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ERFDGLRPARLKVGIISAGRVGTALGVALQRADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAE LLLLAVTDSELAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMTFTGSDEDISR LPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDARILYHAALAHASNHIVTVLADALEALRAALSGG ELLGQQTVDDQPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALADVDAALAQAYR INALRTAQRAHAPADVVEVLTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3603c | - | - | 100% (303) | CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3633c | - | 1e-167 | 100.00% (303) | hypothetical protein Mb3633c |
| M. gilvum PYR-GCK | Mflv_1423 | - | 1e-124 | 76.85% (298) | NAD-dependent glycerol-3-phosphate dehydrogenase-like protein |
| M. leprae Br4923 | MLBr_00229 | - | 1e-106 | 67.85% (311) | hypothetical protein MLBr_00229 |
| M. abscessus ATCC 19977 | MAB_0540 | - | 1e-116 | 70.37% (297) | hypothetical protein MAB_0540 |
| M. marinum M | MMAR_5106 | - | 1e-148 | 88.41% (302) | hypothetical protein MMAR_5106 |
| M. avium 104 | MAV_0550 | - | 1e-145 | 88.04% (301) | chalcone/stilbene synthase family protein |
| M. smegmatis MC2 155 | MSMEG_6098 | - | 1e-130 | 77.52% (298) | chalcone/stilbene synthase family protein |
| M. thermoresistible (build 8) | TH_2352 | - | 1e-130 | 79.05% (296) | CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_4185 | - | 1e-149 | 89.07% (302) | hypothetical protein MUL_4185 |
| M. vanbaalenii PYR-1 | Mvan_5365 | - | 1e-123 | 74.50% (298) | NAD-dependent glycerol-3-phosphate dehydrogenase-like protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3603c|M.tuberculosis_H37Rv -------------------MERFDGLRPARLKVGIISAGRVGTALGVALQ
Mb3633c|M.bovis_AF2122/97 -------------------MERFDGLRPARLKVGIISAGRVGTALGVALQ
MMAR_5106|M.marinum_M --------------MRSSAMVQLDGLRPARLKVGIISAGRVGTALGVALE
MUL_4185|M.ulcerans_Agy99 -------------------MVQLDGLRPARLKVGIISAGRVGTALGVALE
Mflv_1423|M.gilvum_PYR-GCK -----MVQPSAGG------NSPHDGLRPARLTIGVISAGRVGTALGVALE
Mvan_5365|M.vanbaalenii_PYR-1 -----MVQPPAGG------DVPHDGFRPARLTIGVISAGRVGTAMGVALE
MSMEG_6098|M.smegmatis_MC2_155 -----MEQPPESG------WSPPDGLRPARLSVGIISAGRVGTALGYALE
MAB_0540|M.abscessus_ATCC_1997 MPEAFPVDGPVDGPVDDQSDGPLDGLRPARLAVGIISAGRVGTALGVALE
TH_2352|M.thermoresistible__bu -------------------MGAPNGLRPARLAVGIISAGRVGTALGVALE
MAV_0550|M.avium_104 -------------------MVQFDGLRPARLKVGIISAGRVGTALGVALE
MLBr_00229|M.leprae_Br4923 -------------------MVQFDGLRSARLNIAILSTGRVG----VALE
:*:*.*** :.::*:**** **:
Rv3603c|M.tuberculosis_H37Rv RADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAELLLLAVTDSE
Mb3633c|M.bovis_AF2122/97 RADHVVVACSAISHASRRRAQRRLPDTPVLPPLDVAASAELLLLAVTDSE
MMAR_5106|M.marinum_M RADHVVVACSAISHASLQRAQRRLPDTPVLPPPDVAASAELLVLAVTDSE
MUL_4185|M.ulcerans_Agy99 RADHVVVACSAISHASLQRAQRRLPDTPVLPPLDVAASAELLVLAVTDSE
Mflv_1423|M.gilvum_PYR-GCK RAEHVVVGCAAVSSASRARAARWLPDTPVLPVDEVARRAELLLLAVPDAE
Mvan_5365|M.vanbaalenii_PYR-1 RAEHVVVGCSAVSAASRDRARRWLPDTPILPVDEVARRAELLLLAVPDAE
MSMEG_6098|M.smegmatis_MC2_155 RVEHVVVACSAISHASRQRAERRLPDTAILPVHDVARRAELLLLSVPDAE
MAB_0540|M.abscessus_ATCC_1997 TAGHFVVACSAVSEASRRRAEQRLPESQILPAQEVAPRAELLILAVPDHE
TH_2352|M.thermoresistible__bu RVDHVVVACSAVSHASRRRAEERLPDTAVLPVPDVAARAELLLLAVPDTE
MAV_0550|M.avium_104 RADHVVVACSAISHASRQRAQRRLPDTPVATPPEVAAGAELLLLAVPDSE
MLBr_00229|M.leprae_Br4923 RADQVVVACSAVSHASRQWVQFRLPETSVASPPEVASSAELLLLAVPDCE
. :.**.*:*:* ** . **:: : . :** ****:*:*.* *
Rv3603c|M.tuberculosis_H37Rv LAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMT
Mb3633c|M.bovis_AF2122/97 LAGLVSGLAATSAVRPQTIVAHTSGANGIGILAPLAQQGCIPLAIHPAMT
MMAR_5106|M.marinum_M LAGLISGLAATSAVRPGAIVAHTSGANGIGILEPLTAQGCIPLAIHPAMT
MUL_4185|M.ulcerans_Agy99 LAGLISGLAATSAVRPGTIVAHTSGANGIGILEPLTAQGCIPLAIHPAMT
Mflv_1423|M.gilvum_PYR-GCK LSALVSGLATAGAVRPNTIVVHTSGANGIGVLAPLAALGCITLAIHPAMT
Mvan_5365|M.vanbaalenii_PYR-1 LSALVSGLAATGAVRPNTIVVHTSGANGIGVLAPLADRGCITLAIHPAMT
MSMEG_6098|M.smegmatis_MC2_155 LSGLVKGLATTGSVRPGTIVVHTSGANGVGILAPLTEQGCVPLAIHPAMT
MAB_0540|M.abscessus_ATCC_1997 LAALVAGLAATGSVRPGTIVVHTSGANGIAVLDPLTALGCMPLAIHPAMT
TH_2352|M.thermoresistible__bu LPGLVSGLAATEAVRPGTIVAHTSGANGIAVLAPLTEQGCTPLAIHPAMT
MAV_0550|M.avium_104 LAGLVSGLAATEAVRAGTIVAHTSGANGVGILAPLTRQGCIPLAIHPAMT
MLBr_00229|M.leprae_Br4923 FAGLMSGVAVTSVPRPGTIVAHTSWANGVGILAQLGKDGCIPLAIHPAMM
:..*: *:*.: *. :**.*** ***:.:* * ** .*******
Rv3603c|M.tuberculosis_H37Rv FTGSDEDISR--LPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDAR
Mb3633c|M.bovis_AF2122/97 FTGSDEDISR--LPDTCFGITAADDVGYAIGQSLVLEMGGEPFCVREDAR
MMAR_5106|M.marinum_M FTGSDEDINR--LPDTCFGITAADDVGYAIAQSLVLEMGGEPFCVREESR
MUL_4185|M.ulcerans_Agy99 FTGSDEDINR--LPDTCFGITAADDVGYAIAQSLVLEMGGEPFCVREESR
Mflv_1423|M.gilvum_PYR-GCK FAGTDEDVDR--LRGTCFGITAGDEIGYAIAQSLVLEVGGEPFRVREDAR
Mvan_5365|M.vanbaalenii_PYR-1 FVGTDEDVDR--LRGTCFGVTAGDDIGYAIAASLVLEIGGEPFRVREDAR
MSMEG_6098|M.smegmatis_MC2_155 FTGSDEDISR--LPDTCFGITAADEIGYAIGQSLVLEIGGEPFRVREDAR
MAB_0540|M.abscessus_ATCC_1997 FAGGDEDIER--LPNSCFGITAADEIGYAIGTALVLEIGGEPVRVREDAR
TH_2352|M.thermoresistible__bu FTGSDEDIER--LAGSCFGVTAADDVGYAVAQSLVLEIGGEPFRVAEDVR
MAV_0550|M.avium_104 FTGSDEDISR--LPDTCFGITAADEVGYAIAQSLVLEMGGEPFSVAEDAR
MLBr_00229|M.leprae_Br4923 FSGSDEDLSQCQLRDTYFGITKTDDVGYAIAQSLVLEMGGEPFCVVEYAR
