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PGTKPGSDKPTGRVVVVIVLLMLAGAALRGHLPADDGAPLAAAGGSRAALMFIVAALAATLALIALAIIT RLRHPLPVAPSAGELSAMLGGAAGRPNWRVLLLGLGTILAWLLIAILLARLFVPDDVGPAAPIPDSTATP DASSTTPSRPQPPQDNNDDVLGILFASTIGLFLMVVAGSLITSRRQRKSAPARISGDRIESPAPSARSES LARAAEIGLAEMADLRREPREAIIACYVAMERELSHVPGVAPQDFDTPTEVLARAVEHRALHGASAAALV SLFAEARFSPHVMNEEHREVAMRLLRLVLDELSTRTAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3166c | - | - | 100% (319) | hypothetical protein Rv3166c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3191c | - | 1e-176 | 100.00% (319) | hypothetical protein Mb3191c |
| M. gilvum PYR-GCK | Mflv_0478 | - | 1e-51 | 42.50% (320) | hypothetical protein Mflv_0478 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1911c | - | 4e-36 | 34.49% (316) | hypothetical protein MAB_1911c |
| M. marinum M | MMAR_1397 | - | 1e-92 | 57.05% (312) | hypothetical protein MMAR_1397 |
| M. avium 104 | MAV_4054 | - | 1e-100 | 60.88% (317) | hypothetical protein MAV_4054 |
| M. smegmatis MC2 155 | MSMEG_3869 | - | 5e-52 | 39.81% (309) | hypothetical protein MSMEG_3869 |
| M. thermoresistible (build 8) | TH_4643 | - | 1e-48 | 50.00% (230) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2480 | - | 3e-92 | 57.05% (312) | hypothetical protein MUL_2480 |
| M. vanbaalenii PYR-1 | Mvan_0178 | - | 4e-54 | 42.04% (314) | hypothetical protein Mvan_0178 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0478|M.gilvum_PYR-GCK MPEHTGPGDHRAVVRTIAVIVLIAVALVALRGYLPEASEPRPEPERLDSG
Mvan_0178|M.vanbaalenii_PYR-1 MPDKIEPADNRAVVRTVAVAVLLLLAVVALRGYLPDGDRAAPPDERPESG
Rv3166c|M.tuberculosis_H37Rv -MPGTKPGSDKPTGRVVVVIVLLMLAGAALRGHLPADDGA--PLAAAGGS
Mb3191c|M.bovis_AF2122/97 -MPGTKPGSDKPTGRVVVVIVLLMLAGAALRGHLPADDGA--PLAAAGGS
MMAR_1397|M.marinum_M -----MPGIDKPTGRVVALIVLLILVAAALRGYLPDDDGS--SHTEPATS
MUL_2480|M.ulcerans_Agy99 -----MPGIDKPTGRVVALIVLLILVAAALRGYLPDDDGT--SHTEPATS
MAV_4054|M.avium_104 -MP--MPGMDKPTGRVVALIVLLLVVAAALRGYLPAQHDA--TRSEAG-G
TH_4643|M.thermoresistible__bu --------------------------------------------------
MSMEG_3869|M.smegmatis_MC2_155 -----MPGLQNAAGRVATVLVLMVVAVVALRGHVPGGSRA--QAQAPTDS
MAB_1911c|M.abscessus_ATCC_199 -----MTGADRPLLRATGLIVLIALSVVALRSYLPDAAALP-----PPEK
Mflv_0478|M.gilvum_PYR-GCK SGSVAAVVAMLAVSLAAIAISVLAQARQ-RSGIPSAAEPHRAPRAGPLRL
