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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1659 | - | 100% (630) | POSSIBLE HYDROLASE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3788c | - | 0.0 | 71.95% (631) | putative hydrolase |
M. gilvum PYR-GCK | Mflv_1201 | - | 0.0 | 76.03% (630) | beta-lactamase domain-containing protein |
M. tuberculosis H37Rv | Rv3762c | - | 0.0 | 72.27% (631) | hydrolase |
M. leprae Br4923 | MLBr_00270 | - | 2e-06 | 29.94% (177) | hypothetical protein MLBr_00270 |
M. abscessus ATCC 19977 | MAB_1312 | - | 0.0 | 61.32% (636) | Beta-lactamase-like |
M. marinum M | MMAR_1608 | - | 0.0 | 72.58% (631) | hydrolase |
M. avium 104 | MAV_0307 | - | 0.0 | 74.48% (631) | metallo-beta-lactamase superfamily protein |
M. smegmatis MC2 155 | MSMEG_6339 | - | 0.0 | 76.39% (631) | metallo-beta-lactamase family protein |
M. ulcerans Agy99 | MUL_4388 | - | 0.0 | 71.29% (620) | hydrolase |
M. vanbaalenii PYR-1 | Mvan_5606 | - | 0.0 | 75.20% (641) | beta-lactamase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb3788c|M.bovis_AF2122/97 MPMEHKPPTAVIQAAHGEHS--LPLHDTTDFDDADRGFIAALSPCVIKAA Rv3762c|M.tuberculosis_H37Rv MPMEHKPPTAVIQAAHGEHS--LPLHDTTDFDDADRGFIAALSPCVIKAA MUL_4388|M.ulcerans_Agy99 MPVDHKPPTAAIETAHGEHS--LPLQDTRDFDDADRGFIAASTPCVVKAA MAV_0307|M.avium_104 --MDHKPPSPVIEAAHHACV--LPFSDDADFRDADRGFIAALSPCVVRGA Mflv_1201|M.gilvum_PYR-GCK --MDSKPPAPTIEAAHREHLGTLPFEDTRDFADADRGFIAAQQPCVITAA Mvan_5606|M.vanbaalenii_PYR-1 --MDSKPPTATIEAAHREHLATLPFDDTRDFADADRGFIAAQQPCVIKAA MMAR_1608|M.marinum_M --MEQTSPSPFIVSNHRDHLSALPFGDTQDFTAADRGFIAKLSPCVVTAA MSMEG_6339|M.smegmatis_MC2_155 --MESNPPSAVVEAAHREHLTTLPFGDRRDFDDADRGFIAALEPCVITAD TH_1659|M.thermoresistible__bu --MEPRPPTDSVEAAHRDHLRTLPFDDTTDFDDADRGFIAALEPGVVTAG MAB_1312|M.abscessus_ATCC_1997 -MAEQTQPTSRILEQNAAAAQELPFANTADQEDADRGFIAALEPGVVRDD MLBr_00270|M.leprae_Br4923 -------------------------------------------------- Mb3788c|M.bovis_AF2122/97 DGRVVWDNDAYSFLDG-AAPTSVHPSLWRQSQLTAKQGLYQVVPGIYQVR Rv3762c|M.tuberculosis_H37Rv DGRVVWDNDAYSFLDG-AAPTSVHPSLWRQSQLTAKQGLYQVVPGIYQVR MUL_4388|M.ulcerans_Agy99 DGRVVWDNDAYSFLDG-PAPTSVHPSLWRQSTLAAKQGLYEVVPAIYQVR