For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2920c (amt)

annotation: PROBABLE AMMONIUM-TRANSPORT INTEGRAL MEMBRANE PROTEIN AMT
coordinates: 3231073 - 3232506
length: 477

DQFPIMGVPDGGDTAWMLVSSALVLLMTPGLAFFYGGMVRSKSVLNMIMMSISAMGVVTVLWALYGYSIA
FGDDVGNIAGNPSQYWGLKGLIGVNAVAADPSTQTAAVNIPLAGTLPATVFVAFQLMFAIITVALISGAV
ADRLKFGAWLLFAGLWATFVYFPVAHWVFAFDGFAAEHGGWIANKLHAIDFAGGTAVHINAGVAALMLAI
VLGKRRGWPATLFRPHNLPFVMLGAALLWFGWYGFNAGSATTANGVAGATFVTTTIATAAAMLGWLLTER
VRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALAVGVSAGVLCALAVGLKFKLGFDDSLDVVGVHLVG
GLVGTLLVGLLAAPEAPAINGVAGVSKGLFYGGGFAQLERQALGACSVLVYSGIITLILALILKFTIGLR
LDAEQESTGIDEAEHAESGYDFAVASGSVLPPRVTVEDSRNGIQERIGQKVEAEPK*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2920camt-100% (477)PROBABLE AMMONIUM-TRANSPORT INTEGRAL MEMBRANE PROTEIN AMT

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2944camt0.0100.00% (477) ammonium transporter
M. gilvum PYR-GCKMflv_4185-1e-13255.73% (454) ammonium transporter
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3240c-0.076.37% (457) ammonium transporter
M. marinum MMMAR_1787amt0.085.32% (477) ammonium-transport integral membrane protein Amt
M. avium 104MAV_3775amt0.085.84% (473) ammonium transporter
M. smegmatis MC2 155MSMEG_2425amt1e-12954.41% (454) ammonium transporter
M. thermoresistible (build 8)TH_4321-1e-12753.23% (449) PUTATIVE ammonium transporter
M. ulcerans Agy99MUL_0037amt_11e-12050.43% (460) ammonium-transport integral membrane protein, Amt_1
M. vanbaalenii PYR-1Mvan_2178-1e-12854.07% (455) ammonium transporter

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4185|M.gilvum_PYR-GCK          ----MLLALPDEAFLPFGPEGLSAGDTAWVLTSAALVLLMTPGLAFFYGG
Mvan_2178|M.vanbaalenii_PYR-1       ----MVLALPDDAFLPFGPEGLSAGDTAWVLTSAALVLFMTPGLAFFYGG
MSMEG_2425|M.smegmatis_MC2_155      ----MVLALPDESFAAFD-----SGDTAWVLASAALVLLMTPGLAFFYGG
TH_4321|M.thermoresistible__bu      ----VVLALPDESFAAFD-----SGDTAWVLISAALVLLMTPGLAFFYGG
Rv2920c|M.tuberculosis_H37Rv        MDQFPIMGVPD------------GGDTAWMLVSSALVLLMTPGLAFFYGG
Mb2944c|M.bovis_AF2122/97           MDQFPIMGVPD------------GGDTAWMLVSSALVLLMTPGLAFFYGG
MAV_3775|M.avium_104                -MTYPILGQPN------------TGDTAWMLASSALVLLMTPGLAFFYGG
MMAR_1787|M.marinum_M               MSDFPIMGVPD------------TGDTAWMLASSALVLLMTPGLAFFYGG
MAB_3240c|M.abscessus_ATCC_199      ------MGVPN------------TGDTAWMLASAALVLLMTPGLAFFYGG
MUL_0037|M.ulcerans_Agy99           ------MDIDP-------------AATAWLLASTALVLLMTPGLAIFYGG
                                          :                 . ***:* *:****:******:****

Mflv_4185|M.gilvum_PYR-GCK          LSRQKSVLNMMMMSFGSMGVVSVIYVLWGYSMSFASAHTGESDFFGVFDN
Mvan_2178|M.vanbaalenii_PYR-1       LSRQKSVLNMMMMSFGSIGVVSVIYVLWGYSMSFASAHTGESDFFGVFDN
MSMEG_2425|M.smegmatis_MC2_155      LSRQKSVLNMMMMSFGALGVVSVIYVLWGYSMSFSSGHTGGSDIAGIFDN
TH_4321|M.thermoresistible__bu      LSRQKSVLNMMMMSFGALGIVSVVYVLWGYSMSFSSGHTGQSDILGVFDN
Rv2920c|M.tuberculosis_H37Rv        MVRSKSVLNMIMMSISAMGVVTVLWALYGYSIAFGDDVGNIAGNPSQYWG
Mb2944c|M.bovis_AF2122/97           MVRSKSVLNMIMMSISAMGVVTVLWALYGYSIAFGDDVGNIAGNPSQYWG
MAV_3775|M.avium_104                MVRARSVLNMLMMSISAMGVVTVLWVLYGYSVAFGDDVGNFMGKPTSYWG
MMAR_1787|M.marinum_M               MVRAKSVLNMIMMSISAMGVVTVLWVLYGYSVAFGNDMGGVAGNPTEYLG
MAB_3240c|M.abscessus_ATCC_199      MVRAKNVLNMIMMSISAMGLVTVLWVLYGYSMAFGNDVSGLFGNPAQFLG
MUL_0037|M.ulcerans_Agy99           MVRTTGVLNMIMMSFISIPLVTVAWLLAGYSLAFSDGAAP--GLPG----
                                    : *  .****:***: :: :*:* : * ***::*..      .       

Mflv_4185|M.gilvum_PYR-GCK          PFSLFG---VSQLTEVREIG--GVDTFVSGGFGTVPAIVWVAFQLTFAVI
Mvan_2178|M.vanbaalenii_PYR-1       PFALFG---VSQLTEVREID--GVSTYVLGGFGTVPAIVWVAFQLTFAVI
MSMEG_2425|M.smegmatis_MC2_155      PFSLFG---LSQLLETREID--GTELSVIGGFGTVPAIVWVGFQLTFAVI
TH_4321|M.thermoresistible__bu      PFSLFG---LSPLLETREID--GATLSVIGGFGTVPAIVWVGFQLTFAVI
Rv2920c|M.tuberculosis_H37Rv        LKGLIG---VNAVAADPST---QTAAVNIPLAGTLPATVFVAFQLMFAII
Mb2944c|M.bovis_AF2122/97           LKGLIG---VNAVAADPST---QTAAVNIPLAGTLPATVFVAFQLMFAII
MAV_3775|M.avium_104                LKGLIG---VNAVAADPSK---GTAATDIPLAGTLPATVFVAFQLMFAII
MMAR_1787|M.marinum_M               LKGLIG---GNGAPADPAT---QTAAVDIPLAGSLPMTVFVAFQLMFAII
MAB_3240c|M.abscessus_ATCC_199      LKGLIGGNAAEAVVADPANGVEAAEVVNIPLVGTLPATVFVAFQLMFAII
MUL_0037|M.ulcerans_Agy99           --GLVG-----GLTHAGMRG-----IGPATVHGSVPELLFATFQLSFAII
                                      .*.*                          *::*  ::. *** **:*