Mvan_0178|M.vanbaalenii_PYR-1 TGSLVAVAAMLAVSIGIIAISILAQGRH-RLPAPDQGGPVRDLREPWPGL
Rv3166c|M.tuberculosis_H37Rv RAALMFIVAALAATLALIALAIITRLRHPLPVAPSAGELSAMLGGAAGRP
Mb3191c|M.bovis_AF2122/97 RAALMFIVAALAATLALIALAIITRLRHPLPVAPSAGELSAMLGGAAGRP
MMAR_1397|M.marinum_M RPALVFVIAVLSGSVALMAFAIIARLRDPRAVAPSAGDLAQMLGGGHRRT
MUL_2480|M.ulcerans_Agy99 RPALVFVIAVLSGSVALMAFAIIARLRDPRAVAPSAGDLAQMLGGGHRRT
MAV_4054|M.avium_104 RAALGLVVAILAVTLALIAVAIVARLKDPRAPAPPAGALSETLGAGRGRP
TH_4643|M.thermoresistible__bu -----------------------VWRRD-----------------GGSRP
MSMEG_3869|M.smegmatis_MC2_155 PATFVAVAALLTVGLAGFAFAIFTAPRKPRVSGAGDDIPQAGLRGPRARL
MAB_1911c|M.abscessus_ATCC_199 PRAQPHSNALQLLLCGVVSILILVSLRRQRPNMPLPQENPPYLRLPALTR
. :
Mflv_0478|M.gilvum_PYR-GCK RWRPLLIAAAILLAWSVVLLLLMRWVSPLPLDEPPAPQGASATDPAEGAE
Mvan_0178|M.vanbaalenii_PYR-1 RWRPLLIAAAALLVWSVLMLLLMRWASPGVVDDAPPP--APGADARAETD
Rv3166c|M.tuberculosis_H37Rv NWRVLLLGLGTILAWLLIAILLARLFVPDDVGPAAPIPDS-TATPDASS-
Mb3191c|M.bovis_AF2122/97 NWRVLLLGLGTILAWLLIAILLARLFVPDDVGPAAPIPDS-TATPDASS-
MMAR_1397|M.marinum_M SWRVLLIGLAVIAAYLLLTLLLSRLFTPDEVAPSAPVSDPGVPAPTGDG-
MUL_2480|M.ulcerans_Agy99 SWRVLLIGLAVIAAYLLLTLLLSRLFTPDEVAPSAPASDPGVPAPTGDG-
MAV_4054|M.avium_104 TWRVLLIGLGVIVAWLLIVMLLARLFASHGLAPAPPPGTGASPPPHPAAP
TH_4643|M.thermoresistible__bu SWRVVLLGLSLVIAYLLTVTLVARLWAPSDPVRTEPDETGAETGPGIGP-
MSMEG_3869|M.smegmatis_MC2_155 RWRWVLLGLAVLMCWLSVAVLISRLTDTSELPP--PQDGSGRESPGAPG-
MAB_1911c|M.abscessus_ATCC_199 REAIIAAATVLVLMGGVWTALYLSGPAGEGPVREPASRSAEPTRPGAEP-
: . : * . .
Mflv_0478|M.gilvum_PYR-GCK PGPAPAPR------QTGAGDSVFGILAVATVVLLGLSVVGTLRG-RRQIP
Mvan_0178|M.vanbaalenii_PYR-1 RGPAPQTP------TGDGGGSVFVLLAGTTILLLALSVAATLLG-RRRAP
Rv3166c|M.tuberculosis_H37Rv --TTPSRP----QPPQDNNDDVLGILFASTIGLFLMVVAGSLITSRRQRK
Mb3191c|M.bovis_AF2122/97 --TTPSRP----QPPQDNNDDVLGILFASTIGLFLMVVAGSLITSRRQRK
MMAR_1397|M.marinum_M -APRPQQP----QQPSDDNINTLEILLAATAPLLLTILAAVAVLWRRRWR
MUL_2480|M.ulcerans_Agy99 -APRPQQP----QQPSDDNINTLEILLAATAPLLLTILAAVAVLWRRRWR
MAV_4054|M.avium_104 PAPPPQHP----QRPRDGSQDTLGILLAGTVAMLLMVVASAVAGARRRWR
TH_4643|M.thermoresistible__bu -EVDPAVPGSSWADPPSAAADAMPHLPAATIAFVLMVIVGSLAARRRGLT
MSMEG_3869|M.smegmatis_MC2_155 ---EARVP----DDPGD--ATAFRLLAVAGVIMLLLIAIGTILRARRR-A
MAB_1911c|M.abscessus_ATCC_199 --PAPGKP----------SPRRYSEVPMMILGVVLVGIAAAVFVLRRHEP
. : .. . **
