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M. thermoresistible (build 8) TH_0461 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 991726 - 992802
length: 359

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0461-100% (359)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3270c-4e-4261.54% (130) hypothetical protein Mb3270c
M. gilvum PYR-GCKMflv_4707-2e-3857.46% (134) hypothetical protein Mflv_4707
M. tuberculosis H37RvRv3242c-4e-4261.54% (130) hypothetical protein Rv3242c
M. leprae Br4923MLBr_00776-4e-1755.84% (77) hypothetical protein MLBr_00776
M. abscessus ATCC 19977MAB_3585c-8e-3155.66% (106) hypothetical protein MAB_3585c
M. marinum MMMAR_1303-2e-3867.92% (106) hypothetical protein MMAR_1303
M. avium 104MAV_4206-9e-4066.04% (106) hypothetical protein MAV_4206
M. smegmatis MC2 155MSMEG_1877-2e-4171.70% (106) hypothetical protein MSMEG_1877
M. ulcerans Agy99MUL_2578-3e-3867.92% (106) hypothetical protein MUL_2578
M. vanbaalenii PYR-1Mvan_1760-1e-3957.69% (130) hypothetical protein Mvan_1760

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4707|M.gilvum_PYR-GCK          -----MLDLILPKQCGGCGAVATGWCDACTDDLTVADDQPHLITPRLDPG
Mvan_1760|M.vanbaalenii_PYR-1       -----MLDLVLPLECGGCDAAATAWCPACARELTVKPDQPHLITPRLDPG
MSMEG_1877|M.smegmatis_MC2_155      -----MLDLVLPLACGGCGAASTRWCPRCAAELTVRDDEPHLVTPRTDPG
MAB_3585c|M.abscessus_ATCC_199      -----MLDLVLPLMCGGCGSPSVRWCDDCACAFST---QPAVVSTRVDPG
Mb3270c|M.bovis_AF2122/97           -----MLDLVLPLECGGCGAPATRWCAACAAELSVAAGEPHVVSPRVDPQ
Rv3242c|M.tuberculosis_H37Rv        -----MLDLVLPLECGGCGAPATRWCAACAAELSVAAGEPHVVSPRVDPQ
MMAR_1303|M.marinum_M               -----MLDLVLPLECGGCGAPSTRWCAACATELAVAATHPHVVSPRADPQ
MUL_2578|M.ulcerans_Agy99           -----MLDLVLPLECGGCGAPSTRWCAACATELAVAATRPHVVSPRADPQ
MAV_4206|M.avium_104                -----MLDLFLPAECGGCAAPATRWCPACAAELVVKPDEPHVVNPRVDPG
MLBr_00776|M.leprae_Br4923          --------------MAGCGVFATRWSDACTAELSVAAGEPRVVSLCVDPL
TH_0461|M.thermoresistible__bu      VLDGPVLDLVLPLHCGGCGAPATRWCPACARELFLRADDPRLVTPRLDPG
                                                   .**   :. *.  *:  :      * ::.   ** 

Mflv_4707|M.gilvum_PYR-GCK          VPVLSLGRYAGARRNAIVAVKEHGRTDLRRPLADALRAGLDHLLTWGVLA
Mvan_1760|M.vanbaalenii_PYR-1       VPVLSLGRYAGPRRKAIVALKEHGRTDLQQPLAAALAEALDHLLTWGVLD
MSMEG_1877|M.smegmatis_MC2_155      VPVFALGRYAGARRRAIVAAKEHGRADLLPPLANALRSGLERLLTWGVVV
MAB_3585c|M.abscessus_ATCC_199      VPVLSLGRYAGVRRQAIVTMKERGRRDLAAPLGVVLARGVDQLLRWNLIE
Mb3270c|M.bovis_AF2122/97           VPVFALGRYAGVRRQAILAMKEHGRRDLVAPLACALIVGVDHLLSWGMLE
Rv3242c|M.tuberculosis_H37Rv        VPVFALGRYAGVRRQAILAMKEHGRRDLVAPLACALIVGVDHLLSWGMLE
MMAR_1303|M.marinum_M               VPVFALGRYAGARRHAILALKERGRGDLVAPLARALAVGVHRLLCWGIVG
MUL_2578|M.ulcerans_Agy99           VPVFALGRYAGARRYAILALKERGRGDLVAPLARALAVGVHRLLCWGIVG
MAV_4206|M.avium_104                VPVFALGRYANTRRRALLALKEHGRADLVAPLAGALAVAVHRLLGWGIVA
MLBr_00776|M.leprae_Br4923          VPVVVLGRYVGARRQAILAMKEHGRR------------------------
TH_0461|M.thermoresistible__bu      VPVFTLGRYTGARRSAIVAVKEHGRADLLAPLAGAVRQGISRLFQWGLLE
                                    ***. ****.. ** *::: **:**                         

Mflv_4707|M.gilvum_PYR-GCK          APLTLVPAPTR---------------------------------------
Mvan_1760|M.vanbaalenii_PYR-1       VPVTLVPAPTR---------------------------------------
MSMEG_1877|M.smegmatis_MC2_155      APVIVVPAPTR---------------------------------------
MAB_3585c|M.abscessus_ATCC_199      RPVTLVPAPTR---------------------------------------
Mb3270c|M.bovis_AF2122/97           NPLTMVPAPTR---------------------------------------
Rv3242c|M.tuberculosis_H37Rv        NPLTMVPAPTR---------------------------------------
MMAR_1303|M.marinum_M               TPLTLVPAPTR---------------------------------------
MUL_2578|M.ulcerans_Agy99           TPLTLVPAPTR---------------------------------------
MAV_4206|M.avium_104                TPLIVVPAPTR---------------------------------------
MLBr_00776|M.leprae_Br4923          ---NLVALPTR---------------------------------------
TH_0461|M.thermoresistible__bu      TPLTVVPAPTRAWAGXXIRQCAGGGLPQRHGRVLGERGPLRVHLDDRFAL
                                        :*. ***                                       

Mflv_4707|M.gilvum_PYR-GCK          ---------RTAARRRGGDPVT-----------------HIA-TQAARPP
Mvan_1760|M.vanbaalenii_PYR-1       ---------RMSARRRGGDPVT-----------------RIARTAAAGLP
MSMEG_1877|M.smegmatis_MC2_155      ---------RSAARRRGGDPVT-----------------RVAVAATAALP
MAB_3585c|M.abscessus_ATCC_199      ---------WTAARGRGGDPVT-----------------AVA-AVAARMP
Mb3270c|M.bovis_AF2122/97           ---------RWAARRRGGDPVSRM--------------ARIAGATLGRHH
Rv3242c|M.tuberculosis_H37Rv        ---------RWAARRRGGDPVSRM--------------ARIAGATLGRHH
MMAR_1303|M.marinum_M               ---------RAAARRRGGDPIT-----------------RIADAAVAAHP
MUL_2578|M.ulcerans_Agy99           ---------RAAARRRGGDPIT-----------------RIADAAVAAHP
MAV_4206|M.avium_104                ---------LSAARRRGGDPIT-----------------RLARAAVARHP
MLBr_00776|M.leprae_Br4923          ---------QCVSR------------------------------------
TH_0461|M.thermoresistible__bu      RERELGQTGRRVDDRRGPDHDHHVGVHHRTDRTLPDVLGQVLAEPHHIGA
                                                                                      

