For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2305 (pta)

annotation: PROBABLE PHOSPHATE ACETYLTRANSFERASE PTA (PHOSPHOTRANSACETYLASE)
coordinates: 4522026 - 4524134
length: 703

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2305pta-100% (703)PROBABLE PHOSPHATE ACETYLTRANSFERASE PTA (PHOSPHOTRANSACETYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0416pta0.075.36% (686) phosphate acetyltransferase
M. gilvum PYR-GCKMflv_0205-0.080.41% (689) phosphate acetyltransferase
M. tuberculosis H37RvRv0408pta0.075.22% (686) phosphate acetyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4226c-0.074.46% (689) phosphate acetyltransferase
M. marinum MMMAR_0710pta0.075.80% (686) phosphate acetyltransferase Pta
M. avium 104MAV_4760-0.074.64% (690) phosphate acetyltransferase
M. smegmatis MC2 155MSMEG_0783pta0.082.27% (688) phosphate acetyltransferase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0700-0.079.59% (686) phosphate acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


TH_2305|M.thermoresistible__bu      ------MSAASEAPSPEP-SISAIYIAAPEGDTGKSTIALGILHRLAANV
MSMEG_0783|M.smegmatis_MC2_155      ------------MPEGE--AATAIYIASPEGDTGKSTIALGILHRLAATV
Mflv_0205|M.gilvum_PYR-GCK          MRAGAQFGRLWDVPDAAKTTISAIYVASPEGDTGKSTIALGILHRLAATV
Mvan_0700|M.vanbaalenii_PYR-1       ------------MPDATTGTTSSIYLASPEGDTGKSTIALGILHRLSATA
MAB_4226c|M.abscessus_ATCC_199      ---------------MTQPKASSIYIASPEGDTGKSTVALGVMHRLAASV
Mb0416|M.bovis_AF2122/97            --------------MADSS---AIYLAAPESQTGKSTIALGLLHRLTAMV
Rv0408|M.tuberculosis_H37Rv         --------------MADSS---AIYLAAPESQTGKSTIALGLLHRLTAMV
MMAR_0710|M.marinum_M               --------------MSTGSGATGIYIAAPEPESGKSTIALGILHRLAATV
MAV_4760|M.avium_104                --------------MADIS---AIYVAAPEPETGKSTVALGLLHRLTATV
                                                          .**:*:** ::****:***::***:* .

TH_2305|M.thermoresistible__bu      ARVGVFRPITR-LNEDRDYILELLLAHATADLSYEDCVGVGYQQLHEDTD
MSMEG_0783|M.smegmatis_MC2_155      PKVGVFRPITR-LGEDRDYILELLLAGTTAGLPYEDCVGVSYQQVHEDPD
Mflv_0205|M.gilvum_PYR-GCK          ARVGVFRPITRGDGAPRDYILELLLDQTTADLPYEDCVGVTYHQLHEDPE
Mvan_0700|M.vanbaalenii_PYR-1       ARVGVFRPITR-MGESRDYILELLLDHTTAGLPYEDCVGVGYQQLHDDPD
MAB_4226c|M.abscessus_ATCC_199      ARVGVFRPIAR-SGESVDYILELLLEQSTADIAYEDCLGVSYHDVHQDPD
Mb0416|M.bovis_AF2122/97            AKVGVFRPITR-LSAERDYILELLLAHTSAGLPYERCVGVTYQQLHADRD
Rv0408|M.tuberculosis_H37Rv         AKVGVFRPITR-LSAERDYILELLLAHTSAGLPYERCVGVTYQQLHADRD
MMAR_0710|M.marinum_M               AKVGVFRPITR-RGERRDYILELLLEQTTAGLSYEQCVGVTYQQLHDDLE
MAV_4760|M.avium_104                AKVGVFRPITR-DGQDRDYILELLLSRTTAGLSYQQCVGVTYQQLHADGD
                                    .:*******:*  .   ********  ::*.:.*: *:** *:::* * :