Mflv_4185|M.gilvum_PYR-GCK          TVALISGAVAERMKFGTWLVFGGIWVTLVYFPLAHMVWGGGLLSGAEDGI
Mvan_2178|M.vanbaalenii_PYR-1       TVALISGAVAERMKFGTWLLFGGIWVTLVYFPLSHMVWGGGLLSNADSGI
MSMEG_2425|M.smegmatis_MC2_155      TVALISGALAERVKFGTWLVFSGLWVTLVYFPLAHMVWGGGLLSDNERGF
TH_4321|M.thermoresistible__bu      TVALISGALAERVRFGTWIVFAAVWVTLVYFPLAHMVWGGGLLSDAQNGF
Rv2920c|M.tuberculosis_H37Rv        TVALISGAVADRLKFGAWLLFAGLWATFVYFPVAHWVFAFDGFAAEHGGW
Mb2944c|M.bovis_AF2122/97           TVALISGAVADRLKFGAWLLFAGLWATFVYFPVAHWVFAFDGFAAEHGGW
MAV_3775|M.avium_104                TVALISGAVSDRLKFAAWLVFAGLWATFVYFPVAHWVFAFDGFASEHGGW
MMAR_1787|M.marinum_M               TVALISGAVADRLKFGAWLLFAGLWATFVYFPVAHWVFSFDGVTAATGGW
MAB_3240c|M.abscessus_ATCC_199      TVALISGAVADRLKFGSWLLFAGLWVTVVYFPVAHWVFAFDGAAAEKGGW
MUL_0037|M.ulcerans_Agy99           TAALVSGAIADRAKFAAWMVFVPVWSIAVYSVVAHWVWAP-------SGW
                                    *.**:***:::* :*.:*::*  :*   **  ::* *:.         * 

Mflv_4185|M.gilvum_PYR-GCK          AAKLFGVDE--EG--AANVSPIDFAGGTVVHINAGMAALVLAILLGKRAG
Mvan_2178|M.vanbaalenii_PYR-1       AAKLFGLNE--DG--TASVAPIDFAGGTVVHINAGMAALVLAILLGKRTG
MSMEG_2425|M.smegmatis_MC2_155      ASWLFGTTEGDDGSVSATVAPIDFAGGTVVHINAGMAALVLAIIVGRRRN
TH_4321|M.thermoresistible__bu      ASWLFGFNE-DEG--AANVAPIDFAGGTVVHINAGMAALMLALVVGRRLG
Rv2920c|M.tuberculosis_H37Rv        IAN--------------KLHAIDFAGGTAVHINAGVAALMLAIVLGKRRG
Mb2944c|M.bovis_AF2122/97           IAN--------------KLHAIDFAGGTAVHINAGVAALMLAIVLGKRRG
MAV_3775|M.avium_104                IAN--------------KLHAIDFAGGTAVHINSGVAGLMLAIVLGKRRG
MMAR_1787|M.marinum_M               IAN--------------KLHAIDFAGGTAVHINAGVAGLVLALVLGKRRG
MAB_3240c|M.abscessus_ATCC_199      IAN--------------QLKAIDFAGGTAVHINAGTAGLVLALILGKRKG
MUL_0037|M.ulcerans_Agy99           LAK---------------MGVLDYAGGLVVEIVSGSSARALAPVLGPRIG
                                     :                :  :*:*** .*.* :* :.  ** ::* * .

Mflv_4185|M.gilvum_PYR-GCK          FGRTPYRPHNIPFVMLGAALLWFGWFGFNVGSEGAADMLAGAVWVNTTAA
Mvan_2178|M.vanbaalenii_PYR-1       FGKTPYRPHNIPFVMLGAAILWFGWFGFNVGSEGAADMLAGSVWVNTTAA
MSMEG_2425|M.smegmatis_MC2_155      FGKMAFRPHNIPWVMLGAALLWFGWFGFNVGSEGAADAVSGLVWVNTTAA
TH_4321|M.thermoresistible__bu      FGRTAYRPHNIPWVMLGAALLWFGWFGFNVGSEGAADAVAGLVWVNTTAA
Rv2920c|M.tuberculosis_H37Rv        WPATLFRPHNLPFVMLGAALLWFGWYGFNAGSATTANGVAGATFVTTTIA
Mb2944c|M.bovis_AF2122/97           WPATLFRPHNLPFVMLGAALLWFGWYGFNAGSATTANGVAGATFVTTTIA
MAV_3775|M.avium_104                WPTTLFRPHNLPFVMLGAGLLWFGWYGFNAGSATSSNGAAGSTFMTTTIA
MMAR_1787|M.marinum_M               WPTTLFRPHNLPFVMLGAGLLWFGWYGFNAGSATSSNGTAATTFVTTTVA
MAB_3240c|M.abscessus_ATCC_199      WPGTPMRPHNLPFVMLGAGLLWFGWYGFNAGSATSANGLAGSTFVTTTVA
MUL_0037|M.ulcerans_Agy99           FKVDPMRPHNLPFVLLGVGLLWFGWFGFNAGSALAANGLASAIFLNTLVA
                                    :     ****:*:*:**..:*****:***.**  :::  :.  ::.*  *

