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M. tuberculosis H37Rv Rv3848 (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 4322326 - 4323234
length: 302

MLAATLLSLGAVFLAELGDRSQLITMTYTLRYRWWVVLTGVAIAAFTVHGVAVAIGHFLGSTVPARPAAC
VSAIAFLIFAVWVWREDTASDSETSPTAAEPRLALFTVVSSFALAELGDKTTLATVTLASDHHWAGVWIG
TTLGMILADGLAIGAGLLLHRRLPERLLQVLTGLLFLLFGLWLLFDDALGFRSVAIAVTAAVVLAAATTA
VSVRVAQTRRRRPTAAATPEDDSTRPERSSVAPGHPGSILLPLPEVSLRGRRPPSGSPDERCADPGSKGG
SRRISVGCWLPGVGRIRPTRSS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3848--100% (302)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3878-1e-17199.67% (302) transmembrane protein
M. gilvum PYR-GCKMflv_2016-3e-5646.41% (237) hypothetical protein Mflv_2016
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_5398-6e-8974.24% (229) hypothetical protein MMAR_5398
M. avium 104-----
M. smegmatis MC2 155MSMEG_5329-3e-5645.76% (236) hypothetical protein MSMEG_5329
M. thermoresistible (build 8)TH_0752-5e-7459.91% (232) PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. ulcerans Agy99MUL_5020-6e-8974.24% (229) hypothetical protein MUL_5020
M. vanbaalenii PYR-1Mvan_4708-2e-5545.27% (243) hypothetical protein Mvan_4708

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2016|M.gilvum_PYR-GCK          MLAALLLSFAVIFVAELGDKTQLVAMMFALRYRWWVVLSAITVATTAVHV
Mvan_4708|M.vanbaalenii_PYR-1       MLAALLLSFAVIFVAELGDKTQLVAMMFALRYRWWVVLSAITAATAVVHV
MSMEG_5329|M.smegmatis_MC2_155      MLAALALSFGVIFIAELGDKSQLMAMTFALRYRWWVVLGGITLATTAVHL
Rv3848|M.tuberculosis_H37Rv         MLAATLLSLGAVFLAELGDRSQLITMTYTLRYRWWVVLTGVAIAAFTVHG
Mb3878|M.bovis_AF2122/97            MLAATLLSLGAVFLAELGDRSQLITMTYTLRYRWWVVLTGVAIAAFTVHG
MMAR_5398|M.marinum_M               MLSATMLSLGVVFLAELGDRSQLITMTYALRYRWWVVLTGVAIASVTVHG
MUL_5020|M.ulcerans_Agy99           MLSATMLSLGVVFLAELGDRSQLITMTYALRYRWWVVLTGVAIASVTVHG
TH_0752|M.thermoresistible__bu      MLTATLISLGVVFVAELGDKSQLITMTYALRHRWWVVLSGVGIAALLVHG
                                    **:*  :*:..:*:*****::**::* ::**:****** .:  *:  ** 

Mflv_2016|M.gilvum_PYR-GCK          LSVAIGHYLGAALPTHLLGLIAGAMFIFFGLWTLRGDSLS--DEEASRAE
Mvan_4708|M.vanbaalenii_PYR-1       LSVAIGYYLGAALPTHLLGFIAGAMFIFFGLWTLRGDSLT--DEETSRAA
MSMEG_5329|M.smegmatis_MC2_155      ISVAVGHYLGAALPTHLLGIVAGVAFVFFGLWTLRGDRLS--EDEATRAQ
Rv3848|M.tuberculosis_H37Rv         VAVAIGHFLGSTVPARPAACVSAIAFLIFAVWVWREDTAS--DSETSPTA
Mb3878|M.bovis_AF2122/97            VAVAIGHFLGSTVPARPAACVSAIAFLIFAVWVWREDTAS--DSETSPTA
MMAR_5398|M.marinum_M               VSVAVGHFLGTTVPARPMAFVGAIAFLIFAGWAWREGREDPAGADEVAHL
MUL_5020|M.ulcerans_Agy99           VSVAVGHFLGTTVPARPMAFVGAIAFLIFAGWAWREGREDPAGADGVAHL
TH_0752|M.thermoresistible__bu      ISVAVGHFLGMTLPERPIAFAAAVAFLLFAAWTWWDGRDP--GGDGAPSV
                                    ::**:*::** ::* :  .  ..  *::*. *.   .       :     