* * ***:.: * .: **:* *::***:. :****:****. * * *
Rv3603c|M.tuberculosis_H37Rv ILYHAALAHASNHIVTVLADALEALRAALSGGELLGQ--------QTVDD
Mb3633c|M.bovis_AF2122/97 ILYHAALAHASNHIVTVLADALEALRAALSGGELLGQ--------QTVDD
MMAR_5106|M.marinum_M VLYHAALAHASNHLVTVLADALEALRTALRGQELLGQ--------QCVDN
MUL_4185|M.ulcerans_Agy99 VLYHAALAHASNHLVTVLADALEALRTALRGQELLGQ--------QCVDN
Mflv_1423|M.gilvum_PYR-GCK TLYHAALAHSSNHLVTVLLDAVDALRAALWGQELLGQ--------ELVGD
Mvan_5365|M.vanbaalenii_PYR-1 TLYHAALAHSSNHVVTVVLDAVDALRAALWGQELLGQ--------ELVGD
MSMEG_6098|M.smegmatis_MC2_155 AQYHAALAHGSNHLVTLVLDAVEALRSSLRGQELLGQ--------ELVGD
MAB_0540|M.abscessus_ATCC_1997 TLYHAALAHGSNHVVTLVLDAVEALRSALWGQELLGQ--------ETIGD
TH_2352|M.thermoresistible__bu PLYHAALAHAGNHVITVVLDAVEALRSALAGHELLGQ--------QLIDD
MAV_0550|M.avium_104 VLYHAALAHASNHLVTVLSDALEALRAALRGSELLGQ--------QTVDE
MLBr_00229|M.leprae_Br4923 ILYHSVSPHVGNHIVTVLADALEVRRSALRGSELLGLGVPPACRGEVVDD
**:. .* .**::*:: **::. *::* * **** : :.:
Rv3603c|M.tuberculosis_H37Rv QPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALAD
Mb3633c|M.bovis_AF2122/97 QPGGIVERIVGPLARAALENTLQRGQAALTGPVARGDAAAVADHLAALAD
MMAR_5106|M.marinum_M QPGGIAERIVGPLARAALENTLQRGQAALTGPVARGDAAAVAGHLAALTE
MUL_4185|M.ulcerans_Agy99 QPGGIAERIVGPLARAALENTLQRGQAALTGPVARGDAAAVAGHLAALTE
Mflv_1423|M.gilvum_PYR-GCK APGGIAERIVGPLARAALENALQRGQAALTGPVARGDAAAVAAHLQALAE
Mvan_5365|M.vanbaalenii_PYR-1 VPGGLPERIIGPLARAALDNALRRGQAALTGPVARGDAAAVAGHLQALRE
MSMEG_6098|M.smegmatis_MC2_155 EPGGLAERVIAPLARAALENALQRGQSALTGPVARGDAAAVAAHLTALAE
MAB_0540|M.abscessus_ATCC_1997 GPGGLPERVLAPLVRAAVTNALDRGQAALTGPVARGDGAAIGRHLDALME
TH_2352|M.thermoresistible__bu APGGLAERVVGPLARASLENALQRGQAALTGPVARGDGAAVARHLRALAD
MAV_0550|M.avium_104 QPGGIAERIVGPLARAALENTLQRGQAALTGPVARGDAAAVAGHLAALHR
MLBr_00229|M.leprae_Br4923 QLDVIVERIVGSLARAACENTLQRGQAGLTKLVARGDLDALAGHLVALMR
. : **::..*.**: *:* ***:.** ***** *:. ** **
Rv3603c|M.tuberculosis_H37Rv VDAALAQAYRINALRTAQRAHAPADVVEVLTA----
Mb3633c|M.bovis_AF2122/97 VDAALAQAYRINALRTAQRAHAPADVVEVLTA----
MMAR_5106|M.marinum_M ADPQLAQAYRVNALRTAMRAHAPGDVVEVLTP----
MUL_4185|M.ulcerans_Agy99 ADPQLAQAYRVNALRTAMRAHAPGDVVEVLTP----
Mflv_1423|M.gilvum_PYR-GCK VNPDLAQAYRADSWRTAQRAHAPAAVFDVLTETGQ-
Mvan_5365|M.vanbaalenii_PYR-1 VNPDLAQAYRTNSWRTAQRAHAPQEVLEVLSEAGQS
MSMEG_6098|M.smegmatis_MC2_155 VEPQLAQSYRANSLRTAQRAHAPEAVFEVLSEASRG
MAB_0540|M.abscessus_ATCC_1997 ADPALADAYRADARRTAQRAHAPQSVFSALEPRDAG
TH_2352|M.thermoresistible__bu VDPQLAQAYRCNSLRTAQRARAPEEVFAVFAEEGQP
MAV_0550|M.avium_104 VAPELAQAYRVNALRTAQRAHAPQEVVEVLAP----
MLBr_00229|M.leprae_Br4923 IGPELAQAYRVNALRKTQRAHAPYDVVEALAP----
. **::** :: *.: **:** *. .: