For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_1448 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 2751534 - 2753570
length: 679

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1448-100% (679)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2425-0.089.91% (634) hypothetical protein Mb2425
M. gilvum PYR-GCKMflv_2676-0.086.28% (678) glycoside hydrolase 15-related
M. tuberculosis H37RvRv2402-0.089.91% (634) hypothetical protein Rv2402
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1643-0.084.49% (632) putative glycosyl hydrolase
M. marinum MMMAR_3721-0.084.74% (688) glycosyl hydrolase
M. avium 104MAV_1780-0.087.63% (671) glycoside hydrolase
M. smegmatis MC2 155MSMEG_4535-0.091.19% (658) glycoside hydrolase
M. ulcerans Agy99MUL_3664-0.084.59% (688) glycosyl hydrolase
M. vanbaalenii PYR-1Mvan_3877-0.088.79% (660) glycoside hydrolase 15-related

CLUSTAL 2.0.9 multiple sequence alignment


TH_1448|M.thermoresistible__bu      MVLQHSSADESAARARRASPAGLGAQS----------KASFSVTEPVPYA
MSMEG_4535|M.smegmatis_MC2_155      MVLQQTEPTDGADRK----------AS----------DGPLTVTAPVPYA
Mflv_2676|M.gilvum_PYR-GCK          MALQQSEASDALSTN------GESSSQ----------PSALDLPSATPNY
Mvan_3877|M.vanbaalenii_PYR-1       MVLPQTETSDGVSPN------GDGG------------AFALSSPAAYP--
Mb2425|M.bovis_AF2122/97            ----------------------------------------MALS------
Rv2402|M.tuberculosis_H37Rv         ----------------------------------------MALS------
MMAR_3721|M.marinum_M               MVLHAEHADEDVELTVEPTEAPHAAPATQIPALDGAPAASVELSQHGISP
MUL_3664|M.ulcerans_Agy99           MVLHAEHADEDVELTVEPTEAPHAAPATQIPALDGAPAASVELSQHGISP
MAV_1780|M.avium_104                MVLHVQPDDQPADTMPE--EPFRAAPATSMES-------SIDLRTPGPLA
MAB_1643|M.abscessus_ATCC_1997      MVSSLDP--------------------------------ELSLEGLLSSQ
                                                                            .         

TH_1448|M.thermoresistible__bu      PTGTLRNPFPPIADYGFLSDCETTCLISSSGSVEWLCVPRPDSPSVFGAI
MSMEG_4535|M.smegmatis_MC2_155      AGPTLRNPFPPIADYGFLSDCETTCLISSAGSVEWLCVPRPDSPSVFGAI
Mflv_2676|M.gilvum_PYR-GCK          SPGPLRNPFPPIADYAFLSDCETQCLISSAGSVEWLCVPRPDSPSVFGAI
Mvan_3877|M.vanbaalenii_PYR-1       SSGPLRNPFPPIADYAFLSDCETQCLISSAGSVEWLCVPRPDSPSVFGAI
Mb2425|M.bovis_AF2122/97            SSSPLRNPFPPIADYAFLSDWETTCLISPAGSVEWLCVPRPDSPSVFGAI
Rv2402|M.tuberculosis_H37Rv         SSSPLRNPFPPIADYAFLSDWETTCLISPAGSVEWLCVPRPDSPSVFGAI
MMAR_3721|M.marinum_M               SSASLRNPFPPIADYAFLSDWETTCLISPAGSVEWMCVPRPDSPSVFGAI
MUL_3664|M.ulcerans_Agy99           SSASLRNPFPPIADYAFLSDWETTCLISPAGSVEWMCVPRPDSPSVFGAI
MAV_1780|M.avium_104                PNAALRNPFPPIADYAFLSDWETTCLISPAGSVEWMCVPRPDSPSVFGAI
MAB_1643|M.abscessus_ATCC_1997      SPVQRRGPFPPIADYAFLSDWENTCLIASNGSVEWMCVPRPDSPSIFGAV
                                    .    *.********.**** *. ***:. *****:*********:***:

