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M. thermoresistible (build 8) TH_0472 ()

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 1009290 - 1010261
length: 324

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0472-100% (324)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3119c-1e-11169.67% (300) integral membrane protein
M. gilvum PYR-GCKMflv_4415-1e-11874.67% (300) hypothetical protein Mflv_4415
M. tuberculosis H37RvRv3092c-1e-11170.00% (300) integral membrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_1567-1e-11367.88% (302) hypothetical protein MMAR_1567
M. avium 104-----
M. smegmatis MC2 155MSMEG_0562-1e-12374.17% (302) hypothetical protein MSMEG_0562
M. ulcerans Agy99MUL_3466-1e-10165.36% (280) hypothetical protein MUL_3466
M. vanbaalenii PYR-1Mvan_1939-1e-12376.00% (300) hypothetical protein Mvan_1939

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1567|M.marinum_M               MSAGLFGLLDDVAALARLAAASVDDVGSAAARATAKAAGVVVDDTAVTPQ
MUL_3466|M.ulcerans_Agy99           ----------------------MDDVGSAAARATAKAAGVVVDDTAVTPQ
Mb3119c|M.bovis_AF2122/97           MSGGLFGLLDHVAVLARLAAASIDDIGAAAGRATAKAAGVVIDDTAVTPQ
Rv3092c|M.tuberculosis_H37Rv        MSGGLFGLLDHVAVLARLAAASIDDIGAAAGRATAKAAGVVIDDTAVTPQ
Mflv_4415|M.gilvum_PYR-GCK          MSGGLFALLDDVAVLAKLAAASVDDIGAAAGRATAKAAGVVIDDTAVTPQ
Mvan_1939|M.vanbaalenii_PYR-1       MSGGLFALLDDVAMLARLAAASVDDIGAAAGKATAKAAGVVIDDTAVTPQ
MSMEG_0562|M.smegmatis_MC2_155      MSAGLFGLLDDVAALARLAAASVDDIGAAAGRATAKAAGVVIDDTAVTPQ
TH_0472|M.thermoresistible__bu      MSAGLFGLLDDVAALARMAAASVDDISAAAGRATAKAAGVVIDDTAVTPQ
                                                          :**:.:**.:*********:********

MMAR_1567|M.marinum_M               FVHGITAERELPIIKRIALGSLRNKLVFILPGAMLLSQFVPWLLSPILML
MUL_3466|M.ulcerans_Agy99           FVHGITAERELPIIKRIALGSLRNKLVFILPGAMLLSQFVPWLLSPILML
Mb3119c|M.bovis_AF2122/97           YVHRITAERELPIIKRIAIGSVRNKLLLILPGALLLSQLVPWLLTPLLML
Rv3092c|M.tuberculosis_H37Rv        YVHRITAERELPIIKRIAIGSVRNKLLLILPGALLLSQLVPWLLTPLLML
Mflv_4415|M.gilvum_PYR-GCK          YVHGIAAERELPIIKRIAKGSLRNKILIILPVALLLSQFVPWLLTPILML
Mvan_1939|M.vanbaalenii_PYR-1       YVHGIAAERELPIIKRIAIGSLRNKIVFILPAALLLSQFVPWLLTPILML
MSMEG_0562|M.smegmatis_MC2_155      YVHGITAERELPIIKKIAIGSIRNKIVFILPAILLLSQFVPVLLTPILMV
TH_0472|M.thermoresistible__bu      YVHGIAAERELPIIKRIAIGSVRNKLLFILPAALLLSQFLPWLLTPLLML
                                    :** *:*********:** **:***:::***  :****::* **:*:**:

MMAR_1567|M.marinum_M               GATYLCYEGAEKLWSALR---GNGSQARRPK-----DEQQVVTGAIRTDV
MUL_3466|M.ulcerans_Agy99           GATYLCYEGAEKLWSALR---GNGSQARRPK-----DEQQVVTGAMRTDV
Mb3119c|M.bovis_AF2122/97           GATYLCYEGAEKVCGVIG---GRGHDAAPQV-----AERELVAGAIRTDF
Rv3092c|M.tuberculosis_H37Rv        GATYLCYEGAEKVCGVIG---GRGHDAAPQV-----AERELVAGAIRTDF
Mflv_4415|M.gilvum_PYR-GCK          GATYLCFEGAEKVWGMIR---GHKSHGTLVAGSGEAAEKAMVAGAVRTDF
Mvan_1939|M.vanbaalenii_PYR-1       GATYLCYEGAEKVWGMIR---GHEKHGAPAAASGADAEKFMVTGAIRTDF
MSMEG_0562|M.smegmatis_MC2_155      GATYLCYEGAEKVWGWFPGHHGHDPHATPSAVTGADAEKSVVSGAIRTDL
TH_0472|M.thermoresistible__bu      GATYLCFEGAEKVWARIGPGDGHHHPAVPSSLVGPDAENQMASGAIRTDF
                                    ******:*****: . :    *.   .          *. :.:**:***.