TH_2305|M.thermoresistible__bu      GAIAEIVDRYHRMAAACDAVLIVGSDYTDI---ATPTELSVNARIAVNLG
MSMEG_0783|M.smegmatis_MC2_155      AAIAEIVDRYHRVADQCDAVLIVGSDYTDI---ATPSELSMNARIAVNLG
Mflv_0205|M.gilvum_PYR-GCK          AALAEIVDRFHAVADRCDAVLVVGSDYTDV---AAPSELSVNARIAANLG
Mvan_0700|M.vanbaalenii_PYR-1       AALAEIVDRFHRVADRCDAVLVVGSDYTDV---AAPSELSVNARIAANLG
MAB_4226c|M.abscessus_ATCC_199      AAIAQIVDRYHAVAERCDAVVIVGSDYTDV---ASPSELGTNARIAVNLG
Mb0416|M.bovis_AF2122/97            DAIAEIVDSYHAMADECDAVVVVGSDYTDV---TSPTELSVNARIAVNLG
Rv0408|M.tuberculosis_H37Rv         DAIAEIVDSYHAMADECDAVVVVGSDYTDV---TSPTELSVNGRIAVNLG
MMAR_0710|M.marinum_M               AAIADIVAAYHAMADACDAVVIVGSDYTDV---TTPTELSVNARIAVNLG
MAV_4760|M.avium_104                AAIATIVDAYHAMAELCDVVVIVGSDYSELGQAIRPAELSTNARIAVNLG
                                     *:* **  :* :*  **.*::*****:::     *:**. *.***.***

TH_2305|M.thermoresistible__bu      APVLLAVRAQDRTPEQIAQVVEVCTAELAAQHAHTAAVVANRCDPAQLDA
MSMEG_0783|M.smegmatis_MC2_155      APVVLAVKAADRTPDEVVHVVEVCLAELAGQHAHTSAVVANRCDPAQLTA
Mflv_0205|M.gilvum_PYR-GCK          APVVLAVKAKGRNPEQVAQVVELCVDEIAAQHAHTAAVVANRCDPAQLVE
Mvan_0700|M.vanbaalenii_PYR-1       APVVLAVKGKGRTPEQILQVVDVCINEIAAQHAHTAAVVVNRCDPILLVD
MAB_4226c|M.abscessus_ATCC_199      APVLLTIKGFDRTPDEVAALAEVCLGELKAQRAHTAAIVANRCNPGQLDE
Mb0416|M.bovis_AF2122/97            APVLLTVRAKDRTPDQVASVVEVCLAELDTQRAHTAAVVANRCELSAIPA
Rv0408|M.tuberculosis_H37Rv         APVLLTVRAKDRTPDQVASVVEVCLAELDTQRAHTAAVVANRCELSAIPA
MMAR_0710|M.marinum_M               APVLLAVSAKGRDADQVSGVVAVCLAELAAQHAHTAAVVANRCEPAQLAA
MAV_4760|M.avium_104                APILLTVSGKGRTAAEVATVVQVCLAELDAQHAHTAAVVANRCEPAELDA
                                    **::*:: . .* . ::  :. :*  *:  *:***:*:*.***:   :  

TH_2305|M.thermoresistible__bu      VRTALTELLPNGPKCFVLPEEPLLVAPSVAELQRAVDGTLIQGDPAMLHR
MSMEG_0783|M.smegmatis_MC2_155      VSEALR---PLGPPAYVLPEEPLLVAPSVAELQKAVDGTVVAGDPALLSR
Mflv_0205|M.gilvum_PYR-GCK          VGEALT---KIEPQSYVLPEEPLLVAPSVAELQAAVEGAVVQGDPALLHR
Mvan_0700|M.vanbaalenii_PYR-1       VAEALA---SIGPQSYVLPEEPLLVAPSVSELRSAVEGHQVQGDPALLDR
MAB_4226c|M.abscessus_ATCC_199      VRQALA---RFDKPAWVLPEVPLLVSPSVEELMKAVKGSLVSGDEALLSR
Mb0416|M.bovis_AF2122/97            VTDALR---RFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALRER
Rv0408|M.tuberculosis_H37Rv         VTDALR---RFTPPSYVVPEEPLLSAPTVAELTQAVNGAVVSGDVALRER
MMAR_0710|M.marinum_M               VGDALR---AFAPPSYVLPEEQLLSAPTVSELEKSVNGTPISGDASLWGR
MAV_4760|M.avium_104                VAEALR---GFPQRCYVLPDEPLLSAPTVTELEKAVAGSPVSGEESLRER
                                    *  **         .:*:*:  ** :*:* **  :* *  : *: ::  *

