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M. tuberculosis H37Rv Rv2968c (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 3323071 - 3323703
length: 210

VAARPAERSGDPAAVRVPVPSAWWVLIGGVIGLFASMTLTVEKVRILLDPIYVPSCNVNPIVSCGSVMTT
PQASLLGFPNPLLGIAGFTVVVVTGVLAVAKVPLPRWYWIGLAVGILVGVAFVHWLIFQSLYRIGALCPY
CMVVWAVIATLLVVVASIVFGPMRENRGSQERVGARLLYQWRWSLATLWFTTVFLLIMVRFWDYWSTLI*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2968c--100% (210)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2992c-1e-122100.00% (210) integral membrane protein
M. gilvum PYR-GCKMflv_4201-5e-7766.34% (205) vitamin K epoxide reductase
M. leprae Br4923MLBr_01666-1e-8872.43% (214) hypothetical protein MLBr_01666
M. abscessus ATCC 19977MAB_3268c-2e-7264.55% (189) hypothetical protein MAB_3268c
M. marinum MMMAR_1748-1e-8671.63% (215) integral membrane protein
M. avium 104MAV_3812-8e-8271.72% (198) integral membrane protein
M. smegmatis MC2 155MSMEG_2411-6e-7462.56% (211) integral membrane protein
M. thermoresistible (build 8)TH_1230-5e-6965.57% (183) PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. ulcerans Agy99MUL_1991-5e-8771.16% (215) integral membrane protein
M. vanbaalenii PYR-1Mvan_2164-5e-7868.34% (199) vitamin K epoxide reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4201|M.gilvum_PYR-GCK          MTVTATDSVDHADPSADEATGVAVARGSALWVLIAGVVGLAAALTLTVEK
Mvan_2164|M.vanbaalenii_PYR-1       MTVAAAGSVDHTDPSAPEPASVAVARGSALWVLIGGVIGLAAALTLTIEK
TH_1230|M.thermoresistible__bu      -----------------------VGR----RXXIAGVLGLAAAIALTIEK
MSMEG_2411|M.smegmatis_MC2_155      MTVAAS---DTDRSVAEGPGGLVVGKPSAVWVLIAGVLGLAASLTLTVEK
MAB_3268c|M.abscessus_ATCC_199      ---------------------MTLRPATAWYVLVAGVAGLAAALALTIEK
Rv2968c|M.tuberculosis_H37Rv        -MVAARPAERSGD----PAAVR-VPVPSAWWVLIGGVIGLFASMTLTVEK
Mb2992c|M.bovis_AF2122/97           -MVAARPAERSGD----PAAVR-VPVPSAWWVLIGGVIGLFASMTLTVEK
MLBr_01666|M.leprae_Br4923          --MSAQPVERPGDLKPAPASVLPMPVPTAWWVLIAGVIGLVASMMLTVEK
MMAR_1748|M.marinum_M               -MVSADSAERSSDLTSGAVRQVHVPMLSAWWVLICGVTGLLASGALTVEK
MUL_1991|M.ulcerans_Agy99           -MVSADSAERSSDLTSGAVRQVHVPMASAWWVLICGVTGLLASGALTVEK
MAV_3812|M.avium_104                -MTGAVATEATGLTPDSPAGPA-VPALSAWSVLVAGVIGLVASVTLTLEK
                                                           :         : ** ** *:  **:**

Mflv_4201|M.gilvum_PYR-GCK          IELLIDPDYIPSCSINPVLSCGSVMITPQASLFGFPNPLIGIVSFTVVVV
Mvan_2164|M.vanbaalenii_PYR-1       IELLIDPDYIPTCSINPVLSCGSVMITPQASLFGFPNPLLGIVAFSVVVV
TH_1230|M.thermoresistible__bu      VALLIDPDYVPTCSLNPVLSCGSVMVTPQASVFGFPNSLIGVVSFTVVTV
MSMEG_2411|M.smegmatis_MC2_155      IELLINPDYVPSCSINPVLSCGSVMVTWQASLFGFPNPLIGIVAFSVVLV
MAB_3268c|M.abscessus_ATCC_199      IEILIDPTYVPSCSLNPVISCGSVMTTEQASAFGFPNSLIGIVAFTVVLV
Rv2968c|M.tuberculosis_H37Rv        VRILLDPIYVPSCNVNPIVSCGSVMTTPQASLLGFPNPLLGIAGFTVVVV
Mb2992c|M.bovis_AF2122/97           VRILLDPIYVPSCNVNPIVSCGSVMTTPQASLLGFPNPLLGIAGFTVVVV
MLBr_01666|M.leprae_Br4923          IRILLNSAYVPSCNVNPIVACGSVMSTPQASVLGFPNPLLGIVGFTLVTV
MMAR_1748|M.marinum_M               VRILLDPSYVPACNINPIVSCGSVMTTAQASLLGFPNQLFGIAAFTVVVV
MUL_1991|M.ulcerans_Agy99           VRILFDPSYVPACNINPIVSCGSVMTTAQASLLGFPNQLFGIAAFTVVVV
MAV_3812|M.avium_104                IDILLDPAYVPSCNINPILSCGSVMITPQASLLGFPNPLLGLVAFTVVVV
                                    : :*::. *:*:*.:**:::***** * *** :**** *:*:..*::* *

