For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2984 (ppk)

annotation: polyphosphate kinase
coordinates: 3339854 - 3342082
length: 742

MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLAL
AADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHA
RVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVR
QPEDGTQHFARVKVPDNVDRFVELAAREASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAF
RITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLD
LSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADP
NVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVAYGLVGLKT
HCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLL
VAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALR
PGAQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFE
SALDPCTRCWELGPDGQWTASPQEGHSVRDHQESLMERHRSP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2984ppk-100% (742)polyphosphate kinase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3008ppk0.0100.00% (742) polyphosphate kinase
M. gilvum PYR-GCKMflv_4223-0.084.15% (713) polyphosphate kinase
M. leprae Br4923MLBr_01681-0.087.87% (742) polyphosphate kinase
M. abscessus ATCC 19977MAB_3290-0.080.08% (708) polyphosphate kinase
M. marinum MMMAR_1730ppk0.089.49% (742) polyphosphate kinase Ppk
M. avium 104MAV_3834ppk0.086.12% (742) polyphosphate kinase
M. smegmatis MC2 155MSMEG_2391ppk0.082.79% (709) polyphosphate kinase
M. thermoresistible (build 8)TH_2046ppk0.082.39% (721) PROBABLE POLYPHOSPHATE KINASE PPK (POLYPHOSPHORIC ACID
M. ulcerans Agy99MUL_1972ppk0.089.08% (742) polyphosphate kinase
M. vanbaalenii PYR-1Mvan_2139-0.083.45% (731) polyphosphate kinase

CLUSTAL 2.0.9 multiple sequence alignment


Rv2984|M.tuberculosis_H37Rv         ------MMSNDRKVTEIENSPVTEVRPEEHAWYPDD-----------SAL
Mb3008|M.bovis_AF2122/97            ------MMSNDRKVTEIENSPVTEVRPEEHAWYPDD-----------SAL
MMAR_1730|M.marinum_M               ------MIGNDRWVTEIETGPVTEARPDTNAREPGD-----------RTP
MUL_1972|M.ulcerans_Agy99           ------MIGNDRWVTEIETGPVTEARPDTNAREPGD-----------RTP
MLBr_01681|M.leprae_Br4923          ------MMSNDLLVTDIEA----EARTEENIWHSDN-----------SAL
MAV_3834|M.avium_104                ------MMRHDRNVTEIDA----ETRPDENLWHSGD-----------SAV
Mflv_4223|M.gilvum_PYR-GCK          ----MTEAQTRTEPSESSE--SSEAVAP-AITSAAD-----------SAP
Mvan_2139|M.vanbaalenii_PYR-1       ----MTEAQTRPDSTEASE--ASETTPPPAVSGSAD-----------SAP
MSMEG_2391|M.smegmatis_MC2_155      MIGHVSEATEAEPANRTDEPLAQDGTARPAASGQAV-----------ATP
TH_2046|M.thermoresistible__bu      VAGDGVTAPTGADQRGADQRGADQRGADQTGADQTDRTGDERWDGSHTAP
MAB_3290|M.abscessus_ATCC_1997      ----MITRVT--------------------------------------TP
                                                                                    : 

Rv2984|M.tuberculosis_H37Rv         AAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAK
Mb3008|M.bovis_AF2122/97            AAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAK
MMAR_1730|M.marinum_M               AAPPAATPAATTDQLPEDRYLNRELSWLEFNARVLALAADDSMPLLERAK
MUL_1972|M.ulcerans_Agy99           AAPPAATPAATTDQLPEDRYLNRELSWLEFNARVLALAADDSMPLLERAK
MLBr_01681|M.leprae_Br4923          AAPPAATTSASQDQLPDDRYLNRESSWLDFNARVLALAADNSLPLLERAK
MAV_3834|M.avium_104                GAPPAATPAAMTD-LPEDRYLNRELSWLDFNARVLALADDNSLPLLERAK
Mflv_4223|M.gilvum_PYR-GCK          EAPPATTAPAIENPLPEDRYLNRELSWLDFNARVLALAADPSLPLLERAK
Mvan_2139|M.vanbaalenii_PYR-1       EAPPAATPPTVENPLPEDRYLNRELSWLDFNARVLALAADPSLPLLERAK
MSMEG_2391|M.smegmatis_MC2_155      AAPPAATSPTVDNTLPEDRYLNRELSWLDFNARVLALAADPSLPLLERAK
TH_2046|M.thermoresistible__bu      EAPPAATAPAIDDALPEDRYLNRELSWLDFNARVLALAADTSLPLLERAK
MAB_3290|M.abscessus_ATCC_1997      SVPPAATTIVSGEELPEDRYLNRELSWLDFNARVLALAADESLPILERAK
                                     .***:*. .  : **.******* ***:********* * *:*:*****

