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NETPHAPVVEQVLVAAAFGNQPGSWPLPTAITPHHLWLRAVAAGGQGRYAHAYGDLSVLRRLVPAGPLAS LAHSTQGSLLRQLGWHTLARGWDGRALALAGADREAGADALIGLAADALGVGRFAAAGALLDRADPLVVS PLVADRLAVRRRWVAAELAMATGDGATAVRHAEEAVELTQAMAVASARHRVKSDVVLAAALCSAGAVARA RAVGEEALDATARFGLLPLRWALACLLIDIGTVTFSAQQLRELTKIRNICAGQVRRAGGCWRTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3415c | - | - | 100% (275) | hypothetical protein Rv3415c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3449c | - | 1e-155 | 100.00% (275) | hypothetical protein Mb3449c |
| M. gilvum PYR-GCK | Mflv_4913 | - | 1e-70 | 55.85% (265) | hypothetical protein Mflv_4913 |
| M. leprae Br4923 | MLBr_00383 | - | 1e-107 | 73.48% (279) | hypothetical protein MLBr_00383 |
| M. abscessus ATCC 19977 | MAB_3725c | - | 6e-64 | 51.91% (262) | hypothetical protein MAB_3725c |
| M. marinum M | MMAR_1133 | - | 7e-97 | 68.13% (273) | hypothetical protein MMAR_1133 |
| M. avium 104 | MAV_4360 | - | 9e-98 | 70.11% (271) | hypothetical protein MAV_4360 |
| M. smegmatis MC2 155 | MSMEG_1598 | - | 1e-74 | 59.40% (266) | hypothetical protein MSMEG_1598 |
| M. thermoresistible (build 8) | TH_2747 | - | 7e-77 | 58.62% (261) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1507 | - | 2e-69 | 57.68% (267) | hypothetical protein Mvan_1507 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4913|M.gilvum_PYR-GCK ----------------MDTTPAVSANDLSTAAFGGDPGLWPLPPASGAHD
Mvan_1507|M.vanbaalenii_PYR-1 ----------------MSTAAAATANALHDAAFGADPGAWPLPPATEPLQ
Rv3415c|M.tuberculosis_H37Rv --------MN------ETPHAPVVEQVLVAAAFGNQPGSWPLPTAITPHH
Mb3449c|M.bovis_AF2122/97 --------MN------ETPHAPVVEQVLVAAAFGNQPGSWPLPTAITPHH
MLBr_00383|M.leprae_Br4923 --------MTSVSIVVEIGHTSAAEPMLAAAAFGNQPGRWPLPTATTPHQ
MAV_4360|M.avium_104 ---------------MQANVDGSVDRLLAEAAFGDRPDRWPLPAAGTPAQ
MMAR_1133|M.marinum_M MGACVGPGITESDDRNFAVVASAIESTLDDAAFGSRPDRWPLPAAITPRQ
MSMEG_1598|M.smegmatis_MC2_155 -----------------MSAIDDVTATLAEAAFGDDPGRWPLPSASTPHE
TH_2747|M.thermoresistible__bu ------------MASRTCGTSGTAGEVLTSAAFGEDPGRWPLPPAATPHE
MAB_3725c|M.abscessus_ATCC_199 ----------------MVTSPASASITLLDAAFGASPATWPLPCASTPQD
* **** * **** * . .