MAV_0307|M.avium_104 DGRVVFDNDAYAFLDG-PAPTSVHPSLWRQSTLAAKHGLYEVVPGIYQVR Mflv_1201|M.gilvum_PYR-GCK DGRVVWDNDVYAFLTG-EAPPTVHPSLWRQSTLVAKQGLYEVVPGIYQVR Mvan_5606|M.vanbaalenii_PYR-1 DGRVVWDNDVYAFLTG-DAPTTVHPSLWRQSTLAAKQGLYRVVEGIYQVR MMAR_1608|M.marinum_M DGRVVWDNDSYSFLDE-DAPPSVHPSLWRQSQLCAKQGLYQVVEGIYQVR MSMEG_6339|M.smegmatis_MC2_155 DGRLVWDNDSYRFLDSEQAPASVHPSLWRQSRLCAKQGLYEVVDGIYQVR TH_1659|M.thermoresistible__bu DGRVVWDNDAYAFLAG-EPPTSVHPSLWRQSRLCAEQGLYRVVDGVYQVR MAB_1312|M.abscessus_ATCC_1997 SGKVVWDNDSYAFLQG-ACPGSVHPSLWRQCGLNIRQGLYHVTEGIYQVR MLBr_00270|M.leprae_Br4923 ---------------------------------MAAATLFQVTDSVHFAR *:.*. .:: .* Mb3788c|M.bovis_AF2122/97 GFDISNISFVEGDTGLIVIDP--LVSTEVAAAALDLYRAHRGADRPVVAV Rv3762c|M.tuberculosis_H37Rv GFDISNISFVEGDTGLIVIDP--LVSTEVAAAALDLYRAHRGADRPVVAV MUL_4388|M.ulcerans_Agy99 GFDLSNITFVEGDTGIIVIDP--LVSTEVAAAALTLYRAHRDADRPVVAV MAV_0307|M.avium_104 GLDISNVTFVETDTGIIVIDP--LVSTEVAAAALTLYRTHRGGDRPVVAV Mflv_1201|M.gilvum_PYR-GCK GFDLSNITFVEGDTGIIVIDP--LVSTEVAAAALALYRQHRG-DREVRAV Mvan_5606|M.vanbaalenii_PYR-1 GFDLSNITFVEGDTGIIVIDP--LVSTEVAAAALALYREHRG-DREVRAV MMAR_1608|M.marinum_M GLDLSNISFIEGDAGVIVIDP--LVCTETAAAALALYREHRG-DRAVSAV MSMEG_6339|M.smegmatis_MC2_155 GLDLSNITFVEGDSGVIVIDP--LISTETAAAALALYRAHRG-DRRVTAV TH_1659|M.thermoresistible__bu GLDLSNVTFVEGDTGVIVIDP--LISTETAAAALALYRRHRG-DRAVRAV MAB_1312|M.abscessus_ATCC_1997 GLDISNMTLVEGERGVIVIDP--LVSVETAAAGLALYRHHRG-DRPVTGL MLBr_00270|M.leprae_Br4923 G-DAVNWALVADDTGVMLIDTGYPGDRDDVVASLRQLGYEAG---DVRAI * * * ::: : *:::**. : ..*.* . . * .: Mb3788c|M.bovis_AF2122/97 IYTHSHVDHFGGVLGGTTQADVDAGKVAVLAPEGFTAHAVQENIYAGSAM Rv3762c|M.tuberculosis_H37Rv IYTHSHVDHFGGVLGVTTQADVDAGKVAVLAPEGFTAHAVQENIYAGSAM MUL_4388|M.ulcerans_Agy99 IYTHSHVDHFGGVLGVTSQDDVDAGKVKVLAPQGFTEHAVQENVYAGPAM MAV_0307|M.avium_104 IYTHSHVDHFGGVLGVATQADVDAGRVAVLAPEGFVEHAVQENVYAGPAM Mflv_1201|M.gilvum_PYR-GCK IYTHSHVDHFGGVLGVTTQADVDAGRVAVFAPEGFTAHAVQENVYAGTAM Mvan_5606|M.vanbaalenii_PYR-1 IYTHSHVDHFGGVLGVTSQADVDAGRVAVLAPEGFTAHAVQENVYAGTAM MMAR_1608|M.marinum_M IYTHSHVDHFGGVFGVTTQADVDAGKVAVLAPEGFVEHAVQENVYAGTAM MSMEG_6339|M.smegmatis_MC2_155 IYTHSHVDHFGGVLGVTTQADVDAGRVVVIAPEHFTTHAVQENVYAGTAM TH_1659|M.thermoresistible__bu IHTHSHVDHFGGVLGVTTPADVESGRVAVIAPEGFVEHAVAENVYAGTAM MAB_1312|M.abscessus_ATCC_1997 IYTHSHVDHFGGALGVTSPEDVATGRCPVLAPAGLLEHAVAENVYAGPAM MLBr_00270|M.leprae_Br4923 LLTHAHIDHMGSAIWFAS-----KHRTPVYCHADEVGHTKREYLEQVSLL : **:*:**:*..: :: : * . *: * : . : Mb3788c|M.bovis_AF2122/97 MRRAGYMYGTVLARGLRGHVGCGLGQTLSTGEVSLVVPTVDITETGETHT Rv3762c|M.tuberculosis_H37Rv MRRAGYMYGTVLARGLRGHVGCGLGQTLSTGEVSLVVPTVDITETGETHT MUL_4388|M.ulcerans_Agy99 TRRATYMYGTLLERGPQAQVGCGLGQTPSTGEVAIINPTVDIRSTGEKHT MAV_0307|M.avium_104 LRRATYMYGTLLPRGLFDHVGCGLGQAASMGEVALIVPTVDIRETGETHT Mflv_1201|M.gilvum_PYR-GCK TRRAAYMYGTVLERGPQGQVGCGLGQTPSTGEVAIIVPTVDIRETGEVHT Mvan_5606|M.vanbaalenii_PYR-1 TRRAAYMYGTVLERGPKGQVGCGLGQTPSTGEVAIIVPTVDIRETGETHT MMAR_1608|M.marinum_M ARRAAYMYGAVLPRGPQGQVGCGLGQTPSLGEVGLIVPTIDITSTGEIHT MSMEG_6339|M.smegmatis_MC2_155 ARRAAYMYGAALARGPLGQVGCGLGQVPSTGEVALIVPTLDIRETGEIHS TH_1659|M.thermoresistible__bu ARRASYMYGTMLEVGPRGQVGCGLGQRTSTGEVGMIVPTLDIRHTGEHHT MAB_1312|M.abscessus_ATCC_1997 TRRAVYMYGAFLPRGPLGQVGAGLGQTNSLGTVTLIPPTVDITHTGQEET MLBr_00270|M.leprae_Br4923 N------------------------------------------------- Mb3788c|M.bovis_AF2122/97 IDGVEIEFQMAPGTEAPAEMHFYFPRFRALCMAENATHNLHNLLTLRGAL Rv3762c|M.tuberculosis_H37Rv IDGVEIEFQMAPGTEAPAEMHFYFPRFRALCMAENATHNLHNLLTLRGAL MUL_4388|M.ulcerans_Agy99 IDRVEIEFQMAPGTEAPPRCTSYFPKFRALCMAENATHNLHNLLTLRGAL MAV_0307|M.avium_104 IDGVEIEFQMAPGTEAPAEMHFYFPQFRALCMAENATHNLHNLLTLRGAL Mflv_1201|M.gilvum_PYR-GCK VDGVEIEFQMAPGTEAPAEMHFYFPRFRALCMAENATHNLHNLLTLRGAL Mvan_5606|M.vanbaalenii_PYR-1 IDGVEIEFQMAPGTEAPAEMHFYFPRFRALCMAENATHNLHNLLTLRGAL MMAR_1608|M.marinum_M IDGVDIEFQMAPGTEAPAEMHFYFPKFRALCMAENATHNLHNLLTLRGAL MSMEG_6339|M.smegmatis_MC2_155 IDGVDIEFQMAPGTEAPAEMHFYFPKFRALCMAENATHNLHNLLTLRGAL TH_1659|M.thermoresistible__bu VDGIEIEFQMTPNSEAPAEMHFFFPRYRALCMAENATHNLHNLLTLRGAL MAB_1312|M.abscessus_ATCC_1997 VDGVRMVFQLTPGTEAPAEMNFHFPERRALCMAENATHTLHNLLTLRGAL MLBr_00270|M.leprae_Br4923 -----------------IAMRVWQPR-----WAIWSGHVLR-----SGGL *. * : * *: *.