Mflv_4185|M.gilvum_PYR-GCK          TAAAMLGWLLVERIRDGHATSVGAASGIVAGLVAITPACGSLSAIGSVIL
Mvan_2178|M.vanbaalenii_PYR-1       TAAAMLAWLVVERIRDGHATSVGAASGIVAGLVAITPACGALSAIGSLIL
MSMEG_2425|M.smegmatis_MC2_155      TAAAMLGWLLVERIRDGHPTSVGAASGIVAGLVAITPACGALSPVGSLIL
TH_4321|M.thermoresistible__bu      TAAAMLGWLIVERIRDGRPTSVGAASGIVAGLVAITPACGALSPVGSLFL
Rv2920c|M.tuberculosis_H37Rv        TAAAMLGWLLTERVRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALAV
Mb2944c|M.bovis_AF2122/97           TAAAMLGWLLTERVRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALAV
MAV_3775|M.avium_104                TATAMLAWMLTERIRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALVV
MMAR_1787|M.marinum_M               TAAAMLAWLLTERIRDGKATTLGAASGIVAGLVAITPSCSSVNVLGALVV
MAB_3240c|M.abscessus_ATCC_199      TAAAMLGWLLTERIRDGHATSLGAASGIVAGLVAITPSCSSVNVLGALAI
MUL_0037|M.ulcerans_Agy99           GCLGMLGWLAVEQIRDGKPTTFGAASGVVAGLVAITPSCGTVNPLGAALI
                                     . .**.*: .*::***:.*:.*****:*********:*.::. :*:  :

Mflv_4185|M.gilvum_PYR-GCK          GAVAGVLSALAIALKYKFGYDDSLDVVGVHLVAGLWGTIGIGFLA-----
Mvan_2178|M.vanbaalenii_PYR-1       GAVAGVLSALAISLKYKFGYDDSLDVVGVHLVAGLWGTVGIGFLA-----
MSMEG_2425|M.smegmatis_MC2_155      GAIAGALSALAISLKYKFGYDDSLDVVGVHLVAGLWGTVAIGLFA-----
TH_4321|M.thermoresistible__bu      GVIAGALSALAVGLKYRFGYDDSLDVVGVHLVAGLWGTIGIGFFA-----
Rv2920c|M.tuberculosis_H37Rv        GVSAGVLCALAVGLKFKLGFDDSLDVVGVHLVGGLVGTLLVGLLAAPEAP
Mb2944c|M.bovis_AF2122/97           GVSAGVLCALAVGLKFKLGFDDSLDVVGVHLVGGLVGTLLVGLLAAPEAP
MAV_3775|M.avium_104                GLVAGVVCALAVGLKFKLGFDDSLDVVGVHLVGGLAGTLLVGLLAAPESP
MMAR_1787|M.marinum_M               GAVAGVLCALAVGLKFRLGFDDSLDVVGVHLVGGLAGTLLVGLMAAPESP
MAB_3240c|M.abscessus_ATCC_199      GAIAGILCALAVGLKYRLGFDDSLDVVGVHLVGGIVGTLLIGLFAAPET-
MUL_0037|M.ulcerans_Agy99           GLAAGIVCAFAITVKFKLNYDDSLDVVGVHFIGGVVGVLLIGLLATAVMT
                                    *  ** :.*:*: :*:::.:**********::.*: *.: :*::*     

