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M. tuberculosis H37Rv Rv3629c (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 4067957 - 4069054
length: 365

STFRIFGFSLLMTVVALVTGYLHGGPTALFLLAVLALLEVSLSFDNAIINAAILQRMSPFWQRMFLTIGI
LIAVFGMRLVFPLAIIWTTAGLDPVRAMELALRPPAHGALEFADGSPSYEKLITAAHPQIAAFGGMFLLM
LFLDFVVHDRDIKWLKWIEVPFARIGRLGQVPVIVASVGLVLAGALLTHSSDQRGTVLIAGLLGMVTYLV
VNGISRAFRPAGLGEATPGVQARQAAGKAGCALFLYLEVLDAAFSFDGVTGAFAITTDPIIIALGLGVVG
AMFVRSITIYLVRQDTLDRYVYLEHGAHWAIGALAIILLLSIDHRFAVPEWVTASVGVVFIGAAFTESVR
RNRLTVRSPTKFGS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3629c--100% (365)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3653c-0.0100.00% (365) hypothetical protein Mb3653c
M. gilvum PYR-GCK-----
M. leprae Br4923MLBr_00205-1e-13366.20% (361) hypothetical protein MLBr_00205
M. abscessus ATCC 19977MAB_1276c-2e-0526.11% (157) hypothetical protein MAB_1276c
M. marinum MMMAR_5129-1e-15576.55% (354) hypothetical protein MMAR_5129
M. avium 104MAV_0528-1e-14976.00% (350) integral membrane protein
M. smegmatis MC2 155-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4205-1e-15475.99% (354) hypothetical protein MUL_4205
M. vanbaalenii PYR-1Mvan_0331-2e-0525.20% (123) integral membrane protein TerC

CLUSTAL 2.0.9 multiple sequence alignment


Rv3629c|M.tuberculosis_H37Rv        -MSTFRIFGFSLLMTVVALVTGYLHGGPTALFLLAVLALLEVSLSFDNAI
Mb3653c|M.bovis_AF2122/97           -MSTFRIFGFSLLMTVVALVTGYLHGGPTALFLLAVLALLEVSLSFDNAI
MMAR_5129|M.marinum_M               -MTTIRVFGLSLLVTAAALVAGYWHGGVTALFLLVVLAILEISLSFDNAI
MUL_4205|M.ulcerans_Agy99           -MTTIRVFGLSLLVTAAALIAGYWHGGVTALFLLVVLAILEISLSFDNAI
MAV_0528|M.avium_104                -MPALRTFGVSLLVTAAALVLGYAYGGPKSLYLLLVLAALEVSLSFDNAV
MLBr_00205|M.leprae_Br4923          -MAAFRGFGISLLTTAIALLVAYIYGGLASLLPLIVLAIFEVSLSFDNAI
MAB_1276c|M.abscessus_ATCC_199      -MPSAKQYSDPLTRNDIGLLV-----------------------------
Mvan_0331|M.vanbaalenii_PYR-1       MVVPLWAWAAVLGVILAMLAIDLFAHRDAHVVTVREAAAWSAVWVTLGLA
                                     : .   :.  *      *                               

Rv3629c|M.tuberculosis_H37Rv        INAAILQRMSPFWQRMFLTIGILIAVFGMRLVFPLAIIWTTAGLDPVRAM
Mb3653c|M.bovis_AF2122/97           INAAILQRMSPFWQRMFLTIGILIAVFGMRLVFPLAIIWTTAGLDPVRAM
MMAR_5129|M.marinum_M               INATILKQMSQFWQQMFLTIGIVIAVFGMRLVFPLTIVWVTAGLDPVRAM
MUL_4205|M.ulcerans_Agy99           INATILKQMSQFWQQMFLTIGIVIAVFGMRLVFPLTIVWVTAGLDPVRAM
MAV_0528|M.avium_104                INAAVLKQMSRFWQRMFLTIGILVAVFGMRLLFPLLIVWATAGLDPVRAL
MLBr_00205|M.leprae_Br4923          INAAILKQMSRFWRKMFLTIGILIAAFGMRLIFPAVIVWATAKLDPVRTM
MAB_1276c|M.abscessus_ATCC_199      ---------------LRVAVGLTLCWDGLNVVF-----------------
Mvan_0331|M.vanbaalenii_PYR-1       FGAIVWWMWGAEFAAQYYAGYVIEKSLAVDNVFVFAIIFSYFAVPREYQH
                                                      :  :     .:  :*                 

