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M. thermoresistible (build 8) TH_0449 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 975856 - 976710
length: 285

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0449-100% (285)CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3230c-1e-14283.45% (284) hypothetical protein Mb3230c
M. gilvum PYR-GCKMflv_4669-1e-15289.44% (284) hypothetical protein Mflv_4669
M. tuberculosis H37RvRv3205c-1e-14283.45% (284) hypothetical protein Rv3205c
M. leprae Br4923MLBr_00818-1e-14183.45% (284) hypothetical protein MLBr_00818
M. abscessus ATCC 19977MAB_3524c-1e-14987.32% (284) hypothetical protein MAB_3524c
M. marinum MMMAR_1353-1e-14081.34% (284) hypothetical protein MMAR_1353
M. avium 104MAV_4151-1e-14785.92% (284) hypothetical protein MAV_4151
M. smegmatis MC2 155MSMEG_1938-1e-15591.90% (284) hypothetical protein MSMEG_1938
M. ulcerans Agy99MUL_2526-1e-13981.34% (284) hypothetical protein MUL_2526
M. vanbaalenii PYR-1Mvan_1798-1e-15490.49% (284) hypothetical protein Mvan_1798

CLUSTAL 2.0.9 multiple sequence alignment


Mb3230c|M.bovis_AF2122/97           ------------MGSTRLTGVNVEPPPEHVLVAFGLAGAQPILLGAGWEG
Rv3205c|M.tuberculosis_H37Rv        ------------MGSTRLTGVNVEPPPEHVLVAFGLAGAQPILLGAGWEG
MLBr_00818|M.leprae_Br4923          -------MRSPRSGSTRLTRVTVEPPPEHVLSAFGLTGVQPVPLGASWEG
MAV_4151|M.avium_104                --------------------MTVEPPPDHVLSAFGLAGVKPVYLGASWEG
Mflv_4669|M.gilvum_PYR-GCK          ------------------MAVTAERPPEHVLAAFGLSGVQPAPLGSSWEG
Mvan_1798|M.vanbaalenii_PYR-1       ------------------MAVTAERPPEHVLAAFGLSGVQPAPLGSSWEG
MSMEG_1938|M.smegmatis_MC2_155      --------------------MSVERPPEHVLAAFGLSGVRPVPLGSSWEG
TH_0449|M.thermoresistible__bu      --------------------MTVERPPEHVLAAFGLAGVRPVPLGSEWEG
MAB_3524c|M.abscessus_ATCC_199      --------------------MTVDRPPEHVLATYGLSGVKPVQLGPTWEG
MMAR_1353|M.marinum_M               --------------------MSVEPPPEHVLAAFGLTGVEPASLGASWEG
MUL_2526|M.ulcerans_Agy99           MSSKPDTGPAPRGASTRLTAVSVEPPPEHVLAAFGLTGVEPASLGASWEG
                                                        :..: **:*** ::**:*..*  **. ***

Mb3230c|M.bovis_AF2122/97           GWRCGEVVLSMVADNARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSG
Rv3205c|M.tuberculosis_H37Rv        GWRCGEVVLSMVADNARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSG
MLBr_00818|M.leprae_Br4923          GWRCGEVVLSMVADNARAAWSARVRETLFVDGIRLARPVRSTDGRYVVSC
MAV_4151|M.avium_104                GWRCGEVVLSLVADNARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSG
Mflv_4669|M.gilvum_PYR-GCK          GWRCGEVVLSMVADHARAAWSAKVRETLFVDGVRLARPVRSTDGRYVVAG
Mvan_1798|M.vanbaalenii_PYR-1       GWRCGEVVLSMVADHARAAWSAKVRETLFVDGVRLARPVRSTDGRYVVAG
MSMEG_1938|M.smegmatis_MC2_155      GWRCGEVVMSMVADHARAAWSAKVRETLFVDGVRLARPVRSTDGRYVVAG
TH_0449|M.thermoresistible__bu      GWRCGEVVLSMVADHARAAWSAKVRETLFVDGVRLARPVRSTDGRYVVAG
MAB_3524c|M.abscessus_ATCC_199      GWRCGEVVLSLVADHARAAWSAKVRDTLFVDGVRLARPVRSTDGRYVVSG
MMAR_1353|M.marinum_M               GWRCGEVVLSMVAENARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSG
MUL_2526|M.ulcerans_Agy99           GWRCGEVVLSMVAENARAAWSARVRETLFVDGVRLARPVRSTDGRYVVSG
                                    ********:*:**::*******:**:******:***************: 

