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WEGLWIATAVIAALVVIAALTLGLVLYRRRRISLSPRPERGVVDRSGGYTASSGITFSQTPTTQPAERID TSGLPAVGDDATVPRDAPKRTIADVHLPEFEPEPQAPEVPEADAIAPPEGRLERLRGRLARSQNALGRGL LGLIGGGDLDEDSWQDVEDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQPGMD RSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGAADTFRAAAADQLQTWAARVGAAV VRGPEGADPASVAFDAVDKGIAAGADVVLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATI GQNGLAQARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDLAPFEPAAFVDALL G*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2921c | ftsY | - | 100% (422) | PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL RECOGNITION PARTICLE RECEPTOR) |
| M. tuberculosis H37Rv | Rv2916c | ffh | 3e-33 | 33.89% (298) | signal recognition particle protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2945c | ftsY | 0.0 | 100.00% (422) | cell division protein FtsY |
| M. gilvum PYR-GCK | Mflv_4186 | - | 1e-180 | 72.98% (470) | signal recognition particle-docking protein FtsY |
| M. leprae Br4923 | MLBr_01628 | - | 0.0 | 81.35% (429) | putative SRP family of GTP-binding protein |
| M. abscessus ATCC 19977 | MAB_3241c | - | 1e-162 | 67.10% (462) | cell division protein FtsY-like protein |
| M. marinum M | MMAR_1786 | ftsY | 0.0 | 81.22% (458) | cell division protein FtsY |
| M. avium 104 | MAV_3776 | ftsY | 0.0 | 86.25% (429) | signal recognition particle-docking protein FtsY |
| M. smegmatis MC2 155 | MSMEG_2424 | ftsY | 1e-175 | 67.76% (490) | signal recognition particle-docking protein FtsY |
| M. thermoresistible (build 8) | TH_1481 | ftsY | 1e-178 | 70.95% (475) | PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL |
| M. ulcerans Agy99 | MUL_2034 | ftsY | 0.0 | 81.10% (455) | cell division protein FtsY |
| M. vanbaalenii PYR-1 | Mvan_2177 | - | 0.0 | 75.78% (450) | signal recognition particle-docking protein FtsY |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2921c|M.tuberculosis_H37Rv MWEGLWIATA---VIAALVVIAALTLGLVLYRRRRISLSPR-------PE
Mb2945c|M.bovis_AF2122/97 MWEGLWIATA---VIAALVVIAALTLGLVLYRRRRISLSPR-------PE
MMAR_1786|M.marinum_M MSEGLWVAIA---VIAALLVIVALVVGLLRYRRRRISLAAR-------PE
MUL_2034|M.ulcerans_Agy99 MSEGLWVAIA---VIAALLVIVALVVGLLRYRRRRISLAAR-------PE
MAV_3776|M.avium_104 MSQGLWIAVAVLVVIAVLVVIAALVLGLARYRRRRISFSTR-------PE
MLBr_01628|M.leprae_Br4923 MSEGLWIATA---VAAVLVVIAALILGSVRYRRRRISLIFSS----LSSG
Mflv_4186|M.gilvum_PYR-GCK MSEGLWIAIA----VIAVLLVVALVVGLVRYRRRQIKLSAP-------DT
Mvan_2177|M.vanbaalenii_PYR-1 MSEGLWIAIA----VIAVLLLVALVVGLVRYRRRRISLSAP-------DT
TH_1481|M.thermoresistible__bu VSEGLWIAIA----IIAVVLVAALIVGLVLYRRRRIRLTKR-------DE
MSMEG_2424|M.smegmatis_MC2_155 -MIGLWVAIA----VVAVLLVVAIVVGLVRYRRRKIKLSAP-------EP
MAB_3241c|M.abscessus_ATCC_199 MPLEVWIAIA----IVAVVVVAALVFGLVRYRSRRISLTRSDKNTGITEG
:*:* * .::::.*: .* ** *:* :
Rv2921c|M.tuberculosis_H37Rv RGVVDRSGGYTASSGITFSQTP-TTQPAE----------RIDTSGLPAVG
Mb2945c|M.bovis_AF2122/97 RGVVDRSGGYTASSGITFSQTP-TTQPAE----------RIDTSGLPAVG
MMAR_1786|M.marinum_M VESKDRSGGYTASSGITFSQTPTTTEPAD----------RIDTSGLPAVG
MUL_2034|M.ulcerans_Agy99 VESKDRSGGYTASSGITFSQTPTTTEPAD----------RIDTSGLPAVG
MAV_3776|M.avium_104 PGAIDRSGGYTASSGITFSQAP-TAQPAE----------RLDTTGLPAVG
MLBr_01628|M.leprae_Br4923 PSASDRSGSYTASSGITFSQTALPVQPAD----------RIDTGELPAVG
Mflv_4186|M.gilvum_PYR-GCK ATPVDRSGGYTASSSITFTQSA-PVKEPPAPPKEPQRPRRLDTTGLPAVG
Mvan_2177|M.vanbaalenii_PYR-1 ATPVDRSGGYTATSGITFAQST-PVQAP------PRAPERIDTTGLPAVG
TH_1481|M.thermoresistible__bu AKPVERGGGYTTSSGITFSQSATPTKAPP----TKAAPERIDTTGLPGVG
MSMEG_2424|M.smegmatis_MC2_155 KKTIDRSGGYTASSGITFSQGG---TAPP--------AERIDTTGLPAVG
MAB_3241c|M.abscessus_ATCC_199 ATPTDRSGGYTAGSTITFSEGG--AQAAP----------------LPTVG
:*.*.**: * ***:: . ** **
Rv2921c|M.tuberculosis_H37Rv DDATVPRDAPKRTIADVHLPEF-----------------------EPEP-
Mb2945c|M.bovis_AF2122/97 DDATVPRDAPKRTIADVHLPEF-----------------------EPEP-
MMAR_1786|M.marinum_M DDATIPRDAPKRTISEVHLPEI-----------------------EPEPE
MUL_2034|M.ulcerans_Agy99 DDATIPRDAPKRTISEVHLPEI-----------------------EPEPE
MAV_3776|M.avium_104 DDATVPRDAPRRTISEVELPEP-----------------------ETPAA
MLBr_01628|M.leprae_Br4923 DDATVPRDSPRHTISDVLLPES-----------------------ELITS
Mflv_4186|M.gilvum_PYR-GCK DDATIPRDAPKRPIADVRLPEPPVVEPAPAP-----------APPEPVAE
Mvan_2177|M.vanbaalenii_PYR-1 DDATIPRDAPKRPIADVRLPEPPVLP------------------PEPVVV
TH_1481|M.thermoresistible__bu DDATIPRDAPKRPIADVRLPEPPAAPPKPPPPAEVPP---TEPPAPPVAT
MSMEG_2424|M.smegmatis_MC2_155 DDATIPRDAPKRPIADVQLPEPAVEPEAPPARDSVAAPPEAPAPPEPVAE
MAB_3241c|M.abscessus_ATCC_199 DDAEIPRDAPRRTISNVQLPEPAAEP-------------------EPVEV
*** :***:*::.*::* ***
Rv2921c|M.tuberculosis_H37Rv ------------------------------------------QAPEVP--
Mb2945c|M.bovis_AF2122/97 ------------------------------------------QAPEVP--
MMAR_1786|M.marinum_M TPAPVA--------AEPVAPPVAPETPQAPEAPEAPEAPEAPEAPEVA--
MUL_2034|M.ulcerans_Agy99 TPAPVA--------AEPVAPPVAPETPQA---PEVPEAPEAPEAPEVA--
MAV_3776|M.avium_104 P---------------------------------------APEAPAP---
MLBr_01628|M.leprae_Br4923 P---------------------------------------DEPEAAVP--
Mflv_4186|M.gilvum_PYR-GCK PE--------------PVAEPEPLPEIQ--VPEPVAEPEQVTEAPAPD--
Mvan_2177|M.vanbaalenii_PYR-1 PE--------------PVTEAP---------EPAVAEVGEAPEPPGPQ--
TH_1481|M.thermoresistible__bu PS--------------PAETAPPVEPEA--APETTPEPEPGAAPAAPQ--
MSMEG_2424|M.smegmatis_MC2_155 PAPEPAPEAAPETTAEPVTEPEPVVEAAPEVTPPVTETAPVEAPPAAPGA
MAB_3241c|M.abscessus_ATCC_199 SEP------------AETAEAAEAAVPGETVAEAAPEPEPEPEPAPKP--
.
Rv2921c|M.tuberculosis_H37Rv ---EADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDV
Mb2945c|M.bovis_AF2122/97 ---EADAIAPPEGRLERLRGRLARSQNALGRGLLGLIGGGDLDEDSWQDV
MMAR_1786|M.marinum_M ---EAEVIEPPEGRLERLRGRLAKSQNALGRSVLGLIGGGDLDEDSWQDV
MUL_2034|M.ulcerans_Agy99 ---EAEVIEPPEGRLERLRGRLAKSQNALGRSVLGLIGGGDLDEDSWQDV
MAV_3776|M.avium_104 ---EIEEIAPTEGRLERLRGRLARSQNALGRSLLGLIGGGDLDEDAWQDV
MLBr_01628|M.leprae_Br4923 ---HIDAIVPPEGRLDRLRGRLARTQNAFGRSILGLIVGGDLDEDSWQEL
Mflv_4186|M.gilvum_PYR-GCK ----IDAIAPTEGRLDRMRGRLAKSQNTLGRSMLGLIGGGDLDEDSWEEV
Mvan_2177|M.vanbaalenii_PYR-1 ----IEEIAPTEGRLDRLRGRLSKSQSTLGRSMLGLLGGGDLDEDSWEEI
TH_1481|M.thermoresistible__bu ----LDEIAPAEGRLDRLRGRLAKSQTAIGRSMLGLLGGGDLDEESWEEI
MSMEG_2424|M.smegmatis_MC2_155 TPSAIEEIAPAEGRLGRLRGRLAKSQNALGRSMLGLLGGGDLDEESWEEV
MAB_3241c|M.abscessus_ATCC_199 -EPVLDDIAPVAGRLDRLRGRLASSQNAVGRGLLGLLGAGDLDEESWEEV
: * * *** *:****: :*.:.**.:***: .*****::*:::
Rv2921c|M.tuberculosis_H37Rv EDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQP
Mb2945c|M.bovis_AF2122/97 EDTLLVADLGPAATASVVSQLRSRLASGNVRTEADARAVLRDVLINELQP
MMAR_1786|M.marinum_M EDTLLVADLGPVVTEAVVSQLRSRLASGNVRSEDDARAVLRDVLIKALQP
MUL_2034|M.ulcerans_Agy99 EDTLLVADLGPVVTEAVVSQLRSRLASGNVRSEDDARAVLRDVLIKALQP
MAV_3776|M.avium_104 EDTLLVADLGPVVTESVIAQLRGRLASSDVRTEADAKAVLRDVLINELRP
MLBr_01628|M.leprae_Br4923 EDTLLVADLGPVATESVMSALRSRLLNSNVHTESDARTMLRDVLISELQP
Mflv_4186|M.gilvum_PYR-GCK EDTLLIADLGPVVTESVVTALRAKMASSKVRTEADARAVLREVLIAELQP
Mvan_2177|M.vanbaalenii_PYR-1 EDTLLIADLGPVVTESVVTSLRAKMAASQVRTEADARAVLREVLIAELRP
TH_1481|M.thermoresistible__bu EDTLLIADLGPVVTTSVVEKLREQMAASRVRTEADARAVLREVLISELRP
MSMEG_2424|M.smegmatis_MC2_155 EDTLLIADLGPVVTESVIGALRTEMAAKNVRTEADARAVLREVLMAELRP
MAB_3241c|M.abscessus_ATCC_199 EDTLLIADLGTAVTASIVDRLRSEMAARSVRTEAQARALLREVLIDELQP
*****:****...* ::: ** .: *::* :*:::**:**: *:*
Rv2921c|M.tuberculosis_H37Rv GMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
Mb2945c|M.bovis_AF2122/97 GMDRSIRALPHAGHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MMAR_1786|M.marinum_M DMDRSIRALPHPDHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MUL_2034|M.ulcerans_Agy99 DMDRSIRALPHPDHPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MAV_3776|M.avium_104 DLDRSIRALPHADHPSVLLIVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MLBr_01628|M.leprae_Br4923 DMDRSIRALPHADHPAVLLIVGVNGTGKTTTVGKLARVLVADGRRVVLGA
Mflv_4186|M.gilvum_PYR-GCK DLDRAIRALPHADKPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
Mvan_2177|M.vanbaalenii_PYR-1 DLDRSIKALPHADKPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
TH_1481|M.thermoresistible__bu DLDRSVKALPHDDKPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MSMEG_2424|M.smegmatis_MC2_155 ELPRSIRALPHADKPSVLLVVGVNGTGKTTTVGKLARVLVADGRRVVLGA
MAB_3241c|M.abscessus_ATCC_199 ELDRSIKALPHNDKPSVLLIVGVNGTGKTTTVGKLARVLVADGRRVVLGA
: *:::**** .:*:***:******************************
Rv2921c|M.tuberculosis_H37Rv ADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADV
Mb2945c|M.bovis_AF2122/97 ADTFRAAAADQLQTWAARVGAAVVRGPEGADPASVAFDAVDKGIAAGADV
MMAR_1786|M.marinum_M ADTFRAAAAVQLQTWAARVGAEVVSGAEGADPASVAFDAVDKGVAAGADV
MUL_2034|M.ulcerans_Agy99 ADTFRAAAAVQLQTWAARVGAEVVSGAEGADPASVAFDAVDKGVAAGADV
MAV_3776|M.avium_104 ADTFRAAAADQLQTWASRVGAEVVRGAEGADPASVAFDAVDQGIAAGADV
MLBr_01628|M.leprae_Br4923 ADTFRAAAADQLQTWASRVGAELVRGVEGADPASVAFDAVDKGIGAGADV
Mflv_4186|M.gilvum_PYR-GCK ADTFRAAAADQLQSWASRVGAQVVRGPEGADPASVAFDAVDTGIASGADV
Mvan_2177|M.vanbaalenii_PYR-1 ADTFRAAAADQLQSWASRVGAQVVRGPEGADPASVAFDAVDTGIAAGADV
TH_1481|M.thermoresistible__bu ADTFRAAAADQLETWASRVGAEVVRGREGADPASVAFDAVDTGIKNGADV
MSMEG_2424|M.smegmatis_MC2_155 ADTFRAAAADQLQTWGSRVGAEVVRGPEGADPASVAFDAVDHGISAGADV
MAB_3241c|M.abscessus_ATCC_199 ADTFRAAAADQLQAWGQRVGAQVVRGAEGADPASVAFDAVDAGIREGADV
********* **::*. **** :* * ************** *: ****
Rv2921c|M.tuberculosis_H37Rv VLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQ
Mb2945c|M.bovis_AF2122/97 VLIDTAGRLHTKVGLMDELDKVKRVVTRRASVDEVLLVLDATIGQNGLAQ
MMAR_1786|M.marinum_M VLIDTAGRLHTKVGLMDELGKVKRVVTRRAAVDEVLLVLDATIGQNGLAQ
MUL_2034|M.ulcerans_Agy99 ILIDTAGRLHTKVGLMDELGKVKRLVTRRAAVDEVLLVLDATIGQNGLAQ
MAV_3776|M.avium_104 VLIDTAGRLHTKVGLMDELDKVKRVVTRRAAVDEVLLVLDATIGQNGLAQ
MLBr_01628|M.leprae_Br4923 VVIDTAGRLHTKVGLMDELDKIKRVVTRRAAVDEVLLVLDATIGQNGLTQ
Mflv_4186|M.gilvum_PYR-GCK VVVDTAGRLHTKTGLMDELGKVKRVVSKRAEVDEVLLVLDATIGQNSLPQ
Mvan_2177|M.vanbaalenii_PYR-1 VVIDTAGRLHTKTGLMDELGKVKRVVGKRAAVDEVLLVLDATIGQNSLPQ
TH_1481|M.thermoresistible__bu VLIDTAGRLHTKTGLMDELGKVKRVVKKRAAVDEVLLVLDATIGQNSLPQ
MSMEG_2424|M.smegmatis_MC2_155 VVVDTAGRLHTKTGLMDELGKVKRVVEKRAAVDEVLLVLDATIGQNSLPQ
MAB_3241c|M.abscessus_ATCC_199 VVVDTAGRLHTKTGLMDELGKIKRVVERRADVDEVLLVLDSTIGQNGLAQ
:::*********.******.*:**:* :** *********:*****.*.*
Rv2921c|M.tuberculosis_H37Rv ARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
Mb2945c|M.bovis_AF2122/97 ARVFAEVVDISGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MMAR_1786|M.marinum_M AKVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MUL_2034|M.ulcerans_Agy99 AKVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MAV_3776|M.avium_104 ARVFAEVVEITGAVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MLBr_01628|M.leprae_Br4923 VRVFAEVVDITGAVLTKLDGTAKGGIVFRIQRELGVPVKLVGLGEGPDDL
Mflv_4186|M.gilvum_PYR-GCK ARVFAEAVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
Mvan_2177|M.vanbaalenii_PYR-1 ARVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
TH_1481|M.thermoresistible__bu AKVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MSMEG_2424|M.smegmatis_MC2_155 AKVFAEVVDITGVVLTKLDGTAKGGIVFRVQQELGVPVKLVGLGEGPDDL
MAB_3241c|M.abscessus_ATCC_199 ARVFADVVDITGVALTKLDGTAKGGIVFHVQRELGVPVKLVGLGEGPDDL
.:***:.*:*:*..**************::*:******************
Rv2921c|M.tuberculosis_H37Rv APFEPAAFVDALLG
Mb2945c|M.bovis_AF2122/97 APFEPAAFVDALLG
MMAR_1786|M.marinum_M APFEPAAFVDALLG
MUL_2034|M.ulcerans_Agy99 APFEPVAFVDALLG
MAV_3776|M.avium_104 APFEPAAFVDALLG
MLBr_01628|M.leprae_Br4923 APFEPAVFVDALLE
Mflv_4186|M.gilvum_PYR-GCK APFEPAAFVDALLG
Mvan_2177|M.vanbaalenii_PYR-1 APFEPAAFVDALLG
TH_1481|M.thermoresistible__bu APFEPAAFVDALLG
MSMEG_2424|M.smegmatis_MC2_155 APFEPGAFVDALLG
MAB_3241c|M.abscessus_ATCC_199 APFEPPAFVDALLG
***** .******