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M. tuberculosis H37Rv Rv3470c (ilvB2)

annotation: PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB2 (AHAS) (ACETOHYDROXY-ACID SYNTHASE LARGE SUBUNIT) (ALS)
coordinates: 3887144 - 3888802
length: 552

TVGDHLVARMRAAGISVVCGLPTSRLDSLLVRLSRDAGFQIVLARHEGGAGYLADGFARASGKSAAVFVA
GPGATNVISAVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFRRFCRCSVSIESIANARS
KIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGTAAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPM
LVLGNGCRLDGIGEQIVAFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDLLIA
VGVSFGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTSGRAFVNALNCGRPPRFCRRVGVR
PPAPAALPGTPQARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFATVDFSPMG
CGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGIRVTWAVLNDGQMSASAGPVSGRMDPSPV
ARIGANDLAAMARALGAEGIRVDTRCELRAGVQKALAATGPCVLDIAIDPEINKPDIGLGR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3470cilvB2-100% (552)PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB2 (AHAS) (ACETOHYDROXY-ACID SYNTHASE LARGE SUBUNIT) (ALS)
M. tuberculosis H37RvRv3003cilvB11e-3926.37% (565) acetolactate synthase 1 catalytic subunit
M. tuberculosis H37RvRv1820ilvG1e-3826.69% (562) hypothetical protein Rv1820

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3499cilvB20.099.82% (552) acetolactate synthase large subunit
M. gilvum PYR-GCKMflv_4239-3e-4026.00% (577) acetolactate synthase 1 catalytic subunit
M. leprae Br4923MLBr_01696ilvB6e-3926.05% (572) acetolactate synthase 1 catalytic subunit
M. abscessus ATCC 19977MAB_3323c-7e-4025.88% (568) acetolactate synthase 1 catalytic subunit
M. marinum MMMAR_1710ilvB12e-3925.84% (565) acetolactate synthase (large subunit) IlvB1
M. avium 104MAV_4935-4e-3725.41% (547) acetolactate synthase
M. smegmatis MC2 155MSMEG_5593-2e-3726.63% (567) pyruvate dehydrogenase
M. thermoresistible (build 8)TH_2440-3e-4026.01% (569) PUTATIVE acetolactate synthase, large subunit
M. ulcerans Agy99MUL_1947ilvB12e-4026.02% (565) acetolactate synthase 1 catalytic subunit
M. vanbaalenii PYR-1Mvan_2122-2e-3826.25% (579) acetolactate synthase 1 catalytic subunit

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4239|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_2122|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2440|M.thermoresistible__bu      --------------------------------------------------
MMAR_1710|M.marinum_M               --------------------------------------------------
MUL_1947|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01696|M.leprae_Br4923          --------------------------------------------------
MAB_3323c|M.abscessus_ATCC_199      --------------------------------------------------
Rv3470c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3499c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4935|M.avium_104                --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155      MTVEEAGQELEWHRVADHDELDEGQVSACPAGRKTVALTKLNGRYGAIDN
                                                                                      

Mflv_4239|M.gilvum_PYR-GCK          ---------------MSAPTKRPPE-----QSETPTNGTAAAAKYN-SAT
Mvan_2122|M.vanbaalenii_PYR-1       ---------------MSAPTKRPPE-----QSATPTDGTAAAAKHN-SAP
TH_2440|M.thermoresistible__bu      ---------------VSAPTTRTAE-----RAAPHANGAAGTAAPEPTNP
MMAR_1710|M.marinum_M               ---------------MSAPTKRHSP-----TSEPQPRGVAAGVNS-----
MUL_1947|M.ulcerans_Agy99           ---------------MSAPTKRHSP-----TSEPQPRGVAAGVNS-----
MLBr_01696|M.leprae_Br4923          ---------------MSAPTKPHARPQGAGNSVPNTVKPATQFPSK----
MAB_3323c|M.abscessus_ATCC_199      ---------------MSAPAKPKPA-----SASGRAPGTAPE--------
Rv3470c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb3499c|M.bovis_AF2122/97           --------------------------------------------------
MAV_4935|M.avium_104                --------------------------------------------------
MSMEG_5593|M.smegmatis_MC2_155      RCPHQGGPLGQGTLENDKIRCPWHGFDFDPFTGEAAGGPDFNVTTYPVDV
                                                                                      

Mflv_4239|M.gilvum_PYR-GCK          T----QAQPNVVAPHQLTGAQAVIRSLEELGVDVIFGIPGGAVLPVYDPL
Mvan_2122|M.vanbaalenii_PYR-1       APSQATRQPNNIAPQQLTGAQAVIRSLEELGVDVIFGIPGGAVLPVYDPL
TH_2440|M.thermoresistible__bu      PAKPASAGQKRIAPHQLTGAQAVIRALEELDVDVIFGIPGGAVLPVYDPL
MMAR_1710|M.marinum_M               ----SPVHSKHVAPEQLTGAQSVIRSLEELDVEIIFGIPGGAVLPVYDPL
MUL_1947|M.ulcerans_Agy99           ----SLVHSKHVAPEQLTGAQSVIRSLEELDVEIIFGIPGGAVLPVYDPL
MLBr_01696|M.leprae_Br4923          ---PAVAKLERVSPEQLTGAQSVIRSLEELDVEVIFGIPGGAVLLVYDPL
MAB_3323c|M.abscessus_ATCC_199      --------PNTVAPQRVTGAQSVVRSLEELGVEVIFGIPGGAVLPVYDPL
Rv3470c|M.tuberculosis_H37Rv        ----------------MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRL
Mb3499c|M.bovis_AF2122/97           ----------------MTVGDHLVARMRAAGISVVCGLPTSRLDSLLVRL
MAV_4935|M.avium_104                ---------------MSKAAELIVKCLENEGVSVVFGLPGEENIRFVQAL
MSMEG_5593|M.smegmatis_MC2_155      RDDGIYVGAPPPAPAARTVSDVLVETMTNWGVDTVFGMVGHSNLGLAEAM
                                                     . .: ::  :   .:. : *:       .   :

Mflv_4239|M.gilvum_PYR-GCK          F---DSQKLRHVLVRHEQGGGHAASGYAHATGRVGVCMATSGPGATNLVT
Mvan_2122|M.vanbaalenii_PYR-1       F---DSKKLRHVLVRHEQGGGHAASGYAHATGRVGVCMATSGPGATNLVT
TH_2440|M.thermoresistible__bu      F---DSKKLRHVLVRHEQGAGHAASGYAHATGRVGVCMATSGPGATNLVT
MMAR_1710|M.marinum_M               F---DSQKLRHVLVRHEQGAGHAASGYAHATGKVGVCMATSGPGATNLVT
MUL_1947|M.ulcerans_Agy99           F---DSQKLRHVLVRHEQGAGHAASGYAHATGKVGVCMATSGPGATNLVT
MLBr_01696|M.leprae_Br4923          F---YSKKLRHVLVRHEQGAGHAASGYAHVTGKVGVCMATSGPGATNLVT
MAB_3323c|M.abscessus_ATCC_199      Y---DSTKVRHVLVRHEQGAGHAASGYAHANGKVGVMMATSGPGATNLVT
Rv3470c|M.tuberculosis_H37Rv        S---RDAGFQIVLARHEGGAGYLADGFARASGKS-AAVFVAGPGATNVIS
Mb3499c|M.bovis_AF2122/97           S---RDAGFQIVLARHEGGAGYLADGFARASGKS-AAVFVAGPGATNVIS
MAV_4935|M.avium_104                A---ASP-IRYVLTRHEQAASFMAEMYGRVTGRAAVVSATLGPGAINMQL
MSMEG_5593|M.smegmatis_MC2_155      HRAENAGKLRYFGIRHEGAAAFAASAYGKLTGRPAACFGIAGPGSTNLLT
                                            .: .  *** .... *. :.: .*:  .     ***: *:  

Mflv_4239|M.gilvum_PYR-GCK          PLADAYMDSIPMVAITGQVGRALIGTDAFQEADISGITMPVTKH--NFL-
Mvan_2122|M.vanbaalenii_PYR-1       PLADAYMDSIPMVAITGQVGRALIGTDAFQEADISGITMPVTKH--NFL-
TH_2440|M.thermoresistible__bu      PLADAHMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKH--NFL-
MMAR_1710|M.marinum_M               PLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKH--NFL-
MUL_1947|M.ulcerans_Agy99           PLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKH--NFL-
MLBr_01696|M.leprae_Br4923          PLADAQMDSVPVVAITGQVGRSLIGTDAFQEADISGITMPITKH--NFL-
MAB_3323c|M.abscessus_ATCC_199      PLADAQMDSIPVVAITGQVGRGLIGTDAFQEADISGITMPITKH--NFL-
Rv3470c|M.tuberculosis_H37Rv        AVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFR--RFCR
Mb3499c|M.bovis_AF2122/97           AVANASVNQVPMLILTGEVAVGEFGLHSQQDTSDDGLGLGATFR--RFCR
MAV_4935|M.avium_104                GVADATTNSTPLVAISAQVGHDREFKESHQYVDLVSMFAPITRWAAG---
MSMEG_5593|M.smegmatis_MC2_155      GLYDAKADRAPVLALSGNVESAVAGKGAFQDIDLLAAFADVAVYS-----
                                     : :*  :  *:: ::.:*        : *  .  .     :        

Mflv_4239|M.gilvum_PYR-GCK          ----VRDGDDIARVIAEAFHIAASGRPGPVLVDIPKDVLQGQCTFAWP--
Mvan_2122|M.vanbaalenii_PYR-1       ----VRDGDDIARVIAEAFHIASSGRPGPVLVDIPKDILQGECTFAWP--
TH_2440|M.thermoresistible__bu      ----VRDGDDIPRILAEAFHIASSGRPGPVLVDIPKDILQGQCTFSWP--
MMAR_1710|M.marinum_M               ----VRTGDDIPRVLAEAFHIAASGRPGAVLVDIPKDVLQAQCTFSWP--
MUL_1947|M.ulcerans_Agy99           ----VRTGDDIPRVLAEAFHIAASGRPGAVLVDIPKDVLQAQCTFSWP--
MLBr_01696|M.leprae_Br4923          ----VRAGDDIPRVLAEAFHIASSGRPGAVLVDIPKDVLQGQCKFSWP--
MAB_3323c|M.abscessus_ATCC_199      ----VSNAEDIPKVIAEAFYIAQSGRPGAVLVDIPKDILQAQTTFSWP--
Rv3470c|M.tuberculosis_H37Rv        CSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGT
Mb3499c|M.bovis_AF2122/97           CSVSIESIANARSKIDSAFRALASIPRGPVHIALPRDLVDERLPAHQLGT
MAV_4935|M.avium_104                ----IPTARAIPEMVRKAFKLAESERPAAVYLAVPEHIDADETDYDLG--
MSMEG_5593|M.smegmatis_MC2_155      --EMVRDGSEHAELMTMALKHAILER-GVAHLVVPDEVQVIQSDRRSS--
                                        :         :  *:        . . : :* .:   .        

Mflv_4239|M.gilvum_PYR-GCK          PQFELPGYKPNTKPHNRQIREAAKLIAESRKPVLYVGGGVIRGEASEQLL
Mvan_2122|M.vanbaalenii_PYR-1       PQFELPGYKPNTKPHNRQIREAAKLIGEASKPVLYVGGGVIRGEASEQLL
TH_2440|M.thermoresistible__bu      PRFELPGYKPNTKPHSRQIREAAKLIAAARKPVLYVGGGVIRGAAGEELR
MMAR_1710|M.marinum_M               PQMDLPGYKPNTKPHNRQIREAAKLIGAARKPVLYVGGGVIRGEATEQLA
MUL_1947|M.ulcerans_Agy99           PQMDLPGYKPNTKPHNRQIREAAKLIGAARKPVLYVGGGVIRGEATEQLA
MLBr_01696|M.leprae_Br4923          PKMDLPGYKPNTKPHNRQIRAAAKLIADARKPVLYVGGGVIRGEATEQLR
MAB_3323c|M.abscessus_ATCC_199      PQIYLPGYKPVTKPHGKQVREAVRLIAAAKRPVLYVGGGVIRADASPELK
Rv3470c|M.tuberculosis_H37Rv        AAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIV
Mb3499c|M.bovis_AF2122/97           AAAGLGGLRTLAPCGPDVADEVIGRLDRSRAPMLVLGNGCRLDGIGEQIV
MAV_4935|M.avium_104                --PLPRNVVRPDAPSPRQVERAAQILRNAKRPVVLAGHGAARADATKALV
MSMEG_5593|M.smegmatis_MC2_155      -GPEGRMPDLRVAPPSTPLERALDRIAAATRPAVIVGAGAKFDMA--AIV
                                                         .   :  :  * :  * *         : 

Mflv_4239|M.gilvum_PYR-GCK          DLAELTGIPVVTTLMARGAFPDSHPQNLGMPGMHGTVAAVAALQRS--DL
Mvan_2122|M.vanbaalenii_PYR-1       DLAELTGIPVVTTLMARGAFPDSHPQNLGMPGMHGTVAAVAALQRS--DL
TH_2440|M.thermoresistible__bu      ELAELTGIPVVTTLMARGAFPDSHPQNLGMPGMHGTVAAVAAMQKS--DL
MMAR_1710|M.marinum_M               ELAELTGIPVVTTLMARGAFPDSHRQNMGMPGMHGTVAAVAALQRS--DL
MUL_1947|M.ulcerans_Agy99           ELAELTGIPVVTTLMARGAFPDSHRQNMGMPGMHGTVAAVAALQRS--DL
MLBr_01696|M.leprae_Br4923          DLAELTGIPVVSTLMARGAFPDSHHQNLGMPGMHGTVAAVAALQRS--DL
MAB_3323c|M.abscessus_ATCC_199      ELAELTGIPVVTTLMARGAFPDSHELHMGMPGMHGTVGAVAALQRS--DL
Rv3470c|M.tuberculosis_H37Rv        AFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDL
Mb3499c|M.bovis_AF2122/97           AFCEKAGLPFATTPNGRGIVAETHPLSLGVLGIFGDGRADEYLFDTPCDL
MAV_4935|M.avium_104                RFSEEFGIQVANTFHGKGVMPDDHPNSIGTLGFMRHDYVNFGFDHA--DA
MSMEG_5593|M.smegmatis_MC2_155      ALAERLHAPVLTTFKAKGQIADDHPLACGALGRSGTPVASWMMNKA--DL
                                     :.*     . .*  .:* ..: *    *  *      .   :  :  * 

Mflv_4239|M.gilvum_PYR-GCK          LIALGTRFDDRVTGKLDS--FAPEAKVIHADIDPAEIGKNRHADVPIVGD
Mvan_2122|M.vanbaalenii_PYR-1       LIALGTRFDDRVTGKLDS--FAPEAKVIHADIDPAEIGKNRHADVPIVGD
TH_2440|M.thermoresistible__bu      LIALGTRFDDRVTGQLDS--FAPEAKVIHADIDPAEIGKNRHADVPIVGD
MMAR_1710|M.marinum_M               LIALGTRFDDRVTGKLDS--FAPEAKVIHADIDPAEIGKNRNADVPIVGD
MUL_1947|M.ulcerans_Agy99           LIALGSRFDDRVTGKLDS--FAPEAKVIHADIDPAEIGKNRNADVPIVGD
MLBr_01696|M.leprae_Br4923          LIALGTRFDDRVTGKLDS--FAPDAKVIHADIDPAEIGKNRHADVPIVGD
MAB_3323c|M.abscessus_ATCC_199      LITLGARFDDRVTGQLDS--FAPEAKVIHADIDPAEIGKNRHADVPIVGD
Rv3470c|M.tuberculosis_H37Rv        LIAVGVSFGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTS
Mb3499c|M.bovis_AF2122/97           LIAVGVSFGGLVTRSFSPRWRGLKADVVHVDPDPSAVGRFVATSLGITTS
MAV_4935|M.avium_104                VIAVGYELQEFDPVRINP---QADKKIIHMHRFPAEVDAHYSVDVGIIGD
MSMEG_5593|M.smegmatis_MC2_155      LVVFGASFSNHTG-------ISPYKPVIQVDTDPLVLGRFNPVAVPVLGD
                                    ::..*  :                  ::: .  *  :.    . : :  .

Mflv_4239|M.gilvum_PYR-GCK          VKNVIADLIEVLRRDGQ-GAVEL--DAWWESLRGIQATFPLSYG----PQ
Mvan_2122|M.vanbaalenii_PYR-1       VKAVITDLIEVLRRDGATASTKL--DNWWEYLRGIESTYPLSYG----PQ
TH_2440|M.thermoresistible__bu      VKAVIADLLAVLRRDGVADSIKI--DGWWEYLRGVQQTYPLSYG----PQ
MMAR_1710|M.marinum_M               VQAVITELIAMLRHYDIPGNIEM--SEWLAYLEGVRATYPLSYG----PQ
MUL_1947|M.ulcerans_Agy99           VQAVITELIAMLRHYDIPGNIEM--SEWLAYLEGVRAPYPLSYG----PQ
MLBr_01696|M.leprae_Br4923          VKAVIVELIAMLRHYEVPGNIEM--TDWWSYLDGVRKTYPLSYS----PQ
MAB_3323c|M.abscessus_ATCC_199      VKNVIIELIEAIRADRAAGTVADPLSEWWEYLSDVRKTYPLGYD----AQ
Rv3470c|M.tuberculosis_H37Rv        GRAFVNALNCGR-------------PPRFCRRVGVRPPAPAALPGT--PQ
Mb3499c|M.bovis_AF2122/97           GRAFVNALNCGR-------------PPRFCRRVGVRPPAPAALPGT--PQ
MAV_4935|M.avium_104                ISDSLNALTDALS------------GHRFEHAADVPGSGLLTDEFARGQQ
MSMEG_5593|M.smegmatis_MC2_155      VGVTASALTQRLRTHPDLVDQRAEIAERWSVWRTEKARRATKQP------
                                           *                                          

Mflv_4239|M.gilvum_PYR-GCK          SDG-SLSPEFVIETLGKMAGPDAVYVAGVGQHQMWAAQFISYEKPKTWLN
Mvan_2122|M.vanbaalenii_PYR-1       SDG-SLSPEFVIETLGKIAGSDAVYVAGVGQHQMWAAQFISYENPKTWIN
TH_2440|M.thermoresistible__bu      SDG-SLSPEYVIETLGKMAGPDAIYVAGVGQHQMWAAQFISYEKPQTWIN
MMAR_1710|M.marinum_M               SDG-SLGPEYVIEKLGEIAGPDAIYVAGVGQHQMWAAQFIKYEKPRTWLN
MUL_1947|M.ulcerans_Agy99           SDG-SLGPEYVIEKLGEIAGPDAIYVAGVGQHQMWAAQFIKYEKPRTWLN
MLBr_01696|M.leprae_Br4923          SDG-TLSPEYVIEKLGEIVGPEAVYVAGVGQHQMWAAQFISYEKPRTWLN
MAB_3323c|M.abscessus_ATCC_199      HDG-SLGPEFVIETLGKIAGPDAVYVAGVGQHQMWAAQFIKYENPRTWLN
Rv3470c|M.tuberculosis_H37Rv        ARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFA
Mb3499c|M.bovis_AF2122/97           ARGESIHPLELMHELDRELAPNATICADVGTCISWTFRGIPVRRPGRFFA
MAV_4935|M.avium_104                DSRYPLAPARVVADTRAALGRSDVVLVDTGATKMWMARLYPTYERNTCLI
MSMEG_5593|M.smegmatis_MC2_155      --GGRIAAATVFDELGRLVPAGAVLTVDVGNHAYSFGRYFETKDEQTVLM
                                         : .  :.              ...*       :          : 

Mflv_4239|M.gilvum_PYR-GCK          SGGLGTMGFAVPAAMGAKMGRPEAEVWAIDGDGCFQMTNQELATCAIEGV
Mvan_2122|M.vanbaalenii_PYR-1       SGGLGTMGFAVPAAMGAKMGRPEAEVWAIDGDGCFQMTNQELATCAIEGV
TH_2440|M.thermoresistible__bu      SGGLGTMGFAVPAAMGAKMGRPDAEVWAIDGDGCFQMTNQELATCAVEGV
MMAR_1710|M.marinum_M               SGGLGTMGFAIPAAMGAKIALPDTEVWAIDGDGCFQMTNQELATCAIEGI
MUL_1947|M.ulcerans_Agy99           SGGLGTMGFAIPAAMGAKIALPDTEVWAIDGDGCFQMTNQELATCAIEGI
MLBr_01696|M.leprae_Br4923          SGGLGTMGFAIPAAMGAKIARPEAEVWAIDGDGCFQMTNQELATCAIEGA
MAB_3323c|M.abscessus_ATCC_199      SGGLGTMGFAVPAAMGAKMARPEAEVWAIDGDGCFQMTNQELATCAIEGV
Rv3470c|M.tuberculosis_H37Rv        TVDFSPMGCGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGI
Mb3499c|M.bovis_AF2122/97           TVDFSPMECGIAGAIGVALARPEEHVICIAGDGAFLMHGTEISTAVAHGI
MAV_4935|M.avium_104                SNGLSTMSFALPGALGVKLAQPQSKVLAVVGDGAFLMNSQEIETAVRERI
MSMEG_5593|M.smegmatis_MC2_155      SGYLGSIGFGFPAAMGAWAAAPDRPIVAVTGDGGFGQYLADFTTAVKYGM
                                    :  :..:  ....*:*.  . *:  : .: *** *     :: *..    

Mflv_4239|M.gilvum_PYR-GCK          PIKVALINNGNLGMVRQWQTLFYEERYSQTDLATHTRRIPDFVKLAEALG
Mvan_2122|M.vanbaalenii_PYR-1       PIKVALINNGNLGMVRQWQTLFYEERYSQTDLATHSRRIPDFVKLSEALG
TH_2440|M.thermoresistible__bu      PIKVALINNGNLGMVRQWQTLFYEERYSQTDLATHTQRIPDFVKLAEALG
MMAR_1710|M.marinum_M               PIKVALINNGNLGMVRQWQNLFYEERYSQTDLATHSHRIPDFVKLAEALG
MUL_1947|M.ulcerans_Agy99           PIKVALINNGNLGMVRQWQNLFYEERYSQTDLATHSHRIPDFVKLAEALG
MLBr_01696|M.leprae_Br4923          PIKVALINNGNLGMVRQWQALFYQERYSQTDLATHSHRIPDFVKLAEALG
MAB_3323c|M.abscessus_ATCC_199      PIKVALINNGNLGMVRQWQTLFYEERYSQTDLATHSRRIPDFVKLAEALG
Rv3470c|M.tuberculosis_H37Rv        RVTWAVLNDGQMSAS----AGPVSGRMDPSPVARIG--ANDLAAMARALG
Mb3499c|M.bovis_AF2122/97           RVTWAVLNDGQMSAS----AGPVSGRMDPSPVARIG--ANDLAAMARALG
MAV_4935|M.avium_104                PLVVLIWEDGGYGLIEWKMDLELGAHYYVK------FANPDVVTYAESFG
MSMEG_5593|M.smegmatis_MC2_155      NITHILLNNGELGKITQ------EQRSSEYEVWQTSLLNPDFAAYARDCG
                                     :   : ::*  .            :              *..  :.  *

Mflv_4239|M.gilvum_PYR-GCK          CVGLRCEREEDVADVIAQARAINDRPVVVEFVVGADAQVWPMVAAGTSND
Mvan_2122|M.vanbaalenii_PYR-1       CVGLRCERSEDVADVISQARAINDRPVVIEFVVGADAQVWPMVAAGTSND
TH_2440|M.thermoresistible__bu      CVGLRCEREEDVADVIAQARAINDRPVVIDFIVGADAQVWPMVAAGTSND
MMAR_1710|M.marinum_M               CVGLRCEREEDVADVINQAREISDRPVVIDFIVGADAQVWPMVAAGTSND
MUL_1947|M.ulcerans_Agy99           CVGLRCEREEDVADVINQATEISDRPVVIDFIVGADAQVWPMVAAGTSND
MLBr_01696|M.leprae_Br4923          CVGLRCECEEDVVDVINQARAINNRPVVIDFIVGADAQVWPMVAAGASND
MAB_3323c|M.abscessus_ATCC_199      CVGLRCEREEDVAKVIEEARAINDRPVVIDFIVGADAQVWPMVAAGTSND
Rv3470c|M.tuberculosis_H37Rv        AEGIRVDTRCELRAGVQKALAATG-PCVLDIAIDPEINK-PDIGLGR---
Mb3499c|M.bovis_AF2122/97           AEGIRVDTRCELRAGVQKALAATG-PCVLDIAIDPEINK-PDIGLGR---
MAV_4935|M.avium_104                AKGYRISHADELLPTLRAALDDDG-VSLISCPVDYSENLRLTNRLGELDE
MSMEG_5593|M.smegmatis_MC2_155      AYGNQVISHTELGTVIAEALAHPG-PALVEIITDAWSN------------
                                    . * :     ::   :  *    .   ::.   .   :            

Mflv_4239|M.gilvum_PYR-GCK          EIQAARGIRPLFD-NEEGHA-
Mvan_2122|M.vanbaalenii_PYR-1       EIQAARGIRPLFD-NEEGHA-
TH_2440|M.thermoresistible__bu      EIMAARDIRPLFDESDEGHA-
MMAR_1710|M.marinum_M               EIQAARGIRPLFDDESEGHA-
MUL_1947|M.ulcerans_Agy99           EIQAARGIRPLFDDESEGHA-
MLBr_01696|M.leprae_Br4923          EIQAARGIRPLFDDESEGHV-
MAB_3323c|M.abscessus_ATCC_199      EIQAARGIRPLFDDDELVADE
Rv3470c|M.tuberculosis_H37Rv        ---------------------
Mb3499c|M.bovis_AF2122/97           ---------------------
MAV_4935|M.avium_104                TL-------------------
MSMEG_5593|M.smegmatis_MC2_155      ---------------------