Rv3629c|M.tuberculosis_H37Rv        ELALRPPAHGALEFADGSPSYEKLITAAHPQIAAFGGMFLLMLFLDFVVH
Mb3653c|M.bovis_AF2122/97           ELALRPPAHGALEFADGSPSYEKLITAAHPQIAAFGGMFLLMLFLDFVVH
MMAR_5129|M.marinum_M               RLALNPPPGGALDFPDGSPSYEKLISAAHPQIAAFGGMFLLTLFLDFVFN
MUL_4205|M.ulcerans_Agy99           RLALNPPPGGALDFPDGSPSYEKLISAAHPQIAAFGGMFLLTLFLDFVFN
MAV_0528|M.avium_104                ELALRPPPHGALEFPDGSPSYQKLLTAAHPQIAAFGGIFLLMLFLDFLLI
MLBr_00205|M.leprae_Br4923          DLALHPPPNHALEFPDGSPSYQKLIMSAHPQIAAFGGTFLLMLFLDFVFQ
MAB_1276c|M.abscessus_ATCC_199      ----------------ASEQFKQLGSTAG---------------------
Mvan_0331|M.vanbaalenii_PYR-1       RVLFYG--------VLGALVFRAVFIAAG---------------------
                                                    .:  :. :  :*                      

Rv3629c|M.tuberculosis_H37Rv        DRDIKWLKWIEVPFARIGRLGQVPVIVASVGLVLAGALLTHSSDQRGTVL
Mb3653c|M.bovis_AF2122/97           DRDIKWLKWIEVPFARIGRLGQVPVIVASVGLVLAGALLTHSSDQRGTVL
MMAR_5129|M.marinum_M               DREIKWLKWIEAPFARIGRLGQVHVMVACVTLIFAGPGLTDSSDDLGTVM
MUL_4205|M.ulcerans_Agy99           DREIKWLKWIEAPFARIGRLGQVHVMVACVTLIFAGPGLTDSSDDLGIVM
MAV_0528|M.avium_104                DRDIKWLKWIEVPFARIGRLGQVSVVLSGLTLVLVGTGLTHSSQEAVTVL
MLBr_00205|M.leprae_Br4923          DRDIKWLKWIEAPFTRIGRLGPLSVVAIFV-LVLIATALTHSGDERAKVL
MAB_1276c|M.abscessus_ATCC_199      -----------------------------------------ASADLAARV
Mvan_0331|M.vanbaalenii_PYR-1       -------SVLIASFAWILYIFGAFLVATGIQMALHRNETINPERSMVLRL
                                                                             .  .    :

Rv3629c|M.tuberculosis_H37Rv        IAGLLGMVTYLVVNGISRAFRPAGLGEATPGVQARQAAGKAGCALFLYLE
Mb3653c|M.bovis_AF2122/97           IAGLLGMVTYLVVNGISRAFRPAGLGEATPGVQARQAAGKAGCALFLYLE
MMAR_5129|M.marinum_M               VAGLLGLVTYLVVNGLSRALQPPRVGAGPGELAAQGAVGKAGFMLFMYLE
MUL_4205|M.ulcerans_Agy99           VAGLLGLVTYLVVNGLSRALQPPRVGAGPGELAAQGAVGKAGFMLFMYLE
MAV_0528|M.avium_104                TAGLLGMVAYLVVNGLSRAFRPSGVGQPQP---AGPATGWAGLSLFLYLE
MLBr_00205|M.leprae_Br4923          IAGLLSLVTYLLVSVLNRAFRPPDIDTASG----RRMAGRAGLVRFLYLE
MAB_1276c|M.abscessus_ATCC_199      LAGTYSIGGALLVAGLLTPLG-----------------------------
Mvan_0331|M.vanbaalenii_PYR-1       FRRLISVTDTYHGQKFLIRQAG-------------RWVATPLLAVLVLVE
                                         .:        :                                  

Rv3629c|M.tuberculosis_H37Rv        VLDAAFSFDGVTGAFAITTDPIIIALGLGVVGAMFVRSITIYLVRQDTLD
Mb3653c|M.bovis_AF2122/97           VLDAAFSFDGVTGAFAITTDPIIIALGLGVVGAMFVRSITIYLVRQDTLD
MMAR_5129|M.marinum_M               VLDASFSFDGVTGAFAITSDPIVIALGLGLVGAMFVRSITIYLVRQDALD
MUL_4205|M.ulcerans_Agy99           VLDASFSFDGVTGAFAITSDPIVIALGLGLVGAMFVRSITIYLVRQDALD
MAV_0528|M.avium_104                VLDAAFSFDGVTGAFAITSDPVVIVLGLGVVGAMFVRSITIYLVHQETLD
MLBr_00205|M.leprae_Br4923          ILDATFSFDGVTGAFAITSDPVIIALGLGLISSVFIRSITIYLVHQDALD
MAB_1276c|M.abscessus_ATCC_199      --------------------------GCAVLGSMLYAATLSYSVRHDLLQ
Mvan_0331|M.vanbaalenii_PYR-1       VTDIVFAVDSIPAIFAVTQQPFLVFTSNAFA---ILGLRAMYFLLADLMH
                                                              . ..    :      * :  : :.

Rv3629c|M.tuberculosis_H37Rv        RYVYLEHGAHWAIGALAIILL----LSIDHRFAVPEWVTASVGVVFIG--
Mb3653c|M.bovis_AF2122/97           RYVYLEHGAHWAIGALAIILL----LSIDHRFAVPEWVTASVGVVFIG--
MMAR_5129|M.marinum_M               RYVYLEHGAHWAIGALAVIML----MSIDHHLQIPEWITASIGVVFIG--
MUL_4205|M.ulcerans_Agy99           RYVYLEHGAHWAIGALAVIML----MSIDHHLQIPEWITASIGVVFIG--
MAV_0528|M.avium_104                RYVYLEHGAHWAIGALAVIML----ASIEPRLTVPEPVTASVGVFFIG--
MLBr_00205|M.leprae_Br4923          RYVYLEYGAHWAIGALSVMML----LSVEPRFEILEAVTALVGVLFIG--
MAB_1276c|M.abscessus_ATCC_199      SGTAVQFPLLLAAAAMAVILMGPGRISVDGRFGREEWPNAVTSVLVVAGF
Mvan_0331|M.vanbaalenii_PYR-1       RFIYLKLGLALVLVWVGVKMLLLEIYKIPTGISLAVVVALLAIAITASWI
                                        ::     .   :.: ::     .:   :           ..  .  

Rv3629c|M.tuberculosis_H37Rv        -AAFTESVRRNRLTVRSPTKFGS----
Mb3653c|M.bovis_AF2122/97           -AAFTESVRRNRLTVRSPTKFGS----
MMAR_5129|M.marinum_M               -AAFTNSVVRNRRAGG-----------
MUL_4205|M.ulcerans_Agy99           -AAFTNSVVRNRRAGG-----------
MAV_0528|M.avium_104                -TAVGFSVLRRRRESGRASAPGP----
MLBr_00205|M.leprae_Br4923          -AALTWSVFRNHREVKACT--------
MAB_1276c|M.abscessus_ATCC_199      GAAIAAWVLVKGTNPLS----------
Mvan_0331|M.vanbaalenii_PYR-1       RTRNGATPPTETTLVDAPKIDTFHPNR
                                     :        .