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M. tuberculosis H37Rv Rv3809c (glf)

annotation: UDP-GALACTOPYRANOSE MUTASE GLF (UDP-GALP MUTASE) (NAD+-FLAVIN ADENINE DINUCLEOTIDE-REQUIRING ENZYME)
coordinates: 4272276 - 4273475
length: 399

QPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSN
KRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQAAEIDTADAQNL
EEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITRLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNM
AADHRIEVRLNTDWFDVRGQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVM
NYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETA
SSKVLFGGRLGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3809cglf-100% (399)UDP-GALACTOPYRANOSE MUTASE GLF (UDP-GALP MUTASE) (NAD+-FLAVIN ADENINE DINUCLEOTIDE-REQUIRING ENZYME)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3839cglf0.0100.00% (399) UDP-galactopyranose mutase Glf
M. gilvum PYR-GCKMflv_1159-0.088.07% (394) UDP-galactopyranose mutase
M. leprae Br4923MLBr_00092glf0.086.62% (396) putative UDP-galactopyranose mutase
M. abscessus ATCC 19977MAB_0170-0.087.11% (388) UDP-galactopyranose mutase (Glf)
M. marinum MMMAR_5373glf0.091.92% (396) UDP-galactopyranose mutase Glf
M. avium 104MAV_0208glf0.093.64% (393) UDP-galactopyranose mutase
M. smegmatis MC2 155MSMEG_6404glf0.085.75% (393) UDP-galactopyranose mutase
M. thermoresistible (build 8)TH_2083glf0.086.87% (396) UDP-GALACTOPYRANOSE MUTASE GLF (UDP-GALP MUTASE) (NAD+-FLAVIN
M. ulcerans Agy99MUL_4993glf0.091.67% (396) UDP-galactopyranose mutase Glf
M. vanbaalenii PYR-1Mvan_5650-0.088.30% (393) UDP-galactopyranose mutase

CLUSTAL 2.0.9 multiple sequence alignment


Rv3809c|M.tuberculosis_H37Rv        ---------------------MQPMTARFDLFVVGSGFFGLTIAERVATQ
Mb3839c|M.bovis_AF2122/97           ---------------------MQPMTARFDLFVVGSGFFGLTIAERVATQ
MAV_0208|M.avium_104                ------------------------MTARFDLFVVGSGFFGLTIAERVATQ
MMAR_5373|M.marinum_M               ------------------------MTARFDLFVVGSGFFGLTIAERVATQ
MUL_4993|M.ulcerans_Agy99           ------------------------MTARFDLFVVGSGFFGLTIAERVATQ
MLBr_00092|M.leprae_Br4923          ------------------------MTVSFDLFVVGSGFFGLTIAERVATQ
MSMEG_6404|M.smegmatis_MC2_155      ------------MTSISHPVAPSQSTGNFDLFVVGSGFFGLTIAERAATQ
TH_2083|M.thermoresistible__bu      ------------------------MTERVDLIVVGSGFFGLTIAERVATQ
Mflv_1159|M.gilvum_PYR-GCK          MSQSRPARLGQRGSGGRGRIPLLPMNSGFDLFVVGSGFFGLTIAERAATQ
Mvan_5650|M.vanbaalenii_PYR-1       -MISPDPRAAAR-----------PQADGFDLFVVGSGFFGLTIAERAATQ
MAB_0170|M.abscessus_ATCC_1997      --MTADEPLARRADS--------GENQQFDLIVVGSGFFGLTIAERAATQ
                                                                .**:**************.***

