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SHTWGRPASHQDRGWAVIDVETSGFRPGQARIISLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTA AMLDGQPQFADIAGEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRLQLGVDNL RLETLAAHWGVPQQRPHDAFDDVRVLTGILAAALESARELDVWLPVHPVTRRRWPNGRVTHDELRPLKAV AARMACPYLNPGRYVQGRPLVQGMRVGLAAEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEH GKGYHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVAPVEKQLALF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3711c | dnaQ | - | 100% (329) | DNA polymerase III subunit epsilon |
| M. tuberculosis H37Rv | Rv2191 | - | 5e-14 | 26.73% (303) | hypothetical protein Rv2191 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3738c | dnaQ | 0.0 | 99.09% (329) | DNA polymerase III subunit epsilon |
| M. gilvum PYR-GCK | Mflv_1292 | - | 1e-130 | 67.69% (325) | DNA polymerase III subunit epsilon |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0329 | - | 1e-119 | 62.15% (325) | DNA polymerase III subunit epsilon |
| M. marinum M | MMAR_5228 | dnaQ | 1e-153 | 78.72% (329) | DNA polymerase III (epsilon subunit) DnaQ |
| M. avium 104 | MAV_0391 | - | 1e-155 | 81.54% (325) | DNA polymerase III subunit epsilon |
| M. smegmatis MC2 155 | MSMEG_6275 | - | 1e-125 | 66.15% (325) | DNA polymerase III subunit epsilon |
| M. thermoresistible (build 8) | TH_2284 | dnaQ | 1e-122 | 66.34% (309) | PROBABLE DNA POLYMERASE III (EPSILON SUBUNIT) DNAQ |
| M. ulcerans Agy99 | MUL_4303 | dnaQ | 1e-152 | 78.12% (329) | DNA polymerase III subunit epsilon |
| M. vanbaalenii PYR-1 | Mvan_5519 | - | 1e-126 | 66.77% (325) | DNA polymerase III subunit epsilon |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3711c|M.tuberculosis_H37Rv ------------MSHT----WGRPASHQDRGWAVIDVETSGFRPGQARII
Mb3738c|M.bovis_AF2122/97 ------------MSHT----WGRPASHQDRGWAVIDVETSGFRPGQARII
MAV_0391|M.avium_104 ------------MSAVC---WGRPASEPDAGWAVIDVETSGFRPGQARII
MMAR_5228|M.marinum_M ------------MSQN----WGRPASHPGEGWAVVDVETSGFRPGHARVI
MUL_4303|M.ulcerans_Agy99 ------------MSQN----WGRPASHPGEGWAVVDVETSGFRPGHARVI
Mflv_1292|M.gilvum_PYR-GCK MRHVRAPCHPRIMSSTAGRRWGRPAHEDGAGWAVVDVETSGFRPGQARIV
Mvan_5519|M.vanbaalenii_PYR-1 ------------MSSTAGSRWGRPADQPGAGWAVVDVETSGFRPGQARIV
MSMEG_6275|M.smegmatis_MC2_155 --MSRAP-----LSSTP-QLWGRPADEPGSGWAVVDVETTGFRPGQARIV
TH_2284|M.thermoresistible__bu ------------------------------------VETTGFRPGQARIV
MAB_0329|M.abscessus_ATCC_1997 -----------------MPIWGQTPDHS-PKWVVVDLETSGFQPGRARVI
:**:**:**:**::
Rv3711c|M.tuberculosis_H37Rv SLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTAAMLDGQPQFADIA
Mb3738c|M.bovis_AF2122/97 SLAVLGLDAAGRLEQSVVSLLNPKVDPGPTHVHGLTAAMLDDQPQFADIA
MAV_0391|M.avium_104 SLAVLGLDAGGKVEQSVVSLLNPGVDPGPTHVHGLTAAMLEDQPQFADIA
MMAR_5228|M.marinum_M SVAALGLDAAGNVEHSVVSLLNPGVDPGPTHVHGLTAAMLEDQPQFADIV
MUL_4303|M.ulcerans_Agy99 SVAALGLDAAGNVEHSVVSLLNPGGDPGPTHVHGLTAAMLEDQPQFADIV
Mflv_1292|M.gilvum_PYR-GCK SVAALALSDDGNVEKSLYSLLDPGVDPGPTHVHGLTAEMLEGQPTFGDVV
Mvan_5519|M.vanbaalenii_PYR-1 SVAALALSDDGNVEKSLYSLLDPGVDPGPTHVHGLTAEMLAGQPAFGDVV
MSMEG_6275|M.smegmatis_MC2_155 SVAALAVGDDGSVEHSMSSLLNPGVDPGPTHVHGLTAEMLEGQPCFADVV
TH_2284|M.thermoresistible__bu SIAALAVGDDGNVERSVATLLNPGVDPGPTHIHGLTADMLAGQPQFADIV
MAB_0329|M.abscessus_ATCC_1997 SVAALAMDADGTITDSVVSLLNPGVDPGPTHVHGLTPEMLEGQPEFSDIA
*:*.*.:. * : *: :**:* ******:****. ** .** *.*:.