MMAR_1567|M.marinum_M               ILSAEIMVIALSEVADLAFLPRLVVLIVVALVITGAVYGVVAAIVKMDDV
MUL_3466|M.ulcerans_Agy99           ILSAEIMVIALSEVADLAFLPRLVVLIVVALVITGAVYGVVAAIVKMDDV
Mb3119c|M.bovis_AF2122/97           ILSAEIMVIALNEVADQPFVPRLIVLVIVALVITAAVYGVVAVIVQMDDV
Rv3092c|M.tuberculosis_H37Rv        ILSAEIMVIALNEVADQPFVPRLIVLVIVALVITAAVYGVVAVIVQMDDV
Mflv_4415|M.gilvum_PYR-GCK          ILSAEIMVIALNEVADQSFLPRLIILLVVAVVITIAVYGVVAAIVKMDDI
Mvan_1939|M.vanbaalenii_PYR-1       ILSAEIMVIALNEVADQPFLPRLLILLVVAVVITAAVYGVVAGIVKMDDI
MSMEG_0562|M.smegmatis_MC2_155      ILSAEIMVIALNEVASEAFLPRLAILVVVAFVITAGVYGVVAAIVKMDDI
TH_0472|M.thermoresistible__bu      ILSAEIMVIALNEVAHQPFLPRLIILVVVALVITAAVYGVVALIVKMDDI
                                    ***********.***  .*:*** :*::**.*** .****** **:***:

MMAR_1567|M.marinum_M               GLRLAETSSRVGQRLGRALVAGTPRLLSMIAAVGTVAMLWVGGHILLVGS
MUL_3466|M.ulcerans_Agy99           GLRLAETSSRVGQRLGRALVAGTPRLLSMIAAVGTVAMLWVGGHILLVGS
Mb3119c|M.bovis_AF2122/97           GLRLTQTASRFGQRIGGGLVAGMPKLLSALSAVGMGAMLWVGGHMVLVGS
Rv3092c|M.tuberculosis_H37Rv        GLRLTQTASRFGQRIGGGLVAGMPKLLSALSAVGMGAMLWVGGHIVLVGS
Mflv_4415|M.gilvum_PYR-GCK          GLSLTQRSSGFAQKIGRGLVAGMPKLLSALSVIGTVAMLWVGGHILLIGA
Mvan_1939|M.vanbaalenii_PYR-1       GLSMTQRSSPFAHKIGHGLVAGMPKLLSALSVIGTVAMLWVGGHILLVGT
MSMEG_0562|M.smegmatis_MC2_155      GLHLAQRSSRIARKIGRGLVAGMPKLLSALATIGTVAMLWVGGHILLVGT
TH_0472|M.thermoresistible__bu      GLRLAQRATQATRRLGRSLVTAMPKVLAALSVIGTIAMLWVGGHILLLGT
                                    ** ::: ::   :::* .**:. *::*: ::.:*  ********::*:*:

MMAR_1567|M.marinum_M               DQIGWHTPYGLVHHLDEQVRHAVGSLGTVVAWLVNTGVSAALGLIVG-AV
MUL_3466|M.ulcerans_Agy99           DQIGWHTPYGLVHHLDEQVRHAVGSLGTVVAWLVNTGVSAALGLIVG-AV
Mb3119c|M.bovis_AF2122/97           DHLGWHAPYRLVHHLDD---HLVGSAGGALTWLVSTAACAATGLVIG-IV
Rv3092c|M.tuberculosis_H37Rv        DHLGWHAPYRLVHHLDD---HLVGSAGGALTWLVSTAACAATGLVIG-IV
Mflv_4415|M.gilvum_PYR-GCK          DELGWHAPYALVHHAEELVHH-VAGVGGVLGWLVNTAASAVIGLVVG-AI
Mvan_1939|M.vanbaalenii_PYR-1       DTLGWHLPYGLVHHAEEYVHH-VGGVGAVLAWLVNTAASAVIGLVVG-LI
MSMEG_0562|M.smegmatis_MC2_155      DTLGWHSPYGVVHHLEEAVHHAVPGVGAVLAWLVNTGISAVVGLVVG-AI
TH_0472|M.thermoresistible__bu      DTLGWHWPYGLIHSAEESVRAATGAFGGPLAWLVNTLASAVIGLTVGTAV
                                    * :*** ** ::*  ::     . . *  : ***.*  .*. ** :*  :

MMAR_1567|M.marinum_M               AVTLVHLLPFRRVG---------------
MUL_3466|M.ulcerans_Agy99           AVTLVHLLPFRRVG---------------
Mb3119c|M.bovis_AF2122/97           VVALVHLVCFRPPRSRSL-----------
Rv3092c|M.tuberculosis_H37Rv        VVALVHLVCFRPPRSRSL-----------
Mflv_4415|M.gilvum_PYR-GCK          VVAIVHALPFGKKVGKKNEAHG-------
Mvan_1939|M.vanbaalenii_PYR-1       VVAVMHVLPIGRK-----DKH--------
MSMEG_0562|M.smegmatis_MC2_155      VVLVMHLLPFGKKDAKKDAKKDDKGASHA
TH_0472|M.thermoresistible__bu      ALAQAGIRRLPGLNRRRGPETGG------
                                    .:       :