Mflv_4707|M.gilvum_PYR-GCK          DQSVATVLRFRAFTRDSVGLSSAARQRNVAGRVVLT-----RPVAG----
Mvan_1760|M.vanbaalenii_PYR-1       GVAVAPVLRFKAFTRDSVGLSLAARQRNVTGRVRLAGR-VANPISD----
MSMEG_1877|M.smegmatis_MC2_155      GVTTVPALRTRAWVRDSVGLSGGDRQRNLAGRIRLTRA-GRRALSDGAEG
MAB_3585c|M.abscessus_ATCC_199      GVHIASLLRMKMGARDSVGLSAAARQHNVAGRIALRR--TARPATE----
Mb3270c|M.bovis_AF2122/97           DVTVVPALRMRALARDSVGLGASARERNITGRVLLR---GQRPRNE----
Rv3242c|M.tuberculosis_H37Rv        DVTVVPALRMRALARDSVGLGASARERNITGRVLLR---GQRPRNE----
MMAR_1303|M.marinum_M               DIAVVQALRMRALARDSVGLGSSARERNAAGRVLMLK--GQRLGTE----
MUL_2578|M.ulcerans_Agy99           DIAVVQALRMRALARDSVGLGSSARERNAAGRVLMLK--GQRLGTE----
MAV_4206|M.avium_104                DIAVAPMLRIRALTRDSVGLGTAERERNIAGRVVLRGRPAPLPGAD----
MLBr_00776|M.leprae_Br4923          -------------------LGSCT----LPGRG-----------------
TH_0461|M.thermoresistible__bu      NQPAAEAIRGIHRLHRFGHLGQVAFERGAAGVAVEFEQAAVHVVHAAAAG
                                                       *.        .*                   

Mflv_4707|M.gilvum_PYR-GCK          PVVVVDDVV----TTGATVTESVRVLQTAGIDVVAVLALANA--------
Mvan_1760|M.vanbaalenii_PYR-1       PVVVVDDVV----TTGATATESVRVLQTSGAHVVAVLALANA--------
MSMEG_1877|M.smegmatis_MC2_155      DLVLVDDVV----TTGATATESVRTLARSGAEVAVMLAISHA--------
MAB_3585c|M.abscessus_ATCC_199      -LMLVDDVV----TTGATVAESVRVLKSAGFRVAAALTLTHS--------
Mb3270c|M.bovis_AF2122/97           -VVLVDDII----TTGATARESVRVLQAAGVRVGAVLAVAAA--------
Rv3242c|M.tuberculosis_H37Rv        -VVLVDDII----TTGATARESVRVLQAAGVRVGAVLAVAAA--------
MMAR_1303|M.marinum_M               -IVVVDDVV----TTGATVRESVRVLRAAGVRVAAVLTIAAA--------
MUL_2578|M.ulcerans_Agy99           -IVVVDDVV----TTGATVRESVRVLRAAGVRVAAVLTIAAA--------
MAV_4206|M.avium_104                -VLVVDDVV----TTGATARESVRVLHAAGARVAAVLAIAAA--------
MLBr_00776|M.leprae_Br4923          --------------------------------------------------
TH_0461|M.thermoresistible__bu      PLVQVVDVLGDDVDVGVVLPGGYRAVAVIGLHLRHHVVPPQVPRPHLLRL
                                                                                      

Mflv_4707|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1760|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_1877|M.smegmatis_MC2_155      --------------------------------------------------
MAB_3585c|M.abscessus_ATCC_199      --------------------------------------------------
Mb3270c|M.bovis_AF2122/97           --------------------------------------------------
Rv3242c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1303|M.marinum_M               --------------------------------------------------
MUL_2578|M.ulcerans_Agy99           --------------------------------------------------
MAV_4206|M.avium_104                --------------------------------------------------
MLBr_00776|M.leprae_Br4923          --------------------------------------------------
TH_0461|M.thermoresistible__bu      LPPPLRTGDLVGVDFRPQPRLDIAEGRHAALRRHAGPGDHSYSHTTNVAV
                                                                                      

Mflv_4707|M.gilvum_PYR-GCK          --------
Mvan_1760|M.vanbaalenii_PYR-1       --------
MSMEG_1877|M.smegmatis_MC2_155      --------
MAB_3585c|M.abscessus_ATCC_199      --------
Mb3270c|M.bovis_AF2122/97           --------
Rv3242c|M.tuberculosis_H37Rv        --------
MMAR_1303|M.marinum_M               --------
MUL_2578|M.ulcerans_Agy99           --------
MAV_4206|M.avium_104                --------
MLBr_00776|M.leprae_Br4923          --------
TH_0461|M.thermoresistible__bu      LGNTGRRG