104 MLLEPGKFYDLQEYKVVSADQLPQDAGSRG-------------------G Mvan_0085|M.vanbaalenii_PYR-1 AVVATEEQFANFDPGVAKIILTQDDIPESG-------------------Q MMAR_0884|M.marinum_M TQQAPEPPSGGSSGGSSGGGSSSGG-GSSSGGGSSSGGGSSSGGGSSS-- MUL_0637|M.ulcerans_Agy99 TQQALEPPSGGSSGGSSGGGSSSGG-GSSSGGGSSSG------------- Mb3906|M.bovis_AF2122/97 NVAVKDLVRHFEQQVQPGRVVVMPW-DRHIAAGTEISLDLLDP------- Rv3876|M.tuberculosis_H37Rv NVAVKDLVRHFEQQVQPGRVVVMPW-DRHIAAGTEISLDLLDP------- MLBr_00048|M.leprae_Br4923 NIASKDLVQQFEQQIQPGRVVVLPW-DKHIAAGTEIRLDRLDP------- MAB_0209|M.abscessus_ATCC_1997 ADQIEQRVNDAVKQAQTPRFMPDPQ-PMRTPGAQPLDRPLGDKFNDVMGR Mflv_3843|M.gilvum_PYR-GCK APGVPGAPVFGEAGVVTPPAPGVPGGAAAVPAGVVTPPAPGVPGGAAAVP MSMEG_5700|M.smegmatis_MC2_155 -----APAPLGAPAPAPAPEPAPVG--APAPVGAPVPPPA---------- MAV_0290|M.avium_104 YFHLNDPSPTGAPGTQPVSGQTPGGVDQAVPGGTPPPAAPADATP----- Mvan_0085|M.vanbaalenii_PYR-1 MQGRSRLEVIAPEAAQRLSAVSDFGLNDLLPPATADLEPPADDS------ . MMAR_0884|M.marinum_M ---------GGGSSSGGGSSSGGGSSSGGGSSSGGGSSSGRGSSSGGSSS MUL_0637|M.ulcerans_Agy99 ----------------------------------------RGSSSGGSSS Mb3906|M.bovis_AF2122/97 ------------------------------------IYKRKVLELAAALS Rv3876|M.tuberculosis_H37Rv ------------------------------------IYKRKVLELAAALS MLBr_00048|M.leprae_Br4923 ------------------------------------LYRRRILELAAALS MAB_0209|M.abscessus_ATCC_1997 ANDRAYDDIDGLGQLGKNLTGQGGPGAPGVAESWKDLGTNTVKGLPDAVG Mflv_3843|M.gilvum_PYR-GCK AGAVTPPAPGVPGAPVFGDAGVATPPVPGVPGGGTTVPAASVTPPAPGVP MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 ------------------------------------QKPHDPAAGAPAPS Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------ARLWFEVAKPLMS MMAR_0884|M.marinum_M GGHSSGGGS----------------------------------------- MUL_0637|M.ulcerans_Agy99 GGHSSGGGS----------------------------------------- Mb3906|M.bovis_AF2122/97 DDFERAGRR----------------------------------------- Rv3876|M.tuberculosis_H37Rv DDFERAGRR----------------------------------------- MLBr_00048|M.leprae_Br4923 DDFERAGRH----------------------------------------- MAB_0209|M.abscessus_ATCC_1997 GGFVADGKRLYEEPGNFIGDKMVELPLAAVSVPLGGEGAAIERGVLGDLA Mflv_3843|M.gilvum_PYR-GCK GGASTVPGNAGTPSTPGLPPGSTDTYINYPAPPVPPTPPNSTGVSAGTPG MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 GGVPSAGTPG------------------APKPTATGGGPSSAEATQTGVG Mvan_0085|M.vanbaalenii_PYR-1 TNPQRSGPHLQAFVAYAKHAQELALHKAHNAAEPGDQRLAIADWVYWQHL MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 STETKAVTRGPVETPPVQLPAVDVPKPRLADYFQPGSPPKASELEKYALS Mflv_3843|M.gilvum_PYR-GCK SPAPGTPGSTLTLTDLLTPPGIARTLQNTASSVMGATPPGTPPVPGGSGS MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 QPSPSPSTSALDPTAVR--------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 EVLLTDAVSTDAAV------------------------------------ MMAR_0884|M.marinum_M -------------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 QGWKKSQTPSGPAKYSDNNGIVRMTIKEGSQRAPGSELPHVELRDPNGQR Mflv_3843|M.gilvum_PYR-GCK VSLAVPGTPSPIAPLAATGLSNLVSPPSLTIPSIPGLPVPLPNTVPVPSD MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------------- MAV_0290|M.avium_104 -------------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_0884|M.marinum_M -------------------------------------------- MUL_0637|M.ulcerans_Agy99 -------------------------------------------- Mb3906|M.bovis_AF2122/97 -------------------------------------------- Rv3876|M.tuberculosis_H37Rv -------------------------------------------- MLBr_00048|M.leprae_Br4923 -------------------------------------------- MAB_0209|M.abscessus_ATCC_1997 IDPFGNPVARKSPDNHTAIGWDW--------------------- Mflv_3843|M.gilvum_PYR-GCK LLCVGTDWSASQGDSAATPPAAEVPRVVTGAAPTGDRRDRWGNR MSMEG_5700|M.smegmatis_MC2_155 -------------------------------------------- MAV_0290|M.avium_104 -------------------------------------------- Mvan_0085|M.vanbaalenii_PYR-1 --------------------------------------------