* Mb3788c|M.bovis_AF2122/97 VRDPRAWSGYLTEAIDTFADRTDVVFASHHWPTWGREKIVEFLSQQRDMH Rv3762c|M.tuberculosis_H37Rv VRDPRAWSGYLTEAIDTFADRTDVVFASHHWPTWGREKIVEFLSQQRDMY MUL_4388|M.ulcerans_Agy99 VRDPHAWSGYLTEAIDTFADRADVVFASHHWPTWGRERIVEFLALQRDLY MAV_0307|M.avium_104 VRDPRAWSGYLTEAIDTFADRADVVFASHHWPTWGRDGIVEFLSLQRDLY Mflv_1201|M.gilvum_PYR-GCK VRDPHGWAGYLTEAIDTFVDRADVVFASHHWPTWGSERIVEFLSLQRDLY Mvan_5606|M.vanbaalenii_PYR-1 VRDPHGWAGYLTEAIDTFADRADVVFASHHWPTWGKDRIVEFLSLQRDLY MMAR_1608|M.marinum_M VRDPHAWSGYLTEAIDTFADRTDVVFASHHWPTWGREGIVEFLSLQRDLY MSMEG_6339|M.smegmatis_MC2_155 VRDPHGWAGYLTEAIDSFADRTDVVFASHHWPTWGRDNIVEYLSLQRDLY TH_1659|M.thermoresistible__bu VRDPHAWANYLTEAIDLFAHRSEVAFASHHWPTWGTDRIVEYLSLQRDLY MAB_1312|M.abscessus_ATCC_1997 VRDPHVWARYITEAINLYARDSDVVFASHHWPTWGTERLVEYLALQRDLY MLBr_00270|M.leprae_Br4923 IRG----------------------------------GIPTAQPLTAETA :*. : . : Mb3788c|M.bovis_AF2122/97 SYLHDQTLRLLNQGYTGVEIAEMFQLPPALQRAWHTHGYYGSVSHNVKAI Rv3762c|M.tuberculosis_H37Rv SYLHDQTLRLLNQGYTGVEIAEMFQLPPALQRAWHTHGYYGSVSHNVKAI MUL_4388|M.ulcerans_Agy99 AYLHDQTLRLLNQGYTGVEIAEMFQMPPALEQAWHTRGYYGSVNHNVKAV MAV_0307|M.avium_104 AYLHDQTLRLLNQGHTGVEIAEMFRLPPALERAWHARGYYGSVSHNVKAI Mflv_1201|M.gilvum_PYR-GCK AYLHDQTLRQLNQGYTGIEIAESFAMPPALENAWHARGYYGSVSHNVKAV Mvan_5606|M.vanbaalenii_PYR-1 AYLHDQTLRQLNQGFTGIEIAEAFAMPPALERAWHARGYYGSVSHNVKAV MMAR_1608|M.marinum_M AYLHDQTLRLLNQGYTGIEIAENFRMPPALEKAWHTHGYYGSVNHNVKAV MSMEG_6339|M.smegmatis_MC2_155 AYLHDQTLRLINQGHTGIEIAEQFELPPALQAAWHTHGYYGSVSHNVKAV TH_1659|M.thermoresistible__bu AYLHDQTLRLLNRGHTGIEIAEQLTLPPALERAWHTRGYYGSVSHNVKAI MAB_1312|M.abscessus_ATCC_1997 AYLHDQTLRMLNQGLVGSEIAEDLQLPPAIAGAWHTRGYYGSVSHNVKAI MLBr_00270|M.leprae_Br4923 AGLPGHPMAIFTPGHTG-----------------------GHCSYVVDGV : * .:.: :. * .* * .: *..: Mb3788c|M.bovis_AF2122/97 YQRYMGWFDGNPGWLWPHPPEALAPRYVDALGGIDRVLELAREAFDAGDF Rv3762c|M.tuberculosis_H37Rv YQRYMGWFDGNPGWLWPHPPEALAPRYVDALGGIDRVLELAREAFDAGDF MUL_4388|M.ulcerans_Agy99 YQRYMGWFDGNPGRLWPHPPEELAPRYVEAMGGIDQVVELAQQAFDSGDF MAV_0307|M.avium_104 YQRYMGWFDGNPARLWPHPPEALGPRYVAAMGGIDRVVDLAQQAFDSGDY Mflv_1201|M.gilvum_PYR-GCK YQRYMGWFDGNPGRLWPHPPEAIGPRYVAAMGGIDRVVELAQAAVDEGDF Mvan_5606|M.vanbaalenii_PYR-1 YQRYMGWFDGNPARLWPHPPEAIGPRYVAAMGGIDRVVELAKGAFDEGDF MMAR_1608|M.marinum_M YQRYMGWFDGNPARLWQHPPEAIGPRYVEAIGGIDRTLELAQKAYDTGDY MSMEG_6339|M.smegmatis_MC2_155 YQRYMGWFDGNPGRLWQHPPEALGPRYVDAMGGIDRVVELARRAFDSGDY TH_1659|M.thermoresistible__bu YQRYMGWFDGNPARLWPHPPEASGPRYVAAMGGADRVVELARQAFDDGDF MAB_1312|M.abscessus_ATCC_1997 YQRYMGWFDGNPAHLWEHPPVENARRHVEFMGGAQEVLRKARIAFEQGDY MLBr_00270|M.leprae_Br4923 LISGDALITGHP------------------------------------LL . : *:* Mb3788c|M.bovis_AF2122/97 RWAATLLDHAVFADSEHAAARGLYADTLEQLAYGAECATWRNFFLTGAAE Rv3762c|M.tuberculosis_H37Rv RWAATLLDHAVFADSEHAAARGLYADTLEQLAYGAECATWRNFFLTGAAE MUL_4388|M.ulcerans_Agy99 RWAATLLDHAVFTDSEHSAARTLYADTLEQLAYGAENAVWRNFFLCGAAE MAV_0307|M.avium_104 RWAATLLDHAMFTDGEHVGARELYADTLEQLAYGAENATWRNFFLSGATE Mflv_1201|M.gilvum_PYR-GCK RWAATLLDHAIFTDENHAGTRALYADTLEQLAYGAETATWRNFFLGGATE Mvan_5606|M.vanbaalenii_PYR-1 RWAATLLDHAMFTDENHAGARALYADTLEQLAYGAETATWRNFFLGGATE MMAR_1608|M.marinum_M RWAATLLDHIVFTDEQHAGARKLYADTLTQLAYGAECATWRNFFLSGATE MSMEG_6339|M.smegmatis_MC2_155 RWAATLLDHAVFTDEHHRGARALYAEVLEQLAYGAENAVWRNFFLGGATE TH_1659|M.thermoresistible__bu RWAATLLDHVVFTDANHAGARELHADTLEQLGYGSENATWRNFFLSGAAE MAB_1312|M.abscessus_ATCC_1997 RWVAQVLNYVIFADPANDAAKALQANCFEQLGYGAENATWRNFYLMGAYE MLBr_00270|M.leprae_Br4923 RHRGPQLLTAVFSHSQKQCLRSLDALGLLETRILAP----------GHGE * . * :*:. : : * * : : : * * Mb3788c|M.bovis_AF2122/97 LRDGNPGSSGQVP-APTFFAQLTPDQIFDVLAISINGPRAWDLDLAIDFT Rv3762c|M.tuberculosis_H37Rv LRDGNPGSSGQVP-APTFFAQLTPDQIFDVLAISINGPRAWDLDLAIDFT MUL_4388|M.ulcerans_Agy99 LRDGKFGTAVQTT-SPTLLTQLTPEQIFDSLAIRIDGPRSWDLDLTIDVT MAV_0307|M.avium_104 LRDGNFGTAGQVT-SPTMLAQLTPEQIFDGLAIRVNGPRSWGLDITVDVT Mflv_1201|M.gilvum_PYR-GCK LREGNFGTPVQAD-SAAMLGQLSPEQMFDVLAISVNGPRAWDLDLAIDVT Mvan_5606|M.vanbaalenii_PYR-1 LRVGNFGTPTQTT-STSMVAQLTPEQMFDVLAISVNGPRAWDLDLAVDVT MMAR_1608|M.marinum_M LAAGNMGTPTQAASSASLLGQLTPEQMFDVLAISVNGPKAWDLSLALDVS MSMEG_6339|M.smegmatis_MC2_155 LRDGKFGTPTAPS-SPTLLAQLTPEQIFDAVAINVNGPRAWDLDLAIDVT TH_1659|M.thermoresistible__bu LRHGNFGTGTGTA-SPAMLAQLRPEQIFDSLAINVDGPRAWDLDLAIDIT MAB_1312|M.abscessus_ATCC_1997 LRHGSVGTPVSIG-SPSMMAALSVDQIFDALSLRVNGPKAWDERFVSDWR MLBr_00270|M.leprae_Br4923 