Mb3230c|M.bovis_AF2122/97           WRADTFVAGAPEPRHDEVVSAAVRLHEATGKLERPRFLTQGPAAPWAEID
Rv3205c|M.tuberculosis_H37Rv        WRADTFVAGAPEPRHDEVVSAAVRLHEATGKLERPRFLTQGPAAPWAEID
MLBr_00818|M.leprae_Br4923          WRANTFVAGTPEARHDEVVSAAVRLHEATGKLERPRFLTQGPTARWADVD
MAV_4151|M.avium_104                WRADTFVAGTPEPRHDEVVSAAVRLHEATGKLERPRFLTQGPTAPWGDVD
Mflv_4669|M.gilvum_PYR-GCK          WRADTYVAGTPEPRHDEVVSAAVRLHEAMAKLERPRFLTQPPIAPWGDVD
Mvan_1798|M.vanbaalenii_PYR-1       WRADTYVAGMPEPRHDEVVSAAVRLHEATAKLERPRFLTQPPIAPWGDVD
MSMEG_1938|M.smegmatis_MC2_155      WRADTFVAGTPEPRHDEVVSAAVRLHEATAKLERPRFLTQPPVAPWADVD
TH_0449|M.thermoresistible__bu      WRADTFVAGVPEPRHDEVVSAGVRLHEATAKLERPRFLTQPPIAPWGDVD
MAB_3524c|M.abscessus_ATCC_199      WRADTFVAGAPEPRHDEVVSLSVRLHEATSKLERPRFLTQPPVAPWADVD
MMAR_1353|M.marinum_M               WRADTFVAGTPEPRHDEVVSAAVRLHEATSKLERPRFLTQGPATPWAEVD
MUL_2526|M.ulcerans_Agy99           WRADTFVAGTPEPRHDEVVSAAVRLHEATSKLERPRFLTQGPATPWAEVD
                                    ***:*:*** **.******* .****** .********** * : *.::*

Mb3230c|M.bovis_AF2122/97           VFVAADRAGWEERPLQSVPPGVPTAPPAADPQRSIDLINQLAGLRKPTKS
Rv3205c|M.tuberculosis_H37Rv        VFVAADRAGWEERPLQSVPPGVPTAPPAADPQRSIDLINQLAGLRKPTKS
MLBr_00818|M.leprae_Br4923          IFIAADRAAWEGRPLQSVPSGVWAAPMTTDGQRSVDLINQLAGLRKPTRS
MAV_4151|M.avium_104                IFIAADRAAWEERPLASVPPGARVAPATADAQRSVDLLNQLATLRKPTKS
Mflv_4669|M.gilvum_PYR-GCK          VFIAADRAAWEERPLHSLPPGARVGPGAADGQKSIELLNQLATLRRPTKS
Mvan_1798|M.vanbaalenii_PYR-1       VFIAADRAAWEDRPLHSLPPGARVAPGTSDGQKSIELINQLATLRRPTKS
MSMEG_1938|M.smegmatis_MC2_155      VFIAADRAAWEERPLHSLPQGARVAPGSADGQKSIELINQLATLRKPTKS
TH_0449|M.thermoresistible__bu      VFIAADRAAWEERPLHSLPPEARVAPGSADGQRSIELINQLASLRRPTRS
MAB_3524c|M.abscessus_ATCC_199      VFIAADRAAWEDRPLQSWPSAARVSPGSPDGQRSIDLINQLASLRRPTKS
MMAR_1353|M.marinum_M               VFIVADRAAWEERPLQSIPPGARPTQMTEDAEQSIELVNHLATLRKPTRS
MUL_2526|M.ulcerans_Agy99           VFIVADRAAWEERPLQSIPPGARPTQMTEDAEQSIELVNHLATLRKPTRS
                                    :*:.****.** *** * *  .     : * ::*::*:*:** **:**:*