TH_2305|M.thermoresistible__bu      EVMDVLVAGMTAEHVLERLTEGVAVITPGDRSDVVLAMVSAHAAEGFPSL
MSMEG_0783|M.smegmatis_MC2_155      EALGVLVAGMTAEHVLERLTEGVAVVTPGDRSDVVLAVVSAHAAEGFPSL
Mflv_0205|M.gilvum_PYR-GCK          EVLDVLVAGMTAEHVLERLTEGGVVITPGDRSDVVLAVLSAHAAEGFPSL
Mvan_0700|M.vanbaalenii_PYR-1       EVLDVLVAGMTAEHVLERLTEGVAVVTPGDRSDVVLAVLSAHAAAGFPSL
MAB_4226c|M.abscessus_ATCC_199      EATSFMVAGMTAEHCLERLKEGQAVIFPADRSDVLLAVASAHVAEGFPSL
Mb0416|M.bovis_AF2122/97            EVMGVLAAGMTADHVLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSL
Rv0408|M.tuberculosis_H37Rv         EVMGVLAAGMTADHVLERLTDGMAVITPGDRSDVVLAVASAHAAEGFPSL
MMAR_0710|M.marinum_M               EVTSLLVAGMTADHVLERLRDGMAVITPGDRSDVVLAVASAHAAEGFPSL
MAV_4760|M.avium_104                EVTGILVAGMTADHVLERLADGMAVITPGDRSDVVLAVASAHAAEGFPSL
                                    *. ..:.*****:* **** :* .*: *.*****:**: ***.* *****

TH_2305|M.thermoresistible__bu      SALILNGGWELHPSIAALVSGLGLSLPMIATDLGTFATASRVAATRGRVT
MSMEG_0783|M.smegmatis_MC2_155      STIILNGGLDLHPAIAKLVDGLGLKLPIIATPYGTFETASRVASARGRVT
Mflv_0205|M.gilvum_PYR-GCK          SGVILNGGLPLHPAIDGLVAGLGQRLPIVETRFGTFETASRVAATRGRVT
Mvan_0700|M.vanbaalenii_PYR-1       SAVILNGGLTLHPAIGSLVAGLGLRLPVIETRLGTFETASRIAATRGRVT
MAB_4226c|M.abscessus_ATCC_199      SAIILNGGLKLHPRIADLVDGIGLRLPIIETDSGTFETASAAAHARGRVT
Mb0416|M.bovis_AF2122/97            SCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAASARGLVT
Rv0408|M.tuberculosis_H37Rv         SCIVLNGGFQLHPAIAALVSGLRLRLPVIATALGTYDTASAAASARGLVT
MMAR_0710|M.marinum_M               SCIVLNGGFELHPSIASLVAGLRLRLPIIGTDLGTFDTASAAATARGRVK
MAV_4760|M.avium_104                SCIVLNGGFALHPSIAALVAGLRLRLPIVATALGTYDTASAAAAARGRVT
                                    * ::****  *** *  ** *:   **:: *  **: ***  * :** *.

TH_2305|M.thermoresistible__bu      AASHRKIDTALQLMETYVDTSDMLEQLAIPIPTVVTPQMFTYRLLERARA
MSMEG_0783|M.smegmatis_MC2_155      STSQRKIDTALQIMERHVDIDDLLARLRLPIPEVTTPQMFTYQLLDRARA
Mflv_0205|M.gilvum_PYR-GCK          SQSHRKIDTALTLMDTYVDTAELLAHLALPIPSVVTPQMFTHQLLERASA
Mvan_0700|M.vanbaalenii_PYR-1       SKSHRKIDTALTLMDTYVDTAELLAHLAIPIPTVVTPQMFTHQLIEQARS
MAB_4226c|M.abscessus_ATCC_199      VASARKIDTALALMDRYVDGADLVAQLAIPIPSVTTPQMFEYQLLDRARD
Mb0416|M.bovis_AF2122/97            ATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARS
Rv0408|M.tuberculosis_H37Rv         ATSQRKIDTALELMDRHVDVAGLLAQLTIPIPTVTTPQMFTYRLLQQARS
MMAR_0710|M.marinum_M               ATSQRKIDTALGLMDRYVDIEDLLAKLAIPIPTVTTPQMFMYRVQQQARS
MAV_4760|M.avium_104                ATSQRKIDTALELMDRHVDIADLLEQLAIPIPTVTTPQMFIHQLTLQARA
                                      * ******* :*: :**   :: :* :*** *.***** :::  :*  

TH_2305|M.thermoresistible__bu      DRKHIVLPEGEDDRILISAGRLLQRGVADLTILGDEAQVRGRAAELGVDL
MSMEG_0783|M.smegmatis_MC2_155      DRKRIVLPEGDDDRILKAAGRLLRRGVADLTILGEENQIRSRGAELGVDL
Mflv_0205|M.gilvum_PYR-GCK          DRQRIVLPEGNDDRILRAAGRLLQRSVADLTILGDESQVRARAAELGVDL
Mvan_0700|M.vanbaalenii_PYR-1       DRKRIVLPEGNDDRILKAAGRLLHRGVADLTILGEEAQVRARAAELGLDL
MAB_4226c|M.abscessus_ATCC_199      NRKRIVLPEGDDDRILKAAGRLLQRQVADLTILGEEAEIRSRAAELGVDI
Mb0416|M.bovis_AF2122/97            DLMRIVLPEGDDDRILKSAGRLLQRGIVDLTILGDEAKVRLRAAELGVDL
Rv0408|M.tuberculosis_H37Rv         DLMRIVLPEGDDDRILKSAGRLLQRGIVDLTILGDEAKVRLRAAELGVDL
MMAR_0710|M.marinum_M               DRQRIVLPEGEDDRILKSAGRLLQRNVADLTILGDEAEIRLRAAELGVSL
MAV_4760|M.avium_104                DRKHIVLPEGDDDRILRAAGRVLQRRVADLTILGDEARIRQRSGELGVDL
                                    :  :******:***** :***:*:* :.******:* .:* *..***:.:

TH_2305|M.thermoresistible__bu      SGATVIDPRTSDLRERFAEQYAEMREHKGVTLEQAREIMLDVSYFGTMLV
MSMEG_0783|M.smegmatis_MC2_155      SAATVLDPRTSDLCEAFAQQYAELRKHKGITLDQAREIIVDVSYFGTMLV
Mflv_0205|M.gilvum_PYR-GCK          SHAAVLDPKTSELCDRFAEQYAELRQHKGVTLDRAREVIHDVSYFGTMLV
Mvan_0700|M.vanbaalenii_PYR-1       STAVVLDPQTSELCDRFAEQYAKLRAHKGVTVEQAHEIIHDVSYFGTMLV
MAB_4226c|M.abscessus_ATCC_199      SNALVVSPKTSDLAEKFADQYFELRKHKGMTPDRAREIMRNVSYFGTMLV
Mb0416|M.bovis_AF2122/97            DGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLV
Rv0408|M.tuberculosis_H37Rv         DGATVIEPCASELHDQFADQYAQLRKAKGITVEHAREIMNDATYFGTMLV
MMAR_0710|M.marinum_M               DSATVIDPRTSSLCNEFADQYAQLRKAKGITHEQAREIMNDATYFGTMLV
MAV_4760|M.avium_104                SDVKVIDPRTSALRPEFAQQYAQLRKAKGVTIEQAREIMRDATYFGTMLV
                                    . . *:.* :* *   **:** ::*  **:* ::*:*:: :.:*******

TH_2305|M.thermoresistible__bu      YNDMVDGMVSGAAHTTAHTVRPAFEIIRTQPDVSTVSSIFLMCLSDRVLA
MSMEG_0783|M.smegmatis_MC2_155      HNDMVDGMVSGAAHTTAHTVRPAFEIIKTLPDVSTVSSIFLMCLEDRVLA
Mflv_0205|M.gilvum_PYR-GCK          HNDMVDGMVSGARHTTAHTIRPAFEIIRTAPGVSTVSSIFLMCLADEVLA
Mvan_0700|M.vanbaalenii_PYR-1       HNDLVDGMVSGACHTTAHTIRPALEIIRTAPGVSTVSSIFLMCLAHEVLA
MAB_4226c|M.abscessus_ATCC_199      YNDIVDGMVSGAAHTTAHTIRPAFEVIRTTSGVSTVSSIFLMCLADRVLA
Mb0416|M.bovis_AF2122/97            HNCHADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLA
Rv0408|M.tuberculosis_H37Rv         HNCHADGMVSGAAHTTAHTVRPALEIIKTVPGISTVSSIFLMCLPDRVLA
MMAR_0710|M.marinum_M               YNGMADGMVSGAAHTTAHTVRPALQIIRTVPGVSTVSSIFLMCLPDRVLA
MAV_4760|M.avium_104                YTSQVDGMVSGAAHTTAHTVRPAFEIIKTVPDVSTVSSIFLMCLPDRVLA
                                    :.  .******* ******:***:::*:* ..:*********** ..***

TH_2305|M.thermoresistible__bu      YGDCAIVPDPTAEQLADIAISSARTAARFDIEPRVAMLSYSTGTSGAGAD
MSMEG_0783|M.smegmatis_MC2_155      YGDCAIVPDPTAEQLADIAISSARTAAQFGIEPRVAMLSYSTGTSGTGAD
Mflv_0205|M.gilvum_PYR-GCK          YGDCAIVPDPTAEQLADIAISSARTAAQFGIEPRVAMLSYSTGTSGTGAD
Mvan_0700|M.vanbaalenii_PYR-1       YGDCAIVPDPTAEQLADIAISSARTAAQFGIEPKVAMLSYSTGTSGTGAD
MAB_4226c|M.abscessus_ATCC_199      YGDCAIVPDPTSEQLADIAISSARTAAQFGIDPRVAMLSYSTGSSGSGAD
Mb0416|M.bovis_AF2122/97            YGDCAIIPNPTVEQLADIAICSARTAAQFGIEPRVAMLSYSTGDSGKGAD
Rv0408|M.tuberculosis_H37Rv         YGDCAIIPNPTVEQLADIAICSARTAAQFGIEPRVAMLSYSTGDSGKGAD
MMAR_0710|M.marinum_M               YGDCAIIPNPTVEELADIAVCSARTAAQFGVEPRVAMLSYSTGASGSGAD
MAV_4760|M.avium_104                YGDCAIIPNPTPEQLADIAISSARTAAQFGIEPRVAMLSYSTGDSGTGAD
                                    ******:*:** *:*****:.******:*.::*:********* ** ***

TH_2305|M.thermoresistible__bu      VEKVKRATELVRQRQPDLLVEGPIQYDAAVEPSVARTKMPDSPVAGRATV
MSMEG_0783|M.smegmatis_MC2_155      VEKVKAATDLVRERDKTLLVEGPIQYDAAVEPSVAKTKMPDSEVAGRATV
Mflv_0205|M.gilvum_PYR-GCK          VDKVRQATELVRSREPDLPVEGPIQYDAAVEPSVAQTKMPDSAVAGRATV
Mvan_0700|M.vanbaalenii_PYR-1       VDKVRKATELVRSRAPELLVEGPIQYDAAVEPSVAMTKMPDSRVAGHATV
MAB_4226c|M.abscessus_ATCC_199      VEKVRIATELVRSRQPELLVEGPIQYDAAVEPSVAATKMPDSPVAGRATV
Mb0416|M.bovis_AF2122/97            VDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRATV
Rv0408|M.tuberculosis_H37Rv         VDKVRAATELVRAREPQLPVEGPIQYDAAVEPSVAATKLRDSPVAGRATV
MMAR_0710|M.marinum_M               VDKVRAATELVRERDPQLMVEGPIQYDAAVDLSVAATKMRDSAVAGRATV
MAV_4760|M.avium_104                VEKVRTATQLVRQRNPDLPVEGPIQYDAAIEPSVAATKLRDSPVAGRATV
                                    *:**: **:*** *   * **********:: *** **: ** ***:***

TH_2305|M.thermoresistible__bu      LIFPDLNTGNNTYKAVQRSAGAVAIGPVLQGLNKPVNDLSRGALIEDIVN
MSMEG_0783|M.smegmatis_MC2_155      LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVN
Mflv_0205|M.gilvum_PYR-GCK          LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVN
Mvan_0700|M.vanbaalenii_PYR-1       LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLNKPVNDLSRGALVEDIVN
MAB_4226c|M.abscessus_ATCC_199      LIFPDLNTGNNTYKAVQRSAGAVAIGPVLQGLRKPINDLSRGALVEDIVN
Mb0416|M.bovis_AF2122/97            LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVN
Rv0408|M.tuberculosis_H37Rv         LIFPDLNTGNNTYKAVQRSAGAIAIGPVLQGLRKPVNDLSRGALVDDIVN
MMAR_0710|M.marinum_M               LIFPDLNTGNNTYKAVQRSAGAVAIGPVLQGLRKPVNDLSRGALVEDIVN
MAV_4760|M.avium_104                LIFPDLNTGNNTYKAVQRSAGALAIGPVLQGLRKPVNDLSRGALVEDIVN
                                    **********************:*********.**:********::****

TH_2305|M.thermoresistible__bu      TVAITAIQAQGGS---
MSMEG_0783|M.smegmatis_MC2_155      TVAITAIQAQGRS---
Mflv_0205|M.gilvum_PYR-GCK          TVAITAIQAQGVH---
Mvan_0700|M.vanbaalenii_PYR-1       TVAITAIQAQG-----
MAB_4226c|M.abscessus_ATCC_199      TVAITAIQAQERKQS-
Mb0416|M.bovis_AF2122/97            TVAITAIQAQGVHE--
Rv0408|M.tuberculosis_H37Rv         TVAITAIQAQGVHE--
MMAR_0710|M.marinum_M               TVAITAIQAQGVHER-
MAV_4760|M.avium_104                TIAITAIQAQGLPGGR
                                    *:********