Rv3711c|M.tuberculosis_H37Rv GEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRL
Mb3738c|M.bovis_AF2122/97 GEVVDVLRGRTLVAHNVAFDYAFLAAEAEIAEAELPVDFVMCTVELARRL
MAV_0391|M.avium_104 GDVVEVLRGRTLVAHNVAFDYAFLAAEAELAGIELPVDTVMCTVELARRL
MMAR_5228|M.marinum_M GDLTELLRGRTLVAHNVAFDYSFLAAEAELADAELPVDSVMCTVELARRL
MUL_4303|M.ulcerans_Agy99 GDLTELLRGRTLVAHNVAFDYSFLAAEAELTDAELPVDSVMCTVELARRL
Mflv_1292|M.gilvum_PYR-GCK GDLCEVLRGRTLVAHNVGFDYSFLSAEAELVGAELPIDTVMCTVELARRL
Mvan_5519|M.vanbaalenii_PYR-1 GDLIEVLRGRTLVAHNVGFDYSFLTAEAEMVHAELPVDTVMCTVELARRL
MSMEG_6275|M.smegmatis_MC2_155 DELIEVLRGRTLVAHNAGFDYSFLAAEAELVGAELPIDTAMCTVELARRL
TH_2284|M.thermoresistible__bu DDLIDILRGRTLVAHNVAFDYAFLVAEAELIDAELPIDSVMCTIELARRM
MAB_0329|M.abscessus_ATCC_1997 PDLIALLRGRTLVAHNVGFDYSFLAAEAELVGAELPTEAVMCTVELTRRL
:: :**********..***:** ****: *** : .***:**:**:
Rv3711c|M.tuberculosis_H37Rv QLGVDNLRLETLAAHWGVPQQRPHDAFDDVRVLTGILAAALESARELDVW
Mb3738c|M.bovis_AF2122/97 QLGVDNLRLETLAAHWGVPQQRPHDAFDDARVLTGILAAALESARELDVW
MAV_0391|M.avium_104 DLGIDNLRLETLAAYWGVTQQRPHDAFDDAMVLTGVLASALQRARERDIW
MMAR_5228|M.marinum_M ELGIDNLRLETLAAHWGVTQERPHDAFDDALVLSGILAPALQRARERDVW
MUL_4303|M.ulcerans_Agy99 ELGIDNLRLETLAAHWGVTQERPHDAFDDALVLSGILAPALQRARERDVW
Mflv_1292|M.gilvum_PYR-GCK DLGLENLRLETLAAHWGVTQMRPHDALDDAMVLAQILKPVLVRAQERRKW
Mvan_5519|M.vanbaalenii_PYR-1 DLGLDNLRLETLAAHWGVTQMKPHDALDDAMVLAQILKPVLVRAQERRKW
MSMEG_6275|M.smegmatis_MC2_155 ELGTENLRLETLAAHWGVTQMKPHDALDDALVLAQILKPTLARARDRKVW
TH_2284|M.thermoresistible__bu QLGTENLRLETLAAHWGVTQLRAHDALDDALVLTQILKPTLALARERRTW
MAB_0329|M.abscessus_ATCC_1997 ELDTPNLRLETLAAHWGVEQLKAHDAYDDARVLAEVLPKVLERARERGTW
:*. *********:*** * :.*** **. **: :* .* *:: *
Rv3711c|M.tuberculosis_H37Rv LPVHPVTRRRWPNGRVTHDELRPLKAVAARMACPYLNPGRYVQGRPLVQG
Mb3738c|M.bovis_AF2122/97 LPVHPVTRRRWPNGRVTHDELRPLKALAARMACPYLNPGRYVQGRPLVQG
MAV_0391|M.avium_104 LPVHPVTRRRWPNGRVTHDELRPLKVLASRMPCPYLNPGPYVGGRPLVQG
MMAR_5228|M.marinum_M LPIHPVTRRRWPNGRVTHDELRPLKALASRMPCPYLNPGRYVCDRPLVQG
MUL_4303|M.ulcerans_Agy99 LPIHPVTRRRWPNGRVTHDELRPLKALASRMPCPYLNPGRYVCDRPLVQG
