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M. tuberculosis H37Rv Rv3566c (nat)

annotation: ARYLAMINE N-ACETYLTRANSFERASE NAT (ARYLAMINE ACETYLASE)
coordinates: 4007331 - 4008182
length: 283

ALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLGVPVDDLSPQALADKLVLRRRGGYCF
EHNGLMGYVLAELGYRVRRFAARVVWKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRL
ETGAVQPTTHEPYRLEDRVDGFVLQAMVRDTWQTLYEFTTQTRPQIDLKVASWYASTHPASKFVTGLTAA
VITDDARWNLSGRDLAVHRAGGTEKIRLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGAD
AP*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3566cnat-100% (283)ARYLAMINE N-ACETYLTRANSFERASE NAT (ARYLAMINE ACETYLASE)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3596cnat1e-165100.00% (283) arylamine n-acetyltransferase nat (arylamine acetylase)
M. gilvum PYR-GCKMflv_0433-9e-9160.82% (268) arylamine N-acetyltransferase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0013c-3e-2332.95% (264) arylamine n-acetyl transferase
M. marinum MMMAR_5055nat1e-12276.56% (273) arylamine N-acetyltransferase Nat
M. avium 104MAV_0595-1e-10668.25% (274) arylamine N-acetyltransferase
M. smegmatis MC2 155MSMEG_0306-1e-9360.95% (274) arylamine N-acetyltransferase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4131nat1e-12376.56% (273) arylamine N-acetyltransferase Nat
M. vanbaalenii PYR-1Mvan_0235-3e-8959.63% (270) arylamine N-acetyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Rv3566c|M.tuberculosis_H37Rv        ----MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLG
Mb3596c|M.bovis_AF2122/97           ----MALDLTAYFDRINYRGATDPTLDVLQDLVTVHSRTIPFENLDPLLG
MMAR_5055|M.marinum_M               ----MALDLTGYLDRINYRGATDPTLDVLRDLVSAHTGAIAFENLDPLMG
MUL_4131|M.ulcerans_Agy99           ----MALDLTGYLDRINYRGATDPTLDVLRDLVSAHTGAIAFENLDPLMG
MAV_0595|M.avium_104                ----MTLDLGAYFDRIGYGGKAAPNLEVLRALMAAHTGSIPFENLDPLMG
Mflv_0433|M.gilvum_PYR-GCK          ----MSRLSDAYLSRIGFSGPAAATVDTLRRIVAAHNAAIPFENLDPLMG
Mvan_0235|M.vanbaalenii_PYR-1       -MADMPTLLDAYFTRIGLTMPVESTLDALRDIVAGHNRSIPFENLDPVTG
MSMEG_0306|M.smegmatis_MC2_155      -MAGMAMDLSGYLARIGLDGRPRPDLGTLHAIVAAHNRSIPFENLDPLLG
MAB_0013c|M.abscessus_ATCC_199      MWNGDELQLDEYLAFIGFDGDRSPTLETLRRLQRGHVLNIKWENLDAVLH
                                               *:  *.      . : .*: :   *   * :****.:  

Rv3566c|M.tuberculosis_H37Rv        VPVDDLSPQALADKLVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVV
Mb3596c|M.bovis_AF2122/97           VPVDDLSPQALADKLVLRRRGGYCFEHNGLMGYVLAELGYRVRRFAARVV
MMAR_5055|M.marinum_M               VPVDDLSAEALADKLVDRRRGGYCYEHNGLIGYVLAELGYRVRRLAGRVV
MUL_4131|M.ulcerans_Agy99           VPVDDVSPEALADKLVDRRRGGYCYEHNGLIGYVLAELGYRVRRLAGRVV
MAV_0595|M.avium_104                VPVDDLSPAALTDKLVHRRRGGYCYEQNGLLGYALAEIGFRVRRLAGRVV
Mflv_0433|M.gilvum_PYR-GCK          VPVVDLSAEALSDKLIGRRRGGYCYEHNGLLGYVLEDLGYAVERLVGRVV
Mvan_0235|M.vanbaalenii_PYR-1       IPVVDLSAEALADKLLGRRRGGYCYEQNGLLGYVLDDLGFGVQRLVGRVI
MSMEG_0306|M.smegmatis_MC2_155      IPVADLSAEALSAKLVDRRRGGYCYEHNGLLGYVLEELGFDVERLSGRVV
MAB_0013c|M.abscessus_ATCC_199      KHVA-LDIPAVQAKLLRSPRGGYCYEHVALFGAVLQRLGFDFYGIQGRVQ
                                      *  :.  *:  **:   *****:*: .*:* .*  :*: .  : .** 