Mflv_0478|M.gilvum_PYR-GCK APAV---PVEAPSDATTGGAGPDLVRAAELGLAEVDDPNRDAREAIIACY
Mvan_0178|M.vanbaalenii_PYR-1 APPP---PVDPATVGTTP-AEPDLARAAELGLAEMGDLSRDPRQAIIACY
Rv3166c|M.tuberculosis_H37Rv SAPARISGD-RIESPAPSARSESLARAAEIGLAEMADLRREPREAIIACY
Mb3191c|M.bovis_AF2122/97 SAPARISGD-RIESPAPSARSESLARAAEIGLAEMADLRREPREAIIACY
MMAR_1397|M.marinum_M AETSNTHTDVAGESPEPPQRSQLLVRAAKVGLAEMADLERDPREAIIACY
MUL_2480|M.ulcerans_Agy99 AETSNTHTDVAGESPEPPQRSQLLVRAAKVGLAEMADLERDPREAIIACY
MAV_4054|M.avium_104 SPAP-AVPDEPAENPAPQPHSESLARAAERGLAEMADLRRDPREAIIACY
TH_4643|M.thermoresistible__bu ASAP---TAAAAPAAPAERRSGSLARAAEVGLAEIGEPGREPRDAIIACY
MSMEG_3869|M.smegmatis_MC2_155 AAHLHRADDTWPVLPVHPRNPEKLVRATELGLAEIGDLSRDPRTAIIACY
MAB_1911c|M.abscessus_ATCC_199 DAPD-GSTGQPAEPDATPTTPRSLVHLVELGLAEVAEPGRDPRAAIIACY
*.: .: ****: : *:.* ******
Mflv_0478|M.gilvum_PYR-GCK LAMERELEKSPGTTPQDSDTPSEVLARATRHHALQADSAAELVDLFEETR
Mvan_0178|M.vanbaalenii_PYR-1 LAMERELEKSPGTIPQESDTPSEVLARAIERHALRADTGIELVDLFEEAR
Rv3166c|M.tuberculosis_H37Rv VAMERELSHVPGVAPQDFDTPTEVLARAVEHRALHGASAAALVSLFAEAR
Mb3191c|M.bovis_AF2122/97 VAMERELSHVPGVAPQDFDTPTEVLARAVEHRALHGASAAALVSLFAEAR
MMAR_1397|M.marinum_M AAMERELANVPAAAPRDFDTPTEVLARAVQHHALQADNAVQLVNLFAEAR
MUL_2480|M.ulcerans_Agy99 AAMERELANVPAAAPRDFDTPTEVLARAVQHHALQADNAVQLVNLFAEAR
MAV_4054|M.avium_104 AAMERELAHVPGAVPQDFDTPSEVLARAVEHHALHADNAVQLVNLFTEAR
TH_4643|M.thermoresistible__bu AAMERELARVPDAAPQQFDTASEVLARAVEHHALPPGSATRLVELFGEAR
MSMEG_3869|M.smegmatis_MC2_155 AAMEQGLAYAPEAVPQESDTPSEVLARAVEHHALNADSATELVELFAEAR
MAB_1911c|M.abscessus_ATCC_199 AAMEQGLTAAPEAAPLESDTPSEVLQRAVHIGALQSQAGTQLVSLFSEAR
***: * * . * : **.:*** ** . ** . **.** *:*
Mflv_0478|M.gilvum_PYR-GCK FSPHVMDDGHRVAAVRALQAVLRDLRVAP----------
Mvan_0178|M.vanbaalenii_PYR-1 FSPHVMNEGHRADAVRALRQVQHQLQAAI----------
Rv3166c|M.tuberculosis_H37Rv FSPHVMNEEHREVAMRLLRLVLDELSTRTAI--------
Mb3191c|M.bovis_AF2122/97 FSPHVMNEEHREVAMRLLRLVLDELSTRTAI--------
MMAR_1397|M.marinum_M FSTHVMNEGHRELAVRVLRLVLDELAAPVGASTGRGDEM
MUL_2480|M.ulcerans_Agy99 FSTHVMNEGHRELAVRVLRLVLDELAAPVGALTGRGDEM
MAV_4054|M.avium_104 FSPHVMNEGHRDVAVRVLRLVLDELGSRSVA--------
TH_4643|M.thermoresistible__bu FSRHLMREEHRDAAVDALRVVLGHLRGQT----------
MSMEG_3869|M.smegmatis_MC2_155 FSPHRMTETHRAAAVAALQRVHADLRSLV----------
MAB_1911c|M.abscessus_ATCC_199 FSPHEMTQAHRQSAARWLQDVVDDLRSRQ----------
** * * : ** * *: * .*