Rv2984|M.tuberculosis_H37Rv         FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQ
Mb3008|M.bovis_AF2122/97            FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQ
MMAR_1730|M.marinum_M               FLAIFASNLDEFYMVRVAGLKRRDQMGLSALSADGLTPREQLGRIGEQTQ
MUL_1972|M.ulcerans_Agy99           FLAVFASNLDEFYMVRVAGLKRRDQMGLSALSADGLTPREQLGRIGEQTQ
MLBr_01681|M.leprae_Br4923          FLAIFASNLDEFYMVRVAGLKRRDEMDLSVRSADGLTPREQLSRIGEQTQ
MAV_3834|M.avium_104                FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPRKQLALIGEHTQ
Mflv_4223|M.gilvum_PYR-GCK          FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLSPREQLRRISERTQ
Mvan_2139|M.vanbaalenii_PYR-1       FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLSPREQLRRISERTQ
MSMEG_2391|M.smegmatis_MC2_155      FLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLSPREQLRRINERTQ
TH_2046|M.thermoresistible__bu      FLAIFASNLDEFYMVRVAGLKRRHETGLSVRSADGLSPLEQLRRISERTQ
MAB_3290|M.abscessus_ATCC_1997      FLAIFASNLDEFYMVRVAGLKRRDETGLSVRSADGLSPREQLKLIGERTQ
                                    ***:*******************.: .**. *****:* :**  *.*:**

Rv2984|M.tuberculosis_H37Rv         QLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPV
Mb3008|M.bovis_AF2122/97            QLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPV
MMAR_1730|M.marinum_M               RIASRHARVFRDSVLPALGEEGIYVVTWADLDQAEREQLSTYFHEQVFPV
MUL_1972|M.ulcerans_Agy99           HIASRHARVFRDSVLPALGEEGIYVVTWADLDQAEREQLSTYFHEQVFPV
MLBr_01681|M.leprae_Br4923          WIASRHARVFLDSVLPALGEEGIYIVTWTDLDQAERDQLSTYFNEQVFPV
MAV_3834|M.avium_104                RIATRHARVFLDSVRPALAEEGIHIVTWADLDQAERDELSTYFTEQVFPV
Mflv_4223|M.gilvum_PYR-GCK          QIASRHAHVFLDSVRPALADEGIVIVTWAQLDDAERAKLSTYFHEQVFPV
Mvan_2139|M.vanbaalenii_PYR-1       QIASRHAHVFLDSVRPALAQEGIVIVNWAELDDAERGRLSTYFHEQVFPV
MSMEG_2391|M.smegmatis_MC2_155      QISFRHAAVFLDSVRPALAQQGIHIVTWAELDEDERAKLSTYFHEQVFPV
TH_2046|M.thermoresistible__bu      QLATRHADVFLNSVRPALAEEGIVIVTWAELGEAERNKLSTYFHEQVFPV
MAB_3290|M.abscessus_ATCC_1997      EISVQHARVFSESVRPELAENGIFVVTWADLSENERSYLSSYFNDQVFPV
                                     :: :** ** :** * *.::** :*.*::*.: **  **:** :*****

Rv2984|M.tuberculosis_H37Rv         LTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVE
Mb3008|M.bovis_AF2122/97            LTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVE
MMAR_1730|M.marinum_M               LTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGGQHFARVKVPDNVDRFVE
MUL_1972|M.ulcerans_Agy99           LTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGGQHFARVKVPDNVDRFVE
MLBr_01681|M.leprae_Br4923          LTPLAVDPAHPFPFVSGLSLNLAVTVKQPEDGTQHFARVKVPNNVDRFVE
MAV_3834|M.avium_104                LTPLAVDPAHPFPFVSGLSLNLAVMVRQTEDGGQHFARVKVPNNVDRFVE
Mflv_4223|M.gilvum_PYR-GCK          LTPLAVDPAHPFPFVSGLSLNLAITVKHPDDGGQHFARIKVPDNVDRFVE
Mvan_2139|M.vanbaalenii_PYR-1       LTPLAVDPAHPFPFVSGLSLNLAITVKHPDDGGQHFARIKVPDNVDRFVE
MSMEG_2391|M.smegmatis_MC2_155      LTPLAVDPAHPFPFVSGLSLNLAITVRHPDDGGQHFARIKVPDNVGRFVE
TH_2046|M.thermoresistible__bu      LTPLAVDPAHPFPFVSGLSLNLAIMVKRPEDGGQHFARVKVPDNVDRFVE
MAB_3290|M.abscessus_ATCC_1997      LTPLAVDPAHPFPYISGLSLNLAITVQVPETGGQHFARIKVPDNVDRFVR
                                    *************::********: *: .: * *****:***:**.***.

Rv2984|M.tuberculosis_H37Rv         LAAR-EASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRI
Mb3008|M.bovis_AF2122/97            LAAR-EASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRI
MMAR_1730|M.marinum_M               LGG-----TDTDGAEGAAVHRFLPVEELIAAFLPVLFPGMEIVEHHAFRI
MUL_1972|M.ulcerans_Agy99           LGG-----TDTDGAEGAAVHRFLPLEELIAAFLPVLFPGMEIVEHHAFRI
MLBr_01681|M.leprae_Br4923          LANRGAVRDTSAGDEGQLIHRFLPMEELIAAFLPVLFPGTEIVEHHAFRI
MAV_3834|M.avium_104                LAAP----RAGAEGENRGVVRFLPMEELIAAFLPLLFPGMEIVEHHAFRI
Mflv_4223|M.gilvum_PYR-GCK          LPA---------RGDSPGVVRFLPMEELIAAFLTVLFPGLEIVEHHAFRI
Mvan_2139|M.vanbaalenii_PYR-1       LAS---------REDTPRTVRFLPMEELIAAFLPVLFPGLEVVEHHAFRI
MSMEG_2391|M.smegmatis_MC2_155      LGS---------SSHDSDGVRFLPMEELIAAFLPVLFPGLEVVEHHAFRI
TH_2046|M.thermoresistible__bu      LDS---------RPGADGLIRFLPMEELIAAFLPVLFPGLEIVEHHAFRI
MAB_3290|M.abscessus_ATCC_1997      LRSP----DGTESPQAAHTARFLPMEELIAAHLSALFPGLEIVEHHAFRI
                                    *                   ****:******.*. **** *:********

Rv2984|M.tuberculosis_H37Rv         TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLL
Mb3008|M.bovis_AF2122/97            TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLL
MMAR_1730|M.marinum_M               TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVADDMTEGMLELLL
MUL_1972|M.ulcerans_Agy99           TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVADDMTEGMLELLL
MLBr_01681|M.leprae_Br4923          TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLL
MAV_3834|M.avium_104                TRNADMEVEEDRDEDLLQALERELARRRFGPPVRLEIADDMTEGMLELLL
Mflv_4223|M.gilvum_PYR-GCK          TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVSDDMTESMLELLL
Mvan_2139|M.vanbaalenii_PYR-1       TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVSDDMTEGMLELLL
MSMEG_2391|M.smegmatis_MC2_155      TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVSDDMTESMLELLL
TH_2046|M.thermoresistible__bu      TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVSDDMTENMLELLL
MAB_3290|M.abscessus_ATCC_1997      TRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEVADDMTEHMLELLL
                                    *****:************************.*****::***** ******

Rv2984|M.tuberculosis_H37Rv         RELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERE
Mb3008|M.bovis_AF2122/97            RELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERE
MMAR_1730|M.marinum_M               RELDVHPGDVIEVPGLLDLSSLWQIYGLDRPALKDRTFVPATHPAFAERE
MUL_1972|M.ulcerans_Agy99           RELDVHPGDVIEVPGLLDLSSLWQIYGLDRPALKDRTFVPATHPAFAERE
MLBr_01681|M.leprae_Br4923          RELDVHPSDVIEVPGLLDLSSLWQIYGLDRPALKDRAFIPDTHPAFAERE
MAV_3834|M.avium_104                RELDVHPGDVIEVPGLLDLSSLRQIYDLDRPALKDPAFVPDTHPAFADRE
Mflv_4223|M.gilvum_PYR-GCK          RELDVAPGDVVEVPGLLDLSSLWQIYSVDRPGLKDPPFVPATPSAFGERE
Mvan_2139|M.vanbaalenii_PYR-1       RELDVAPGDVVEVPGLLDLSSLWQIYGVDRPALKDPPFVPATPSAFGERE
MSMEG_2391|M.smegmatis_MC2_155      RELDVAPGDVIEVPGLLDLSALWQIYSVDRPDLKDRPFVPATPPAFGERE
TH_2046|M.thermoresistible__bu      RELDVHPDDVVEVPGLLDLSSLWQIYDVDRPALKDPPFVPATPPAFGERE
MAB_3290|M.abscessus_ATCC_1997      RELDVDPGDVVQVPGLLDLSCLWQVYGVDRPALKDPTFVPATHPAFGQGE
                                    ***** *.**::********.* *:* :*** *** .*:* * .**.: *

Rv2984|M.tuberculosis_H37Rv         TPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRT
Mb3008|M.bovis_AF2122/97            TPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRT
MMAR_1730|M.marinum_M               TPKSIFATLREGDVLVHHPYYSFSTSVQRFIEQAAADPNVLAIKQTLYRT
MUL_1972|M.ulcerans_Agy99           TPKSIFATLREGDVLVHHPYYSFSTSVQRFIEQAAADPNVLAIKQTLYRT
MLBr_01681|M.leprae_Br4923          TPKSIFATLREGDVLVHHPYHSFATSVQRFIEQATADPDVLAIKQTLYRT
MAV_3834|M.avium_104                SPKSIFATLREGDVLVHHPYDSFSTSVQRFIQQAAADPNVLAIKQTLYRT
Mflv_4223|M.gilvum_PYR-GCK          TPKSIFSALRDGDVLVHHPYDSFSTTVQRFIEQAAADPNVLAIKQTLYRT
Mvan_2139|M.vanbaalenii_PYR-1       TPKSIFAALRDGDVLVHHPYDSFSTTVQRFIEQAAADPNVLAIKQTLYRT
MSMEG_2391|M.smegmatis_MC2_155      TPKSIFSTLRDGDVLVHHPYDSFSTTVQRFIEQAAADPNVLAIKQTLYRT
TH_2046|M.thermoresistible__bu      TPKSIFATLRDGDVLVHHPYDSFSTTVQRFIEQAAADPNVLAIKQTLYRT
MAB_3290|M.abscessus_ATCC_1997      TPKSIFSTLRDGDVLVHHPYDSFSTSVQRFIEQAAADPQVLAIKQTLYRT
                                    :*****::**:********* **:*:*****:**:***:***********

Rv2984|M.tuberculosis_H37Rv         SGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVA
Mb3008|M.bovis_AF2122/97            SGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVA
MMAR_1730|M.marinum_M               SGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIRWARALEQAGVHVA
MUL_1972|M.ulcerans_Agy99           SGDSPIVRALIDAAEAGKQVVALVEVKARFDEQANIRWARALEQAGVHVA
MLBr_01681|M.leprae_Br4923          SGDSPIVLALIEAAEAGKQVVALVEIKARFDEQANIRWARALEHAGVHVV
MAV_3834|M.avium_104                SGDSPIVRALIEAAEAGKQAVALVEIKARFDEQANIRWARALEQAGVHVV
Mflv_4223|M.gilvum_PYR-GCK          SGDSPIVNALIDAAEAGKQVVALVEIKARFDEQANIKWARALEQAGVHVV
Mvan_2139|M.vanbaalenii_PYR-1       SGDSPIVNALIDAAEAGKQVVALVEIKARFDEQANIKWARALEQAGVHVV
MSMEG_2391|M.smegmatis_MC2_155      SGDSPIVNALIDAAEAGKQVVALVEIKARFDEQANIKWARTLEQAGVHVV
TH_2046|M.thermoresistible__bu      SGDSPIVNALIDAAEAGKQVVALVEIKARFDEQANIKWARTLEQAGVHVV
MAB_3290|M.abscessus_ATCC_1997      SGDSPIVNSLIDAAEAGKQVVALVEIKARFDEQANIKWARALEDAGVHVV
                                    ******* :**:*******.*****:********** ***:**.*****.