Mflv_2016|M.gilvum_PYR-GCK          KATAPAFFVVTSAFVLAELGDKTMLATVTLASDNDWLGVWIGSTLGMVAA
Mvan_4708|M.vanbaalenii_PYR-1       KATAPAFFVVTSAFVLAELGDKTMLATVTLAADRDWLGVWIGSTLGMVAA
MSMEG_5329|M.smegmatis_MC2_155      RTSAPAFFAVTSAFLLAELGDKTMLATITLAADNDWVGVWIGSTIGMVAA
Rv3848|M.tuberculosis_H37Rv         AEPRLALFTVVSSFALAELGDKTTLATVTLASDHHWAGVWIGTTLGMILA
Mb3878|M.bovis_AF2122/97            AEPRLALFTVVSSFALAELGDKTTLATVTLASDHHWAGVWIGTTLGMILA
MMAR_5398|M.marinum_M               PNPRFALLTVVSSFVLAELSDKTTLATVTLASDHNWAGVWIGTTLGMIVA
MUL_5020|M.ulcerans_Agy99           PSPRFALLTVVSSFVLAELSDKTTLATVTLASDHNWAGVWIGTTLGMIVA
TH_0752|M.thermoresistible__bu      AQTRHVLFAVVSSFVLAELGDKTMLATVALASEHAWAGVWIGATAGMVLA
                                      .  .::.*.*:* ****.*** ***::**::. * *****:* **: *

Mflv_2016|M.gilvum_PYR-GCK          DGLAIIVGAVLGRRLPERVIQIAAAALFLLFGAYMLLENIFPSLPFALVG
Mvan_4708|M.vanbaalenii_PYR-1       DGLAILVGAVAGKHLPERLIQISAAALFLLFGFYMVFDNLLPTAPTAAVA
MSMEG_5329|M.smegmatis_MC2_155      DALAIVVGAIAGKHLPERMIQIAAAVLFLGFGFFMLLENIWHAPALLLVA
Rv3848|M.tuberculosis_H37Rv         DGLAIGAGLLLHRRLPERLLQVLTGLLFLLFGLWLLFDDALGFRSVAIAV
Mb3878|M.bovis_AF2122/97            DGLAIGAGLLLHRRLPERLLQVLTGLLFLLFGLWLLFDDALGFRSIAIAV
MMAR_5398|M.marinum_M               DGLAIGVGLLLHHRLPEQLLHLLASLLFLLFGLWMLFEGALGWRSVAIGV
MUL_5020|M.ulcerans_Agy99           DGLAIGVGLLLHHRLPEQLLHLLASLLFLLFGLWMLFEGALGWRSVAIGV
TH_0752|M.thermoresistible__bu      DGVAIAVGAVLNRRLPIRSLHRLAGLLFLVVGLWLLFDAALGWRGVAVAA
                                    *.:** .* :  ::** : ::  :. *** .* :::::            

Mflv_2016|M.gilvum_PYR-GCK          GIALTIVAASGAAVWALPERLRPA-------------VLRP-APAAE---
Mvan_4708|M.vanbaalenii_PYR-1       GAALTLVLILGGVMRALPDRLRPA-------------VLRPSAPSAVDIA
MSMEG_5329|M.smegmatis_MC2_155      -ASLGIVAALAAMVFALPERLRPQ-------------VLRRSSAAAD---
Rv3848|M.tuberculosis_H37Rv         TAAVVLAAATTAVSVRVAQTRRRRPTAAATPEDDSTRPERSSVAPGHPGS
Mb3878|M.bovis_AF2122/97            TAAVVLAAATTAVSVRVAQTRRRRPTAAATPEDDSTRPERSSVAPGHPGS
MMAR_5398|M.marinum_M               TAAVALAAAAGAT----AQTLRRR---------------RSASALGTN--
MUL_5020|M.ulcerans_Agy99           TAAVALAAAAGAT----AQTLRRR---------------RSASALGTS--
TH_0752|M.thermoresistible__bu      VGGAVALAGLAAT----VGYLRGR--------------AAPEPAPITP--
                                      .        .         *                     .      

Mflv_2016|M.gilvum_PYR-GCK          ----------QDGTASTDTASADTTSTDTTSTDTK---------------
Mvan_4708|M.vanbaalenii_PYR-1       ----------ERDECSPDAAIGSGAGRSAAPSDGRD--------------
MSMEG_5329|M.smegmatis_MC2_155      --------------TEEDTGLREPAQREV---------------------
Rv3848|M.tuberculosis_H37Rv         ILLPLPEVSLRGRRPPSGSPDERCADPGSKGGSRRISVGCWLPGVGRIRP
Mb3878|M.bovis_AF2122/97            ILLPLPEVSLRGRRPPSGSPDERCADPGSKGGSRRISVGCWLPGVGRIRP
MMAR_5398|M.marinum_M               --------------SPSGR-------------------------------
MUL_5020|M.ulcerans_Agy99           --------------SPSGR-------------------------------
TH_0752|M.thermoresistible__bu      ---------------TQDR-------------------------------
                                                     .                                

Mflv_2016|M.gilvum_PYR-GCK          ----
Mvan_4708|M.vanbaalenii_PYR-1       ----
MSMEG_5329|M.smegmatis_MC2_155      ----
Rv3848|M.tuberculosis_H37Rv         TRSS
Mb3878|M.bovis_AF2122/97            TRSS
MMAR_5398|M.marinum_M               ----
MUL_5020|M.ulcerans_Agy99           ----
TH_0752|M.thermoresistible__bu      ----