Rv3809c|M.tuberculosis_H37Rv        LDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVR
Mb3839c|M.bovis_AF2122/97           LDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNKRVWDYVR
MAV_0208|M.avium_104                LGKRVLVVERRPHIGGNAYSEPEPHTGIEVHKYGAHLFHTSNKRVWDYVR
MMAR_5373|M.marinum_M               LGKRVLVVERRPHIGGNAYSEPEPQTGIEVHKYGAHLFHTSNKKVWDYVG
MUL_4993|M.ulcerans_Agy99           LGKRVLVVERRPHIGGNAYSEPEPQTGIEVHKYGAHLFHTSNKKVWDYVG
MLBr_00092|M.leprae_Br4923          LGKRVLIVEKRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSSKRVWDYVR
MSMEG_6404|M.smegmatis_MC2_155      LGKRVLVIERRPHIGGNAYSEPEPETGIEVHKYGAHLFHTSNKRVWDYVR
TH_2083|M.thermoresistible__bu      LGKRVLVVERRGHIGGNAYSEPEPETGIEVHKYGAHLFHTSNKRVWDYVR
Mflv_1159|M.gilvum_PYR-GCK          LNKRVLVIERRPHIGGNAYSEAEPQTGIEVHKYGAHLFHTSNQRVWDYVR
Mvan_5650|M.vanbaalenii_PYR-1       LGKRVLVVERRPHLGGNAYSEAEPQTGIEVHKYGAHLFHTSNQRVWDYVR
MAB_0170|M.abscessus_ATCC_1997      LDKRVLVVERRHHIGGNAYSEPEPQTGIEVHKYGAHLFHTSNKRVWDYVR
                                    *.****::*:* *:*******.**.****************.::***** 

Rv3809c|M.tuberculosis_H37Rv        QFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQ
Mb3839c|M.bovis_AF2122/97           QFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPEQARQLIAEQ
MAV_0208|M.avium_104                QFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFSPEEARKLIAEQ
MMAR_5373|M.marinum_M               QFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFSPAEARQLIAEQ
MUL_4993|M.ulcerans_Agy99           QFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFSPAEARQLIAEQ
MLBr_00092|M.leprae_Br4923          QFTEFTDYRHRVFAVHNGQVYQFPMGLGLVSQFFGRYFTPDEARQLIAEQ
MSMEG_6404|M.smegmatis_MC2_155      QFTDFTGYQHRVFAMHNGQAYQFPMGLGLVSQFFGRYFSPDEARALIAEQ
TH_2083|M.thermoresistible__bu      QFTDFTNYQHRVFALHNGQAYPLPMGLGLVSQFFGRYFTPDEARKLIAEQ
Mflv_1159|M.gilvum_PYR-GCK          QFTEFTGYQHRVFALHAGQAYQFPMGLGLVSQFFGRYFTPDEARALIREQ
Mvan_5650|M.vanbaalenii_PYR-1       QFTEFTGYQHRVFALHNGQAYQFPMGLGLVSQFFGRYYTPDEARALIAEQ
MAB_0170|M.abscessus_ATCC_1997      QFTEFTGYQHRVFAMHQGQSYQFPLGLGLVSQFFGRYFTPDEARALIAEQ
                                    ***:**.*:*****:* ** * :*:**********:*::* :** ** **

Rv3809c|M.tuberculosis_H37Rv        AAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANIT
Mb3839c|M.bovis_AF2122/97           AAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANIT
MAV_0208|M.avium_104                AAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPASNIT
MMAR_5373|M.marinum_M               AAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKQLPAANIT
MUL_4993|M.ulcerans_Agy99           AAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKQLPAAHIT
MLBr_00092|M.leprae_Br4923          ASEIDTADAKTLEEKAISLIGRPLYEAFVKGYTAKQWQTDPAELPAAVIS
MSMEG_6404|M.smegmatis_MC2_155      ASEIDTKDAKNFEEKAISLVGRPLYEAFIKHYTAKQWQTDPKDLPASNIT
TH_2083|M.thermoresistible__bu      ASEIDTAEAKNLEEKAISLIGRPLYEAFIKNYTAKQWQTDPKELPASNIT
Mflv_1159|M.gilvum_PYR-GCK          AAEISTADAQNLEEKAISLIGRPLYEAFVKHYTAKQWQTDPKTLPASNIT
Mvan_5650|M.vanbaalenii_PYR-1       AAEIDTADAQNLEEKAISLIGRPLYEAFVKHYTAKQWQTDPRQLPASNIT
MAB_0170|M.abscessus_ATCC_1997      AAEITTADAANLEEKAISLIGRPLYEAFVKHYTAKQWQTDPVDLPAAVIN
                                    *:** * :* .:*******:********:* **********  ***: *.

Rv3809c|M.tuberculosis_H37Rv        RLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVR
Mb3839c|M.bovis_AF2122/97           RLPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVR
MAV_0208|M.avium_104                RLPVRYTFDNRYFSDTYEGLPVDGYTAWLQNMAAHENIEVRLNTDWFDVR
MMAR_5373|M.marinum_M               RLPVRYTFDNRYFSDTYEGLPVDGYTAWLQNMAADDRIEVRLDTDWFDVR
MUL_4993|M.ulcerans_Agy99           RLPVRYTFDNRYFSDTYEGLPVDGYTAWLQNMAADDRIEVRLDTDWFDVR
MLBr_00092|M.leprae_Br4923          RLPVRYTFDNRYFSDIYEGLPVDGYTAWCTKMADDDRIEVRFGTDWFDVA
MSMEG_6404|M.smegmatis_MC2_155      RLPVRYTFDNRYFNDTYEGLPVEGYTKWLENMAADERIEVRLDTDWFDVR
TH_2083|M.thermoresistible__bu      RLPVRYTFDNRYFNDTYEGLPVHGYTAWLENMAADERIEVRLNTDWFEVR
Mflv_1159|M.gilvum_PYR-GCK          RLPVRYTFDNRYFNDTYEGLPVDGYTAWLQNMAADDRIEVRLDTDWFDVR
Mvan_5650|M.vanbaalenii_PYR-1       RLPVRYTFDNRYFNDTYEGLPVDGYTAWLEKMAADDRIEVRLNTDWFDVR
MAB_0170|M.abscessus_ATCC_1997      RLPVRYTFDNRYFNDTYEGLPVDGYTAWLQNMAADDRIEVRLDTDWFQVR
                                    *************.* *****..*** *  :** ...****:.****:* 

Rv3809c|M.tuberculosis_H37Rv        GQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTA
Mb3839c|M.bovis_AF2122/97           GQLRPGSPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTA
MAV_0208|M.avium_104                DGLRAGSPEAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTP
MMAR_5373|M.marinum_M               DELRAANPGAPVVYTGPLDRYFDYAEGRLGWRTLDFDVEVLPIGDFQGTS
MUL_4993|M.ulcerans_Agy99           DELRAANPEAPVVYTGPLDRYFDYAEGRLGWRTLDFDVEVLPIGDFQGTS
MLBr_00092|M.leprae_Br4923          DQLRADSLGAPVVYTGPLDRYFDYAAGRLGWRTLDFEVEVLPIGDFQGTP
MSMEG_6404|M.smegmatis_MC2_155      DDLRAANPDAPVVYTGPLDRYFDYAEGRLGWRTLDFELEVLETGDFQGTP
TH_2083|M.thermoresistible__bu      DELRAANPDAPVVYTGPLDRYFDYAEGRLGWRTLDFELEVLDTGDFQGTS
Mflv_1159|M.gilvum_PYR-GCK          DQLRAENPDAPVIYTGPLDRYFDYAEGRLGWRTLDFELEVLQTGDFQGTP
Mvan_5650|M.vanbaalenii_PYR-1       DQLRAENPDAPVVYTGPLDRYFDYAEGRLGWRTLDFELEVLQTGDFQGTP
MAB_0170|M.abscessus_ATCC_1997      ADLRAANPAAPVVYTGPLDRYFDYAEGRLGWRTLDFEVEVLDTGDFQGTP
                                      **. .  ***:************ **********::***  ******.