Mflv_1292|M.gilvum_PYR-GCK LPVHPVGRRTWPNGRVTHDEFRPLKALAARMACPYANPGRFVSGRPLVQG
Mvan_5519|M.vanbaalenii_PYR-1 LPVHPVSRRTWPNGRITHDEFRPLKALAARMPCAYANPGVFVAGRPLVQG
MSMEG_6275|M.smegmatis_MC2_155 LPLRQLTRKRWPNGHVTHDELRPLKVEASRLPCRYANPGPFVAGRPLVQG
TH_2284|M.thermoresistible__bu LPLRPVTRRHWPNGRTTHEQLRPLKALASRIPCRYTNPGRYIAGRPLVQG
MAB_0329|M.abscessus_ATCC_1997 LPIRETTRKRWPNGRVTHDELRPLKTLASRQPCHWLNPGPYTAGQPLVQG
**:: *: ****: **:::****. *:* .* : *** : .:*****
Rv3711c|M.tuberculosis_H37Rv MRVGLAAEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKG
Mb3738c|M.bovis_AF2122/97 MRVGLAAEVKRTHEELVERILHAGLAYSDVVDRDTSLVVCNATAPEHGKG
MAV_0391|M.avium_104 MRVALAAEVERTHEELVERILHAGLAYSDTVDRETSLVVCNDPAAEHGKG
MMAR_5228|M.marinum_M MRVALAAEVGRTHEELVERILHAGLAYSDGVDRETSLVVCNEDAPDQGKG
MUL_4303|M.ulcerans_Agy99 MRVALAAEVGRTHEELVERILHAGLAYSDGVDRETSLVVCNEDAPDQGKG
Mflv_1292|M.gilvum_PYR-GCK MRVALAAEVGHTYDELIERIVHAGLAYTESVDAFTSLVVCDAAAPEQGKG
Mvan_5519|M.vanbaalenii_PYR-1 MRVALSAEVGHTHEELVERILHAGLAFTEVVDGHTSLVVCDDPAPEQGKG
MSMEG_6275|M.smegmatis_MC2_155 MRVALSAEVVRTHEELLERVLHAGLAYSDMVDLQTSLVICNDPAPEQGKG
TH_2284|M.thermoresistible__bu MQVALSAEVTHTHEELIERILHAGLAYTDDITGQTSLVVCNEPNPEHGKG
MAB_0329|M.abscessus_ATCC_1997 MRVALSSEVSRTHEELIEQIMQAGLAYADAVDEDTSLVICNQENPEQGKG
*:*.*::** :*::**:*::::****::: : ****:*: .::***
Rv3711c|M.tuberculosis_H37Rv YHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVAPVEKQLALF
Mb3738c|M.bovis_AF2122/97 YHALQLGVPVMPEARFMECIGAVVGGASVEDFTDVAPVEKQLALF
MAV_0391|M.avium_104 YLARQLGVPVISDAQFLDCVRAVIGGTSMDEFTDATP-DPQLALF
MMAR_5228|M.marinum_M YHARQLGVPVLTDTQFMDRVGCVLGGTSAEKFTDHTLVEEQFALF
MUL_4303|M.ulcerans_Agy99 YHARQLGVPVLTDTQFMDRVGCVLGGTSAEKFTDHTLVEEQFALF
Mflv_1292|M.gilvum_PYR-GCK YQAGEFGVPMLPSDEFLQRLDAVIGGSAVEEFAEPSPAGDQFALF
Mvan_5519|M.vanbaalenii_PYR-1 YQAGGFGVPTLGSAEFLRHLDTVIGGSAIEEFADQASAGDQFTLF
MSMEG_6275|M.smegmatis_MC2_155 YQAKELGVPLVRDDEFMRLLDHVVGGADVETFVDTTADGDQYALF
TH_2284|M.thermoresistible__bu FHAADLGVPLMSDTEFMAALDRVVGGVEIDEFVDTTKAGEQYALF
MAB_0329|M.abscessus_ATCC_1997 FHARSLGVPLLDDRTFMTEVRRVVGGTDIEQFTVPSRAGAQYSLF
: * :*** : . *: : *:** : *. : * :**