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M. tuberculosis H37Rv Rv3607c (folB)

annotation: PROBABLE DIHYDRONEOPTERIN ALDOLASE FOLB (DHNA)
coordinates: 4048744 - 4049145
length: 133

ADRIELRGLTVHGRHGVYDHERVAGQRFVIDVTVWIDLAEAANSDDLADTYDYVRLASRAAEIVAGPPRK
LIETVGAEIADHVMDDQRVHAVEVAVHKPQAPIPQTFDDVAVVIRRSRRGGRGWVVPAGGAV*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3607cfolB-100% (133)PROBABLE DIHYDRONEOPTERIN ALDOLASE FOLB (DHNA)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3637cfolB9e-74100.00% (133) dihydroneopterin aldolase FolB
M. gilvum PYR-GCKMflv_1419-3e-4672.36% (123) dihydroneopterin aldolase
M. leprae Br4923MLBr_00225folB3e-5474.81% (131) putative dihydroneopterin aldolase
M. abscessus ATCC 19977MAB_0536-2e-4166.13% (124) dihydroneopterin aldolase (FolB)
M. marinum MMMAR_5110folB6e-5880.45% (133) dihydroneopterin aldolase FolB
M. avium 104MAV_0545folB1e-5679.70% (133) dihydroneopterin aldolase
M. smegmatis MC2 155MSMEG_6102folB2e-4874.80% (123) dihydroneopterin aldolase
M. thermoresistible (build 8)TH_0988folX2e-4570.73% (123) PROBABLE DIHYDRONEOPTERIN ALDOLASE FOLB (DHNA)
M. ulcerans Agy99MUL_4189folB8e-5778.95% (133) dihydroneopterin aldolase FolB
M. vanbaalenii PYR-1Mvan_5369-4e-4471.90% (121) dihydroneopterin aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1419|M.gilvum_PYR-GCK          MTDRIELRGLTVRGNHGVFDHERRDGQDFVVDITVWIDLSAAAASDDLAD
Mvan_5369|M.vanbaalenii_PYR-1       MTDRIELRGLKVRGNHGVFDHERRDGQDFIVDLTVWMELAAAAASDDLAD
MAB_0536|M.abscessus_ATCC_1997      MTDRIELRGLKVFGYHGVFEHERRDGQEFSVDITVWLDLDTAAATDQLAD
TH_0988|M.thermoresistible__bu      MADRIELRGLRVRGHHGVFDHERRDGQDFVVDITAWLDLTAAAGSDDLAD
MSMEG_6102|M.smegmatis_MC2_155      MADRIELRGLRVRGNHGVFDHERADGQDFVVDITVWMDLRPAAVSDDLAD
Rv3607c|M.tuberculosis_H37Rv        MADRIELRGLTVHGRHGVYDHERVAGQRFVIDVTVWIDLAEAANSDDLAD
Mb3637c|M.bovis_AF2122/97           MADRIELRGLTVHGRHGVYDHERVAGQRFVIDVTVWIDLAEAANSDDLAD
MMAR_5110|M.marinum_M               MADRIELRGLIVHGRHGVYDHERVAGQRFVVDITMWIDLADAARSDDLAD
MUL_4189|M.ulcerans_Agy99           MADRIELRDLIVHGRHGVYDHERVAGQRFVVDITMWIDLADGARSDDLAD
MLBr_00225|M.leprae_Br4923          MADRMELRGLIVRGRHGVYEVERANGQDFIVDVILWIDLADAAANDNLAD
MAV_0545|M.avium_104                MADRIELRGLRVRGQHGVFDHERVDGQDFVIDVTVWIDLVGAAASDELAD
                                    *:**:***.* * * ***:: **  ** * :*:  *::*  .* .*:***

Mflv_1419|M.gilvum_PYR-GCK          TLDYGVLAQRAADIVAGPPRQLIEAVAGEIADDVMRDERAHAVEVVVHKP
Mvan_5369|M.vanbaalenii_PYR-1       TLDYGVLAQRAADIVAGRPRQLIETVAAEIAEDVMRDARVHAVEVVVHKP
MAB_0536|M.abscessus_ATCC_1997      TLDYGDLAQRAAAIVSGPPRNLIESVAGAIAEDVMTDSRVHAVEAVVHKP
TH_0988|M.thermoresistible__bu      TLDYGALATRAADIVAGPPRNLIESVAGAIADDVMTDDRVDAVEVTVHKP
MSMEG_6102|M.smegmatis_MC2_155      TLDYGALAQRAADIVAGTPRNLIETVSAEIADGIMTDERLHAVEVVVHKP
Rv3607c|M.tuberculosis_H37Rv        TYDYVRLASRAAEIVAGPPRKLIETVGAEIADHVMDDQRVHAVEVAVHKP
Mb3637c|M.bovis_AF2122/97           TYDYVRLASRAAEIVAGPPRKLIETVGAEIADHVMDDQRVHAVEVAVHKP
MMAR_5110|M.marinum_M               TYDYAQLAQRAAEIVGGPPRNLIETVGAEIADEVMNDERVHAVEVVLHKP
MUL_4189|M.ulcerans_Agy99           TYDYAQLAQRAAEIVGGPPRNLIETVGAEIADEVMNDERVHAVEVVLHKP
MLBr_00225|M.leprae_Br4923          TYDYVVLAERTAAIIAGPPRNLIETVGSEIADFVMDDERVHAVEVVVHKP
MAV_0545|M.avium_104                TYDYAALAQLAADVVAGPARNLIETVGAQIADQVMDDERVHAVEVMVHKP
                                    * **  **  :* ::.* .*:***:*.. **: :* * * .***. :***

Mflv_1419|M.gilvum_PYR-GCK          SAPIPLQFNDVAVTARRSRRNAR----------
Mvan_5369|M.vanbaalenii_PYR-1       SAPIPLQFHDVAVTARRSRRGTAP---------
MAB_0536|M.abscessus_ATCC_1997      NAPIPLTFGDVAVVARRSRRSRSGAR-------
TH_0988|M.thermoresistible__bu      AAPIPLDFADVAVVVRRTRHGGRR---------
MSMEG_6102|M.smegmatis_MC2_155      SAPIPLTFDDVAVVARRSRRGGR----------
Rv3607c|M.tuberculosis_H37Rv        QAPIPQTFDDVAVVIRRSRRGGRGWVVPAGGAV
Mb3637c|M.bovis_AF2122/97           QAPIPQTFDDVAVVIRRSRRGGRGWVVPAGGAV
MMAR_5110|M.marinum_M               QAAIAQPLADVAVVTRRSRRGGRGSVIPADRAV
MUL_4189|M.ulcerans_Agy99           QAAIAQPLADVAVVTRRSRRGGRGSVIPADRAV
MLBr_00225|M.leprae_Br4923          QAPIPQQFSDVAVVVRRSRRGGRGSMIPASGV-
MAV_0545|M.avium_104                QAPIPQQFADVAVVVRRSRRGGRGSVVPAGGAL
                                     *.*.  : ****. **:*:.