Mflv_4913|M.gilvum_PYR-GCK LWVRAVVAGGQGRYASGFADLDRLERLPR---SATTSSLALSTRASFLRQ
Mvan_1507|M.vanbaalenii_PYR-1 WWLRAVAAGGQGRYASALADLDRLRRLTV---TDALASLALSTRASFLRQ
Rv3415c|M.tuberculosis_H37Rv LWLRAVAAGGQGRYAHAYGDLSVLRRLVP---AGPLASLAHSTQGSLLRQ
Mb3449c|M.bovis_AF2122/97 LWLRAVAAGGQGRYAHAYGDLSVLRRLVP---AGPLASLAHSTQGSLLRQ
MLBr_00383|M.leprae_Br4923 LWLRAVAAGGQGHYSSAYRDLAVLRRSVP---AGRLASLAHSTHGSFLRQ
MAV_4360|M.avium_104 LWLRAVAAGGQGRYGAALHDLARLRRTAT---AGRLASLAHSTQGSFLRQ
MMAR_1133|M.marinum_M LWLRAVAAGGQGRYGSAYSDLALLRRRVP---ADRWSSLAHSTHASFLRQ
MSMEG_1598|M.smegmatis_MC2_155 RWLRAVAAGGQGRYNCALTELAELIRAERGSLGTPLVSLAHSTRASFLRQ
TH_2747|M.thermoresistible__bu LWLRAVAAGGQGRYGTALADLDTLRRGCA---GGAHHSLAHSTHASFLRQ
MAB_3725c|M.abscessus_ATCC_199 AWLRAIALGGAGRYAAAHAELSAIPASRP----GGLASLALSTRASLLRQ
*:**:. ** *:* . :* : *** **:.*:***
Mflv_4913|M.gilvum_PYR-GCK LGWHTVARGWDGRAAAVAAGSAEPGAADAGADALIGLAADALGVGRFAAS
Mvan_1507|M.vanbaalenii_PYR-1 LGWHDRARTWDGRAAALAA------TGEAGADALIGLAADALGVGRFAAS
Rv3415c|M.tuberculosis_H37Rv LGWHTLARGWDGRALALAGA-----DREAGADALIGLAADALGVGRFAAA
Mb3449c|M.bovis_AF2122/97 LGWHTLARGWDGRALALAGA-----DREAGADALIGLAADALGVGRFAAA
MLBr_00383|M.leprae_Br4923 LGWHSLARGWDGRALVLAGT-----DSEARADALIGLAADALGVGRLAAA
MAV_4360|M.avium_104 LGWHALARGWDGRALALAGD-----DPEAGADALIGLAADALGVGRFAAA
MMAR_1133|M.marinum_M LGWHTRARRWDGRALALAGA-----DPEAATDALVGLAADALGVGRFAAS
MSMEG_1598|M.smegmatis_MC2_155 LGWHTRARGADGLAWAHRGT-----DPEAAADALVGLAADALGVGRFAAS
TH_2747|M.thermoresistible__bu LGGHAHARGWDGRAWAAAGN-----HPDAAADALVGLAADALGLGRFSLA
MAB_3725c|M.abscessus_ATCC_199 LAWHTHARGFDGRALSLAGS-----DAEARSDALVGLAADALGLARFPLA
*. * ** ** * . :* :***:********:.*:. :
Mflv_4913|M.gilvum_PYR-GCK ARALEGAAE-----LIGAAATSRPAVRMGWVSSELAMFRGDGPTAVAHAR
Mvan_1507|M.vanbaalenii_PYR-1 ARALERAAD-----ALADTDCPRLPVRFAWVSAELAMFRGEGGRAVGHAE
Rv3415c|M.tuberculosis_H37Rv GALLDRAD----PLVVSPLVADRLAVRRRWVAAELAMATGDGATAVRHAE
Mb3449c|M.bovis_AF2122/97 GALLDRAD----PLVVSPLVADRLAVRRRWVAAELAMATGDGATAVRHAE
MLBr_00383|M.leprae_Br4923 ATLLRRVGSALAPAQLPAQVADRLAVRRRWVAAELAMAVGDGATAVRHAR
MAV_4360|M.avium_104 AALLARVEP---LLDSENIVPQRISVRRGWVAAELAMARGDGELAVRRAG
MMAR_1133|M.marinum_M AALLSRADTVVAAAQLPPQVADRLAVRRCWVGAELAMFSGDGRTAVGLAE
MSMEG_1598|M.smegmatis_MC2_155 ARLLERAR------TELGDVSARVAVRSAWVSAELAMVTGDGPTAVVHAE