Rv3566c|M.tuberculosis_H37Rv        WKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRLETGAV
Mb3596c|M.bovis_AF2122/97           WKLAPDAPLPPQTHTLLGVTFPGSGGCYLVDVGFGGQTPTSPLRLETGAV
MMAR_5055|M.marinum_M               WLAPPDAPTPAQTHTVLAVTFPGCQGPYLVDVGFGGMTPTAPLRLETGTV
MUL_4131|M.ulcerans_Agy99           WLAPPDAPTPAQTHTVLAVTFPGCQGPYLVDVGFGGMTPTAPLRLETGTV
MAV_0595|M.avium_104                WMQPPDTPPRAQTHTVLAVTFPGSQGAYLVDVGFGGQTLPSPIRFETGNS
Mflv_0433|M.gilvum_PYR-GCK          WMHEGDA-LPAQTHQVLAVTLPDGYGPWLVDVGFGGQTLTSPIRLQTGVV
Mvan_0235|M.vanbaalenii_PYR-1       WMHDDDT-LPAQTHQVLSVTLPDGDGPYLVDVGFGGQTLSSPIRLAPGQV
MSMEG_0306|M.smegmatis_MC2_155      WMRADDAPLPAQTHNVLSVAVPGADGRYLVDVGFGGQTLTSPIRLEAGPV
MAB_0013c|M.abscessus_ATCC_199      MG---ATTIRPATHGMLVVRLAAEQ--WLCDVGFG-TSPLAPIRLVDEAV
                                          :   . ** :* * ..     :* *****  :  :*:*:     

Rv3566c|M.tuberculosis_H37Rv        QPTTHEPYRLEDR-----VDGFVLQAMVRD----TWQTLYEFTTQTRPQI
Mb3596c|M.bovis_AF2122/97           QPTTHEPYRLEDR-----VDGFVLQAMVRD----TWQTLYEFTTQTRPQI
MMAR_5055|M.marinum_M               QQTALEPYRLDDR-----GDGLVLQAMVRD----EWQALYEFSTLTRPQV
MUL_4131|M.ulcerans_Agy99           QQTALEPYRLDDR-----GDGLVLQAMVRD----EWQALYEFSTLTRPQV
MAV_0595|M.avium_104                QQTTHEPYRLDDR-----GEGLVLQALVRD----EWQPLYVFGTRTVPQI
Mflv_0433|M.gilvum_PYR-GCK          AQTRHEPYRLLDH-----ADGMQLQALIRD----VWQPLYLLDPAPRPRI
Mvan_0235|M.vanbaalenii_PYR-1       QQTRHEPYRLLDH-----PEGFELQARVGG----VWESLYLLDPIPRPRI
MSMEG_0306|M.smegmatis_MC2_155      QQTRHEPYRLTRR-----GDHHTLAAQIRG----EWQPLYTFTTEPRPRI
MAB_0013c|M.abscessus_ATCC_199      VADESWTYRLRRGEVTPGADGWTLSEAAGDGSEPGWLSRHTFVLEPQYPI
                                          .***         :   *     .     * . : :   .   :

Rv3566c|M.tuberculosis_H37Rv        DLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKI
Mb3596c|M.bovis_AF2122/97           DLKVASWYASTHPASKFVTGLTAAVITDDARWNLSGRDLAVHRAGGTEKI
MMAR_5055|M.marinum_M               DLRVGSWFVSTHPTSHFVTGLMAATVADDARWNLMGRNLAIHRRGGTEKI
MUL_4131|M.ulcerans_Agy99           DLRVGSWFVSTHPTSHFVTGLMAATVADDARWNLMGRNLAIHRRGGTEKI
MAV_0595|M.avium_104                DLLVGSWYVSTHPSSMFVTGLMVALTTADARWNLAGRELTVHRAQGSEKI
Mflv_0433|M.gilvum_PYR-GCK          DLEVGSWYVSTFPRSGFVTGLTAALVTDDARWNLRGRHLAVHRAGGTEKT
Mvan_0235|M.vanbaalenii_PYR-1       DLEVGSWYVSTYPESVFVRGLTAALVTDDARWNLRGRRLAVHRAGGSEKT
MSMEG_0306|M.smegmatis_MC2_155      DLEVGSWYVSTHPGSHFVTGLTVAVVTDDARYNLRGRNLAVHRSGATERI
MAB_0013c|M.abscessus_ATCC_199      DYRAASYFVASSPHSPFSTRAFVQQISPDHAYILDHRELHEIQPGVGRKT
                                    *  ..*::.:: * * *     .   : *  : *  * *   :    .: 

Rv3566c|M.tuberculosis_H37Rv        RLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP
Mb3596c|M.bovis_AF2122/97           RLADAAAVVDTLSERFGINVADIGERGALETRIDELLARQPGADAP
MMAR_5055|M.marinum_M               LLEDAAAVVDTLGDRFGINVADVGERGRLEARIDKVCF---GAENR
MUL_4131|M.ulcerans_Agy99           LLEDAAAVVDTLGDRFGINVADVGERGRLEARIDKVCF---GAEDR
MAV_0595|M.avium_104                RLDDADAVLDVLGERFGIDVDGIGQRGALLARIEQVLDA-------
Mflv_0433|M.gilvum_PYR-GCK          RLDTAAEVMELLATRFGIDLDDLGNRADVASRITAVLDT-------
Mvan_0235|M.vanbaalenii_PYR-1       RLGSAADVLEVLEGRFGINLADLGDRAELEARVGRVLDS-------
MSMEG_0306|M.smegmatis_MC2_155      RFDSAAQVLDAIVNRFGIDLGDLAGR-DVQARVAEVLDT-------
MAB_0013c|M.abscessus_ATCC_199      RQLTPAEVLATLREIFGIELGADDSTLLLERLAEQ-----------
                                        .  *:  :   ***::        :