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M. tuberculosis H37Rv Rv3017c (esxQ)

annotation: ESAT-6 LIKE PROTEIN ESXQ (TB12.9) (ESAT-6 LIKE PROTEIN 8)
coordinates: 3376490 - 3376852
length: 120

SQSMYSYPAMTANVGDMAGYTGTTQSLGADIASERTAPSRACQGDLGMSHQDWQAQWNQAMEALARAYRR
CRRALRQIGVLERPVGDSSDCGTIRVGSFRGRWLDPRHAGPATAADAGD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3017cesxQ-100% (120)ESAT-6 LIKE PROTEIN ESXQ (TB12.9) (ESAT-6 LIKE PROTEIN 8)
M. tuberculosis H37RvRv3019cesxR1e-2265.71% (70) secreted ESAT-6 like protein ESXR (TB10.3) (ESAT-6 like
M. tuberculosis H37RvRv0288esxH1e-2165.22% (69) low molecular weight protein antigen 7 ESXH (10 kDa

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3042cesxQ3e-68100.00% (120) putative ESAT-6 like protein 8
M. gilvum PYR-GCKMflv_0323-5e-1955.71% (70) hypothetical protein Mflv_0323
M. leprae Br4923MLBr_02531-2e-1547.83% (69) putative cell surface protein
M. abscessus ATCC 19977MAB_2228c-1e-1550.00% (70) ESAT-6-like protein esxH
M. marinum MMMAR_0547esxH3e-2264.29% (70) EsaT-6 like protein EsxH
M. avium 104MAV_4865-6e-2262.86% (70) low molecular weight protein antigen 7 Cfp7
M. smegmatis MC2 155MSMEG_0621-3e-1958.57% (70) low molecular weight protein antigen 7
M. thermoresistible (build 8)TH_2110-3e-1855.71% (70) SECRETED ESAT-6 LIKE PROTEIN ESXR (TB10.3) (ESAT-6 LIKE
M. ulcerans Agy99MUL_1210esxH2e-2264.29% (70) EsaT-6 like protein EsxH
M. vanbaalenii PYR-1Mvan_0418-1e-1958.57% (70) hypothetical protein Mvan_0418

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_0621|M.smegmatis_MC2_155      -MSQIMYNYPAMLAHAAEMNTYSGALHAVGADIAAEQHALASAWQGDTGM
TH_2110|M.thermoresistible__bu      -MSQIMYNYPAMLAHVAEMNSYAGALHAVGADIASEQAALAGAWQGDTGT
Mflv_0323|M.gilvum_PYR-GCK          -MSQIMFNYPAMLNHAGEMSSYAGALQAIGADIAAEQAALKSAWQGDTGV
Mvan_0418|M.vanbaalenii_PYR-1       -MSQIMYNYPAMLAHAGEMNSYAGALHAVGADIAAEQTALQSAWQGDTGL
MAB_2228c|M.abscessus_ATCC_199      -MSQITFNYPAMLAHAGEMNTYSGVLTALGADLAAQQASLQAAWHGDTSM
MLBr_02531|M.leprae_Br4923          -MTQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGI
MMAR_0547|M.marinum_M               -MSQIMYNYPAMLAHAGDMSGYAGTMQGLGADISAEQAALSSAWQGDTGV
MUL_1210|M.ulcerans_Agy99           -MSQIMYNYPAMLAHAGDMSGYAGTMQGLGADISAEQAALSSAWQGDTGV
MAV_4865|M.avium_104                MMSQIMYNYPAMLSHAADMSGYAGTMQGLGADIASEQATLSNAWQGDTGM
Rv3017c|M.tuberculosis_H37Rv        -MSQSMYSYPAMTANVGDMAGYTGTTQSLGADIASERTAPSRACQGDLGM
Mb3042c|M.bovis_AF2122/97           -MSQSMYSYPAMTANVGDMAGYTGTTQSLGADIASERTAPSRACQGDLGM
                                     *:*  :.****  :..:*   :*.  .:* *::::: :   .  ** . 

MSMEG_0621|M.smegmatis_MC2_155      TYQAWQAQWNQAMEELVRAYR--------------AMATTHEQNTMAMSA
TH_2110|M.thermoresistible__bu      TYQAWQTQWNTALEELVRAYR--------------AMASTHEMNTMSMNA
Mflv_0323|M.gilvum_PYR-GCK          TYQAWQAQWNTAMEELVRAYR--------------AMASTHEMNTTSMAA
Mvan_0418|M.vanbaalenii_PYR-1       TYQAWQAQWNGAMEELVRAYR--------------AMAATHEMNTTSMAA
MAB_2228c|M.abscessus_ATCC_199      SQAAWQAQWNTAMEELIRAYR--------------AMGSTHETNTLSMNA
MLBr_02531|M.leprae_Br4923          SYQAWQVQWNQATEEMVRAYH--------------AMANTHQNNTLAMLT
MMAR_0547|M.marinum_M               TYQAWQAQWNQAMEDLVRAYQ--------------SMSGTHEANTMAMLA
MUL_1210|M.ulcerans_Agy99           TYQAWQAQWNQAMEDLVRAYQ--------------SMSGTHEANTMAMLA
MAV_4865|M.avium_104                TYQVWQAQWNEAMESLVRAYQ--------------SMASTHEANTMSMLA
Rv3017c|M.tuberculosis_H37Rv        SHQDWQAQWNQAMEALARAYRRCRRALRQIGVLERPVGDSSDCGTIRVGS
Mb3042c|M.bovis_AF2122/97           SHQDWQAQWNQAMEALARAYRRCRRALRQIGVLERPVGDSSDCGTIRVGS
                                    :   **.*** * * : ***:              .:. : : .*  : :

MSMEG_0621|M.smegmatis_MC2_155      R----------DQAEGAKWG--
TH_2110|M.thermoresistible__bu      R----------DKAEGAKWGGM
Mflv_0323|M.gilvum_PYR-GCK          R----------DQAEGAKWG--
Mvan_0418|M.vanbaalenii_PYR-1       R----------DQAEGAKWG--
MAB_2228c|M.abscessus_ATCC_199      R----------DMAEGAKWGA-
MLBr_02531|M.leprae_Br4923          R----------DQAEAAKWGG-
MMAR_0547|M.marinum_M               R----------DTSEAAKWGG-
MUL_1210|M.ulcerans_Agy99           R----------DTSEATKWGG-
MAV_4865|M.avium_104                R----------DQAEAAKWGG-
Rv3017c|M.tuberculosis_H37Rv        FRGRWLDPRHAGPATAADAGD-
Mb3042c|M.bovis_AF2122/97           FRGRWLDPRHAGPATAADAGD-
                                               . : .:. *