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M. thermoresistible (build 8) TH_1991 (tylF)

annotation: Macrocin-O-methyltransferase
coordinates: 3859731 - 3860531
length: 267

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1991tylF-100% (267)Macrocin-O-methyltransferase
M. thermoresistible (build 8)TH_1990-4e-0827.59% (145) Rmt3 protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4108c-1e-13483.46% (266) methyltransferase MtfB
M. marinum M-----
M. avium 104MAV_3266-1e-12477.57% (272) MtfB protein
M. smegmatis MC2 155MSMEG_0388tylF1e-12484.58% (240) macrocin-O-methyltransferase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


TH_1991|M.thermoresistible__bu      -------VTDRDSRSAYLDLLRRDLTRYGSDELVPVGWNWLHRPVFKIGN
MSMEG_0388|M.smegmatis_MC2_155      ---------------------------------MPVGWDWFHRPLFKIGN
MAB_4108c|M.abscessus_ATCC_199      -----MTVTDYDTRSAYLDLLRQDLTRYGVDELVPVGWNWLHRPFFKFGD
MAV_3266|M.avium_104                MTDRDMRSPFLDTRSAYLDLLRRNLTRYGSDELVPVGWNYLGRPLFSTRK
                                                                     :****::: **.*.  .

TH_1991|M.thermoresistible__bu      LMLVRRRPFDKHKRDLGLDWPVEALTMIGMKRLTSLQECVETVLRDDVPG
MSMEG_0388|M.smegmatis_MC2_155      LMLVRRRPFDPRKRDLGLDWPADALTMIGMTRLTSLQQCVETVITEDVPG
MAB_4108c|M.abscessus_ATCC_199      YVLVRKRAFDAHKRDLGLDWPADALTMIGMQRLTSLQQCVETVLADDVPG
MAV_3266|M.avium_104                LMLVRKRPFNAHARDLGLDWPADALTMIGMQRLTSLQHCVETILKDDIPG
                                     :***:*.*: : ********.:******* ******.****:: :*:**

TH_1991|M.thermoresistible__bu      DLVECGVWRGGASILMRAVLAAYGDEERCVWLADSFAGVPPPDAEKYRAD
MSMEG_0388|M.smegmatis_MC2_155      DLVECGVWRGGASILMRAVLSAYGDESRRVWLCDSFAGVPAPDAAKYKAD
MAB_4108c|M.abscessus_ATCC_199      DLVECGVWRGGASILMRAVLAAYGDTTRSVWLCDSFEGVPPPDTANYKAD
MAV_3266|M.avium_104                DLVECGVWRGGASILMRAVLSAYGDEKRCVWLCDSFEGVPPPDTAHYQAD
                                    ********************:****  * ***.*** ***.**: :*:**

TH_1991|M.thermoresistible__bu      QGDRLHLAAPILAVSEEEVRANFERYNLLDDQVRFLPGWFKDTLHKAPIE
MSMEG_0388|M.smegmatis_MC2_155      KGDRLHLAAPILAVSEQDVRANFQRYGLLDDQVRFVPGWFKDTLHDAPIE
MAB_4108c|M.abscessus_ATCC_199      KGDRLHLAAPILAVTEKNVRANFERYGLLDQQVRFVPGWFKDTLHDAPIE
MAV_3266|M.avium_104                KGIKLHRAAGILAVPEAQVRANFERYGLLDDRVRFVPGWFKDTLQDAPIE
                                    :* :** ** ****.* :*****:**.***::***:********:.****

TH_1991|M.thermoresistible__bu      QIAVLRLDGDLYESTIQALDGLYARLSPGGFCIIDDYHAIDGCRQAVTDF
MSMEG_0388|M.smegmatis_MC2_155      RISILRLDGDLYESTIQALDGLYERLSPGGFCIVDDYHAIDGCRQAVTDY
MAB_4108c|M.abscessus_ATCC_199      QIAVLRLDGDLYESTIQALDGLYARLSPGGFCIIDDYHALDSCKQAVTDY
MAV_3266|M.avium_104                RIAVLRLDGDLYESTIQALDALYPRLSAGGICIIDDYHAIDACRQAVTDY
                                    :*::****************.** ***.**:**:*****:*.*:*****:

TH_1991|M.thermoresistible__bu      RATHGITEDIVEIDGTGVLWRKD
MSMEG_0388|M.smegmatis_MC2_155      RAKHGISAEIVEIDGTGVLWRKE
MAB_4108c|M.abscessus_ATCC_199      RAKHGITAEIMEIDGTGVFWRKE
MAV_3266|M.avium_104                RSEHGVTAPIEEIDGTGVLWRKS
                                    *: **::  * *******:***.