TH_2747|M.thermoresistible__bu RRLLDRSA------VPAAQGSQRLRVRQAWVTAELAMARGDAGTAVTHAE
MAB_3725c|M.abscessus_ATCC_199 HALLEQAEP--LSGRGDARWPWRLPLRLAWVHAELAMVSGDGERALRYAH
* * :* ** :**** *:. *: *
Mflv_4913|M.gilvum_PYR-GCK RAVDLAAGFGS------VRHRVKSHVVLAAALCSSGDLDAARQEGDLALA
Mvan_1507|M.vanbaalenii_PYR-1 RGAHLAESVGS------ARHTVKSQVILAAALCSRGDLDASRRVAGNALD
Rv3415c|M.tuberculosis_H37Rv EAVELTQAMAV----ASARHRVKSDVVLAAALCSAGAVARARAVGEEALD
Mb3449c|M.bovis_AF2122/97 EAVELTQAMAV----ASARHRVKSDVVLAAALCSAGAVARARAVGEEALD
MLBr_00383|M.leprae_Br4923 EAVELAQVGRV----VSVRHQVKSDVVLAAALCSA-ATERARVVAEAALA
MAV_4360|M.avium_104 EAVEAAAATALGAAGAAARHQVKSEVVLAAALCSAGDIERARAVADTALH
MMAR_1133|M.marinum_M RGVELARASGG----ASARHRVKSDVVLAAALCSAGVIDKARVIGEAAFD
MSMEG_1598|M.smegmatis_MC2_155 RGVAAAAEYAS------RRHTIKSDVVMAAALCSAGRPDDARVVADKALQ
TH_2747|M.thermoresistible__bu QAVDLAAALGS------ARHRVKSAVVLAAALCAGGELDRSRRIADAALG
MAB_3725c|M.abscessus_ATCC_199 AAEELAQDVPS------VRHQVKTTMVLAAALSSVGDLDKSAVVAARGLR
. : ** :*: :::****.: : . .:
Mflv_4913|M.gilvum_PYR-GCK DATRSGLVPLQWAVACLLADIGSQAYPAA---RIRAVRDASAEAVTRWGG
Mvan_1507|M.vanbaalenii_PYR-1 AAQRLGLVPLQWAVASLLADIGADDRSPA---QIRGIRDAAAEAVIRWGG
Rv3415c|M.tuberculosis_H37Rv ATARFGLLPLRWALACLLIDIGTVTFSAQQLRELTKIRNICAGQVRRAGG
Mb3449c|M.bovis_AF2122/97 ATARFGLLPLRWALACLLIDIGTVTFSAQQLRELTKIRNICAGQVRRAGG
MLBr_00383|M.leprae_Br4923 ATGRLGLIPLRWALACLLIDIGSVTFSEP---ELSELRDVCADQVRRAGG
MAV_4360|M.avium_104 TTARLRLVPLRWALACLLIDIGSVEFSSR---QLHEIREVCAGQVRRAGG
MMAR_1133|M.marinum_M DAGRLGLIPLRWALACLLIDTESVTLPVN---QLREIRDICADQVWRAGG
MSMEG_1598|M.smegmatis_MC2_155 ATGDNGLIPLRWALACLLADIGSTAHTLE---EVREIRDGTADTVRRRGG
TH_2747|M.thermoresistible__bu DTERYGLVPLRWAVCCLLADIGSAALSPE---RVAAVRAEAADTVRRRGG
MAB_3725c|M.abscessus_ATCC_199 AASAHKLVPLRWALAAMLAGLPTPDEAGRRGEDLVAVRRECAAWIARAGG
: *:**:**:..:* . : . : :* * : * **
Mflv_4913|M.gilvum_PYR-GCK VWRPR-----------
Mvan_1507|M.vanbaalenii_PYR-1 VWRRR-----------
Rv3415c|M.tuberculosis_H37Rv CWRTA-----------
Mb3449c|M.bovis_AF2122/97 CWRTA-----------
MLBr_00383|M.leprae_Br4923 TWRTA-----------
MAV_4360|M.avium_104 TWRSA-----------
MMAR_1133|M.marinum_M TWRPA-----------
MSMEG_1598|M.smegmatis_MC2_155 VWSSR-----------
TH_2747|M.thermoresistible__bu VWTARDPGPTDPTDKV
MAB_3725c|M.abscessus_ATCC_199 EWRLEVVD--------
*