TH_1448|M.thermoresistible__bu      LDRGAGHFRLGPYGVSVPAARRYLPGSLILETTWQTHTGWLIVRDALVMG
MSMEG_4535|M.smegmatis_MC2_155      LDRGAGHFRLGPYGVSVPAARRYLPGSLILETTWQTHTGWLIVRDALVMG
Mflv_2676|M.gilvum_PYR-GCK          LDRGAGHFRLGPYGVSVPAARRYLPGSLILETTWQTHTGWVIVRDALVMG
Mvan_3877|M.vanbaalenii_PYR-1       LDRGAGHFRLGPYGVSVPAARRYLPGSLILETTWQTPTGWVIVRDALVMG
Mb2425|M.bovis_AF2122/97            LDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
Rv2402|M.tuberculosis_H37Rv         LDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
MMAR_3721|M.marinum_M               LDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
MUL_3664|M.ulcerans_Agy99           LDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
MAV_1780|M.avium_104                LDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMG
MAB_1643|M.abscessus_ATCC_1997      LDRGAGHFRIAPYGHNVPAARRYLPGSLMVETTWQTKTGWLTVRDALVLG
                                    ***.*****:.*** .**:*********::****** ***: ******:*

TH_1448|M.thermoresistible__bu      PWHDIETRSRTHRRTPMDWDAEHILLRTVRCVSGTVELVMNCEPAFDYHR
MSMEG_4535|M.smegmatis_MC2_155      PWHDIDTRSRTHRRTPMDWDAEHILLRTVRCVSGTVELVMSCEPAFDYHR
Mflv_2676|M.gilvum_PYR-GCK          PWHDLETRSRTHRRTPMDWDAEHILLRTVRCVSGTVELVMSCEPSFDYHR
Mvan_3877|M.vanbaalenii_PYR-1       PWHDLDTRSRTHRRTPMDWDAEHILLRTVRCVSGTVELVMSCEPSFDYHR
Mb2425|M.bovis_AF2122/97            KWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHR
Rv2402|M.tuberculosis_H37Rv         KWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHR
MMAR_3721|M.marinum_M               PWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHR
MUL_3664|M.ulcerans_Agy99           PWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHR
MAV_1780|M.avium_104                PWHDLERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHR
MAB_1643|M.abscessus_ATCC_1997      PWHDVDSRSKTHKRTPTDWDAEHILLRTVRCVSGTVEVLMNCEPAFDYHR
                                     ***:: **:**:*** ********************::*.***:*****

TH_1448|M.thermoresistible__bu      NNATWEYSAAAYGEAIARATENPDSHPTLRLTTNLRIGLEGREARARTRL
MSMEG_4535|M.smegmatis_MC2_155      VSATWEYSGPAYGEAIARASRNPDSHPTLRLTTNLRIGIEGREARARTRL
Mflv_2676|M.gilvum_PYR-GCK          TSAHWEYSAQAYGEAIARATKNPDSHPTLRLTTNLRIGLEGREARARTRL
Mvan_3877|M.vanbaalenii_PYR-1       TSAHWEYSAQAYGEAIARATKNPDSHPTLRLTTNLRIGLEGREARARTRL
Mb2425|M.bovis_AF2122/97            LGATWEYSAEAYGEAIARANTEPDAHPTLRLTTNLRIGLEGREARARTRM
Rv2402|M.tuberculosis_H37Rv         LGATWEYSAEAYGEAIARANTEPDAHPTLRLTTNLRIGLEGREARARTRM
MMAR_3721|M.marinum_M               LGATWEYSANAYGEAIARASKQPDAHPTLRLTTNLRIGLEGREARARTRM
MUL_3664|M.ulcerans_Agy99           LGATWEYSANAYGEAIARASKQPDAHPTLRLTTNLRIGLEGREARARTRM
MAV_1780|M.avium_104                VGATWEYSANAYGEAIARATKQPDAHPTLRLTTNLRIGLEGREARARTRM
MAB_1643|M.abscessus_ATCC_1997      EGAVWEYSGDGYGEAICRAAKNPDANPTLKLTTNLRLGLEGREARARTRL
                                     .* ****. .*****.**  :**::***:******:*:**********:

TH_1448|M.thermoresistible__bu      KEGDNVFVALSWSKHPAPQTYEEAAEKMWQTSEAWRQWINIGNFPDHPWR
MSMEG_4535|M.smegmatis_MC2_155      TEGDNVFVALSWSKHPAPQTYEEAADKMWKTSEAWRQWINVGDFPDHPWR
Mflv_2676|M.gilvum_PYR-GCK          KEGDNVFVALSWSKHPAPQNFEEATDKMWKTSECWRQWINVGDFPDHPWR
Mvan_3877|M.vanbaalenii_PYR-1       KEGDNVFVALSWSKHPAPQNYQEAADKMWTTSECWRQWINVGDFPDHPWR
Mb2425|M.bovis_AF2122/97            KEGDDVFVALSWTKHPPPQTYDEAADKMWQTTECWRQWINIGNFPDHPWR
Rv2402|M.tuberculosis_H37Rv         KEGDDVFVALSWTKHPPPQTYDEAADKMWQTTECWRQWINIGNFPDHPWR
MMAR_3721|M.marinum_M               KEGDDVFVALSWTKHPAPQTYQEAAQKMWQTTECWRQWINIGNFPDHPWR
MUL_3664|M.ulcerans_Agy99           KEGDDVFVALSWTKHPAPQTYQEAARKMWQTTECWRQWINIGNFPDHPWR
MAV_1780|M.avium_104                KEGDDVFVALSWTKHPPPQTYQEAADKMWQTTECWRQWINIGNFPDHPWR
MAB_1643|M.abscessus_ATCC_1997      TEGDNVFVALSWSKHPVPQTYAEAADKMWKTAEAWRQWINIGEFPDHPWR
                                    .***:*******:*** **.: **: *** *:*.******:*:*******

TH_1448|M.thermoresistible__bu      GYLQRSALTLKGLTYSPTGALLAASTTSLPETPQGERNWDYRYAWVRDST
MSMEG_4535|M.smegmatis_MC2_155      AYLQRSALTLKGLTYSPTGALLAAPTTSLPETPQGERNWDYRYSWIRDST
Mflv_2676|M.gilvum_PYR-GCK          AYLQRSALTLKGLTYSPTGALLAAPTTSLPETPQGERNWDYRYAWVRDST
Mvan_3877|M.vanbaalenii_PYR-1       AYLQRSALTLKGLTYSPTGALLAAPTTSLPESPQGERNWDYRYAWVRDST
Mb2425|M.bovis_AF2122/97            AYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWIRDST
Rv2402|M.tuberculosis_H37Rv         AYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWIRDST
MMAR_3721|M.marinum_M               AYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWVRDST
MUL_3664|M.ulcerans_Agy99           AYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWVRDST
MAV_1780|M.avium_104                AYLQRSALTLKGLTYSPTGALLAASTTSLPETPQGERNWDYRYAWVRDST
MAB_1643|M.abscessus_ATCC_1997      SYLQSSALVLKGLAYSPTGALLAASTTSLPETPGGVRNWDYRYSWVRDST
                                    .*** ***.****:**********.******:* * *******:*:****

TH_1448|M.thermoresistible__bu      FALWGLYTLGLDREADDFFAFIADVSGANNGERHPLQVMYAVGGERTLVE
MSMEG_4535|M.smegmatis_MC2_155      FALWGLYTLGLDREADDFFSFIADVSGANNGERHPLQVMYGVGGERSLVE
Mflv_2676|M.gilvum_PYR-GCK          FALWGLYTLGLDREADDFFAFIADVSGANNGQRHPLQVMYGVGGERTLVE
Mvan_3877|M.vanbaalenii_PYR-1       FALWGLYTLGLDREADDFFAFIADVSGANNGDRHPLQVMYGVGGERSLVE
Mb2425|M.bovis_AF2122/97            FALWGLYTLGLDREADDFFAFIADVSGANNNERHPLQVMYGVGGERSLVE
Rv2402|M.tuberculosis_H37Rv         FALWGLYTLGLDREADDFFAFIADVSGANNNERHPLQVMYGVGGERSLVE
MMAR_3721|M.marinum_M               FALWGLYTLGLDREADDFFAFIADVSGANHNERHPLQVMYGVGGERSLVE
MUL_3664|M.ulcerans_Agy99           FALWGLYTLGLDREADDFFAFIADVSGANHNERHPLQVMYGVGGERSLVE
MAV_1780|M.avium_104                FALWGLYTLGLDREADDFFAFIADVSGANNNERHPLQVMYGVGGERSLVE
MAB_1643|M.abscessus_ATCC_1997      FALWGLYTLGLDREADDFFSFIADASGANNGEKHPLQVMYGVGGERTLTE
                                    *******************:****.****:.::*******.*****:*.*

TH_1448|M.thermoresistible__bu      EELPHLSGYDNARPVRIGNGAYNQRQHDIWGTMLDSVYLHAKSREQIPPT
MSMEG_4535|M.smegmatis_MC2_155      EELHHLSGYDNSRPVRIGNGAYNQRQHDIWGTMLDSVYLHAKSREQIPDA
Mflv_2676|M.gilvum_PYR-GCK          EELNHLSGYDNSRPVRIGNGAFDQMQHDIWGTMLDSVYLHTKSREQIPET
Mvan_3877|M.vanbaalenii_PYR-1       EELNHLSGYDNARPVRIGNGAYNQMQHDIWGTLLDSVYLHTKSREQIPET
Mb2425|M.bovis_AF2122/97            AELHHLSGYDHARPVRIGNGAYNQRQHDIWGSILDSFYLHAKSREQVPEN
Rv2402|M.tuberculosis_H37Rv         AELHHLSGYDHARPVRIGNGAYNQRQHDIWGSILDSFYLHAKSREQVPEN
MMAR_3721|M.marinum_M               EELNHLSGYDHARPVRIGNGAYNQDQHDIWGSILDSFYLHAKSREQVPET
MUL_3664|M.ulcerans_Agy99           EELNHLSGYDHARPVRIGNGAYNQDQHDIWGSILDSFYLHAKSREQVPET
MAV_1780|M.avium_104                EELHHLSGYDHARPVRIGNGAYDQVQHDIWGSILDSFYLHAKSREQVPET
MAB_1643|M.abscessus_ATCC_1997      GELPHMSGYDGARPVRIGNGAFDQIQHDIWGTMLDSVYVHAKSREQIPAT
                                     ** *:**** :*********::* ******::***.*:*:*****:*  

TH_1448|M.thermoresistible__bu      LWPVLKQQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGSKL
MSMEG_4535|M.smegmatis_MC2_155      LWPVLKNQVEEAIKHWKEPDRGIWEVRGEPQHFTSSKIMCWVALDRGSKL
Mflv_2676|M.gilvum_PYR-GCK          LWPVLKEQVEEAIKHWREPDRGIWEVRGEPQHFTSSKIMCWVALDRGSKL
Mvan_3877|M.vanbaalenii_PYR-1       LWPVLKEQVEEAVKHWREPDRGIWEVRGEPQHFTSSKIMCWVALDRGAKL
Mb2425|M.bovis_AF2122/97            LWPVLKRQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKL
Rv2402|M.tuberculosis_H37Rv         LWPVLKRQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKL
MMAR_3721|M.marinum_M               LWPVLKRQVEEAITHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKL
MUL_3664|M.ulcerans_Agy99           LWPVLKRQVEEAITHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKL
MAV_1780|M.avium_104                LWPVLKKQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKL
MAB_1643|M.abscessus_ATCC_1997      LWPILKNQAEEAARHWREPDRGIWEVRGEPQHFTSSKIMCWVAMDRGAKL
                                    ***:**.*.***  **:********************:*****:***:**

TH_1448|M.thermoresistible__bu      AELQGEKSYAQQWRAIAEEIKADVLANGVDERGVFVQRYGSKALDASLLL
MSMEG_4535|M.smegmatis_MC2_155      AELQGEKSYAQQWRAIAEEIKADVLARGVDKRGVLTQRYGDDALDASLLL
Mflv_2676|M.gilvum_PYR-GCK          ADLEGEKTYAHQWREIADEIKADILEHGVDERGVLTQRYGDPALDASLLL
Mvan_3877|M.vanbaalenii_PYR-1       AEFEGEKSYAQQWRAIAEEIKADILEHGVDERGVLTQRYGHDALDASLLL
Mb2425|M.bovis_AF2122/97            AERQGEKSYAQQWRAIADEIKADILEHGVDSRGVFTQRYGDEALDASLLL
Rv2402|M.tuberculosis_H37Rv         AERQGEKSYAQQWRAIADEIKADILEHGVDSRGVFTQRYGDEALDASLLL
MMAR_3721|M.marinum_M               AERQGEKSYAQQWHQIADEIKADILEHGVDSRGVFTQRYGDDALDASLLL
MUL_3664|M.ulcerans_Agy99           AERQGEKSYAQQWHQIADEIKADILEHGVDSRGVFTQRYGDDALDASLLL
MAV_1780|M.avium_104                AERQGEKSYAQQWRNIAEEIKADILAHGVDSRGVFTQRYGSDALDASLLL
MAB_1643|M.abscessus_ATCC_1997      AEMHGEKSYAQQWRAVADEIKEDILEHGVDERGVLVQRYGSTALDASLLL
                                    *: .***:**:**: :*:*** *:* .***.***:.****  ********

