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LAAGPALSARGYLALNGQTPAGCSLMEWQNDNNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIISF PPTQWTRWRQPVIGMPSTPRFLGHGRLLVSTHLGQLLVFDTRRGMVVGSPVDLVDGIDPTDATRGLADCA PARPGCPVAAAPAFSSVNGTVVVSVWQPGEPAAKLVGLKYHAEQLVREWTSDAVSAGVLASPVLSADGST VYVNGRDHRLWALNAADGKAKWSAPLGFLAQTPPALTPHGLIVSGGGPDTALAAFRDAGDHAEGAWRRDD VTALSTASLAGTGVGYTVISGPNHDGTPGLSLLVFDPANGHTVNSYPLPGATGYPVGVSVGNDRRVVTAT SDGQVYSFAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3035 | - | - | 100% (360) | hypothetical protein Rv3035 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3061 | - | 0.0 | 100.00% (360) | hypothetical protein Mb3061 |
| M. gilvum PYR-GCK | Mflv_4265 | - | 1e-132 | 61.98% (363) | Pyrrolo-quinoline quinone |
| M. leprae Br4923 | MLBr_01720 | - | 1e-169 | 76.03% (363) | hypothetical protein MLBr_01720 |
| M. abscessus ATCC 19977 | MAB_3379 | - | 1e-115 | 50.41% (363) | hypothetical protein MAB_3379 |
| M. marinum M | MMAR_1667 | - | 0.0 | 82.50% (360) | hypothetical protein MMAR_1667 |
| M. avium 104 | MAV_3899 | - | 1e-175 | 80.17% (363) | hypothetical protein MAV_3899 |
| M. smegmatis MC2 155 | MSMEG_2333 | - | 1e-136 | 64.46% (363) | hypothetical protein MSMEG_2333 |
| M. thermoresistible (build 8) | TH_2189 | - | 1e-58 | 70.63% (143) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1903 | - | 1e-177 | 81.64% (354) | hypothetical protein MUL_1903 |
| M. vanbaalenii PYR-1 | Mvan_2094 | - | 1e-134 | 63.64% (363) | Pyrrolo-quinoline quinone |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4265|M.gilvum_PYR-GCK ---------MLRRIIVVAWTTLVAGVLAGCGTTDSWVASRAASGWSAQYA
Mvan_2094|M.vanbaalenii_PYR-1 ---------MLRRIIVWASTALIAGGLVGCGNTDSWVEARPASGWAAQYA
MSMEG_2333|M.smegmatis_MC2_155 ---------MFRRYLALMVAALLTGLLAGCENTDSWVQASPASGWAAQYA
Rv3035|M.tuberculosis_H37Rv --------------------------------------------------
Mb3061|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1667|M.marinum_M MGTLRNHPVFARRLLTTALAAALTIGLGGCGNTDSWVDAAPALGWPAQYG
MUL_1903|M.ulcerans_Agy99 --------------------------------------------------
MAV_3899|M.avium_104 ----------------MLLAAVVTTGAGACGNTDSWVQASAAQGWPAQYA
MLBr_01720|M.leprae_Br4923 --------------------------------------------------
MAB_3379|M.abscessus_ATCC_1997 --------MLSRARVLASIALAALLTITGCSGDDSWINIKAAPGWSASYA
TH_2189|M.thermoresistible__bu ---------VIRRLMATALTALTTAVLAGCGDAGSWVEAKPAEGWSAQYG
Mflv_4265|M.gilvum_PYR-GCK DAANSSSTPTRGADTLQLEWGRSVKGSLAAQAALGSGNYLAVNAQTEGGC
Mvan_2094|M.vanbaalenii_PYR-1 DAANTSSSPVEGADALRLEWTRSVKGNLAAQVALGSGNYLAVNGQTGAGC
MSMEG_2333|M.smegmatis_MC2_155 DAANSSYKSAPGAQSLRAEWSRSAKGEVGAQVALGSAGYLAVNAQSAGGC
Rv3035|M.tuberculosis_H37Rv ---------------------------MAAGPALSARGYLALNGQTPAGC
Mb3061|M.bovis_AF2122/97 ---------------------------MAAGPALSARGYLALNGQTPAGC
MMAR_1667|M.marinum_M DAANSSYTTTAGSSKLALKWTRSVKGSLAAGPALSGRGYLALNSQTPAGC
MUL_1903|M.ulcerans_Agy99 ---------------------------------MSGRGYLALNSQTPAGC
MAV_3899|M.avium_104 DAANSGYTSTGGASKLALQWTRSVKGSLAAGPALSARGYLGLNAQTPAGC
MLBr_01720|M.leprae_Br4923 ---------------------------MAAGPALSARGYLAMNAQTQAGC
MAB_3379|M.abscessus_ATCC_1997 DAHNSSYTATEGARELTLEWSRNTKGQIRSAAAIGIDNFIAVSADTPSGC
TH_2189|M.thermoresistible__bu DAANSSYTSAAGAEALTLEWSRSVKGELAAQVAVGASGYLAVNAQTPAGC
:. .::.:..:: .**
Mflv_4265|M.gilvum_PYR-GCK SLMVWEVDNRARQRWCTRLVQGGGIASPLFDGFDNLYIGQPGLLQSFPTT
Mvan_2094|M.vanbaalenii_PYR-1 SLMVWETDNRARQRWCTRLVQGGGLSSPLFDDFDNLYIGQPGAVLSFPPT
MSMEG_2333|M.smegmatis_MC2_155 SLMVWEADNNGRQRWCTRLVQGGGWSGPLFDGFDNVYVGQPGAMLSFPPT
Rv3035|M.tuberculosis_H37Rv SLMEWQNDNNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIISFPPT
Mb3061|M.bovis_AF2122/97 SLMEWQNDNNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIISFPPT
MMAR_1667|M.marinum_M SLMEWENNDNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIVAFPVT
MUL_1903|M.ulcerans_Agy99 SLMEWENNDNGRQRWCVRLVQGGGFAGPLFDGFDNLYVGQPGAIVAFPVT
MAV_3899|M.avium_104 SLMEWENTDNGRQRWCVRLVQGGGFAGPLLDGFDNLYVGQPGAFLSFPVT
MLBr_01720|M.leprae_Br4923 SLMEWENNDNGRQRWCVRLVQGGGFGGPLFDGFENLYVGEPGTIFSFPMT
MAB_3379|M.abscessus_ATCC_1997 TLMEWEDNRAARQRWCTRMITGSPWSGPLADGYNNLYVGQPGAVVSFPPT
TH_2189|M.thermoresistible__bu SLMVWEYANSARQRWCTRLVQGGGRTSPLLDGFDNVYIGQPGAILSFPPT
:** *: .*****.*:: *. .** *.::*:*:*:** . :** *
Mflv_4265|M.gilvum_PYR-GCK QWVRWRKPVIGLPLTARLVAPGRVLAVTHLGQVLVFDAHRGTVTGNSLDL
Mvan_2094|M.vanbaalenii_PYR-1 QWIRWRRPVIGMPMTARILTPGNLLVVTHLGQVLVFDAHRGTVTGTSLDL
MSMEG_2333|M.smegmatis_MC2_155 QWIRWRKPVIGMPTTPRLLADGQLLVVTHLGQVLVFDSHRGTVEGTPLDL
Rv3035|M.tuberculosis_H37Rv QWTRWRQPVIGMPSTPRFLGHGRLLVSTHLGQLLVFDTRRGMVVGSPVDL
Mb3061|M.bovis_AF2122/97 QWTRWRQPVIGMPSTPRFLGHGRLLVSTHLGQLLVFDTRRGMVVGSPVDL
MMAR_1667|M.marinum_M QWTRWRQPVIGMPSTPRFLGNGHLLVATHLGQMLVFDAHRGKIVGSPMDL
MUL_1903|M.ulcerans_Agy99 QWTRWRQPVIGMPSTPRFLGNGHLLVATHLGQMLVFDAHRGKIVGSPMDL
MAV_3899|M.avium_104 QWTRWRQPVIGMPTTPRFLGHGQLLVVTHLGQVLVFDSHRGQVAGSPLDL
MLBr_01720|M.leprae_Br4923 QWTRWRQPVIGMPSTPRFLGNGQLLVTTHLGQVLVFDAHRGMVVGSPLDL
MAB_3379|M.abscessus_ATCC_1997 QWIRWRKPVIGAPTTPKIVEPGRLLIVTHLGQILIFDAQRGEVVGTPMDL
TH_2189|M.thermoresistible__bu QWIRWRKPVIGMPTTPRILAPGELLVVTHLGQVLLFDAHRGTVTGTPLDL
** ***:**** * *.::: *.:* *****:*:**::** : *..:**
Mflv_4265|M.gilvum_PYR-GCK VAGLDPRDSERGLADCRQARP---------------------ECPIAAAP
Mvan_2094|M.vanbaalenii_PYR-1 VDGVDPTDSERGLDDCRLAGP---------------------RCPVASAP
MSMEG_2333|M.smegmatis_MC2_155 VSGVDPTDSERGLADCPLARS---------------------RCPVAAAP
Rv3035|M.tuberculosis_H37Rv VDGIDPTDATRGLADCAPARP---------------------GCPVAAAP
Mb3061|M.bovis_AF2122/97 VDGIDPTDATRGLADCAPARP---------------------GCPVAAAP
MMAR_1667|M.marinum_M VEGVDPTDPARGLADCAPARQ---------------------GCPVAAAP
MUL_1903|M.ulcerans_Agy99 VEGVDPTDPARGLADCAPARQ---------------------GCPVAAAP
MAV_3899|M.avium_104 VDGVDPTDATRGLADCAPARP---------------------DCPVPAAP
MLBr_01720|M.leprae_Br4923 VDGVNPTDPTRGLADCVSAQR---------------------GCPVASAP
MAB_3379|M.abscessus_ATCC_1997 LEGVDPADPRRGLEDCEPARP---------------------KCPISASP
TH_2189|M.thermoresistible__bu VAGVDPTDSERGLADCAGARXXXCWPPPRPPSTVTPRARDAARHPTARLP
: *::* *. *** ** * * . *
Mflv_4265|M.gilvum_PYR-GCK AYSDSNGMVVLTLWEPGADKP----------------VLVGLRYQQGQTP
Mvan_2094|M.vanbaalenii_PYR-1 AYSAATGMVVLTLWEPNADKP----------------VLVGLRYRPGQTP
MSMEG_2333|M.smegmatis_MC2_155 AFSGQTNIVVLSLWQPGAEAP----------------VLVGLNYRPGQKP
Rv3035|M.tuberculosis_H37Rv AFSSVNGTVVVSVWQPGEPAA----------------KLVGLKYHAEQ--
Mb3061|M.bovis_AF2122/97 AFSSVNGTVVVSVWQPGEPAA----------------KLVGLKYHAEQ--
MMAR_1667|M.marinum_M AFSKVNGMVVVGVWQPGAPAA----------------GLVGLKYHAQQ--
MUL_1903|M.ulcerans_Agy99 AFSKVNGMVVVGIWQPGAPAA----------------GLVGLKYHAQQ--
MAV_3899|M.avium_104 AFSAATGMVVLGVWQPGAPSA----------------GLVGLKYHPGQSP
MLBr_01720|M.leprae_Br4923 AYSPASQTVVLDIWQPGAPTA----------------GLIGLKYHSRQTP
MAB_3379|M.abscessus_ATCC_1997 AYDPATGTIVTTLWQPDKPVP----------------VLLGITYDADGKV
TH_2189|M.thermoresistible__bu AMTETTEPGIGSEGAGDLPAPNPHATAEQVEAAMRDSKLAQILYHDWEAE
* . : . . * : *
Mflv_4265|M.gilvum_PYR-GCK QLTREWTS------------------------------------------
Mvan_2094|M.vanbaalenii_PYR-1 QLTREWTS------------------------------------------
MSMEG_2333|M.smegmatis_MC2_155 LLTQAWTS------------------------------------------
Rv3035|M.tuberculosis_H37Rv -LVREWTS------------------------------------------
Mb3061|M.bovis_AF2122/97 -LVREWTS------------------------------------------
MMAR_1667|M.marinum_M -LVREWTS------------------------------------------
MUL_1903|M.ulcerans_Agy99 -LVREWTS------------------------------------------
MAV_3899|M.avium_104 LLTREWTS------------------------------------------
MLBr_01720|M.leprae_Br4923 LLARAWTS------------------------------------------
MAB_3379|M.abscessus_ATCC_1997 TLKHKWAS------------------------------------------
TH_2189|M.thermoresistible__bu SYDDKWSISYDQRCVDYARGRFDAIVPDHVQRELPYDNALELGCGTGFFL
*:
Mflv_4265|M.gilvum_PYR-GCK -DAVGGGPLAS-PVLSHDGATVYVNGRDERLWAINTA------------D
Mvan_2094|M.vanbaalenii_PYR-1 -DAVGGGPLAS-PVLSADGSTVYVNGRDESLWAINVD------------D
MSMEG_2333|M.smegmatis_MC2_155 -DAAGRGPLAS-PVLSADGQTVYVSGRDEQLWALNSA------------D
Rv3035|M.tuberculosis_H37Rv -DAVSAGVLAS-PVLSADGSTVYVNGRDHRLWALNAA------------D
Mb3061|M.bovis_AF2122/97 -DAVSAGVLAS-PVLSADGSTVYVNGRDHRLWALNAA------------D
MMAR_1667|M.marinum_M -DAVKDGVLAS-PVLSADGETVYVNGRDQRLWALHAT------------D
MUL_1903|M.ulcerans_Agy99 -DAVKDGVLAS-PVLSADGETVYVNGRDQRLWALHAT------------D
MAV_3899|M.avium_104 -DAVGAGVIAS-PVLSADGSTVYVNGRDQRLWALRAA------------D
MLBr_01720|M.leprae_Br4923 -DAIGAGVLAS-PVLSADGSTVYVNGRDQHLWALHAA------------N
MAB_3379|M.abscessus_ATCC_1997 -KIIDEGVIGS-PVMSNDGETVYINDRKGSLHAMHTF------------D
TH_2189|M.thermoresistible__bu LNLIQSGVARRGSVTDLSPGMVRVATRNGRSLGLDVDGRVADAEGIPYDD
. * .* . . * : *. .: :
Mflv_4265|M.gilvum_PYR-GCK GSEKWSVPLGYLAQTP----------PSVTPDGLVIAGGGPGSR------
Mvan_2094|M.vanbaalenii_PYR-1 GSEKWSVPLQYLAQTP----------PSVTPGGLVIAGGGPGSR------
MSMEG_2333|M.smegmatis_MC2_155 GTVKWSVPLDYLAQTP----------PSVAPDGLIVAGGGPDAK------
Rv3035|M.tuberculosis_H37Rv GKAKWSAPLGFLAQTP----------PALTPHGLIVSGGGPDTA------
Mb3061|M.bovis_AF2122/97 GKAKWSAPLGFLAQTP----------PALTPHGLIVSGGGPDTA------
MMAR_1667|M.marinum_M GKVKWSVPLGFLAQTP----------PTVTPEGLIVSGGGPDTR------
MUL_1903|M.ulcerans_Agy99 GKVKWSVPLGFLAQTP----------PTVTPEGLIVSGGGPDTR------
MAV_3899|M.avium_104 AKVKWSAPLGFLAQTP----------PAVTPQGLIVAGGGPDTR------
MLBr_01720|M.leprae_Br4923 GKPKWSVPLEFLAQTP----------PTVTPQGLIVSGGGPDTR------
MAB_3379|M.abscessus_ATCC_1997 GSQKWSLPLGFNATTP----------PSVAPDGTIIAGTGDKAT------
TH_2189|M.thermoresistible__bu NTFDLVVGHAVLHHIPDVELSLREVVRVLRPGGRFVFAGEPTTVGNSYAR
. . * : * * .: . :
Mflv_4265|M.gilvum_PYR-GCK -------LVAIRDTADDGEELWTRE----------------------EVA
Mvan_2094|M.vanbaalenii_PYR-1 -------LTAVRDTASEGEVLWTRD----------------------DTS
MSMEG_2333|M.smegmatis_MC2_155 -------LTAVRDEGDRGEIVWTRD----------------------DVA
Rv3035|M.tuberculosis_H37Rv -------LAAFRDAGDHAEGAWRRD----------------------DVT
Mb3061|M.bovis_AF2122/97 -------LAAFRDAGDHAEGAWRRD----------------------DVT
MMAR_1667|M.marinum_M -------LAAFRDAGDHADQAWRRD----------------------DVT
MUL_1903|M.ulcerans_Agy99 -------LAAFRDAGDHAYQAWRRD----------------------DVA
MAV_3899|M.avium_104 -------LAAFRDAGDHADQVWRRD----------------------DLI
MLBr_01720|M.leprae_Br4923 -------LAAFKDAGDHAQQIWRRD----------------------DLT
MAB_3379|M.abscessus_ATCC_1997 -------LVGIKDSGAKGEIAWRRD----------------------DLV
TH_2189|M.thermoresistible__bu ALSTLTWHVATTVTRLPGLQGWRRPQAELDESSRAAALEAVVDLHTFEPS
.. . * * :
Mflv_4265|M.gilvum_PYR-GCK PLTTSSLAG--LGYAVVRDGD-GESAGLALRVFTLGDG-TTVNTYPLPNA
Mvan_2094|M.vanbaalenii_PYR-1 PLTTSSLAG--VGYAVVPDDS-GDGAGFALTVFNLGDG-GTVNTYPLPRA
MSMEG_2333|M.smegmatis_MC2_155 PLTTSSRSGN-VGYAVARQG----GHGQALLVFDTGDG-RTLQTHPLPEA
Rv3035|M.tuberculosis_H37Rv ALSTASLAGTGVGYTVISGPNHDGTPGLSLLVFDPANG-HTVNSYPLPGA
Mb3061|M.bovis_AF2122/97 ALSTASLAGTGVGYTVISGPNHDGTPGLSLLVFDPANG-HTVNSYPLPGA
MMAR_1667|M.marinum_M PLSTSSLAAGNVGYTIVAGPPHEGGPGMSLLVFNPADG-HTINSYSLPAA
MUL_1903|M.ulcerans_Agy99 PLSTSSLAAGNVGYTIVAGPPHEGGPGMSLLVFNPADG-HTINSYSLPAA
MAV_3899|M.avium_104 PLSSSSLAG--VGYTVVSGPPANGAPGMSVLVFDPGDG-HTLNSYPLPAA
MLBr_01720|M.leprae_Br4923 PLSTSSLAGVSVGYTVVSSSPAADAPGMSLLAFDPRNG-HTLNSYPLPAA
MAB_3379|M.abscessus_ATCC_1997 PLSTSSQAAGNVGYAVVR----DGDKGLALVVFNTPDG-ATINRYPLPDA
TH_2189|M.thermoresistible__bu DLERMARNAGAVEVATASEEFTAAMLGWPVRTFEAAVPPGKLGWNWAKFA
* : . : : * .: .* .: *
Mflv_4265|M.gilvum_PYR-GCK SGWPVGVSIGHDGRVVTATSDGQVY-----GFAPA-
Mvan_2094|M.vanbaalenii_PYR-1 TGWPVGVSVGHDGRVVTATSDGQVY-----GFAPA-
MSMEG_2333|M.smegmatis_MC2_155 TGWPVGVSIGHDGRVVTATSDGQVY-----GFSPA-
Rv3035|M.tuberculosis_H37Rv TGYPVGVSVGNDRRVVTATSDGQVY-----SFAP--
Mb3061|M.bovis_AF2122/97 TGYPVGVSVGNDRRVVTATSDGQVY-----SFAP--
MMAR_1667|M.marinum_M TGYPVGVSIAVDGRVVTATSDGQVY-----SFAPA-
MUL_1903|M.ulcerans_Agy99 TGYPVGVSIAVDGRVVTATSDGQVY-----SFAPA-
MAV_3899|M.avium_104 TGYPLGVSVGTDRRVVAAISDGQVY-----GFAPA-
MLBr_01720|M.leprae_Br4923 TGYPVGVSIANNRRVITVTSDGQLY-----SFAPT-
MAB_3379|M.abscessus_ATCC_1997 TGFPVGISIGPDQRVIVTLSEGLVY-----GFRPET
TH_2189|M.thermoresistible__bu FGSWTALSWVDANVWRRVMPKGWFYNVMVTGVKPS-
* .:* . ..* .* .. *