Mflv_4201|M.gilvum_PYR-GCK          TGVLALAKVSLPRWYWAGLAVATLLGTVFVHWLIFQSLYRIGALCPYCMV
Mvan_2164|M.vanbaalenii_PYR-1       TGVLAVAKVNLPRWYWAGLSVGTLLGAVFVHWLIFQSLYRIGALCPYCMV
TH_1230|M.thermoresistible__bu      TGVLALAGIRLPRWYWGGLATGTLFGTVFVHWLIFQSLYRIEALCPYCMV
MSMEG_2411|M.smegmatis_MC2_155      TGVLAVAGVRLPRWYWAGLATGTALGAVFVHWLIFQSLYRIGALCPYCMV
MAB_3268c|M.abscessus_ATCC_199      TGVLSVAGVQLPRWYWSGLAIGSLLGAVFVHWLIFQSLYRIGALCPYCMV
Rv2968c|M.tuberculosis_H37Rv        TGVLAVAKVPLPRWYWIGLAVGILVGVAFVHWLIFQSLYRIGALCPYCMV
Mb2992c|M.bovis_AF2122/97           TGVLAVAKVPLPRWYWIGLAVGILVGVAFVHWLIFQSLYRIGALCPYCMV
MLBr_01666|M.leprae_Br4923          TGVLSVAEVSLPQWYWIGLAVGTLAGVGFVHWLIFQSLYRIGALCAYCMV
MMAR_1748|M.marinum_M               TGVLAVTKVPLPRWYWVGLTIGVLVGTVFVHWLIFESLYRIGSLCPYCMV
MUL_1991|M.ulcerans_Agy99           TGVLAVTKVPLPRWYWVGLTIGVLVGTVFVHWLIFESLYRIGSLCPYCMV
MAV_3812|M.avium_104                TGLLAVTKVVLPQWYWIGLTAGLVVGAVFVHWLIFQSLYRIGALCPYCMV
                                    **:*::: : **:*** **: .   *. *******:***** :**.****

Mflv_4201|M.gilvum_PYR-GCK          VWAVTIPLLVVATSVAVQAQR--SGNA----AVRLIYTWRWSLVTLWFTG
Mvan_2164|M.vanbaalenii_PYR-1       VWAVTIPLLVVTASIALQAPR--SGSA----VVRALYTWRWSLVTLWFTG
TH_1230|M.thermoresistible__bu      VWAVTIPLLVVTASVALQPAG--HTSP----VARALYQWRWSLTALWFTA
MSMEG_2411|M.smegmatis_MC2_155      VWAVTIPLAVVTAVIALRARAGDADAG----PGNIVHQWRWSLVALWFTA
MAB_3268c|M.abscessus_ATCC_199      VWSVTIPLLVVSASIALRPLG---SHR----WARILYQWRWSLVVFWFVA
Rv2968c|M.tuberculosis_H37Rv        VWAVIATLLVVVASIVFGPMR-ENRGSQERVGARLLYQWRWSLATLWFTT
Mb2992c|M.bovis_AF2122/97           VWAVIATLLVVVASIVFGPMR-ENRGSQERVGARLLYQWRWSLATLWFTT
MLBr_01666|M.leprae_Br4923          IWAVSVSLLVVVTAIVFRPLL-EVLPGRTSAIARGIYQWRWSIATLWFIT
MMAR_1748|M.marinum_M               VWIITATLLVVVGSIAFRPDP-DSTSG---AAVRVLFQWRWSIATLWLTA
MUL_1991|M.ulcerans_Agy99           VWIITATLLVVVGSIAFRPDP-DSTGG---AAVRVLFQWRWSIATLWLTA
MAV_3812|M.avium_104                VWVVTIALLVVVASIAYRPALGDSRSG----PGWLLFQWRWSIVALWFTA
                                    :* :  .* **   :.  .                :. ****:..:*:  

Mflv_4201|M.gilvum_PYR-GCK          VLLLILERFWNYWSTLI
Mvan_2164|M.vanbaalenii_PYR-1       VALLILERFWNYWSTLV
TH_1230|M.thermoresistible__bu      LFLLILVQFWSYWSTLV
MSMEG_2411|M.smegmatis_MC2_155      LVLLILVRFWEYWSTLL
MAB_3268c|M.abscessus_ATCC_199      LVLAILERFWDYWITLV
Rv2968c|M.tuberculosis_H37Rv        VFLLIMVRFWDYWSTLI
Mb2992c|M.bovis_AF2122/97           VFLLIMVRFWDYWSTLI
MLBr_01666|M.leprae_Br4923          VFLLIMVRFWNYWQTLL
MMAR_1748|M.marinum_M               VFLLIMVRFWNYWSTLL
MUL_1991|M.ulcerans_Agy99           VFLLIMVRFWNYWSTLL
MAV_3812|M.avium_104                VFLLIMVRFWDYWSTLL
                                    : * *: :**.** **: