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M. thermoresistible (build 8) TH_3175 (-)

annotation: biotin carboxylation domain protein
coordinates: 1521949 - 1525569
length: 1207

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3175--100% (1207)biotin carboxylation domain protein
M. thermoresistible (build 8)TH_3286-e-10843.47% (582) PUTATIVE acetyl-/propionyl-coenzyme A carboxylase alpha chain
M. thermoresistible (build 8)TH_3435-e-10547.85% (418) PUTATIVE putative acetyl-/propionyl-coenzyme A carboxylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2529caccA11e-10849.55% (444) acetyl-/propionyl-coenzyme A carboxylase subunit alpha
M. gilvum PYR-GCKMflv_4614-1e-10649.31% (434) carbamoyl-phosphate synthase L chain, ATP-binding
M. tuberculosis H37RvRv2501caccA11e-10849.55% (444) acetyl-/propionyl-coenzyme A carboxylase subunit alpha
M. leprae Br4923MLBr_00726bccA6e-9141.25% (480) acetyl/propionyl CoA carboxylase alpha subunit
M. abscessus ATCC 19977MAB_4093-0.067.32% (667) putative allophanate hydrolase
M. marinum MMMAR_3848accA11e-10649.32% (444) acetyl-/propionyl-coenzyme A carboxylase alpha chain AccA1
M. avium 104MAV_1671-1e-11151.02% (443) acetyl-/propionyl-coenzyme A carboxylase alpha chain
M. smegmatis MC2 155MSMEG_2187-0.068.60% (672) urea amidolyase
M. ulcerans Agy99MUL_3779accA11e-10448.65% (444) acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1
M. vanbaalenii PYR-1Mvan_0345-1e-10950.70% (428) carbamoyl-phosphate synthase L chain, ATP-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      MNRNGEVTVLIANRGEIAVRLIRTARILGLRTVAVFSDADRGAPHVRLAD
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      EAVRIGPAAPRDSYLRTEAILAAAARTGATIVHPGYGFLSEDADFAAAVH
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      QAGLVFAGPTPDQLRVFGTKHTAREMARSAGVPVFAGSDLLADADAAVEA
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      AAVIGYPVMLKATGGGGGIGMRICPDADTVRAAFDQVTAQAERSFGAAGV
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      FVERYVADARHVEVQIFGDGAGRVVSLGDRDCSLQRRNQKVLEEAPAPGI
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      PESIRSRLHRTSRALAAAVGYRSAGTVEFVYDPAREEASFLEVNARLQVE
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      HPVTEAVTGVDLAGWMLRLALGDTSMFDAYPDGAVPVAGHAVEARVYAED
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      PSRDHLPSAGTLTRVRFPTDVRVDTWVDDGTEVTANYDPLLAKVIAAGAD
                                                                                      

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          ------------------------------------------------MP
Mvan_0345|M.vanbaalenii_PYR-1       ----------------------------------------------MTNP
MLBr_00726|M.leprae_Br4923          -------------------------------------------MASHASS
MAB_4093|M.abscessus_ATCC_1997      -------------------------------------------MSNS---
MSMEG_2187|M.smegmatis_MC2_155      -------------------------------------------MTGSDSA
TH_3175|M.thermoresistible__bu      RDDALDRLGAALTGTELHGIETNIGLLGAATVHPEVRAARHTTSTLAGIG
                                                                                      

Mb2529c|M.bovis_AF2122/97           MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDPDVDARHVLEADAAVR
Rv2501c|M.tuberculosis_H37Rv        MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDPDVDARHVLEADAAVR
MMAR_3848|M.marinum_M               MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDADARARHVIEADTAVR
MUL_3779|M.ulcerans_Agy99           MFDTVLVANRGEIAVRVIRTLRRLGIRSVAVYSDADARARHVIEADTAVR
MAV_1671|M.avium_104                MFETVLVANRGEIAVRVIRTLRRLGIRSVAVYSDPDAAARHVLEADEAVR
Mflv_4614|M.gilvum_PYR-GCK          VIKKLLVANRGEIARRVFRTCRELGIATVAVYSDADADAWHVDDADEAVR
Mvan_0345|M.vanbaalenii_PYR-1       TITKLLIANRGEIAARIIRTARAMDVATVALYSDADRDAPYVTLADESVH
MLBr_00726|M.leprae_Br4923          RIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAEAPHVRLADEAFA
MAB_4093|M.abscessus_ATCC_1997      ----TVRVTAPGMLTTVQDWPGRTGYWQVGVPPSGPMDDLSFRLGNRAVG
MSMEG_2187|M.smegmatis_MC2_155      PHVRVAEVLRPGMATTIQDWPGRIGYWQVGVPPSGPMDDVSFRLANIAVG
TH_3175|M.thermoresistible__bu      DPRPRITVERPGLQTTVQDVPGRIGHWQVGVPPSGPMDDLSFRLGNRALG
                                           .    :   :           *.: ..       .  .: :. 

Mb2529c|M.bovis_AF2122/97           LGPAPARESYLDIGKVLDAAARTGAQAIHPGYGFLAENADFAAACERARV
Rv2501c|M.tuberculosis_H37Rv        LGPAPARESYLDIGKVLDAAARTGAQAIHPGYGFLAENADFAAACERARV
MMAR_3848|M.marinum_M               LGPAAARESYLDIGKVIDAAVRTGAQAIHPGYGFLSENAEFAAACDRAGV
MUL_3779|M.ulcerans_Agy99           LGPAAARESYLDIGKVIDAAVRTGAQAIHPGYGFLSENAEFAAACDRAGV
MAV_1671|M.avium_104                LGPAAARDSYLNIDKVVETATRTGAQAIHPGYGFLSENADFAAACERAGV
Mflv_4614|M.gilvum_PYR-GCK          LPGSSPAETYLDGDRVIAAALLTGADAVHPGYGFMSENAGFARACADAGL
Mvan_0345|M.vanbaalenii_PYR-1       LPGTAPADTYLRADLVLAAAARTGADAVHPGYGFLSENADFARACAQAGV
MLBr_00726|M.leprae_Br4923          LGGHTSAESYLDFGKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGL
MAB_4093|M.abscessus_ATCC_1997      NPEGAPGLEATLAGPTLHFTAETLVCVAGAPALVTVNGRPVPQWRAVTVP
MSMEG_2187|M.smegmatis_MC2_155      NPEGAPALEATMGGPALRFDTDTWVCVTGAPAPVSIDGTRVPQWQPVLVQ
TH_3175|M.thermoresistible__bu      NEETAPGLECTASGPALRFSHPTTVCVTGAECLVTVDGAPAPMWEPVEVP
                                        ..       .  :     : . .  .   .  :.   .        

Mb2529c|M.bovis_AF2122/97           VFLGPPARAIEVMGDKIAAKNAVAAFDVPVVPGVARAG---LTDDALVTA
Rv2501c|M.tuberculosis_H37Rv        VFLGPPARAIEVMGDKIAAKNAVAAFDVPVVPGVARAG---LTDDALVTA
MMAR_3848|M.marinum_M               VFLGPPAGAIEVMGDKIAAKNAVSAFDVPVVPGIARPG---LSDDDLIAA
MUL_3779|M.ulcerans_Agy99           VFLGSPAGAIEVMGDKIAAKNAVSAFDVPVVPGIARPG---LTDDDLIAA
MAV_1671|M.avium_104                VFLGPPARAIQVMGDKITAKNAVAEFDVPVVPGVAEPG---LGDDELVAA
Mflv_4614|M.gilvum_PYR-GCK          VFVGPPPDAIDAMGSKLTAKAMMADAGVPVLPGGDATG---LDPDKLRKL
Mvan_0345|M.vanbaalenii_PYR-1       IFVGPSPEAIVAMGSKIAAKDMMRAAGVPVLPGTTVESEEDQDPERLRTA
MLBr_00726|M.leprae_Br4923          IWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPV---KNADEVVAF
MAB_4093|M.abscessus_ATCC_1997      ADGTLAVGAATDTGMRIYVLIAGGIAVPQFLGSAATFTLGGFGGPAGRAL
MSMEG_2187|M.smegmatis_MC2_155      AGQLLDVGMVAGPGLRIYLAVAGGLHADEYLGSAATFTLGGFGGHQGRVL
TH_3175|M.thermoresistible__bu      AGAVLDIGEAA-VGLRTYVLFAGGLDVPAYLGSASTFTLGRFGGHGGRAL
                                                 * :              : .                 

Mb2529c|M.bovis_AF2122/97           AAEVGYPVLIKPSAGGGGKGMRLVQDPARLPEALVSARREAMSSFGDDTL
Rv2501c|M.tuberculosis_H37Rv        AAEVGYPVLIKPSAGGGGKGMRLVQDPARLPEALVSARREAMSSFGDDTL
MMAR_3848|M.marinum_M               ADEVGYPVLVKPSAGGGGKGMRMVEEPARLREALVSARREAASAFGDDTL
MUL_3779|M.ulcerans_Agy99           ADEVGYPVLVKPSAGGGGKGMRMVEEPARLREALVSARREAASAFGDDTL
MAV_1671|M.avium_104                ADEIGYPVLIKPSAGGGGKGMRLVEEPGRLREALVGARREAASSFGDDTL
Mflv_4614|M.gilvum_PYR-GCK          GAEIGYPLLVKASAGGGGRGMRVVESADDLDGAVASASREAMSAFSDGTV
Mvan_0345|M.vanbaalenii_PYR-1       AADIGFPILVKAAFGGGGRGMRIVRGEHELVEAVASARREAASAFGDGTV
MLBr_00726|M.leprae_Br4923          AKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYESAVREATVAFGRGEC
MAB_4093|M.abscessus_ATCC_1997      ATGDVLTLGQSRDGE-----PQCIPGAAQPAIGHHWELAVTEGPHGAPDF
MSMEG_2187|M.smegmatis_MC2_155      GAGDKLEIADNLTGT-----RRRILSDEQPAITSHWNIAVTVGPHSAPEF
TH_3175|M.thermoresistible__bu      VTGDVLRTKPAPSDAGSRPGAGAVPPEVRPALTNSWELAVTEGPHGAPEF
                                                                            :  ...    

Mb2529c|M.bovis_AF2122/97           FLERFVLRPRHIEVQVLADAHGNVVHLGERECSLQRRHQKVIEEAPSPLL
Rv2501c|M.tuberculosis_H37Rv        FLERFVLRPRHIEVQVLADAHGNVVHLGERECSLQRRHQKVIEEAPSPLL
MMAR_3848|M.marinum_M               FLERFVLRPRHIEVQVLADTHGNVVHLGERECSLQRRHQKVIEEAPSPLL
MUL_3779|M.ulcerans_Agy99           FLERFVLRPRHIEVQVLADTHGNVVHLGERECSLQRRHQKVIEEAPSPLL
MAV_1671|M.avium_104                FLERFVLRPRHIEVQILADTHGNVVHLGERECSLQRRHQKVIEEAPSPLL
Mflv_4614|M.gilvum_PYR-GCK          FLERYVQRPRHVEIQLLADMHGTVVSLFERECSVQRRHQKVIEEAPSPVV
Mvan_0345|M.vanbaalenii_PYR-1       FLEKFVESPRHIEVQIFGDSHGTVVHLGERECSIQRRYQKIIEEAPSTAV
MLBr_00726|M.leprae_Br4923          FVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQRRFQKLVEEAPAPFL
MAB_4093|M.abscessus_ATCC_1997      FTRSDIDELLSTHYEVHFNSDRTGVRLIGPKPHWARTDGGEAGLHPSNIH
MSMEG_2187|M.smegmatis_MC2_155      FTPADIDTVLGHDYEVHFNSDRTGVRLIGPKPEWARPDGGEAGLHPSNIH
TH_3175|M.thermoresistible__bu      FTRADIDTLYASRYRVHFNSARTGVRLEGPKPQWARPDGGEAGLHPSNIH
                                    *    :        .:  :   . *     .    *         *:   

Mb2529c|M.bovis_AF2122/97           DPQTRERIGVAACNTARCVDYVGAGTVEFIVSA---QRPDEFFFMEMNTR
Rv2501c|M.tuberculosis_H37Rv        DPQTRERIGVAACNTARCVDYVGAGTVEFIVSA---QRPDEFFFMEMNTR
MMAR_3848|M.marinum_M               DAPTRARIGAAACNTARSVDYVGAGTVEFIVSG---DRPDEFFFMEMNTR
MUL_3779|M.ulcerans_Agy99           DAPTRARIGAAACNTARSVDYVGAGTVELIVSG---DRPDEFFFMEMNTR
MAV_1671|M.avium_104                DPETRARIGAAACNTARSVDYVGAGTVEFIVSA---DRPDEFFFMEMNTR
Mflv_4614|M.gilvum_PYR-GCK          DDDLRARMGAAAVAAAQAVGYVGAGTVEFVLDANGGDDDGTFAFLEMNTR
Mvan_0345|M.vanbaalenii_PYR-1       DERLRDELGRAAVAAGKALSYEGAGTVEFVMAP-----DGSFYFLEVNTR
MLBr_00726|M.leprae_Br4923          TDAQRKEIHESAKRICKEAHYYGAGTVEYLVGQ-----DGLISFLEVNTR
MAB_4093|M.abscessus_ATCC_1997      DNAYSVGTLDFTGDTPILLGPDGPSLGGFVCPVT-VVSADRWKLGQLRAG
MSMEG_2187|M.smegmatis_MC2_155      DNAYSVGSLDFTGDTPILLGPDGPSLGGFVCPVT-VTSADRWKLGQLAPG
TH_3175|M.thermoresistible__bu      DNAYAVGALDFTGDTPILLGPDGPSLGGFVCPVT-VTSADRWKLGQLRPG
                                               :          *..    :         .   : :: . 

Mb2529c|M.bovis_AF2122/97           LQVEHPVTEAITGLDLVEWQLRVGAGEKLGFAQNDIELRGHAIEARVYAE
Rv2501c|M.tuberculosis_H37Rv        LQVEHPVTEAITGLDLVEWQLRVGAGEKLGFAQNDIELRGHAIEARVYAE
MMAR_3848|M.marinum_M               LQVEHPVTEAVTGLDLVEWQLRVAAGEKLGFAQDDIELNGHAIEARVYAE
MUL_3779|M.ulcerans_Agy99           LQVEHPVTEAVTGLDLVEWQLRVAAGEKLGFAQDDIELNGHAIEARVYAE
MAV_1671|M.avium_104                LQVEHPVTEAVTGLDLVEWQLRVAAGEKLVFAQDDIELRGHAIEARVYAE
Mflv_4614|M.gilvum_PYR-GCK          LQVEHPVTELVTGLDLVRLQLLVAMGRPLPAEVSKPRITGHAVEARLYAE
Mvan_0345|M.vanbaalenii_PYR-1       LQVEHPVTELVTGIDLVRAQLLVAAGHPIPSEMLHATPRGHAVEVRLYAE
MLBr_00726|M.leprae_Br4923          LQVEHPVTEETTGIDLVLQQFKIANGEKLELIK-DPIPCGHAIEFRINGE
MAB_4093|M.abscessus_ATCC_1997      DTVRFIRIEASRSASLRSIGIDRRGHWPSVFSTRGDGDDG-VLAYRPARD
MSMEG_2187|M.smegmatis_MC2_155      ATVRFVAVREAAAAPADTVTRARRAYLPAVFSTGGDTDNG-ILGHTTSSD
TH_3175|M.thermoresistible__bu      DTVRFVPVRAAHTPSRRELGLSRAAATPVLARTGGDGDDG-VLAR---RD
                                      *..   .                              *  :      :

Mb2529c|M.bovis_AF2122/97           DPAREFLPTGGRVLAVFEPAGPGVRVDSSLLGGTVVGSDYDPLLTKVIAH
Rv2501c|M.tuberculosis_H37Rv        DPAREFLPTGGRVLAVFEPAGPGVRVDSSLLGGTVVGSDYDPLLTKVIAH
MMAR_3848|M.marinum_M               DPARGFLPTGGRVLQVAEPSGTGIRVDSSLLADTVVGSDYDPMLSKVIAH
MUL_3779|M.ulcerans_Agy99           DPARGFLPTGGRVLQVAEPSGTGIRVDSSLLADTVVGSDYDPMVSKVIAH
MAV_1671|M.avium_104                DPARGFLPTGGRVLGVFEPSGDGVRVDSSLLPGTVVGSDYDPMLSKVIAH
Mflv_4614|M.gilvum_PYR-GCK          DPTKGYLPQTGTLRTMQIPDHVGVRVDSGVRDGSVVSHHYDAMLAKVIAW
Mvan_0345|M.vanbaalenii_PYR-1       DVAAGFVPVSGTLTTLEFPTFDGIRIDAGFTSGSKVSTFYDPMLAKVIGF
MLBr_00726|M.leprae_Br4923          DAGRNFLPSPGPVSKFHPPTGPGVRLDSGVETGSVIGGQFDSMLAKLIVH
MAB_4093|M.abscessus_ATCC_1997      DAPEMTYRRSGDDNILVEYGDLTLDLALRARVHALHQRLEDTHTTGIIDL
MSMEG_2187|M.smegmatis_MC2_155      GTVDVTYRRTGDDNVLVEYGEMRLDLALRARVHALHHALENHRPDGLIDL
TH_3175|M.thermoresistible__bu      GDPPVTYRRSGDDNVLVEYGDIVLDLALRARVHALHTRLDGSAP-GIVDL
                                    .         *    .       : :       :      .     ::  

Mb2529c|M.bovis_AF2122/97           G-ADREEALDRLDQALARTAVLGVQTNVEFLRFLLADERVRVGDLDTAVL
Rv2501c|M.tuberculosis_H37Rv        G-ADREEALDRLDQALARTAVLGVQTNVEFLRFLLADERVRVGDLDTAVL
MMAR_3848|M.marinum_M               G-ANREQALERLDRALAHTAILGVQTNVEFLRFLLADERVRAGDLDTALL
MUL_3779|M.ulcerans_Agy99           G-ANREQALERLDRALAHTAILGVQTNVEFLRFLLADERVRAGDLDTALL
MAV_1671|M.avium_104                G-ADRDEALARLDRALSHTAILGVQTNVEFLRFLLADERVRAGDLDTALL
Mflv_4614|M.gilvum_PYR-GCK          A-PTRAEALGALSAALAGARIHGLTTNRDLLVRVLRHDEFAGRGTDTGFL
Mvan_0345|M.vanbaalenii_PYR-1       G-ATRADACALVARALTETRVHGVTTNRDLLVGILREQEFLAGAIDTGYL
MLBr_00726|M.leprae_Br4923          G-ATRQEALARARRALDEFEVEGLATVIPFHRAVVSDPALIG--------
MAB_4093|M.abscessus_ATCC_1997      TPGIRSLQVHFDPDRLPMGKVLGLLDDIDEHLPASEELVVPSRRVAMPLS
MSMEG_2187|M.smegmatis_MC2_155      TPGVRSLQVKVDPVRLPVSALVPLLTEIEASLPAAQELVVPSRTVRLPLS
TH_3175|M.thermoresistible__bu      TPGIRSLQVHVDPDVLPIPRLLDLLCEIEDDLPATADLVVPSRLVRLPLS
                                        *          *    :  :            .  .          

Mb2529c|M.bovis_AF2122/97           D--ERSADFTARPAPDDVLAAGGLYRQWALARRA---QGDLWAAPSGWRG
Rv2501c|M.tuberculosis_H37Rv        D--ERSADFTARPAPDDVLAAGGLYRQWALARRA---QGDLWAAPSGWRG
MMAR_3848|M.marinum_M               D--ERLADFVPLAAPDDVFAAAGLYVQQALSRRA---AGSLWAAPSGWRV
MUL_3779|M.ulcerans_Agy99           D--ERLADFVPLAAPDDVFAAAGLYVQQALSRRA---AGSLWAAPSGWRV
MAV_1671|M.avium_104                D--ARLADFTPLPAPDDVLAAAGLYRQSALAARARRFAGNPWAAPTGWRA
Mflv_4614|M.gilvum_PYR-GCK          DR-HDVADLGAALIDRDGEGLHAIAATLAQVAGRRAAAPVQPTLPAGWRN
Mvan_0345|M.vanbaalenii_PYR-1       ER-HDPAELTGASSSVSTLRTHALAAALAAQAGRRTDTSILPGLPSGWRT
MLBr_00726|M.leprae_Br4923          -------------------------------------DNNSFSVHTRWIE
MAB_4093|M.abscessus_ATCC_1997      WDDPSAREAMERYRLGVRADAPWMPWNIEFIRRINGLDSVDEVHRTVYDA
MSMEG_2187|M.smegmatis_MC2_155      WDDPATREAIERYMHGVRADAPWCPWNIEFIRRMNGLASVDDVHRIVYDA
TH_3175|M.thermoresistible__bu      WDDPATREAIARYMSGVRADAPWCPSNIEFIRRVNGLDSVEEVRDIVFRA
                                                                                   :  

Mb2529c|M.bovis_AF2122/97           GGHMAPVRTAMRTPLRSETVSVWGPPESAQVQVG-DGEIDCASVQVTREQ
Rv2501c|M.tuberculosis_H37Rv        GGHMAPVRTAMRTPLRSETVSVWGPPESAQVQVG-DGEIDCASVQVTREQ
MMAR_3848|M.marinum_M               GGVTAPVRTAMQTPLRTETVSVFGLPEGAHVQVG-DGEMLSASVQLAPGV
MUL_3779|M.ulcerans_Agy99           GGVTAPVRTAMQTPLRTETVSVFGLPEGAHVQVG-DGEMLLASVQLAPGV
MAV_1671|M.avium_104                GGSPAPVRTDMRTALRTETVSVWGPPEAAEVQVG-AGERLAASAHLGPDR
Mflv_4614|M.gilvum_PYR-GCK          NPSQLQSTGWLTADGRERRVGYALLRDGVEVEVDGKPVEDVSVLVQRPDR
Mvan_0345|M.vanbaalenii_PYR-1       LRSQDQVVAFTAGD-HTVEVRYRFGRATVSVRIG-DWEPEVQIVAASASC
MLBr_00726|M.leprae_Br4923          TEWNNTIEPFIDNQPLDEED--TRPQQTVIVEVD----GRRLEVSLPADL
MAB_4093|M.abscessus_ATCC_1997      SYLVLGLGDVYLGAPVATPVDPRHRLVTTKYNPARTWTPENAVGIGGAYL
MSMEG_2187|M.smegmatis_MC2_155      EYLVLGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTPENAVGIGGAYL
TH_3175|M.thermoresistible__bu      EYLTLGLGDVYLGAPVATPLDPRHRLVTTKYNPARTWTAENSVGIGGAYL
                                                                .  .                  

Mb2529c|M.bovis_AF2122/97           MSVTISGLRRDYRWAEADRHLWIADERGTWHLREAEEHKI-HRAVGARPA
Rv2501c|M.tuberculosis_H37Rv        MSVTISGLRRDYRWAEADRHLWIADERGTWHLREAEEHKI-HRAVGARPA
MMAR_3848|M.marinum_M               MSVTVDGLRRDYRWAEAERHLWIADVRGTWHIREAEEHKI-HRAAGERPA
MUL_3779|M.ulcerans_Agy99           MSVTVDGLRRDYRWAEAERHLWIADVRGTWHIREAEEHKI-HRAAGERPA
MAV_1671|M.avium_104                ISVTLDGRRRDYRWAEADRHLWIADERGTWHLREAEQTTI-HRAAGPQRA
Mflv_4614|M.gilvum_PYR-GCK          VVLETGGVRRGYDVVLDADIAYVDSPAGSTAFTQVPRFLD-PSALKP-AG
Mvan_0345|M.vanbaalenii_PYR-1       LDAVIDGVRRQYHLTISGATHYVDSGLGSSALTEVDRFPD-PSANQE-PG
MLBr_00726|M.leprae_Br4923          ALANPAG----------------CNPAGVIRKKPKPRKRGGHTGAATSGD
MAB_4093|M.abscessus_ATCC_1997      CIYGMEGPGGYQLVGRTVQVWNHQHPDNAGAFEPGTPWLLRFFDQINWYP
MSMEG_2187|M.smegmatis_MC2_155      CIYGMEGPGGYQFVGRTTQIWNHRHPLPAHGFEPEHPWLLRFFDRISWYP
TH_3175|M.thermoresistible__bu      CIYGMEGPGGYQFVGRTTQVWSSHR--HRGPFDSEHPWLLRFFDRITWYP
                                          *                                           

Mb2529c|M.bovis_AF2122/97           EVVSPMPGSVIAVQVESG---SQISAGDVVVVVEAMKMEHSLEAPVSGRV
Rv2501c|M.tuberculosis_H37Rv        EVVSPMPGSVIAVQVESG---SQISAGDVVVVVEAMKMEHSLEAPVSGRV
MMAR_3848|M.marinum_M               EVVSPMPGNVIAVQAESG---TAVSEGDVVVIIEAMKMEHPLVAPISGRV
MUL_3779|M.ulcerans_Agy99           EVVSPMPGNVIAVRAESG---TAVSEGDVVVIIEAMKMEHPLVAPISGRV
MAV_1671|M.avium_104                EILSPMPGSVIAVQTPSG---SDVSEGDVVVVVEAMKMEHSLAAPVSGRV
Mflv_4614|M.gilvum_PYR-GCK          SLTAPMPGSVIRLPVAAG---DVVTAGQALVVVEAMKMEHTIVSPIDGIV
Mvan_0345|M.vanbaalenii_PYR-1       SLLAPMPGSVVRVEVDEG---AEVAAGTTIVVLEAMKMEHSVRAPAGGVV
MLBr_00726|M.leprae_Br4923          AVTAPMQGTVVKVAVAEG---QTVMTGDLVVVLEAMKMENPVTAHKDGII
MAB_4093|M.abscessus_ATCC_1997      VSGEELLELRDELATGRGNGGITITEGEFSMAGYSAFLAHNAASIGQFRD
MSMEG_2187|M.smegmatis_MC2_155      VSAEELLDLRADMAAGRG--HVDITDGVFALAEHDAFLAENADDIAATRA
TH_3175|M.thermoresistible__bu      VSAEELLDLRADIAAGRG--AVDIAEGTFSLAEHQRFLSDNAESIAAFRA
                                         :      : .  *     :  *   :      : .          

Mb2529c|M.bovis_AF2122/97           QVL-VSVGDQVKVEQVLARIKD----------------------------
Rv2501c|M.tuberculosis_H37Rv        QVL-VSVGDQVKVEQVLARIKD----------------------------
MMAR_3848|M.marinum_M               EVL-VAVGDQVKVEQVLARLIPDTEQAQSKDSAESKD-------------
MUL_3779|M.ulcerans_Agy99           EVL-VAVGDQVKVEQVLARLIPDTEQAQSKDSAESKD-------------
MAV_1671|M.avium_104                EVL-VCVGDQVSVDQVLARVVPEESDPPADSSKDET--------------
Mflv_4614|M.gilvum_PYR-GCK          AELSVEVGQQVSTGDALAVVGAAAGADQD---------------------
Mvan_0345|M.vanbaalenii_PYR-1       ASLSVAVGTQVESGQVLAVVAEAQP-------------------------
MLBr_00726|M.leprae_Br4923          TGLAVEAGTAITQGTVLAEIK-----------------------------
MAB_4093|M.abscessus_ATCC_1997      HQRLAYAAEREAWSTAGEFARA----------------------------
MSMEG_2187|M.smegmatis_MC2_155      TMEAARAEERQRWSDAGEFARKESA-------------------------
TH_3175|M.thermoresistible__bu      RQTAAFAAERAAWEAAGEFDRAERAASAVSAGAAEELMLADGEQRVDAPF
                                        . .        .                                  

Mb2529c|M.bovis_AF2122/97           --------------------------------------------------
Rv2501c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_3848|M.marinum_M               --------------------------------------------------
MUL_3779|M.ulcerans_Agy99           --------------------------------------------------
MAV_1671|M.avium_104                --------------------------------------------------
Mflv_4614|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0345|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00726|M.leprae_Br4923          --------------------------------------------------
MAB_4093|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_2187|M.smegmatis_MC2_155      --------------------------------------------------
TH_3175|M.thermoresistible__bu      SSSVWRIDVTEGQSVQAGQPLLALEAMKMETVLRAPVDGLVCKVLVSAGH
                                                                                      

Mb2529c|M.bovis_AF2122/97           -----------------
Rv2501c|M.tuberculosis_H37Rv        -----------------
MMAR_3848|M.marinum_M               -----------------
MUL_3779|M.ulcerans_Agy99           -----------------
MAV_1671|M.avium_104                -----------------
Mflv_4614|M.gilvum_PYR-GCK          -----------------
Mvan_0345|M.vanbaalenii_PYR-1       -----------------
MLBr_00726|M.leprae_Br4923          -----------------
MAB_4093|M.abscessus_ATCC_1997      -----------------
MSMEG_2187|M.smegmatis_MC2_155      -----------------
TH_3175|M.thermoresistible__bu      TVDGGDPLVVVRPGGER