TH_1448|M.thermoresistible__bu      VPLVRFLPPDDPRVRATVLAIADELTEEGLVLRYRVEETDDGLSGEEGTF
MSMEG_4535|M.smegmatis_MC2_155      AVLTRFLPADDPRIRATVLAIADELTEDGLVLRYRVEETDDGLAGEEGTF
Mflv_2676|M.gilvum_PYR-GCK          AVLTRFLPPDDPRIRATVNAIADELTEEGLVLRYRVEETDDGLSGEEGTF
Mvan_3877|M.vanbaalenii_PYR-1       AVLTRFLPPDDPRIRATVLAIADELTEEGLVLRYRVEETDDGLSGEEGTF
Mb2425|M.bovis_AF2122/97            VVLTRFLPPDDPRVRNTVLAIADELTEDGLVLRYRVHETDDGLSGEEGTF
Rv2402|M.tuberculosis_H37Rv         VVLTRFLPPDDPRVRNTVLAIADELTEDGLVLRYRVHETDDGLSGEEGTF
MMAR_3721|M.marinum_M               VVLTRFLPPDDPRVRNTVLAIANELTEEGLVLRYRVEETDDGLSGEEGTF
MUL_3664|M.ulcerans_Agy99           VVLTRFLPPDDPRVRNTVLAIANELTEEGLVLRYRVEETDDGLSGEEGTF
MAV_1780|M.avium_104                VVLTRFLPPDDPRVRNTVLAIADELTQEGLVLRYRVEETDDGLSGEEGTF
MAB_1643|M.abscessus_ATCC_1997      AVLNRFLPSDDPRIRATVLAIADELTHDGLVLRYRVEETDDGLSGEEGTF
                                    . * ****.****:* ** ***:***.:********.******:******

TH_1448|M.thermoresistible__bu      TICSFWLVSALVEIGEVRRAKHLCERLLSFASPLHLYAEEIEPRTGRHLG
MSMEG_4535|M.smegmatis_MC2_155      TICSFWLVSALVEIGEISRAKHLCERLLSFASPLHLYAEEIEPRTGRHLG
Mflv_2676|M.gilvum_PYR-GCK          TICSFWLVSALVEIGEIHRARHLCERLLSFASPLHLYAEEIEPRTGRHLG
Mvan_3877|M.vanbaalenii_PYR-1       TICSFWLVSALVEIGEIHRARHLCERLLSFASPLHLYAEEIEPRTGRHLG
Mb2425|M.bovis_AF2122/97            TICSFWLVSALVEIGEVGRAKRLCERLLSFASPLLLYAEEIEPRSGRHLG
Rv2402|M.tuberculosis_H37Rv         TICSFWLVSALVEIGEVGRAKRLCERLLSFASPLLLYAEEIEPRSGRHLG
MMAR_3721|M.marinum_M               TICSFWLVSALVEIGEVAQAKRLCERLLSYASPLHLYAEEIEPRTGRHLG
MUL_3664|M.ulcerans_Agy99           TICSFWLVSALVEIGEVAQAKRLCERLLSYARPLHLYAEEIEPRTGRHLG
MAV_1780|M.avium_104                TICSFWLVSALVEIGEVRRAKRLCERLLSYASPLHLYAEEIEPRTGRQLG
MAB_1643|M.abscessus_ATCC_1997      TICSFWLVSALVEIGEVRRARHLCERLLSFASPLQLYAEEIDPATGRHLG
                                    ****************: :*::*******:* ** ******:* :**:**

TH_1448|M.thermoresistible__bu      NFPQAFTHLALINAVVHVIRAEEEADGSGEFIPANAPM
MSMEG_4535|M.smegmatis_MC2_155      NFPQAFTHLALINAVVHVIRAEEEADSSGVFVPANAPM
Mflv_2676|M.gilvum_PYR-GCK          NFPQAFTHLALINAVVHVIRAEEEADSSGVFQPANAPV
Mvan_3877|M.vanbaalenii_PYR-1       NFPQAFTHLALINAVVHVIRAEEEADSSGVFQPANAPV
Mb2425|M.bovis_AF2122/97            NFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM
Rv2402|M.tuberculosis_H37Rv         NFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM
MMAR_3721|M.marinum_M               NFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM
MUL_3664|M.ulcerans_Agy99           NFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM
MAV_1780|M.avium_104                NFPQAFTHLALINAVVHVIRAEEEADGSGMFQPANAPM
MAB_1643|M.abscessus_ATCC_1997      NFPQAFTHLALINAVVHVIRAEEEADVSGTFQPANAPT
                                    ************************** ** * *****