LWHGPIREATEAA--LKQAGALTR-------------------------- * * * Mb3788c|M.bovis_AF2122/97 FTEPD----------------VNYRLTLRNGVLIHRKLP--ADPATANAT Rv3762c|M.tuberculosis_H37Rv FTEPD----------------VNYRLTLRNGVLIHRKLP--ADPATANAT MUL_4388|M.ulcerans_Agy99 FEDLN----------------ANYRLALSNGVLVHRKVA--ADEATASAT MAV_0307|M.avium_104 LADTA----------------VNHRLALRNGVLVQRKVP--ADPTTATVT Mflv_1201|M.gilvum_PYR-GCK FLDTD----------------TNYRLTLRNGVLVYRKVA--ADEESAHAT Mvan_5606|M.vanbaalenii_PYR-1 FLTAASRESGTAASRGSGTAATNYRLTLRNGVLVYRAAA--ADEASAHVT MMAR_1608|M.marinum_M FDDLA----------------VNYRLTLRNGVLVYRKAS--ADASTANAT MSMEG_6339|M.smegmatis_MC2_155 FADTG----------------DTYRLTLRNGVLVHRRTE--PDPSSAHAS TH_1659|M.thermoresistible__bu FADPN-----------FTDTDVNHRLTLRHGVLVHRRAP--ADG-RAGAR MAB_1312|M.abscessus_ATCC_1997 FTDED----------------RVHRVELRNGVLVHYDLPETANAPQPAVA MLBr_00270|M.leprae_Br4923 -------------------------------------------------- Mb3788c|M.bovis_AF2122/97 VTVGDKVRLVAAALGD-----ISSPGFEVFGDRTVLQTFLSVLDRPDSAF Rv3762c|M.tuberculosis_H37Rv VTVGDKVRLVAAALGD-----ISSPGFEVFGDRTVLQTFLSVLDRPDSAF MUL_4388|M.ulcerans_Agy99 VKLQNKSRLLAVAMGD-----VTSPGLEVSGDESVLQTLAGVLD------ MAV_0307|M.avium_104 VRLANKIRLLALAAGD-----FASPGLELTGDRGALQSLVGALDAPDPDF Mflv_1201|M.gilvum_PYR-GCK LRLASKLRLLTLAAGD-----DSSPGLEIAGDAGVLSSLVSVLDKPDPNF Mvan_5606|M.vanbaalenii_PYR-1 IRLANKLRLLTLAAGD-----TTSPGLEIAGDAEVLTALVSVLDKPDPSF MMAR_1608|M.marinum_M IKLAGKLRLVTLAAGD-----QTSPGVEISGDPQALQSLVSVLDRPNPDF MSMEG_6339|M.smegmatis_MC2_155 VTVADRMRLLTFFIGD-----TAMPGLQVTGAPDVLQSFLRVLDRPDPNF TH_1659|M.thermoresistible__bu VRVAGTGRLLALTAGD-----VSSPGLQITGDLQVLQALLDVLDRPDPAF MAB_1312|M.abscessus_ATCC_1997 FTLTRTGLVKLLLAGEDPGRLFASGEITVEGDASGFARLVSVLDEPDPGF MLBr_00270|M.leprae_Br4923 -------------------------------------------------- Mb3788c|M.bovis_AF2122/97 NIVTP Rv3762c|M.tuberculosis_H37Rv NIVTP MUL_4388|M.ulcerans_Agy99 ----- MAV_0307|M.avium_104 NIVTP Mflv_1201|M.gilvum_PYR-GCK NIVTP Mvan_5606|M.vanbaalenii_PYR-1 NIITP MMAR_1608|M.marinum_M NIVTP MSMEG_6339|M.smegmatis_MC2_155 SIVTP TH_1659|M.thermoresistible__bu DIVTP MAB_1312|M.abscessus_ATCC_1997 AIVTP MLBr_00270|M.leprae_Br4923 -----