Rv3809c|M.tuberculosis_H37Rv        VMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYP
Mb3839c|M.bovis_AF2122/97           VMNYNDLDVPYTRIHEFRHFHPERDYPTDKTVIMREYSRFAEDDDEPYYP
MAV_0208|M.avium_104                VMNYNDLDVPYTRIHEFRHFHTERDYPTDKTVIMREYSRFAEDDDEPYYP
MMAR_5373|M.marinum_M               VMNYNDLDVPYTRIHEFRHFHPEREYPSDQTVIMREYSRFAEDEDEPYYP
MUL_4993|M.ulcerans_Agy99           VMNYNDLDVPYTRIHEFRHFHPEREYPSDQTVIMREYSRFAEDEDEPYYP
MLBr_00092|M.leprae_Br4923          VMNYSDLDVPFTRIHEFRHFHRERHYPIDKTVIMREYSRFAGYDDEPYYP
MSMEG_6404|M.smegmatis_MC2_155      VMNYNDLDVPYTRIHEFRHFHPERTYPTDKTVIMREYSRFADNDDEPYYP
TH_2083|M.thermoresistible__bu      VMNYSDLDVPYTRIHEFRHFHPERSYPTDRTVIMREYSRFAGDDDEPYYP
Mflv_1159|M.gilvum_PYR-GCK          VMNYNDADVPYTRIHEFRHFHPERDYPDDKTVIMREYSRFAENDDEPYYP
Mvan_5650|M.vanbaalenii_PYR-1       VMNYNDADVPYTRIHEFRHFHPERAYPTDKTVIMREYSRFAEHDDEPYYP
MAB_0170|M.abscessus_ATCC_1997      VMNYNDADVPYTRIHEFRHFHPERAYPTDKTVIMREFSRFAEGTDEPYYP
                                    ****.* ***:********** ** ** *:******:****   ******

Rv3809c|M.tuberculosis_H37Rv        INTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNM
Mb3839c|M.bovis_AF2122/97           INTEADRALLATYRARAKSETASSKVLFGGRLGTYQYLDMHMAIASALNM
MAV_0208|M.avium_104                INTEADRALLAAYRARAKAETASAKVLFGGRLGTYQYLDMHMAIASALNM
MMAR_5373|M.marinum_M               INTEADRALLAAYRTRAKSETASSKVLFGGRLGTYQYLDMHMAIASALSM
MUL_4993|M.ulcerans_Agy99           INTEADRALLAAYRTRAKSETASSKVLFGGRLGTYQYLDMHMAIASALSM
MLBr_00092|M.leprae_Br4923          INTEADRAMLAAYRAKAKSETASSKVLFGGRLGTYQYLDMHMAIAAALNM
MSMEG_6404|M.smegmatis_MC2_155      INTEADRAVLAAYRARAKAETASAKVLFGGRLGTYQYLDMHMAIASALSM
TH_2083|M.thermoresistible__bu      INTETDRAVLAAYRARAKEETATAKVLFGGRLGTYQYLDMHMAIASALNM
Mflv_1159|M.gilvum_PYR-GCK          INTDADRAVLAAYRARAKAETASTKVLFGGRLGTYQYLDMHMAIASALNM
Mvan_5650|M.vanbaalenii_PYR-1       INTDADRAVLAAYRARAKAETASSKVLFGGRLGTYQYLDMHMAIASALNM
MAB_0170|M.abscessus_ATCC_1997      INTESDRAILAAYRTRAKQETASAKVLFGGRLGTYQYLDMHMAIASALSM
                                    ***::***:**:**::** ***::*********************:**.*

Rv3809c|M.tuberculosis_H37Rv        YDNVLAPHLRDGVPLLQDGA-----------------
Mb3839c|M.bovis_AF2122/97           YDNVLAPHLRDGVPLLQDGA-----------------
MAV_0208|M.avium_104                YDNVLAPHLRDGASLTEAQSKQESGA-----------
MMAR_5373|M.marinum_M               YDNVLAPHLRDGRPLAEPPAEESARG-----------
MUL_4993|M.ulcerans_Agy99           YDNVLAPHLRDGRPLAEPPAEESARG-----------
MLBr_00092|M.leprae_Br4923          YDNILAPHLRDGSPLMEEPAVAAAQHAAPAIGREGGA
MSMEG_6404|M.smegmatis_MC2_155      FDNVLAPHLSEGASLVT-----EDESSKA--------
TH_2083|M.thermoresistible__bu      YDNVLAPHLRDGVPLTSTGAAGEPESSR---------
Mflv_1159|M.gilvum_PYR-GCK          YDNVLQPHLRDGTPLAEPDTESRQA------------
Mvan_5650|M.vanbaalenii_PYR-1       YDNTLAPHLRDGAPLADPETESSGS------------
MAB_0170|M.abscessus_ATCC_1997      YDNVLAPHLADGAPLSGGDDNE---------------
                                    :** * *** :* .*