Mflv_4185|M.gilvum_PYR-GCK          -------LETGLFYGGGFEQLVVQIVIALVAVVFTAVMTAIIAFIVKP-L
Mvan_2178|M.vanbaalenii_PYR-1       -------TETGLFYGGGVQQLVVQAVIALVAVVFTAIMTAIIAFIVKP-L
MSMEG_2425|M.smegmatis_MC2_155      -------TETGLFYGGGIQQLVVQIVIAVVATVFTAVMTAIIALALKP-M
TH_4321|M.thermoresistible__bu      -------TETGLLYGGGIQQLIVQIVIAVVAMAFTAVMTLVIATVLKP-L
Rv2920c|M.tuberculosis_H37Rv        AINGVAGVSKGLFYGGGFAQLERQALGACSVLVYSGIITLILALILKFTI
Mb2944c|M.bovis_AF2122/97           AINGVAGVSKGLFYGGGFAQLERQALGACSVLVYSGIITLILALILKFTI
MAV_3775|M.avium_104                AISGVTGVSKGLFYGGGWAQLERQAVGAFSVLIYSGVVTLILALILKYTM
MMAR_1787|M.marinum_M               AINGVEGVSKGLFYGGGFDQLVRQAVGASSVLIYSGVVTFILALILKYTI
MAB_3240c|M.abscessus_ATCC_199      -----GAAVAGLFYGGGLEQLWRQAVGAGAVLLYSAIGTAIVAFIVKYTI
MUL_0037|M.ulcerans_Agy99           ------DGARGLFYGGGLGQLGKQALAMVVVGLYAFTVSYLLAALIERLM
                                              **:****  **  * :    .  ::   : ::*  ::  :

Mflv_4185|M.gilvum_PYR-GCK          GWRVSKEDEDTGIDETEHAETAYELA------------------------
Mvan_2178|M.vanbaalenii_PYR-1       GWRVSKEDEDTGIDETEHAETAYELA------------------------
MSMEG_2425|M.smegmatis_MC2_155      GWRVTDEDEATGIDETEHAETAYELA------------------------
TH_4321|M.thermoresistible__bu      GWRVSEEDEEAGIDAAEHAETAYELV------------------------
Rv2920c|M.tuberculosis_H37Rv        GLRLDAEQESTGIDEAEHAESGYDF-AVASGSVLPPRVTVEDSRNGIQER
Mb2944c|M.bovis_AF2122/97           GLRLDAEQESTGIDEAEHAESGYDF-AVASGSVLPPRVTVEDSRNGIQER
MAV_3775|M.avium_104                GLRLNPEAEASGIDEAEHAESGYDF-AVATGSVLPPRVAVADTRNGLEEQ
MMAR_1787|M.marinum_M               GLRLGPEQESAGIDEAEHAENGYDF-AVASGSVLPRPGIVADSRNGLEER
MAB_3240c|M.abscessus_ATCC_199      GLRISDEGEAAGADESQHAEGAYDFVALGSGSVIGRHVSSGSSD------
MUL_0037|M.ulcerans_Agy99           GFRVSREEEVSGVDFSQHAETAYTEGVYGHQQLHRPFSGGDAIRPRPNIE
                                    * *:  * * :* * ::*** .*                           

Mflv_4185|M.gilvum_PYR-GCK          -----------
Mvan_2178|M.vanbaalenii_PYR-1       -----------
MSMEG_2425|M.smegmatis_MC2_155      -----------
TH_4321|M.thermoresistible__bu      -----------
Rv2920c|M.tuberculosis_H37Rv        -IGQKVEAEPK
Mb2944c|M.bovis_AF2122/97           -IGQKVEAEPK
MAV_3775|M.avium_104                RVGDKVEAEQS
MMAR_1787|M.marinum_M               -VGEKVEAEPK
MAB_3240c|M.abscessus_ATCC_199      -----------
MUL_0037|M.ulcerans_Agy99           DA---------