Rv2984|M.tuberculosis_H37Rv         YGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTA
Mb3008|M.bovis_AF2122/97            YGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTA
MMAR_1730|M.marinum_M               YGIVGLKTHCKTALVVRREGPVIRRYCHIGTGNYNSKTARLYEDVGLLTA
MUL_1972|M.ulcerans_Agy99           YGIVGLKTHCKTALVVRREGPVIRRYCHIGTGNYNSKTARLYEDVGLLTA
MLBr_01681|M.leprae_Br4923          YGIVGLKTHCKTCLVVRREGPTIRRYCHIGTGNYNSKTARLYEDVGLLTA
MAV_3834|M.avium_104                YGLVGLKTHCKTCLVVRREGSAIRRYCHIGTGNYNSKTARLYEDVGLLTA
Mflv_4223|M.gilvum_PYR-GCK          YGLIGLKTHCKTCLVVRREGSTIRRYCHIGTGNYNPKTARLYEDIGLLTA
Mvan_2139|M.vanbaalenii_PYR-1       YGLIGLKTHCKTCLVVRREGSTIRRYCHVGTGNYNPKTARLYEDIGLLTA
MSMEG_2391|M.smegmatis_MC2_155      YGLIGLKTHCKTCLVVRREGSAIRRYCHIGTGNYNPKTARLYEDVGLLTA
TH_2046|M.thermoresistible__bu      YGIIGLKTHCKCALVVRREGSVIRRYCHIGTGNYNPKTARLYEDIGLLTA
MAB_3290|M.abscessus_ATCC_1997      YGLIGLKTHCKTALVVRREGSAIRRYCHIGTGNYNPKTARLYEDVGLLTS
                                    **::******* .*******..******:******.********:****:

Rv2984|M.tuberculosis_H37Rv         APDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHR
Mb3008|M.bovis_AF2122/97            APDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHR
MMAR_1730|M.marinum_M               APDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIERVEREVAAHL
MUL_1972|M.ulcerans_Agy99           APDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIERVEREVAAHL
MLBr_01681|M.leprae_Br4923          APDIGADLTDLFNSLTGYSRKLAYRNLLVAPYGIRRGIIERVEREVAAHR
MAV_3834|M.avium_104                APDIGADLTDLFNSLTGYSRKVSYRNLLVAPHGIRTGIIERVEREIAAHR
Mflv_4223|M.gilvum_PYR-GCK          APDIGADLTDLFNSLTGYSRKESYRNLLVAPYGVRRGIIERIDREIAATR
Mvan_2139|M.vanbaalenii_PYR-1       APDIGADLTDLFNSLTGYSRKESYRNLLVAPYGVRKGIIERIEREIAATR
MSMEG_2391|M.smegmatis_MC2_155      DPDIGADLTDLFNSLTGYSRKDSYRNLLVAPRGVRKGIIERIDREIAAQH
TH_2046|M.thermoresistible__bu      APDIGADLTDLFNSLTGYSRKESYRNLLVAPYGVRKGLIDRIEGEIAAKR
MAB_3290|M.abscessus_ATCC_1997      APEIGADLTDLFNSLTGYSRKVSYRNLLVAPQGIRAGIVERIDREIAAHR
                                     *:****************** :******** *:* *:::*:: *:**  

Rv2984|M.tuberculosis_H37Rv         AEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPG
Mb3008|M.bovis_AF2122/97            AEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPG
MMAR_1730|M.marinum_M               EHGPQAGKGHIRLKMNALVDEQVIDALYRASQVGVRIEVVVRGICALRPG
MUL_1972|M.ulcerans_Agy99           EHGPQAGKGHIRLKMNALVDEQVTDALYRASQVGVRIEVVVRGICALRPG
MLBr_01681|M.leprae_Br4923          ESGPQTGKGLIRLKMNALVDEQVIDALYRASQAGVRVEVVVRGICALRPG
MAV_3834|M.avium_104                ERG----QGRIRLKMNALVDEQVIDSLYRASQAGVRVEVVVRGICALRPG
Mflv_4223|M.gilvum_PYR-GCK          DGA----EGRIRLKANALVDEQVIDALYRASQAGVQVEVVVRGICALRPG
Mvan_2139|M.vanbaalenii_PYR-1       DGA----EGRIRLKANALVDEQVIDALYRASQAGVRVEVVVRGICALRPG
MSMEG_2391|M.smegmatis_MC2_155      AGA----QTGIRLKANALVDEQVIDALYRASQAGIPVDIVVRGICALRPG
TH_2046|M.thermoresistible__bu      EGA----DAHIRLKANALVDEQIIDALYRASLAGVGVEVVVRGICALRPG
MAB_3290|M.abscessus_ATCC_1997      AGQ----EARIRLKMNALVDEQVIDALYRASRAGVPIEVVVRGICALRPG
                                           .  **** *******: *:***** .*: :::***********

