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M. thermoresistible (build 8) TH_1251 (-)

annotation: carboxylic ester hydrolase
coordinates: 2397093 - 2398580
length: 496

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1251--100% (496)carboxylic ester hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCK-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104MAV_5201-5e-0525.00% (324) putative acyltransferase
M. smegmatis MC2 155MSMEG_3303-0.064.96% (488) carboxylic ester hydrolase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


TH_1251|M.thermoresistible__bu      --------------------------------------------------
MSMEG_3303|M.smegmatis_MC2_155      --------------------------------------------------
MAV_5201|M.avium_104                MRRVGRLAIWDRPERRSGIPALDGLRAIAVALVLIGHGGIPGVSGGFIGV
                                                                                      

TH_1251|M.thermoresistible__bu      -------------------VRFGEILLC---------VVNAIGLAMLVLP
MSMEG_3303|M.smegmatis_MC2_155      --------------------------------------MLAAGLLALVLP
MAV_5201|M.avium_104                DVFFVLSGFLITSLLLDELGRTGRIELTGFWIRRARRLLPALVLMVLTVA
                                                                          : *  *  *.:.

TH_1251|M.thermoresistible__bu      LPAGARRARHLASAPALVALAQLIGEGYRWQLVPAYALAAGVT-------
MSMEG_3303|M.smegmatis_MC2_155      VPRGLR---LIATLPVPVAVAQLIFEGYRWQLIPAYVLAAAIG-------
MAV_5201|M.avium_104                AARQLLPERSLTGLRDDAIAAFLWMANWRFVAQKTDYFTQGAPPSPLQHT
                                     .        ::     .  * *   .:*:    :  :: .         

TH_1251|M.thermoresistible__bu      -----------LWWAVRVRR--PAPPTG-WRRLLGLTVGVVLLAAAVVVP
MSMEG_3303|M.smegmatis_MC2_155      -----------AWEVVSIGRGGRSSPRGRWLTVVTTLAAGVAFAVSVAIP
MAV_5201|M.avium_104                WSLGVEEQYYFVWPLLLIAVALALAARARRRCTRATVGGVRFSAFVIATV
                                                *  : :      .. .          .    *  :.  

TH_1251|M.thermoresistible__bu      VAVPVFRFPPPTGPYAIGTVTYHWRDDDRREIFDADPAARREIVAQVWYP
MSMEG_3303|M.smegmatis_MC2_155      VLVPVFRFPDPGGPYAIGTVSYHWRDHDRREIFDGDPAARRELMAQIWYP
MAV_5201|M.avium_104                GALASAAVAIVMAADGTRDRIYFGTDTRAQALLVG--AAAAALLVSDWPS
                                      :.   ..   .. .     *.  *   : :: .  **   ::.. * .

TH_1251|M.thermoresistible__bu      AEPGADAPVEPYVSDAATLAPAAG------------------RLLGVPGF
MSMEG_3303|M.smegmatis_MC2_155      AESSVEAETAPYVSDVDAFAPAAG------------------KLLGIPGF
MAV_5201|M.avium_104                MNRGWCMLRTRWARRVARILPVLGLAGLAAATHCASGASGEFRHGLLIGV
                                     : .       :.  .  : *. *                  :   : *.

TH_1251|M.thermoresistible__bu      VFSHLGVVPTHATRQPPLAPDRPRYPVLVFVSGLNG---FRQSNMFQVEQ
MSMEG_3303|M.smegmatis_MC2_155      VFSHFGKVRTHGVEAAPVASDRPRYPVLVFASGLNG---FRQSNMFQVEQ
MAV_5201|M.avium_104                AIAAVAVIAPVAVEQRGVVARVLALPPLVWLGTISYGVYLWHWPIFLALN
                                    .:: .. : . ...   :..     * **: . :.    : :  :* . :

TH_1251|M.thermoresistible__bu      LVSHGFVVVGLDQPYTSAVTVLADG--------------RAVDGWPKDRL
MSMEG_3303|M.smegmatis_MC2_155      LVSRGFVVVGIDQPHISAVTAFPDG--------------RRIPGWTKDRL
MAV_5201|M.avium_104                GERTGWAGMPLFAARCAATVAVAAASWWLLEQPIRRWRPARVPLLPLAAA
                                        *:. : :  .  :*..... .                :   .    

TH_1251|M.thermoresistible__bu      VDVIQQSITPVTPPPALGDVPLPAGLFPYLAADIGFALDRLGGLDADDPN
MSMEG_3303|M.smegmatis_MC2_155      VHVIQQSITPKEPAPAIGDTELPRGLFPYLAEDISFVLDELERLNDWDPS
MAV_5201|M.avium_104                TVASAAAVTLLVVPVGAGPGLREAGLPPGVSAVAAVSPSPPGNSRPRDPN
                                    . .   ::*    . . *      ** * ::   ..  .        **.

TH_1251|M.thermoresistible__bu      GLFTGRLDLDRAGAFGISLGAITVGQACHDDSRLRACLMMDAAMP--AEV
MSMEG_3303|M.smegmatis_MC2_155      GRFTGRLDIDRAGALGISLGAVTVGQVCHADPRLKACLMMDAAMP--ADV
MAV_5201|M.avium_104                RPFTVSVFGDSIGWTWMHYLPPTPGFAFLDHTVIGCSLVRGTPYRYIGET
                                      **  :  *  *   :   . * * .   .. : ..*: .:.    .:.

TH_1251|M.thermoresistible__bu      VRTG---------------LRRPAMWLTRDTESILAERDRNGGWP---DH
MSMEG_3303|M.smegmatis_MC2_155      VRDG---------------LEQPAMWLTRDADSILLERNRSGGWP---DH
MAV_5201|M.avium_104                LEQRPECDGWPIRWSRQVSQDQPDVALLIIGRWETVDRVNEGQWTHIGDP
                                    :.                   :* : *         :* ..* *.   * 

TH_1251|M.thermoresistible__bu      EVDETITTQRETFAGSAPGHGYHVEIPGMFHLNYTDAPRYTPLAQRLG--
MSMEG_3303|M.smegmatis_MC2_155      EIRETLDTQRAAFGKSKPGNGFYIETPGMFHLNYTDAPAWTPLAQALA--
MAV_5201|M.avium_104                TFDAYLNGELERALNIVGSTGVRVVVATVPYSRGGEKPDGRLYPEDQPDR
                                     .   :  :         . *  :  . : : .  : *     .:     

TH_1251|M.thermoresistible__bu      -------MSGPVGAERGHDIVARYTVAFFNRFLGEASDGDAALLDGP---
MSMEG_3303|M.smegmatis_MC2_155      -------LSGPIGAQRGHEILAAYTVAFFEHAL---DGGRPPLLDGP---
MAV_5201|M.avium_104                VNLWNTMLRKTVAHHPNVAILDLNKKLCPDGVYTAKVDGIKVRSDGVHLT
                                           :  .:. . .  *:   .    :       .*     **    

TH_1251|M.thermoresistible__bu      -------PPWPDVRIDRR
MSMEG_3303|M.smegmatis_MC2_155      -------PPWDEVAIERR
MAV_5201|M.avium_104                PEGVKWLTPWLEESLR--
                                           .** :  :