For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv3145 (nuoA)

annotation: NADH dehydrogenase subunit A
coordinates: 3511682 - 3512068
length: 128

LNVYIPILVLAALAAAFAVVSVVIASLVGPSRFNRSKQAAYECGIEPASTGARTSIGPGAASGQRFPIKY
YLTAMLFIVFDIEIVFLYPWAVSYDSLGTFALVEMAIFMLTVFVAYAYVWRRGGLTWD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3145nuoA-100% (128)NADH dehydrogenase subunit A

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3169nuoA1e-69100.00% (128) NADH dehydrogenase subunit A
M. gilvum PYR-GCKMflv_4481-3e-4770.31% (128) NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2134-7e-4360.94% (128) NADH dehydrogenase subunit A
M. marinum MMMAR_1483nuoA7e-5885.94% (128) NADH dehydrogenase I (chain a) NuoA (NADH- ubiquinone
M. avium 104MAV_4033nuoA2e-5782.03% (128) NADH dehydrogenase subunit A
M. smegmatis MC2 155MSMEG_2063nuoA4e-4669.05% (126) NADH dehydrogenase subunit A
M. thermoresistible (build 8)TH_0637nuoA2e-4466.41% (128) PROBABLE NADH DEHYDROGENASE I (CHAIN A) NUOA
M. ulcerans Agy99MUL_2459nuoA5e-5885.94% (128) NADH dehydrogenase subunit A
M. vanbaalenii PYR-1Mvan_1885-1e-4668.99% (129) NADH-ubiquinone/plastoquinone oxidoreductase, chain 3

CLUSTAL 2.0.9 multiple sequence alignment


Rv3145|M.tuberculosis_H37Rv         -----------------------------------MNVYIPILVLAALAA
Mb3169|M.bovis_AF2122/97            -----------------------------------MNVYIPILVLAALAA
MMAR_1483|M.marinum_M               MLKVTVTVHTPGPSQQPSQPPGRRAGGPYDGSWSDLNAYIPILVLATLAA
MUL_2459|M.ulcerans_Agy99           -----------------------------------MNAYIPILVLATLAA
MAV_4033|M.avium_104                -----MTVPKPGSSQQPGYRLAAAGG-SHDGSWSELNVYIPILVLGAIAT
Mflv_4481|M.gilvum_PYR-GCK          -----------------------------------MNLYTPILVLGAIAA
Mvan_1885|M.vanbaalenii_PYR-1       ---------------------MVAHIDGPEELLRSMNLYTPILVLGAIAA
MSMEG_2063|M.smegmatis_MC2_155      -----------------------------------MALYTPILILGAIAA
TH_0637|M.thermoresistible__bu      -----------------------------------MDVYTPILVLGAIAA
MAB_2134|M.abscessus_ATCC_1997      -----------------------------------MDAYVPILVLGAIAV
                                                                       :  * ***:*.::*.

Rv3145|M.tuberculosis_H37Rv         AFAVVSVVIASLVGPSRFNRSKQAAYECGIEPASTGARTSIGPGAASGQR
Mb3169|M.bovis_AF2122/97            AFAVVSVVIASLVGPSRFNRSKQAAYECGIEPASTGARTSIGPGAASGQR
MMAR_1483|M.marinum_M               GFAVVSVVIASLVGPTRFNRSKLAAYECGIEPTEAQAGAS-GRETASGQR
MUL_2459|M.ulcerans_Agy99           GFAVVSVVIASLVGPTRFNRSKLAAYECGIEPTEAQAGAS-GRETASGQR
MAV_4033|M.avium_104                AFAVGSVVIASLAGPSRFNKSKMAAYECGIEPTET--SVS-GPRATAGQR
Mflv_4481|M.gilvum_PYR-GCK          VFAVGSVGIALLIGPRRFNRAKLEAYECGIEPMDAS----DPAVAATAQR
Mvan_1885|M.vanbaalenii_PYR-1       VFAVGSVGIALLIGPRRYNRAKLEAYECGIEPMAAT----DPAAAAVGQR
MSMEG_2063|M.smegmatis_MC2_155      VFAVVSVGIALVIGPRRFNRSKLEAYECGIDPLPP------VAAGLTGQR
TH_0637|M.thermoresistible__bu      VFAVVSVGIAVAIGPRRYNRAKLEAYECGIEPTPPS-----AAVGGSAQR
MAB_2134|M.abscessus_ATCC_1997      VFAVFSVGVSSFVGPRRYNRAKLEAYECGIEATQHSMGRDHHGAAAGGHR
                                     *** ** ::   ** *:*::*  ******:.               .:*

Rv3145|M.tuberculosis_H37Rv         FPIKYYLTAMLFIVFDIEIVFLYPWAVSYDSLGTFALVEMAIFMLTVFVA
Mb3169|M.bovis_AF2122/97            FPIKYYLTAMLFIVFDIEIVFLYPWAVSYDSLGTFALVEMAIFMLTVFVA
MMAR_1483|M.marinum_M               FPVKYYLTAMLFIVFDIEIVFLYPWAVSFDALGTFALVEMAIFMLTVFVA
MUL_2459|M.ulcerans_Agy99           FPVKYYLTAMLFIVFDIEIVFLYPWAVSFDALGTFALVEMAIFMLTVFVA
MAV_4033|M.avium_104                FPVKYYLTAMLFIVFDIEIVFLYPWAVSYDALGTFALIEMVVFMLTVFVA
Mflv_4481|M.gilvum_PYR-GCK          FPMRYYLTAMLFIVFDIEIVFLYPWAVAFDSLGMFALIEMLLFMVVVFVA
Mvan_1885|M.vanbaalenii_PYR-1       FPIRYYVTAMLFIVFDIEIVFLYPWAVAFDNLGLFALVEMLLFMVIVFVA
MSMEG_2063|M.smegmatis_MC2_155      IPIRYYLIAMLFIVFDIEIVFLYPWAVAFDSLGLFAVIEMLLFMLTVFVA
TH_0637|M.thermoresistible__bu      FPIKFYLTAMMFIIFDIVIVFLYPWAVAFDGLGVFALVAMLLFMLTVFAA
MAB_2134|M.abscessus_ATCC_1997      VPVKYYLTAMLFIIFDIEIVFLYPWAVHFDALGVFGLLAMALFIVNVSVA
                                    .*:::*: **:**:*** ********* :* ** *.:: * :*:: * .*

Rv3145|M.tuberculosis_H37Rv         YAYVWRRGGLTWD
Mb3169|M.bovis_AF2122/97            YAYVWRRGGLTWD
MMAR_1483|M.marinum_M               YAYVWRRGGLTWD
MUL_2459|M.ulcerans_Agy99           YAYVWRRGGLTWD
MAV_4033|M.avium_104                YAYVWRRGGLTWD
Mflv_4481|M.gilvum_PYR-GCK          YAYVWRRGGLQWD
Mvan_1885|M.vanbaalenii_PYR-1       YGYVWRRGGLQWD
MSMEG_2063|M.smegmatis_MC2_155      YAYVWRRGGLNWD
TH_0637|M.thermoresistible__bu      YVYVRRRGGLTWD
MAB_2134|M.abscessus_ATCC_1997      YAYEWRRGGLSWD
                                    * *  ***** **