Rv2984|M.tuberculosis_H37Rv         AQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEV
Mb3008|M.bovis_AF2122/97            AQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEV
MMAR_1730|M.marinum_M               AEGFSENITARSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEV
MUL_1972|M.ulcerans_Agy99           AEGFSENITARSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEV
MLBr_01681|M.leprae_Br4923          TEGFSENIFVRSILGRFLEHSRIIHFRAIDEFWIGSADMMHRNLDRRVEV
MAV_3834|M.avium_104                VQGYSENIFVRSILGRFLEHSRIIHFRNINEFWIGSADMMHRNLDRRVEV
Mflv_4223|M.gilvum_PYR-GCK          EPGFSDNITVRSILGRFLEHSRIIHFRAIDEYWIGSADMMHRNLDRRVEV
Mvan_2139|M.vanbaalenii_PYR-1       EPGFSENIAVRSILGRFLEHSRIIHFRAIDEYWIGSADMMHRNLDRRVEV
MSMEG_2391|M.smegmatis_MC2_155      VPGYSDNITVRSILGRFLEHSRIIHFRGINEFWIGSADMMHRNLDRRVEV
TH_2046|M.thermoresistible__bu      VPGLSENIRVRSILGRFLEHSRILHFRAQNEFWIGSADMMHRNLDRRVEV
MAB_3290|M.abscessus_ATCC_1997      VPEYSGSITVRSILGRFLEHSRIIHFNAIDEFWIGSADMMHRNLDRRVEV
                                        * .* .*************:**.  :*:******************

Rv2984|M.tuberculosis_H37Rv         MAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQ
Mb3008|M.bovis_AF2122/97            MAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQ
MMAR_1730|M.marinum_M               MAQVKDPRLTAQLDDLFESALDPATRCWELGPDGQWTASPQEGRTVRDHQ
MUL_1972|M.ulcerans_Agy99           MAQVKDPRLTAQLDDLFESALDPATRCWELGPDGQWTASPQEGRTVRDHQ
MLBr_01681|M.leprae_Br4923          LAQVKDSRLTAQLDELLKSALDPFTRCWELRPDGQWTASPQKGQQVRDHQ
MAV_3834|M.avium_104                LAQVKDPKLTAQLDELFESALDPSTRCWELGPDGQWTPSPQEGHTVRDHQ
Mflv_4223|M.gilvum_PYR-GCK          MAQVKDPRLTTQLNDIFDSAADPRTRCWELGSDGHWTALPQEGHSVRDHQ
Mvan_2139|M.vanbaalenii_PYR-1       MAQVKDPRLTAQLNDIFESATDPGTRCWELGSDGHWTASPQEGRTVRDHQ
MSMEG_2391|M.smegmatis_MC2_155      MAQVKDPRLTAQLNEVFESAMDPATRCWELRHDSHWVALPQEGQTVRDHQ
TH_2046|M.thermoresistible__bu      MAQVKDPRLTAQLNDILDSALDPATRCWELGPDGRWTPSPREGETVRDHQ
MAB_3290|M.abscessus_ATCC_1997      LARVTDPKLTAQLDDMFTSALDSHTRCWELQPDGQWLASPADGEEVRDHQ
                                    :*:*.:.:**:**:::: ** *. ******  *.:* . * .*. *****

Rv2984|M.tuberculosis_H37Rv         ESLMERHRSP-
Mb3008|M.bovis_AF2122/97            ESLMERHRSP-
MMAR_1730|M.marinum_M               VSLMERHRSP-
MUL_1972|M.ulcerans_Agy99           VSLMERHRSP-
MLBr_01681|M.leprae_Br4923          ESLMERHRSR-
MAV_3834|M.avium_104                VSLMERHRSP-
Mflv_4223|M.gilvum_PYR-GCK          ISLMERRRHP-
Mvan_2139|M.vanbaalenii_PYR-1       RSLMERHRHP-
MSMEG_2391|M.smegmatis_MC2_155      VSLMERHRQP-
TH_2046|M.thermoresistible__bu      VSMMKRRRYH-
MAB_3290|M.abscessus_ATCC_1997      VEMMKRHRSQT
                                     .:*:*:*