Mb3230c|M.bovis_AF2122/97           PNQLVHGDLYGTVLFAGTAPPGITDITPYWRPASWAAGVAVVDALSWGAA
Rv3205c|M.tuberculosis_H37Rv        PNQLVHGDLYGTVLFAGTAPPGITDITPYWRPASWAAGVAVVDALSWGAA
MLBr_00818|M.leprae_Br4923          PNQLVHGDLYGTMLFVGTAAPGITDITPYWRPASWAAGVVVVDALSWGEA
MAV_4151|M.avium_104                PNQLVHGDLYGTVLFVGSAAPGITDITPYWRPASWAAGVVVIDALSWGEA
Mflv_4669|M.gilvum_PYR-GCK          PSQVVHGDLYGTVLFAGTAAPGITDITPYWRPPAWAAGVVVVDALSWGEA
Mvan_1798|M.vanbaalenii_PYR-1       PSQLVHGDLYGTVLFAGTAAPGITDITPYWRPPAWAAGVVVVDALAWGEA
MSMEG_1938|M.smegmatis_MC2_155      ASQLVHGDLYGTVLFAGAAAPGITDITPYWRPASWAAGVVVVDALSWGDA
TH_0449|M.thermoresistible__bu      PSQVVHGDLYGTVLFAGAAAPGITDITPYWRPASWAAGVAVVDALSWGEA
MAB_3524c|M.abscessus_ATCC_199      PPQLVHGDLYGTVLFAGAAAPGITDITPYWRPASWAAGVAVVDALSWGDA
MMAR_1353|M.marinum_M               PNQVVHGDLYGTVLFAGTAPPGITDITPYWRPASWAAGVVVIDALAWGDA
MUL_2526|M.ulcerans_Agy99           PNQVVHGDLYGTVLFAGTAPPGITDITPYWRPASWAAGVVVIDALAWGGA
                                    . *:********:**.*:*.************.:*****.*:***:** *

Mb3230c|M.bovis_AF2122/97           DDGLIERWNALPEWPQMLLRALMFRLAVYALHPRSTAEAFPGLAHTAALV
Rv3205c|M.tuberculosis_H37Rv        DDGLIERWNALPEWPQMLLRALMFRLAVYALHPRSTAEAFPGLAHTAALV
MLBr_00818|M.leprae_Br4923          DDGLIERWNALPEWPQMLLRALMFRLAVHALHPRSTAEAFPGLARTAALV
MAV_4151|M.avium_104                DDGLIERWNALPEWPQMLLRALMFRLAVHALHPRSTAEAFPGLARTAALV
Mflv_4669|M.gilvum_PYR-GCK          DDALIERWAQLPEWPQMLLRALMFRLAVHALHPRSTAAAFPGLARSASLI
Mvan_1798|M.vanbaalenii_PYR-1       DDALIERWSALPEWPQMLLRALMFRLAVHALHPRSTAAAFPGLARTAALV
MSMEG_1938|M.smegmatis_MC2_155      DDGLIERWDSLPEWPQMLLRALMFRLAVHALHPRSTAAAFPGLARTASLV
TH_0449|M.thermoresistible__bu      DDGLIERWSSLPEWPQMLLRALIFRLAVHALHPRSTAEAFPGLARTAALV
MAB_3524c|M.abscessus_ATCC_199      DDGLIERWATLPEWPQMLLRALIFRLAVHALHPRSSAQSFPGLARTAALV
MMAR_1353|M.marinum_M               DDGLIERWGALPEWPQMLLRALMFRLAVHALHPRSTSEAFPGLARTAGLI
MUL_2526|M.ulcerans_Agy99           DDGLIERWGALPEWPQMLLRALMFRLAVHALHPRSTSEAFPGLARTAGLI
                                    **.*****  ************:*****:******:: :*****::*.*:

Mb3230c|M.bovis_AF2122/97           RLVL
Rv3205c|M.tuberculosis_H37Rv        RLVL
MLBr_00818|M.leprae_Br4923          RLVL
MAV_4151|M.avium_104                RLVL
Mflv_4669|M.gilvum_PYR-GCK          RLTL
Mvan_1798|M.vanbaalenii_PYR-1       RLTL
MSMEG_1938|M.smegmatis_MC2_155      RLIL
TH_0449|M.thermoresistible__bu      RLIL
MAB_3524c|M.abscessus_ATCC_199      RLTL
MMAR_1353|M.marinum_M               RMLL
MUL_2526|M.ulcerans_Agy99           RMLL
                                    *: *